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Bruce Montgomery
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Journal Articles

Circulating and Intratumoral Adrenal Androgens Correlate with Response to Abiraterone in Men with Castration-Resistant Prostate Cancer

Elahe A. Mostaghel, Brett T. Marck, Orpheus Kolokythas, Felix Chew, Evan Y. Yu, Michael T. Schweizer, Heather H. Cheng, Phillip W. Kantoff, Steven P. Balk, Mary-Ellen Taplin, Nima Sharifi, Alvin M. Matsumoto, Peter S. Nelson, R. Bruce Montgomery
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 6001–6011.
https://doi.org/10.1158/1078-0432.CCR-21-1819
Published: 01 November 2021
View article titled, Circulating and Intratumoral Adrenal Androgens Correlate with Response to Abiraterone in Men with Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance

Rana R. McKay, Lucia Kwak, Jett P. Crowdis, Jamie M. Sperger, Shuang G. Zhao, Wanling Xie, Lillian Werner, Rosina T. Lis, Zhenwei Zhang, Xiao X. Wei, Joshua M. Lang, Eliezer M. Van Allen, Rupal S. Bhatt, Evan Y. Yu, Peter S. Nelson, Glenn J. Bubley, R. Bruce Montgomery, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3610–3619.
https://doi.org/10.1158/1078-0432.CCR-20-4616
Published: 01 July 2021
View article titled, Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance
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Includes: Supplementary data
Journal Articles

Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies

Yi Liang, Sujeeve Jeganathan, Stefano Marastoni, Adam Sharp, Ines Figueiredo, Richard Marcellus, Amanda Mawson, Zvi Shalev, Aleksandra Pesic, Joan Sweet, Haiyang Guo, David Uehling, Bora Gurel, Antje Neeb, Housheng Hansen He, Bruce Montgomery, Marianne Koritzinsky, Samantha Oakes, Johann S. de Bono, Martin Gleave, Amina Zoubeidi, Bradly G. Wouters, Anthony M. Joshua
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2340–2351.
https://doi.org/10.1158/1078-0432.CCR-20-3260
Published: 15 April 2021
View article titled, Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies
Open the PDF for Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies in another window
Includes: Supplementary data
Journal Articles

AR-Variant–Positive CTC: A Surrogate for a Surrogate for Taxane Therapy Outcome?

Scott M. Dehm, Bruce Montgomery, Stephen R. Plymate
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1696–1698.
https://doi.org/10.1158/1078-0432.CCR-18-3727
Published: 15 March 2019
View article titled, AR-Variant–Positive CTC: A Surrogate for a Surrogate for Taxane Therapy Outcome?
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Journal Articles

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

Himisha Beltran, Clara Oromendia, Daniel C. Danila, Bruce Montgomery, Christopher Hoimes, Russell Z. Szmulewitz, Ulka Vaishampayan, Andrew J. Armstrong, Mark Stein, Jacek Pinski, Juan M. Mosquera, Verena Sailer, Rohan Bareja, Alessandro Romanel, Naveen Gumpeni, Andrea Sboner, Etienne Dardenne, Loredana Puca, Davide Prandi, Mark A. Rubin, Howard I. Scher, David S. Rickman, Francesca Demichelis, David M. Nanus, Karla V. Ballman, Scott T. Tagawa
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 43–51.
https://doi.org/10.1158/1078-0432.CCR-18-1912
Published: 03 January 2019
View article titled, A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers
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Includes: Supplementary data
Journal Articles

Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer

Elahe A. Mostaghel, Eunpi Cho, Ailin Zhang, Mohammad Alyamani, Arja Kaipainen, Sean Green, Brett T. Marck, Nima Sharifi, Jonathan L. Wright, Roman Gulati, Lawrence D. True, Massimo Loda, Alvin M. Matsumoto, Daniel Tamae, Trevor N. Penning, Steven P. Balk, Phillip W. Kantoff, Peter S. Nelson, Mary-Ellen Taplin, R. Bruce Montgomery
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (16): 4592–4601.
https://doi.org/10.1158/1078-0432.CCR-16-2245
Published: 14 August 2017
View article titled, Association of Tissue Abiraterone Levels and <em>SLCO</em> Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer
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Includes: Supplementary data
Journal Articles

Neoadjuvant Enzalutamide Prior to Prostatectomy

Bruce Montgomery, Maria S. Tretiakova, Anthony M. Joshua, Martin E. Gleave, Neil Fleshner, Glenn J. Bubley, Elahe A. Mostaghel, Kim N. Chi, Daniel W. Lin, Martin Sanda, William Novotny, Kenneth Wu, Philip W. Kantoff, Brett T. Marck, Stephen Plymate, Steven P. Balk, Peter S. Nelson, Alvin M. Matsumoto, Rosina T. Lis, Adam Kibel, Gabriel P. Haas, Andrew Krivoshik, Alison Hannah, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (9): 2169–2176.
https://doi.org/10.1158/1078-0432.CCR-16-1357
Published: 30 April 2017
View article titled, Neoadjuvant Enzalutamide Prior to Prostatectomy
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Includes: Supplementary data
Journal Articles

A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer

Rana R. McKay, Lillian Werner, Elahe A. Mostaghel, Rosina Lis, Olga Voznesensky, Zhenwei Zhang, Brett T. Marck, Alvin M. Matsumoto, Liran Domachevsky, Katherine A. Zukotynski, Manoj Bhasin, Glenn J. Bubley, Bruce Montgomery, Philip W. Kantoff, Steven P. Balk, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (4): 935–945.
https://doi.org/10.1158/1078-0432.CCR-16-0987
Published: 14 February 2017
View article titled, A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Androgen Receptor Modulation Optimized for Response (ARMOR) Phase I and II Studies: Galeterone for the Treatment of Castration-Resistant Prostate Cancer

Bruce Montgomery, Mario A. Eisenberger, Matthew B. Rettig, Franklin Chu, Roberto Pili, Joseph J. Stephenson, Nicholas J. Vogelzang, Alan J. Koletsky, Luke T. Nordquist, William J. Edenfield, Khalid Mamlouk, Karen J. Ferrante, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (6): 1356–1363.
https://doi.org/10.1158/1078-0432.CCR-15-1432
Published: 14 March 2016
View article titled, Androgen Receptor Modulation Optimized for Response (ARMOR) Phase I and II Studies: Galeterone for the Treatment of Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Xiaotun Zhang, Ilsa M. Coleman, Lisha G. Brown, Lawrence D. True, Lori Kollath, Jared M. Lucas, Hung-Ming Lam, Ruth Dumpit, Eva Corey, Lisly Chéry, Bryce Lakely, Celestia S. Higano, Bruce Montgomery, Martine Roudier, Paul H. Lange, Peter S. Nelson, Robert L. Vessella, Colm Morrissey
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4698–4708.
https://doi.org/10.1158/1078-0432.CCR-15-0157
Published: 14 October 2015
View article titled, SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit

Elahe A. Mostaghel, Stephen R. Plymate, Bruce Montgomery
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (4): 791–798.
https://doi.org/10.1158/1078-0432.CCR-12-3601
Published: 16 February 2014
View article titled, Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit
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Journal Articles

Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants

Elahe A. Mostaghel, Brett T. Marck, Stephen R. Plymate, Robert L. Vessella, Stephen Balk, Alvin M. Matsumoto, Peter S. Nelson, R. Bruce Montgomery
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (18): 5913–5925.
https://doi.org/10.1158/1078-0432.CCR-11-0728
Published: 14 September 2011
View article titled, Resistance to CYP17A1 Inhibition with Abiraterone in Castration-Resistant Prostate Cancer: Induction of Steroidogenesis and Androgen Receptor Splice Variants
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Includes: Supplementary data
Journal Articles

Quantitative Analysis of Circulating Tumor Cells as a Survival Predictor in Metastatic Castration–Resistant Prostate Cancer: Missing Parts in a Superb Study

Johann S. de Bono, Christopher Parker, Howard I. Scher, R. Bruce Montgomery, M. Craig Miller, Henk Tissing, Gerald V. Doyle, Leon W.W.M. Terstappen, Kenneth J. Pienta, Derek Raghavan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (4): 1504–1505.
https://doi.org/10.1158/1078-0432.CCR-09-0006
Published: 19 February 2009
View article titled, Quantitative Analysis of Circulating Tumor Cells as a Survival Predictor in Metastatic Castration–Resistant Prostate Cancer: Missing Parts in a Superb Study
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Journal Articles

Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

Johann S. de Bono, Howard I. Scher, R. Bruce Montgomery, Christopher Parker, M. Craig Miller, Henk Tissing, Gerald V. Doyle, Leon W.W.M. Terstappen, Kenneth J. Pienta, Derek Raghavan
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19): 6302–6309.
https://doi.org/10.1158/1078-0432.CCR-08-0872
Published: 30 September 2008
View article titled, Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer
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Journal Articles

An Antibody Targeting the Type I Insulin-like Growth Factor Receptor Enhances the Castration-Induced Response in Androgen-Dependent Prostate Cancer

Stephen R. Plymate, Kathy Haugk, Ilsa Coleman, Lillie Woodke, Robert Vessella, Peter Nelson, R. Bruce Montgomery, Dale L. Ludwig, Jennifer D. Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (21): 6429–6439.
https://doi.org/10.1158/1078-0432.CCR-07-0648
Published: 01 November 2007
View article titled, An Antibody Targeting the Type I Insulin-like Growth Factor Receptor Enhances the Castration-Induced Response in Androgen-Dependent Prostate Cancer
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Journal Articles

Combined In vivo Effect of A12, a Type 1 Insulin-Like Growth Factor Receptor Antibody, and Docetaxel against Prostate Cancer Tumors

Jennifer D. Wu, Kathy Haugk, Ilsa Coleman, Lillie Woodke, Robert Vessella, Peter Nelson, R. Bruce Montgomery, Dale L. Ludwig, Stephen R. Plymate
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (20): 6153–6160.
https://doi.org/10.1158/1078-0432.CCR-06-0443
Published: 24 October 2006
View article titled, Combined <em>In vivo</em> Effect of A12, a Type 1 Insulin-Like Growth Factor Receptor Antibody, and Docetaxel against Prostate Cancer Tumors
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Journal Articles

Characterization of Chemical Constituents in Scutellaria baicalensis with Antiandrogenic and Growth-Inhibitory Activities toward Prostate Carcinoma

Michael Bonham, Jeff Posakony, Ilsa Coleman, Bruce Montgomery, Julian Simon, Peter S. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (10): 3905–3914.
https://doi.org/10.1158/1078-0432.CCR-04-1974
Published: 16 May 2005
View article titled, Characterization of Chemical Constituents in <em>Scutellaria baicalensis</em> with Antiandrogenic and Growth-Inhibitory Activities toward Prostate Carcinoma
Open the PDF for Characterization of Chemical Constituents in <em>Scutellaria baicalensis</em> with Antiandrogenic and Growth-Inhibitory Activities toward Prostate Carcinoma in another window
Includes: Supplementary data