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Charlotte K.Y. Ng
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Journal Articles

Hepatocellular Carcinoma Immune Microenvironment Analysis: A Comprehensive Assessment with Computational and Classical Pathology

Caner Ercan, Salvatore Lorenzo Renne, Luca Di Tommaso, Charlotte K.Y. Ng, Salvatore Piscuoglio, Luigi M. Terracciano
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (22): 5105–5115.
https://doi.org/10.1158/1078-0432.CCR-24-0960
Published: 15 November 2024
View article titled, Hepatocellular Carcinoma Immune Microenvironment Analysis: A Comprehensive Assessment with Computational and Classical Pathology
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Includes: Supplementary data
Journal Articles

Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma

Ju Youn Lee, Michail Schizas, Felipe C. Geyer, Pier Selenica, Salvatore Piscuoglio, Rita A. Sakr, Charlotte K.Y. Ng, Jose V. Scarpa Carniello, Russell Towers, Dilip D. Giri, Victor P. de Andrade, Anastasios D. Papanastasiou, Agnes Viale, Reuben S. Harris, David B. Solit, Britta Weigelt, Jorge S. Reis-Filho, Tari A. King
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (2): 674–686.
https://doi.org/10.1158/1078-0432.CCR-18-1103
Published: 15 January 2019
View article titled, Lobular Carcinomas <em>In Situ</em> Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma
Open the PDF for Lobular Carcinomas <em>In Situ</em> Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer

Britta Weigelt, Iñaki Comino-Méndez, Ino de Bruijn, Lei Tian, Jane L. Meisel, Isaac García-Murillas, Charlotte Fribbens, Ros Cutts, Luciano G. Martelotto, Charlotte K.Y. Ng, Raymond S. Lim, Pier Selenica, Salvatore Piscuoglio, Carol Aghajanian, Larry Norton, Rajmohan Murali, David M. Hyman, Laetitia Borsu, Maria E. Arcila, Jason Konner, Jorge S. Reis-Filho, Roger A. Greenberg, Mark E. Robson, Nicholas C. Turner
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (21): 6708–6720.
https://doi.org/10.1158/1078-0432.CCR-17-0544
Published: 31 October 2017
View article titled, Diverse <em>BRCA1</em> and <em>BRCA2</em> Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer
Open the PDF for Diverse <em>BRCA1</em> and <em>BRCA2</em> Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

Xiaowei Xu, Carmine De Angelis, Kathleen A. Burke, Agostina Nardone, Huizhong Hu, Lanfang Qin, Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Laura M. Heiser, Nicholas Wang, Charlotte K.Y. Ng, Edward S. Chen, Alexander Renwick, Tao Wang, Sarmistha Nanda, Martin Shea, Tamika Mitchell, Mahitha Rajendran, Ian Waters, Daniel J. Zabransky, Kenneth L. Scott, Carolina Gutierrez, Chandandeep Nagi, Felipe C. Geyer, Gary C. Chamness, Ben H. Park, Chad A. Shaw, Susan G. Hilsenbeck, Mothaffar F. Rimawi, Joe W. Gray, Britta Weigelt, Jorge S. Reis-Filho, C. Kent Osborne, Rachel Schiff
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (17): 5123–5134.
https://doi.org/10.1158/1078-0432.CCR-16-2191
Published: 31 August 2017
View article titled, HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2<sup>+</sup> Breast Cancer
Open the PDF for HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2<sup>+</sup> Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases

Charlotte K.Y. Ng, Francois-Clement Bidard, Salvatore Piscuoglio, Felipe C. Geyer, Raymond S. Lim, Ino de Bruijn, Ronglai Shen, Fresia Pareja, Samuel H. Berman, Lu Wang, Jean-Yves Pierga, Anne Vincent-Salomon, Agnes Viale, Larry Norton, Brigitte Sigal, Britta Weigelt, Paul Cottu, Jorge S. Reis-Filho
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 4402–4415.
https://doi.org/10.1158/1078-0432.CCR-16-3115
Published: 01 August 2017
View article titled, Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases
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Includes: Supplementary data
Journal Articles

The Landscape of Somatic Genetic Alterations in Metaplastic Breast Carcinomas

Charlotte K.Y. Ng, Salvatore Piscuoglio, Felipe C. Geyer, Kathleen A. Burke, Fresia Pareja, Carey A. Eberle, Raymond S. Lim, Rachael Natrajan, Nadeem Riaz, Odette Mariani, Larry Norton, Anne Vincent-Salomon, Y. Hannah Wen, Britta Weigelt, Jorge S. Reis-Filho
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (14): 3859–3870.
https://doi.org/10.1158/1078-0432.CCR-16-2857
Published: 13 July 2017
View article titled, The Landscape of Somatic Genetic Alterations in Metaplastic Breast Carcinomas
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Includes: Supplementary data
Journal Articles

The Genomic Landscape of Male Breast Cancers

Salvatore Piscuoglio, Charlotte K.Y. Ng, Melissa P. Murray, Elena Guerini-Rocco, Luciano G. Martelotto, Felipe C. Geyer, Francois-Clement Bidard, Samuel Berman, Nicola Fusco, Rita A. Sakr, Carey A. Eberle, Leticia De Mattos-Arruda, Gabriel S. Macedo, Muzaffar Akram, Timour Baslan, James B. Hicks, Tari A. King, Edi Brogi, Larry Norton, Britta Weigelt, Clifford A. Hudis, Jorge S. Reis-Filho
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16): 4045–4056.
https://doi.org/10.1158/1078-0432.CCR-15-2840
Published: 14 August 2016
View article titled, The Genomic Landscape of Male Breast Cancers
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Includes: Supplementary data
Journal Articles

PI3K Pathway Activation in High-Grade Ductal Carcinoma In Situ—Implications for Progression to Invasive Breast Carcinoma

Rita A. Sakr, Britta Weigelt, Sarat Chandarlapaty, Victor P. Andrade, Elena Guerini-Rocco, Dilip Giri, Charlotte K.Y. Ng, Catherine F. Cowell, Neal Rosen, Jorge S. Reis-Filho, Tari A. King
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2326–2337.
https://doi.org/10.1158/1078-0432.CCR-13-2267
Published: 30 April 2014
View article titled, PI3K Pathway Activation in High-Grade Ductal Carcinoma <em>In Situ</em>—Implications for Progression to Invasive Breast Carcinoma
Open the PDF for PI3K Pathway Activation in High-Grade Ductal Carcinoma <em>In Situ</em>—Implications for Progression to Invasive Breast Carcinoma in another window
Includes: Supplementary data