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Beow Y. Yeap
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Journal Articles

Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas

Jennifer Y. Wo, Jeffrey W. Clark, Christine E. Eyler, Mari Mino-Kenudson, Samuel J. Klempner, Jill N. Allen, Florence K. Keane, Aparna R. Parikh, Eric Roeland, Lorraine C. Drapek, David P. Ryan, Ryan B. Corcoran, Emily Van Seventer, Isobel J. Fetter, Heather A. Shahzade, Melin J. Khandekar, Michael Lanuti, Christopher R. Morse, Rebecca S. Heist, Christine A. Ulysse, Benjamin Christopher, Christian Baglini, Beow Y. Yeap, John T. Mullen, Theodore S. Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6343–6353.
https://doi.org/10.1158/1078-0432.CCR-21-0331
Published: 01 December 2021
View article titled, Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas
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Includes: Supplementary data
Journal Articles

Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion–Positive Lung Cancer

Jessica J. Lin, Noura J. Choudhury, Satoshi Yoda, Viola W. Zhu, Ted W. Johnson, Ramin Sakhtemani, Ibiayi Dagogo-Jack, Subba R. Digumarthy, Charlotte Lee, Andrew Do, Jennifer Peterson, Kylie Prutisto-Chang, Wafa Malik, Harper G. Hubbeling, Adam Langenbucher, Adam J. Schoenfeld, Christina J. Falcon, Jennifer S. Temel, Lecia V. Sequist, Beow Y. Yeap, Jochen K. Lennerz, Alice T. Shaw, Michael S. Lawrence, Sai-Hong Ignatius Ou, Aaron N. Hata, Alexander Drilon, Justin F. Gainor
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2899–2909.
https://doi.org/10.1158/1078-0432.CCR-21-0032
Published: 15 May 2021
View article titled, Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in <em>ROS1</em> Fusion–Positive Lung Cancer
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Includes: Supplementary data
Journal Articles

MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer

Ibiayi Dagogo-Jack, Satoshi Yoda, Jochen K. Lennerz, Adam Langenbucher, Jessica J. Lin, Marguerite M. Rooney, Kylie Prutisto-Chang, Audris Oh, Nathaniel A. Adams, Beow Y. Yeap, Emily Chin, Andrew Do, Hetal D. Marble, Sara E. Stevens, Subba R. Digumarthy, Ashish Saxena, Rebecca J. Nagy, Cyril H. Benes, Christopher G. Azzoli, Michael S. Lawrence, Justin F. Gainor, Alice T. Shaw, Aaron N. Hata
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (11): 2535–2545.
https://doi.org/10.1158/1078-0432.CCR-19-3906
Published: 01 June 2020
View article titled, MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer
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Includes: Supplementary data
Journal Articles

Treatment with Next-Generation ALK Inhibitors Fuels Plasma ALK Mutation Diversity

Ibiayi Dagogo-Jack, Marguerite Rooney, Jessica J. Lin, Rebecca J. Nagy, Beow Y. Yeap, Harper Hubbeling, Emily Chin, Jennifer Ackil, Anna F. Farago, Aaron N. Hata, Jochen K. Lennerz, Justin F. Gainor, Richard B. Lanman, Alice T. Shaw
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (22): 6662–6670.
https://doi.org/10.1158/1078-0432.CCR-19-1436
Published: 15 November 2019
View article titled, Treatment with Next-Generation ALK Inhibitors Fuels Plasma <em>ALK</em> Mutation Diversity
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Includes: Supplementary data
Journal Articles

Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-mutant Lung Cancer

Ibiayi Dagogo-Jack, Pablo Martinez, Beow Y. Yeap, Chiara Ambrogio, Lorin A. Ferris, Christine Lydon, Tom Nguyen, Nicholas A. Jessop, A. John Iafrate, Bruce E. Johnson, Jochen K. Lennerz, Alice T. Shaw, Mark M. Awad
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 158–165.
https://doi.org/10.1158/1078-0432.CCR-18-2062
Published: 03 January 2019
View article titled, Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-mutant Lung Cancer
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Includes: Supplementary data
Journal Articles

EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non–Small Cell Lung Cancer: A Retrospective Analysis

Justin F. Gainor, Alice T. Shaw, Lecia V. Sequist, Xiujun Fu, Christopher G. Azzoli, Zofia Piotrowska, Tiffany G. Huynh, Ling Zhao, Linnea Fulton, Katherine R. Schultz, Emily Howe, Anna F. Farago, Ryan J. Sullivan, James R. Stone, Subba Digumarthy, Teresa Moran, Aaron N. Hata, Yukako Yagi, Beow Y. Yeap, Jeffrey A. Engelman, Mari Mino-Kenudson
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (18): 4585–4593.
https://doi.org/10.1158/1078-0432.CCR-15-3101
Published: 15 September 2016
View article titled, <em>EGFR</em> Mutations and <em>ALK</em> Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non–Small Cell Lung Cancer: A Retrospective Analysis
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Includes: Supplementary data
Journal Articles

Progression-Free and Overall Survival in ALK-Positive NSCLC Patients Treated with Sequential Crizotinib and Ceritinib

Justin F. Gainor, Daniel S.W. Tan, Tomasso De Pas, Benjamin J. Solomon, Aziah Ahmad, Chiara Lazzari, Filippo de Marinis, Gianluca Spitaleri, Katherine Schultz, Luc Friboulet, Beow Y. Yeap, Jeffrey A. Engelman, Alice T. Shaw
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (12): 2745–2752.
https://doi.org/10.1158/1078-0432.CCR-14-3009
Published: 14 June 2015
View article titled, Progression-Free and Overall Survival in ALK-Positive NSCLC Patients Treated with Sequential Crizotinib and Ceritinib
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Includes: Supplementary data
Journal Articles

Clinical, Pathologic, and Biologic Features Associated with BRAF Mutations in Non–Small Cell Lung Cancer

Stephanie Cardarella, Atsuko Ogino, Mizuki Nishino, Mohit Butaney, Jeanne Shen, Christine Lydon, Beow Y. Yeap, Lynette M. Sholl, Bruce E. Johnson, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4532–4540.
https://doi.org/10.1158/1078-0432.CCR-13-0657
Published: 13 August 2013
View article titled, Clinical, Pathologic, and Biologic Features Associated with <em>BRAF</em> Mutations in Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer

Justin F. Gainor, Anna M. Varghese, Sai-Hong Ignatius Ou, Sheheryar Kabraji, Mark M. Awad, Ryohei Katayama, Amanda Pawlak, Mari Mino-Kenudson, Beow Y. Yeap, Gregory J. Riely, A. John Iafrate, Maria E. Arcila, Marc Ladanyi, Jeffrey A. Engelman, Dora Dias-Santagata, Alice T. Shaw
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (15): 4273–4281.
https://doi.org/10.1158/1078-0432.CCR-13-0318
Published: 31 July 2013
View article titled, <em>ALK</em> Rearrangements Are Mutually Exclusive with Mutations in <em>EGFR</em> or <em>KRAS</em>: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer
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Journal Articles

Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma

Assunta De Rienzo, William G. Richards, Beow Y. Yeap, Melissa H. Coleman, Peter E. Sugarbaker, Lucian R. Chirieac, Yaoyu E. Wang, John Quackenbush, Roderick V. Jensen, Raphael Bueno
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (9): 2493–2502.
https://doi.org/10.1158/1078-0432.CCR-12-2117
Published: 30 April 2013
View article titled, Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma
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Includes: Supplementary data
Journal Articles

The Impact of Initial Gefitinib or Erlotinib versus Chemotherapy on Central Nervous System Progression in Advanced Non–Small Cell Lung Cancer with EGFR Mutations

Stephanie Heon, Beow Y. Yeap, Neal I. Lindeman, Victoria A. Joshi, Mohit Butaney, Gregory J. Britt, Daniel B. Costa, Michael S. Rabin, David M. Jackman, Bruce E. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (16): 4406–4414.
https://doi.org/10.1158/1078-0432.CCR-12-0357
Published: 14 August 2012
View article titled, The Impact of Initial Gefitinib or Erlotinib versus Chemotherapy on Central Nervous System Progression in Advanced Non–Small Cell Lung Cancer with <em>EGFR</em> Mutations
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Journal Articles

Activation of PI3K Signaling in Merkel Cell Carcinoma

Valentina Nardi, Youngchul Song, Juan A. Santamaria-Barria, Arjola K. Cosper, Quynh Lam, Anthony C. Faber, Genevieve M. Boland, Beow Y. Yeap, Kristin Bergethon, Vanessa L. Scialabba, Hensin Tsao, Jeffrey Settleman, David P. Ryan, Darrell R. Borger, Atul K. Bhan, Mai P. Hoang, Anthony J. Iafrate, James C. Cusack, Jeffrey A. Engelman, Dora Dias-Santagata
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (5): 1227–1236.
https://doi.org/10.1158/1078-0432.CCR-11-2308
Published: 01 March 2012
View article titled, Activation of PI3K Signaling in Merkel Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Fine-Needle Aspiration Biopsies for Gene Expression Ratio-Based Diagnostic and Prognostic Tests in Malignant Pleural Mesothelioma

Assunta De Rienzo, Lingsheng Dong, Beow Y. Yeap, Roderick V. Jensen, William G. Richards, Gavin J. Gordon, David J. Sugarbaker, Raphael Bueno
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (2): 310–316.
https://doi.org/10.1158/1078-0432.CCR-10-0806
Published: 16 January 2011
View article titled, Fine-Needle Aspiration Biopsies for Gene Expression Ratio-Based Diagnostic and Prognostic Tests in Malignant Pleural Mesothelioma
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Journal Articles

Development of Central Nervous System Metastases in Patients with Advanced Non–Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib or Erlotinib

Stephanie Heon, Beow Y. Yeap, Gregory J. Britt, Daniel B. Costa, Michael S. Rabin, David M. Jackman, Bruce E. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (23): 5873–5882.
https://doi.org/10.1158/1078-0432.CCR-10-1588
Published: 06 December 2010
View article titled, Development of Central Nervous System Metastases in Patients with Advanced Non–Small Cell Lung Cancer and Somatic <em>EGFR</em> Mutations Treated with Gefitinib or Erlotinib
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Journal Articles

Unique Clinicopathologic Features Characterize ALK-Rearranged Lung Adenocarcinoma in the Western Population

Scott J. Rodig, Mari Mino-Kenudson, Sanja Dacic, Beow Y. Yeap, Alice Shaw, Justine A. Barletta, Hannah Stubbs, Kenny Law, Neal Lindeman, Eugene Mark, Pasi A. Janne, Thomas Lynch, Bruce E. Johnson, A. John Iafrate, Lucian R. Chirieac
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (16): 5216–5223.
https://doi.org/10.1158/1078-0432.CCR-09-0802
Published: 12 August 2009
View article titled, Unique Clinicopathologic Features Characterize <em>ALK</em>-Rearranged Lung Adenocarcinoma in the Western Population
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Includes: Supplementary data
Journal Articles

Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an Online Tumor Registry of Clinical Trials

David M. Jackman, Vincent A. Miller, Leigh-Anne Cioffredi, Beow Y. Yeap, Pasi A. Jänne, Gregory J. Riely, Marielle Gallegos Ruiz, Giuseppe Giaccone, Lecia V. Sequist, Bruce E. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (16): 5267–5273.
https://doi.org/10.1158/1078-0432.CCR-09-0888
Published: 12 August 2009
View article titled, Impact of Epidermal Growth Factor Receptor and <em>KRAS</em> Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an Online Tumor Registry of Clinical Trials
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Journal Articles

Noninvasive Detection of EGFR T790M in Gefitinib or Erlotinib Resistant Non–Small Cell Lung Cancer

Yanan Kuang, Andrew Rogers, Beow Y. Yeap, Lilin Wang, Mike Makrigiorgos, Kristi Vetrand, Sara Thiede, Robert J. Distel, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (8): 2630–2636.
https://doi.org/10.1158/1078-0432.CCR-08-2592
Published: 15 April 2009
View article titled, Noninvasive Detection of <em>EGFR</em> T790M in Gefitinib or Erlotinib Resistant Non–Small Cell Lung Cancer
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Journal Articles

Effects of Erlotinib in EGFR Mutated Non-Small Cell Lung Cancers with Resistance to Gefitinib

Daniel B. Costa, Kim-Son H. Nguyen, Byoung C. Cho, Lecia V. Sequist, David M. Jackman, Gregory J. Riely, Beow Y. Yeap, Balázs Halmos, Joo H. Kim, Pasi A. Jänne, Mark S. Huberman, William Pao, Daniel G. Tenen, Susumu Kobayashi
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (21): 7060–7067.
https://doi.org/10.1158/1078-0432.CCR-08-1455
Published: 03 November 2008
View article titled, Effects of Erlotinib in <em>EGFR</em> Mutated Non-Small Cell Lung Cancers with Resistance to Gefitinib
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Journal Articles

Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib

David M. Jackman, Beow Y. Yeap, Lecia V. Sequist, Neal Lindeman, Alison J. Holmes, Victoria A. Joshi, Daphne W. Bell, Mark S. Huberman, Balazs Halmos, Michael S. Rabin, Daniel A. Haber, Thomas J. Lynch, Matthew Meyerson, Bruce E. Johnson, Pasi A. Jänne
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (13): 3908–3914.
https://doi.org/10.1158/1078-0432.CCR-06-0462
Published: 03 July 2006
View article titled, Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib
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Journal Articles

Validation of Genomics-Based Prognostic Tests in Malignant Pleural Mesothelioma

Gavin J. Gordon, Graham N. Rockwell, Paul A. Godfrey, Roderick V. Jensen, Jonathan N. Glickman, Beow Y. Yeap, William G. Richards, David J. Sugarbaker, Raphael Bueno
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (12): 4406–4414.
https://doi.org/10.1158/1078-0432.CCR-04-2181
Published: 15 June 2005
View article titled, Validation of Genomics-Based Prognostic Tests in Malignant Pleural Mesothelioma
Open the PDF for Validation of Genomics-Based Prognostic Tests in Malignant Pleural Mesothelioma in another window
Includes: Supplementary data