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Christel Herold-Mende
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Journal Articles

Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Valentina Fermi, Rolf Warta, Amélie Wöllner, Catharina Lotsch, Lena Jassowicz, Carmen Rapp, Maximilian Knoll, Gerhard Jungwirth, Christine Jungk, Philip Dao Trong, Andreas von Deimling, Amir Abdollahi, Andreas Unterberg, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (22): 4685–4697.
https://doi.org/10.1158/1078-0432.CCR-23-0576
Published: 14 November 2023
View article titled, Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580
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Includes: Supplementary data
Journal Articles

DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy

Bouchra Tawk, Katrin Rein, Christian Schwager, Maximilian Knoll, Ute Wirkner, Juliane Hörner-Rieber, Jakob Liermann, Ina Kurth, Panagiotis Balermpas, Claus Rödel, Annett Linge, Steffen Löck, Fabian Lohaus, Ingeborg Tinhofer, Mechtild Krause, Martin Stuschke, Anca Ligia Grosu, Daniel Zips, Stephanie E. Combs, Claus Belka, Albrecht Stenzinger, Christel Herold-Mende, Michael Baumann, Peter Schirmacher, Jürgen Debus, Amir Abdollahi
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (16): 3051–3064.
https://doi.org/10.1158/1078-0432.CCR-22-3790
Published: 15 August 2023
View article titled, DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy
Open the PDF for DNA-Methylome–Based Tumor Hypoxia Classifier Identifies HPV-Negative Head and Neck Cancer Patients at Risk for Locoregional Recurrence after Primary Radiochemotherapy in another window
Includes: Supplementary data
Journal Articles

A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma

Sied Kebir, Vivien Ullrich, Pia Berger, Celia Dobersalske, Sarah Langer, Laurèl Rauschenbach, Daniel Trageser, Andreas Till, Franziska K. Lorbeer, Anja Wieland, Timo Wilhelm-Buchstab, Ashar Ahmad, Holger Fröhlich, Igor Cima, Shruthi Prasad, Johann Matschke, Verena Jendrossek, Marc Remke, Barbara M. Grüner, Alexander Roesch, Jens T. Siveke, Christel Herold-Mende, Tobias Blau, Kathy Keyvani, Frank K.H. van Landeghem, Torsten Pietsch, Jörg Felsberg, Guido Reifenberger, Michael Weller, Ulrich Sure, Oliver Brüstle, Matthias Simon, Martin Glas, Björn Scheffler
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (2): 488–500.
https://doi.org/10.1158/1078-0432.CCR-22-0611
Published: 17 January 2023
View article titled, A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma
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Includes: Supplementary data
Journal Articles

Pharmacological Landscape of FDA-Approved Anticancer Drugs Reveals Sensitivities to Ixabepilone, Romidepsin, Omacetaxine, and Carfilzomib in Aggressive Meningiomas

Gerhard Jungwirth, Tao Yu, Fang Liu, Junguo Cao, Montadar Alaa Eddine, Mahmoud Moustafa, Amir Abdollahi, Rolf Warta, Andreas Unterberg, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 233–243.
https://doi.org/10.1158/1078-0432.CCR-22-2085
Published: 04 January 2023
View article titled, Pharmacological Landscape of FDA-Approved Anticancer Drugs Reveals Sensitivities to Ixabepilone, Romidepsin, Omacetaxine, and Carfilzomib in Aggressive Meningiomas
Open the PDF for Pharmacological Landscape of FDA-Approved Anticancer Drugs Reveals Sensitivities to Ixabepilone, Romidepsin, Omacetaxine, and Carfilzomib in Aggressive Meningiomas in another window
Includes: Supplementary data
Journal Articles

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, J.P. Martinez-Barbera, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kuhn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold-Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David T.W. Jones, Olaf Witt, Till Milde
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1851–1866.
https://doi.org/10.1158/1078-0432.CCR-18-1965
Published: 15 March 2019
View article titled, The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma
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Includes: Supplementary data
Journal Articles

Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation

Tom B. Davidson, Alexander Lee, Melody Hsu, Shaina Sedighim, Joey Orpilla, Janet Treger, Max Mastall, Saskia Roesch, Carmen Rapp, Mildred Galvez, Aaron Mochizuki, Joseph Antonios, Alejandro Garcia, Nikesh Kotecha, Nicholas Bayless, David Nathanson, Anthony Wang, Richard Everson, William H. Yong, Timothy F. Cloughesy, Linda M. Liau, Christel Herold-Mende, Robert M. Prins
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1913–1922.
https://doi.org/10.1158/1078-0432.CCR-18-1176
Published: 15 March 2019
View article titled, Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation
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Includes: Supplementary data
Journal Articles

Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma

Steffen Dettling, Slava Stamova, Rolf Warta, Martina Schnölzer, Carmen Rapp, Anchana Rathinasamy, David Reuss, Kolja Pocha, Saskia Roesch, Christine Jungk, Uwe Warnken, Volker Eckstein, Niels Grabe, Christoph Schramm, Markus A. Weigand, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (12): 2951–2962.
https://doi.org/10.1158/1078-0432.CCR-17-1839
Published: 14 June 2018
View article titled, Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma
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Includes: Supplementary data
Journal Articles

Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display

Annette Altmann, Max Sauter, Saskia Roesch, Walter Mier, Rolf Warta, Jürgen Debus, Gerhard Dyckhoff, Christel Herold-Mende, Uwe Haberkorn
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (15): 4170–4180.
https://doi.org/10.1158/1078-0432.CCR-16-3217
Published: 01 August 2017
View article titled, Identification of a Novel ITGα<sub>v</sub>β<sub>6</sub>-Binding Peptide Using Protein Separation and Phage Display
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Includes: Supplementary data
Journal Articles

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

Jennifer Lohr, Thomas Ratliff, Andrea Huppertz, Yingzi Ge, Christine Dictus, Rezvan Ahmadi, Stefan Grau, Nobuyoshi Hiraoka, Volker Eckstein, Rupert C. Ecker, Thomas Korff, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4296–4308.
https://doi.org/10.1158/1078-0432.CCR-10-2557
Published: 05 July 2011
View article titled, Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β
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Includes: Supplementary data
Journal Articles

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

Benito Campos, Feng Wan, Mohammad Farhadi, Aurélie Ernst, Felix Zeppernick, Katrin E. Tagscherer, Rezvan Ahmadi, Jennifer Lohr, Christine Dictus, Georg Gdynia, Stephanie E. Combs, Violaine Goidts, Burkhard M. Helmke, Volker Eckstein, Wilfried Roth, Philipp Beckhove, Peter Lichter, Andreas Unterberg, Bernhard Radlwimmer, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (10): 2715–2728.
https://doi.org/10.1158/1078-0432.CCR-09-1800
Published: 13 May 2010
View article titled, Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
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Includes: Supplementary data
Journal Articles

Genomic and Expression Profiling of Glioblastoma Stem Cell–Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival

Aurélie Ernst, Stefanie Hofmann, Rezvan Ahmadi, Natalia Becker, Andrey Korshunov, Felix Engel, Christian Hartmann, Jörg Felsberg, Michael Sabel, Heike Peterziel, Moritz Durchdewald, Jochen Hess, Sebastian Barbus, Benito Campos, Anna Starzinski-Powitz, Andreas Unterberg, Guido Reifenberger, Peter Lichter, Christel Herold-Mende, Bernhard Radlwimmer
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (21): 6541–6550.
https://doi.org/10.1158/1078-0432.CCR-09-0695
Published: 02 November 2009
View article titled, Genomic and Expression Profiling of Glioblastoma Stem Cell–Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival
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Includes: Supplementary data
Journal Articles

Heparanase Expression at the Invasion Front of Human Head and Neck Cancers and Correlation with Poor Prognosis

Philipp Beckhove, Burkhard M. Helmke, Yvonne Ziouta, Mariana Bucur, Wolfgang Dörner, Carolin Mogler, Gerhard Dyckhoff, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (8): 2899–2906.
https://doi.org/10.1158/1078-0432.CCR-04-0664
Published: 18 April 2005
View article titled, Heparanase Expression at the Invasion Front of Human Head and Neck Cancers and Correlation with Poor Prognosis
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