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Bristi Basu
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Journal Articles

A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

Susana Banerjee, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle, Florence Raynaud, Ruth Riisnaes, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout, Mona Parmar, Anna Zachariou, Alison Turner, Ben Jenkins, Stuart McIntosh, Ed Ainscow, Anna Minchom, Juanita Lopez, Johann de Bono, Robert Jones, Emma Hall, Natalie Cook, Bristi Basu, Udai Banerji
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (21): 4634–4641.
https://doi.org/10.1158/1078-0432.CCR-22-1268
Published: 01 November 2022
View article titled, A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer

Ayumi Hashimoto, Debashis Sarker, Vikash Reebye, Sheba Jarvis, Mikael H. Sodergren, Andrew Kossenkov, Emilio Sanseviero, Nina Raulf, Jenni Vasara, Pinelopi Andrikakou, Tim Meyer, Kai-Wen Huang, Ruth Plummer, Cheng E. Chee, Duncan Spalding, Madhava Pai, Shahid Khan, David J. Pinato, Rohini Sharma, Bristi Basu, Daniel Palmer, Yuk-Ting Ma, Jeff Evans, Robert Habib, Anna Martirosyan, Naouel Elasri, Adeline Reynaud, John J. Rossi, Mark Cobbold, Nagy A. Habib, Dmitry I. Gabrilovich
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5961–5978.
https://doi.org/10.1158/1078-0432.CCR-21-0986
Published: 01 November 2021
View article titled, Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer
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Journal Articles

MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial

Debashis Sarker, Ruth Plummer, Tim Meyer, Mikael H. Sodergren, Bristi Basu, Cheng Ean Chee, Kai-Wen Huang, Daniel H. Palmer, Yuk Ting Ma, T.R. Jeff Evans, Duncan R.C. Spalding, Madhava Pai, Rohini Sharma, David J. Pinato, James Spicer, Sarah Hunter, Vineet Kwatra, Joanna P. Nicholls, David Collin, Robert Nutbrown, Helen Glenny, Sonia Fairbairn, Vikash Reebye, Jon Voutila, Stephanie Dorman, Pinelopi Andrikakou, Peter Lloyd, Steve Felstead, Jenni Vasara, Robert Habib, Chris Wood, Pal Saetrom, Hans E. Huber, David C. Blakey, John J. Rossi, Nagy Habib
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (15): 3936–3946.
https://doi.org/10.1158/1078-0432.CCR-20-0414
Published: 03 August 2020
View article titled, MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial
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Includes: Supplementary data
Journal Articles

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer

Amit M. Oza, Ursula A. Matulonis, Angeles Alvarez Secord, John Nemunaitis, Lynda D. Roman, Sarah P. Blagden, Susana Banerjee, William P. McGuire, Sharad Ghamande, Michael J. Birrer, Gini F. Fleming, Merry Jennifer Markham, Hal W. Hirte, Diane M. Provencher, Bristi Basu, Rebecca Kristeleit, Deborah K. Armstrong, Benjamin Schwartz, Patricia Braly, Geoff D. Hall, Kenneth P. Nephew, Simone Jueliger, Aram Oganesian, Sue Naim, Yong Hao, Harold Keer, Mohammad Azab, Daniela Matei
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (5): 1009–1016.
https://doi.org/10.1158/1078-0432.CCR-19-1638
Published: 02 March 2020
View article titled, A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer
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Includes: Supplementary data
Journal Articles

First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014

Bristi Basu, Emma Dean, Martina Puglisi, Alastair Greystoke, Michael Ong, Wendy Burke, Maria Cavallin, Graham Bigley, Christopher Womack, Elizabeth A. Harrington, Stephen Green, Elisabeth Oelmann, Johann S. de Bono, Malcolm Ranson, Udai Banerji
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (15): 3412–3419.
https://doi.org/10.1158/1078-0432.CCR-14-2422
Published: 02 August 2015
View article titled, First-in-Human Pharmacokinetic and Pharmacodynamic Study of the Dual m-TORC 1/2 Inhibitor AZD2014
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Includes: Supplementary data
Journal Articles

Combining Antiangiogenics to Overcome Resistance: Rationale and Clinical Experience

Victor Moreno Garcia, Bristi Basu, L. Rhoda Molife, Stan B. Kaye
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (14): 3750–3761.
https://doi.org/10.1158/1078-0432.CCR-11-1275
Published: 15 July 2012
View article titled, Combining Antiangiogenics to Overcome Resistance: Rationale and Clinical Experience
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