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Bartosz Chmielowski
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Journal Articles

Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial

David S. Hong, Michael Postow, Bartosz Chmielowski, Ryan Sullivan, Amita Patnaik, Ezra E.W. Cohen, Geoffrey Shapiro, Conor Steuer, Martin Gutierrez, Heather Yeckes-Rodin, Robert Ilaria, Jr, Brenda O'Connell, Joanna Peng, Guangbin Peng, Nora Zizlsperger, Anthony Tolcher, Jedd D. Wolchok
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (12): 2210–2219.
https://doi.org/10.1158/1078-0432.CCR-22-3313
Published: 13 June 2023
View article titled, Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial
Open the PDF for Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial in another window
Includes: Supplementary data
Journal Articles

Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy

Zev A. Wainberg, Arun S. Singh, Gottfried E. Konecny, Kelly E. McCann, J. Randolph Hecht, Jonathan Goldman, Bartosz Chmielowski, Richard S. Finn, Neil O'Brien, Erika Von Euw, Megan M. Price, Diego Martinez, Lisa Yonemoto, Meghan Brennan, John A. Glaspy, Dennis J. Slamon
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 40–49.
https://doi.org/10.1158/1078-0432.CCR-22-1553
Published: 04 January 2023
View article titled, Preclinical and Clinical Trial Results Using Talazoparib and Low-Dose Chemotherapy
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Includes: Supplementary data
Journal Articles

Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT

William D. Tap, Arun S. Singh, Stephen Patrick Anthony, Mike Sterba, Chao Zhang, John H. Healey, Bartosz Chmielowski, Allen Lee Cohn, Geoffrey I. Shapiro, Vicki L. Keedy, Zev A. Wainberg, Igor Puzanov, Gregory M. Cote, Andrew J. Wagner, Fadi Braiteh, Eric Sherman, Henry H. Hsu, Charles Peterfy, Heather L. Gelhorn, Xin Ye, Paul Severson, Brian L. West, Paul S. Lin, Sandra Tong-Starksen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 298–307.
https://doi.org/10.1158/1078-0432.CCR-21-2007
Published: 15 January 2022
View article titled, Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT
Open the PDF for Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT in another window
Includes: Supplementary data
Journal Articles

A Randomized Phase II Study of Nivolumab Monotherapy or Nivolumab Combined with Ipilimumab in Patients with Advanced Gastrointestinal Stromal Tumors

Arun S. Singh, J. Randolph Hecht, Lee Rosen, Zev A. Wainberg, Xiaoyan Wang, Michael Douek, Anahis Hagopian, Rachel Andes, Lauren Sauer, Sandra R. Brackert, Warren Chow, Ronald DeMatteo, Fritz Christian Eilber, John A. Glaspy, Bartosz Chmielowski
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 84–94.
https://doi.org/10.1158/1078-0432.CCR-21-0878
Published: 05 January 2022
View article titled, A Randomized Phase II Study of Nivolumab Monotherapy or Nivolumab Combined with Ipilimumab in Patients with Advanced Gastrointestinal Stromal Tumors
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Journal Articles

A Phase II Trial of 5-Day Neoadjuvant Radiotherapy for Patients with High-Risk Primary Soft Tissue Sarcoma

Anusha Kalbasi, Mitchell Kamrava, Fang-I Chu, Donatello Telesca, Ritchell Van Dams, Yingli Yang, Dan Ruan, Scott D. Nelson, Sarah M. Dry, Jackie Hernandez, Bartosz Chmielowski, Arun S. Singh, Susan V. Bukata, Nicholas M. Bernthal, Michael L. Steinberg, Joanne B. Weidhaas, Fritz C. Eilber
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1829–1836.
https://doi.org/10.1158/1078-0432.CCR-19-3524
Published: 15 April 2020
View article titled, A Phase II Trial of 5-Day Neoadjuvant Radiotherapy for Patients with High-Risk Primary Soft Tissue Sarcoma
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Includes: Supplementary data
Journal Articles

A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab

Theodore S. Nowicki, Beata Berent-Maoz, Gardenia Cheung-Lau, Rong Rong Huang, Xiaoyan Wang, Jennifer Tsoi, Paula Kaplan-Lefko, Paula Cabrera, Justin Tran, Jia Pang, Mignonette Macabali, Ivan Perez Garcilazo, Ignacio Baselga Carretero, Anusha Kalbasi, Alistair J. Cochran, Catherine S. Grasso, Siwen Hu-Lieskovan, Bartosz Chmielowski, Begoña Comin-Anduix, Arun Singh, Antoni Ribas
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (7): 2096–2108.
https://doi.org/10.1158/1078-0432.CCR-18-3496
Published: 01 April 2019
View article titled, A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab
Open the PDF for A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab in another window
Includes: Supplementary data
Journal Articles

Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma

Thinle Chodon, Begoña Comin-Anduix, Bartosz Chmielowski, Richard C. Koya, Zhongqi Wu, Martin Auerbach, Charles Ng, Earl Avramis, Elizabeth Seja, Arturo Villanueva, Tara A. McCannel, Akira Ishiyama, Johannes Czernin, Caius G. Radu, Xiaoyan Wang, David W. Gjertson, Alistair J. Cochran, Kenneth Cornetta, Deborah J.L. Wong, Paula Kaplan-Lefko, Omid Hamid, Wolfram Samlowski, Peter A. Cohen, Gregory A. Daniels, Bijay Mukherji, Lili Yang, Jerome A. Zack, Donald B. Kohn, James R. Heath, John A. Glaspy, Owen N. Witte, David Baltimore, James S. Economou, Antoni Ribas
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2457–2465.
https://doi.org/10.1158/1078-0432.CCR-13-3017
Published: 30 April 2014
View article titled, Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma
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Includes: Supplementary data
Journal Articles

CTLA4 Blockade Induces Frequent Tumor Infiltration by Activated Lymphocytes Regardless of Clinical Responses in Humans

Rong Rong Huang, Jason Jalil, James S. Economou, Bartosz Chmielowski, Richard C. Koya, Stephen Mok, Hooman Sazegar, Elizabeth Seja, Arturo Villanueva, Jesus Gomez-Navarro, John A. Glaspy, Alistair J. Cochran, Antoni Ribas
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 4101–4109.
https://doi.org/10.1158/1078-0432.CCR-11-0407
Published: 15 June 2011
View article titled, CTLA4 Blockade Induces Frequent Tumor Infiltration by Activated Lymphocytes Regardless of Clinical Responses in Humans
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Includes: Supplementary data
Journal Articles

Intra–Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial

Antoni Ribas, Jeffrey S. Weber, Bartosz Chmielowski, Begonya Comin-Anduix, David Lu, Michael Douek, Nagesh Ragavendra, Steve Raman, Elizabeth Seja, Darlene Rosario, Sabrina Miles, David C. Diamond, Zhiyong Qiu, Mihail Obrocea, Adrian Bot
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (9): 2987–2996.
https://doi.org/10.1158/1078-0432.CCR-10-3272
Published: 01 May 2011
View article titled, Intra–Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial
Open the PDF for Intra–Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial in another window
Includes: Supplementary data
Journal Articles

The Oncogenic BRAF Kinase Inhibitor PLX4032/RG7204 Does Not Affect the Viability or Function of Human Lymphocytes across a Wide Range of Concentrations

Begoña Comin-Anduix, Thinle Chodon, Hooman Sazegar, Douglas Matsunaga, Stephen Mock, Jason Jalil, Helena Escuin-Ordinas, Bartosz Chmielowski, Richard C Koya, Antoni Ribas
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (24): 6040–6048.
https://doi.org/10.1158/1078-0432.CCR-10-1911
Published: 16 December 2010
View article titled, The Oncogenic BRAF Kinase Inhibitor PLX4032/RG7204 Does Not Affect the Viability or Function of Human Lymphocytes across a Wide Range of Concentrations
Open the PDF for The Oncogenic BRAF Kinase Inhibitor PLX4032/RG7204 Does Not Affect the Viability or Function of Human Lymphocytes across a Wide Range of Concentrations in another window
Includes: Supplementary data
Journal Articles

Do We Need a Different Set of Response Assessment Criteria for Tumor Immunotherapy?

Antoni Ribas, Bartosz Chmielowski, John A. Glaspy
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7116–7118.
https://doi.org/10.1158/1078-0432.CCR-09-2376
Published: 30 November 2009
View article titled, Do We Need a Different Set of Response Assessment Criteria for Tumor Immunotherapy?
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Includes: Supplementary data
Journal Articles

Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma

Antoni Ribas, Begoña Comin-Anduix, Bartosz Chmielowski, Jason Jalil, Pilar de la Rocha, Tara A. McCannel, Maria Teresa Ochoa, Elizabeth Seja, Arturo Villanueva, Denise K. Oseguera, Bradley R. Straatsma, Alistair J. Cochran, John A. Glaspy, Liu Hui, Francesco M. Marincola, Ena Wang, James S. Economou, Jesus Gomez-Navarro
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6267–6276.
https://doi.org/10.1158/1078-0432.CCR-09-1254
Published: 30 September 2009
View article titled, Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma
Open the PDF for Dendritic Cell Vaccination Combined with CTLA4 Blockade in Patients with Metastatic Melanoma in another window
Includes: Supplementary data