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Bruce J. Dezube
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Journal Articles

Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors

John Sarantopoulos, Geoffrey I. Shapiro, Roger B. Cohen, Jeffrey W. Clark, John S. Kauh, Glen J. Weiss, James M. Cleary, Devalingam Mahalingam, Michael D. Pickard, Hélène M. Faessel, Allison J. Berger, Kristine Burke, George Mulligan, Bruce J. Dezube, R. Donald Harvey
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (4): 847–857.
https://doi.org/10.1158/1078-0432.CCR-15-1338
Published: 14 February 2016
View article titled, Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors
Open the PDF for Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma

Jatin J. Shah, Andrzej J. Jakubowiak, Owen A. O'Connor, Robert Z. Orlowski, R. Donald Harvey, Mitchell R. Smith, Daniel Lebovic, Catherine Diefenbach, Kevin Kelly, Zhaowei Hua, Allison J. Berger, George Mulligan, Hélène M. Faessel, Stephen Tirrell, Bruce J. Dezube, Sagar Lonial
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (1): 34–43.
https://doi.org/10.1158/1078-0432.CCR-15-1237
Published: 03 January 2016
View article titled, Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma
Open the PDF for Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma in another window
Includes: Supplementary data
Journal Articles

First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors

Geoffrey I. Shapiro, Eunice Kwak, Bruce J. Dezube, Murray Yule, John Ayrton, John Lyons, Daruka Mahadevan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (1): 87–97.
https://doi.org/10.1158/1078-0432.CCR-14-0979
Published: 05 January 2015
View article titled, First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors
Open the PDF for First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas

David S. Hong, Razelle Kurzrock, Jeffrey G. Supko, Xiaoying He, Aung Naing, Jennifer Wheler, Donald Lawrence, Joseph Paul Eder, Colin J. Meyer, Deborah A. Ferguson, James Mier, Marina Konopleva, Sergej Konoplev, Michael Andreeff, Donald Kufe, Hillard Lazarus, Geoffrey I. Shapiro, Bruce J. Dezube
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (12): 3396–3406.
https://doi.org/10.1158/1078-0432.CCR-11-2703
Published: 14 June 2012
View article titled, A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas
Open the PDF for A Phase I First-in-Human Trial of Bardoxolone Methyl in Patients with Advanced Solid Tumors and Lymphomas in another window
Includes: Supplementary data
Journal Articles

Phase I Clinical Trial of STA-4783 in Combination with Paclitaxel in Patients with Refractory Solid Tumors

Anna Berkenblit, Joseph P. Eder, Jr., David P. Ryan, Michael V. Seiden, Noriaki Tatsuta, Matthew L. Sherman, Thomas A. Dahl, Bruce J. Dezube, Jeffrey G. Supko
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (2): 584–590.
https://doi.org/10.1158/1078-0432.CCR-06-0964
Published: 25 January 2007
View article titled, Phase I Clinical Trial of STA-4783 in Combination with Paclitaxel in Patients with Refractory Solid Tumors
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Journal Articles

A Phase I Study of Ultra Low Dose Interleukin-2 and Stem Cell Factor in Patients with HIV Infection or HIV and Cancer

Manisha H. Shah, Aharon G. Freud, Don M. Benson, Jr., Amy K. Ferkitich, Bruce J. Dezube, Zale P. Bernstein, Michael A. Caligiuri
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (13): 3993–3996.
https://doi.org/10.1158/1078-0432.CCR-06-0268
Published: 03 July 2006
View article titled, A Phase I Study of Ultra Low Dose Interleukin-2 and Stem Cell Factor in Patients with HIV Infection or HIV and Cancer
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Journal Articles

AIDS-related Kaposi’s Sarcoma: A Phase II Study of Liposomal Doxorubicin

Tony W. Cheung, Scot C. Remick, Nozar Azarnia, Jo Ann Proper, Jose R. Barrueco, Bruce J. Dezube, for the TLC d-99 Study Group
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (11): 3432–3437.
Published: 01 November 1999
View article titled, AIDS-related Kaposi’s Sarcoma: A Phase II Study of Liposomal Doxorubicin
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