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Celeste Lebbé
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Journal Articles

The CD70–CD27 Axis in Cancer Immunotherapy: Predictive Biomarker and Therapeutic Target

Available to Purchase
Ikuan Sam, Nadine Ben Hamouda, Marina Alkatrib, Cecile Gonnin, Peter J. Siska, Stephane Oudard, Céleste Lebbé, Eric Tartour
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (14): 2872–2881.
https://doi.org/10.1158/1078-0432.CCR-24-2668
Published: 15 July 2025
View article titled, The CD70–CD27 Axis in Cancer Immunotherapy: Predictive Biomarker and Therapeutic Target
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Journal Articles

A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors

Open Access
Oliver Bechter, Carmen Loquai, Stephane Champiat, Jean-Francois Baurain, Jean-Jacques Grob, Jochen Utikal, Sylvie Rottey, Alfonso Berrocal, Jessica C. Hassel, Ana Arance, Miguel F. Sanmamed, Marye Boers-Sonderen, Brian Gastman, Christoffer Gebhardt, Brant Delafontaine, Ugur Sahin, Özlem Türeci, Patrick Brueck, Giovanni Abbadessa, Rahul Marpadga, Helen Lee, Yue Yang, Barbara Buday, Gianfranco Di Genova, Hong Wang, Binfeng Xia, Joon Sang Lee, Céleste Lebbe
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (12): 2358–2369.
https://doi.org/10.1158/1078-0432.CCR-24-1983
Published: 13 June 2025
View article titled, A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors
Open the PDF for A Phase I, First-in-Human, Dose-Escalation, Expansion Trial of Cytokine-Encoding Synthetic mRNA Mixture Alone or with Cemiplimab in Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Biomarker Analyses Investigating Disease Biology and Associations with Outcomes in the JAVELIN Merkel 200 Trial of Avelumab in Metastatic Merkel Cell Carcinoma

Open Access
Sandra P. D’Angelo, Céleste Lebbé, Paul Nghiem, Andrew S. Brohl, Thomas Mrowiec, Trent Leslie, Sara Georges, Gülseren Güzel, Parantu Shah
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (19): 4352–4362.
https://doi.org/10.1158/1078-0432.CCR-23-0395
Published: 01 October 2024
View article titled, Biomarker Analyses Investigating Disease Biology and Associations with Outcomes in the JAVELIN Merkel 200 Trial of Avelumab in Metastatic Merkel Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Phase I Study of Androgen Deprivation Therapy in Combination with Anti–PD-1 in Melanoma Patients Pretreated with Anti–PD-1

Available to Purchase
Caroline Robert, Céleste Lebbé, Thierry Lesimple, Eija Lundström, Valérie Nicolas, Bruno Gavillet, Philippa Crompton, Barouyr Baroudjian, Emilie Routier, Ferdy J. Lejeune
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (5): 858–865.
https://doi.org/10.1158/1078-0432.CCR-22-2812
Published: 01 March 2023
View article titled, Phase I Study of Androgen Deprivation Therapy in Combination with Anti–PD-1 in Melanoma Patients Pretreated with Anti–PD-1
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Includes: Supplementary data
Journal Articles

Phase I–II Open-Label Multicenter Study of Palbociclib + Vemurafenib in BRAFV600MUT Metastatic Melanoma Patients: Uncovering CHEK2 as a Major Response Mechanism

Available to Purchase
Baptiste Louveau, Matthieu Resche-Rigon, Thierry Lesimple, Laetitia Da Meda, Marc Pracht, Barouyr Baroudjian, Julie Delyon, Mona Amini-Adle, Caroline Dutriaux, Coralie Reger de Moura, Aurélie Sadoux, Fanélie Jouenne, Zineb Ghrieb, Paul Vilquin, Didier Bouton, Annick Tibi, Samuel Huguet, Keyvan Rezai, Maxime Battistella, Samia Mourah, Céleste Lebbe
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 3876–3883.
https://doi.org/10.1158/1078-0432.CCR-20-4050
Published: 15 July 2021
View article titled, Phase I–II Open-Label Multicenter Study of Palbociclib + Vemurafenib in BRAFV600MUT Metastatic Melanoma Patients: Uncovering CHEK2 as a Major Response Mechanism
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Includes: Supplementary data
Journal Articles

A Phase Ib/II Study of the BRAF Inhibitor Encorafenib Plus the MEK Inhibitor Binimetinib in Patients with BRAFV600E/K-mutant Solid Tumors

Free
Ryan J. Sullivan, Jeffrey Weber, Sapna Patel, Reinhard Dummer, Matteo S. Carlino, Daniel S.W. Tan, Celeste Lebbé, Salvatore Siena, Elena Elez, Lance Wollenberg, Michael D. Pickard, Victor Sandor, Paolo A. Ascierto
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (19): 5102–5112.
https://doi.org/10.1158/1078-0432.CCR-19-3550
Published: 01 October 2020
View article titled, A Phase Ib/II Study of the BRAF Inhibitor Encorafenib Plus the MEK Inhibitor Binimetinib in Patients with BRAFV600E/K-mutant Solid Tumors
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Includes: Supplementary data
Journal Articles

Imatinib Mesylate as a Preoperative Therapy in Dermatofibrosarcoma: Results of a Multicenter Phase II Study on 25 Patients

Free
Delphine Kérob, Raphael Porcher, Olivier Vérola, Stephane Dalle, Eve Maubec, François Aubin, Michel D'Incan, Isaak Bodokh, Serge Boulinguez, Isabelle Madelaine-Chambrin, Anne Mathieu-Boue, Jean-Marie Servant, Eric de Kerviler, Anne Janin, Fabien Calvo, Florence Pedeutour, Celeste Lebbe
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (12): 3288–3295.
https://doi.org/10.1158/1078-0432.CCR-09-3401
Published: 14 June 2010
View article titled, Imatinib Mesylate as a Preoperative Therapy in Dermatofibrosarcoma: Results of a Multicenter Phase II Study on 25 Patients
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Includes: Supplementary data
Journal Articles

Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria

Free
Jedd D. Wolchok, Axel Hoos, Steven O'Day, Jeffrey S. Weber, Omid Hamid, Celeste Lebbé, Michele Maio, Michael Binder, Oliver Bohnsack, Geoffrey Nichol, Rachel Humphrey, F. Stephen Hodi
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7412–7420.
https://doi.org/10.1158/1078-0432.CCR-09-1624
Published: 30 November 2009
View article titled, Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria
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Includes: Supplementary data