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Bob T. Li
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Journal Articles

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention

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Nicolas A. Giraldo, Esther Drill, Baby A. Satravada, Imane El Dika, A. Rose Brannon, Josephine Dermawan, Abhinita Mohanty, Kerem Ozcan, Debyani Chakravarty, Ryma Benayed, Efsevia Vakiani, Ghassan K. Abou-Alfa, Ritika Kundra, Nikolaus Schultz, Bob T. Li, Michael F. Berger, James J. Harding, Marc Ladanyi, Eileen M. O'Reilly, William Jarnagin, Chad Vanderbilt, Olca Basturk, Maria E. Arcila
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5359–5367.
https://doi.org/10.1158/1078-0432.CCR-22-1954
Published: 15 December 2022
View articletitled, Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention
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Includes: Supplementary data
Journal Articles

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

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Jason C. Chang, Michael Offin, Christina Falcon, David Brown, Brian R. Houck-Loomis, Fanli Meng, Vasilisa A. Rudneva, Helen H. Won, Sharon Amir, Joseph Montecalvo, Patrice Desmeules, Kyuichi Kadota, Prasad S. Adusumilli, Valerie W. Rusch, Sarah Teed, Joshua K. Sabari, Ryma Benayed, Khedoudja Nafa, Laetitia Borsu, Bob T. Li, Alison M. Schram, Maria E. Arcila, William D. Travis, Marc Ladanyi, Alexander Drilon, Natasha Rekhtman
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 4066–4076.
https://doi.org/10.1158/1078-0432.CCR-21-0423
Published: 15 July 2021
View articletitled, Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes
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Includes: Supplementary data
Journal Articles

KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma

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Gregory D. Jones, Raul Caso, Kay See Tan, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Yuan Liu, James G. Connolly, Yonina R. Murciano-Goroff, Matthew J. Bott, Prasad S. Adusumilli, Daniela Molena, Gaetano Rocco, Valerie W. Rusch, Smita Sihag, Sandra Misale, Rona Yaeger, Alexander Drilon, Kathryn C. Arbour, Gregory J. Riely, Neal Rosen, Piro Lito, Haiying Zhang, David C. Lyden, Charles M. Rudin, David R. Jones, Bob T. Li, James M. Isbell
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2604–2612.
https://doi.org/10.1158/1078-0432.CCR-20-4772
Published: 01 May 2021
View articletitled, KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

MET Exon 14–altered Lung Cancers and MET Inhibitor Resistance

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Robin Guo, Michael Offin, A. Rose Brannon, Jason Chang, Andrew Chow, Lukas Delasos, Jeffrey Girshman, Olivia Wilkins, Caroline G. McCarthy, Alex Makhnin, Christina Falcon, Kerry Scott, Yuan Tian, Fabiola Cecchi, Todd Hembrough, Deepu Alex, Ronglai Shen, Ryma Benayed, Bob T. Li, Charles M. Rudin, Mark G. Kris, Maria E. Arcila, Natasha Rekhtman, Paul Paik, Ahmet Zehir, Alexander Drilon
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3): 799–806.
https://doi.org/10.1158/1078-0432.CCR-20-2861
Published: 01 February 2021
View articletitled, MET Exon 14–altered Lung Cancers and MET Inhibitor Resistance
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Includes: Supplementary data
Journal Articles

Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion–Positive Lung Cancer by Combining Selpercatinib with Crizotinib

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Ezra Y. Rosen, Melissa L. Johnson, Sarah E. Clifford, Romel Somwar, Jennifer F. Kherani, Jieun Son, Arrien A. Bertram, Monika A. Davare, Eric Gladstone, Elena V. Ivanova, Dahlia N. Henry, Elaine M. Kelley, Mika Lin, Marina S.D. Milan, Binoj C. Nair, Elizabeth A. Olek, Jenna E. Scanlon, Morana Vojnic, Kevin Ebata, Jaclyn F. Hechtman, Bob T. Li, Lynette M. Sholl, Barry S. Taylor, Marc Ladanyi, Pasi A. Jänne, S. Michael Rothenberg, Alexander Drilon, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 34–42.
https://doi.org/10.1158/1078-0432.CCR-20-2278
Published: 04 January 2021
View articletitled, Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion–Positive Lung Cancer by Combining Selpercatinib with Crizotinib
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Includes: Supplementary data
Journal Articles

Abstract 12: Characterizing KRAS G12C and other mutations in plasma ctDNA from patients with lung cancer

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Yonina R. Murciano-Goroff, Emily S. Lebow, Hai-Yan Tu, Mark Li, Lee P. Lim, Kathryn C. Arbour, William Travis, David B. Solit, Marc Ladanyi, David R. Jones, Charles M. Rudin, Andres Martinez, Mackenzie L. Myers, Alexander Makhnin, Pedram Razavi, Michael D. Offin, James W. Isbell, Gregory J. Riely, David M. Hyman, Piro Lito, Bob T. Li
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12_Supplement_1): 12.
https://doi.org/10.1158/1557-3265.ADVPRECMED20-12
Published: 15 June 2020
View articletitled, Abstract 12: Characterizing KRAS G12C and other mutations in plasma ctDNA from patients with lung cancer
Journal Articles

Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC

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Matthew D. Hellmann, Barzin Y. Nabet, Hira Rizvi, Aadel A. Chaudhuri, Daniel K. Wells, Mark P.S. Dunphy, Jacob J. Chabon, Chih Long Liu, Angela B. Hui, Kathryn C. Arbour, Jia Luo, Isabel R. Preeshagul, Everett J. Moding, Diego Almanza, Rene F. Bonilla, Jennifer L. Sauter, Hyejin Choi, Megan Tenet, Mohsen Abu-Akeel, Andrew J. Plodkowski, Rocio Perez Johnston, Christopher H. Yoo, Ryan B. Ko, Henning Stehr, Linda Gojenola, Heather A. Wakelee, Sukhmani K. Padda, Joel W. Neal, Jamie E. Chaft, Mark G. Kris, Charles M. Rudin, Taha Merghoub, Bob T. Li, Ash A. Alizadeh, Maximilian Diehn
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12): 2849–2858.
https://doi.org/10.1158/1078-0432.CCR-19-3418
Published: 15 June 2020
View articletitled, Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
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Includes: Supplementary data
Journal Articles

Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling

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A. Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Yu Hu, Anna Razumova, Fanli Meng, Emily Lebow, Juber Patel, Ian Johnson, Preethi Srinivasan, Maysun Hasan, Jenna-marie Dix, Aijazuddin Syed, Brian Houck-Loomis, Bob T. Li, Charles Rudin, David Solit, Marc Ladanyi, Maria Arcila, Dana Tsui, Ahmet Zehir, Michael Berger, Ryma Benayed
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): PR08.
https://doi.org/10.1158/1557-3265.LiqBiop20-PR08
Published: 01 June 2020
View articletitled, Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling
Journal Articles

Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations

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Siddhartha Devarakonda, Sumithra Sankararaman, Brett H. Herzog, Kathryn A. Gold, Saiama N. Waqar, Jeffrey P. Ward, Victoria M. Raymond, Richard B. Lanman, Aadel A. Chaudhuri, Taofeek K. Owonikoko, Bob T. Li, John T. Poirier, Charles M. Rudin, Ramaswamy Govindan, Daniel Morgensztern
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (20): 6119–6126.
https://doi.org/10.1158/1078-0432.CCR-19-0879
Published: 15 October 2019
View articletitled, Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations
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Includes: Supplementary data
Journal Articles

Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas

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Philip Jonsson, Andrew L. Lin, Robert J. Young, Natalie M. DiStefano, David M. Hyman, Bob T. Li, Michael F. Berger, Ahmet Zehir, Marc Ladanyi, David B. Solit, Angela G. Arnold, Zsofia K. Stadler, Diana Mandelker, Michael E. Goldberg, Juliann Chmielecki, Maryam Pourmaleki, Shahiba Q. Ogilvie, Shweta S. Chavan, Andrew T. McKeown, Malbora Manne, Allison Hyde, Kathryn Beal, T. Jonathan Yang, Craig P. Nolan, Elena Pentsova, Antonio Omuro, Igor T. Gavrilovic, Thomas J. Kaley, Eli L. Diamond, Jacqueline B. Stone, Christian Grommes, Adrienne Boire, Mariza Daras, Anna F. Piotrowski, Alexandra M. Miller, Philip H. Gutin, Timothy A. Chan, Viviane S. Tabar, Cameron W. Brennan, Marc Rosenblum, Lisa M. DeAngelis, Ingo K. Mellinghoff, Barry S. Taylor
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (18): 5537–5547.
https://doi.org/10.1158/1078-0432.CCR-19-0032
Published: 13 September 2019
View articletitled, Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas
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Includes: Supplementary data
Journal Articles

Phase I Study of Intermittent High-Dose Lapatinib Alternating with Capecitabine for HER2-Positive Breast Cancer Patients with Central Nervous System Metastases

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Aki Morikawa, Elisa de Stanchina, Elena Pentsova, Margaret M. Kemeny, Bob T. Li, Kendrick Tang, Sujata Patil, Martin Fleisher, Catherine Van Poznak, Larry Norton, Andrew D. Seidman
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3784–3792.
https://doi.org/10.1158/1078-0432.CCR-18-3502
Published: 01 July 2019
View articletitled, Phase I Study of Intermittent High-Dose Lapatinib Alternating with Capecitabine for HER2-Positive Breast Cancer Patients with Central Nervous System Metastases
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Includes: Supplementary data
Journal Articles

Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers

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Michael Offin, Hira Rizvi, Megan Tenet, Andy Ni, Francisco Sanchez-Vega, Bob T. Li, Alexander Drilon, Mark G. Kris, Charles M. Rudin, Nikolaus Schultz, Maria E. Arcila, Marc Ladanyi, Gregory J. Riely, Helena Yu, Matthew D. Hellmann
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (3): 1063–1069.
https://doi.org/10.1158/1078-0432.CCR-18-1102
Published: 01 February 2019
View articletitled, Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers
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Includes: Supplementary data
Journal Articles

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer

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Tara E. Soumerai, Mark T.A. Donoghue, Chaitanya Bandlamudi, Preethi Srinivasan, Matthew T. Chang, Dmitriy Zamarin, Karen A. Cadoo, Rachel N. Grisham, Roisin E. O'Cearbhaill, William P. Tew, Jason A. Konner, Martee L. Hensley, Vicky Makker, Paul Sabbatini, David R. Spriggs, Tiffany A. Troso-Sandoval, Alexandra Snyder Charen, Claire Friedman, Mila Gorsky, Sarah J. Schweber, Sumit Middha, Rajmohan Murali, Sarah Chiang, Kay J. Park, Robert A. Soslow, Marc Ladanyi, Bob T. Li, Jennifer Mueller, Britta Weigelt, Ahmet Zehir, Michael F. Berger, Nadeem R. Abu-Rustum, Carol Aghajanian, Deborah F. DeLair, David B. Solit, Barry S. Taylor, David M. Hyman
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (23): 5939–5947.
https://doi.org/10.1158/1078-0432.CCR-18-0412
Published: 03 December 2018
View articletitled, Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer
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Includes: Supplementary data
Journal Articles

Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance

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Helena A. Yu, Ken Suzawa, Emmet Jordan, Ahmet Zehir, Ai Ni, Ryan Kim, Mark G. Kris, Matthew D. Hellmann, Bob T. Li, Romel Somwar, David B. Solit, Michael F. Berger, Maria Arcila, Gregory J. Riely, Marc Ladanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (13): 3108–3118.
https://doi.org/10.1158/1078-0432.CCR-17-2961
Published: 01 July 2018
View articletitled, Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance
Open the PDF for Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance in another window
Includes: Supplementary data