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B. Nebiyou Bekele
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Journal Articles

Combined MEK and VEGFR Inhibition in Orthotopic Human Lung Cancer Models Results in Enhanced Inhibition of Tumor Angiogenesis, Growth, and Metastasis

Osamu Takahashi, Ritsuko Komaki, Paul D. Smith, Juliane M. Jürgensmeier, Anderson Ryan, B. Nebiyou Bekele, Ignacio I. Wistuba, Jörg J. Jacoby, Maria V. Korshunova, Anna Biernacka, Baruch Erez, Keiko Hosho, Roy S. Herbst, Michael S. O'Reilly
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (6): 1641–1654.
https://doi.org/10.1158/1078-0432.CCR-11-2324
Published: 14 March 2012
View article titled, Combined MEK and VEGFR Inhibition in Orthotopic Human Lung Cancer Models Results in Enhanced Inhibition of Tumor Angiogenesis, Growth, and Metastasis
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Journal Articles

Myeloid Biomarkers Associated with Glioblastoma Response to Anti-VEGF Therapy with Aflibercept

John F. de Groot, Yuji Piao, Hai Tran, Mark Gilbert, Hua-Kang Wu, Jun Liu, B. Nebiyou Bekele, Tim Cloughesy, Minesh Mehta, H. Ian Robins, Andrew Lassman, Lisa DeAngelis, Kevin Camphausen, Alice Chen, WKA Yung, Michael Prados, Patrick Y. Wen, John V. Heymach
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4872–4881.
https://doi.org/10.1158/1078-0432.CCR-11-0271
Published: 17 July 2011
View article titled, Myeloid Biomarkers Associated with Glioblastoma Response to Anti-VEGF Therapy with Aflibercept
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Includes: Supplementary data
Journal Articles

Nrf2 and Keap1 Abnormalities in Non–Small Cell Lung Carcinoma and Association with Clinicopathologic Features

Luisa M. Solis, Carmen Behrens, Wenli Dong, Milind Suraokar, Natalie C. Ozburn, Cesar A. Moran, Alejandro H. Corvalan, Shyam Biswal, Stephen G. Swisher, B. Nebiyou Bekele, John D. Minna, David J. Stewart, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14): 3743–3753.
https://doi.org/10.1158/1078-0432.CCR-09-3352
Published: 14 July 2010
View article titled, Nrf2 and Keap1 Abnormalities in Non–Small Cell Lung Carcinoma and Association with Clinicopathologic Features
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Includes: Supplementary data
Journal Articles

Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non–Small Cell Lung Cancer

Jennifer M. Brannan, Wenli Dong, Ludmila Prudkin, Carmen Behrens, Reuben Lotan, B. Nebiyou Bekele, Ignacio Wistuba, Faye M. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (13): 4423–4430.
https://doi.org/10.1158/1078-0432.CCR-09-0473
Published: 01 July 2009
View article titled, Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non–Small Cell Lung Cancer
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Journal Articles

Elevated Phospho-S6 Expression Is Associated with Metastasis in Adenocarcinoma of the Lung

J. Matthew McDonald, Christopher E. Pelloski, Alicia Ledoux, Menghong Sun, Gabriela Raso, Ritsuko Komaki, Ignacio I. Wistuba, B. Nebiyou Bekele, Ken Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7832–7837.
https://doi.org/10.1158/1078-0432.CCR-08-0565
Published: 01 December 2008
View article titled, Elevated Phospho-S6 Expression Is Associated with Metastasis in Adenocarcinoma of the Lung
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Journal Articles

Loss and Reduction of Fus1 Protein Expression is a Frequent Phenomenon in the Pathogenesis of Lung Cancer

Ludmila Prudkin, Carmen Behrens, Diane D. Liu, Xian Zhou, Natalie C. Ozburn, B. Nebiyou Bekele, John D. Minna, Cesar Moran, Jack A. Roth, Lin Ji, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (1): 41–47.
https://doi.org/10.1158/1078-0432.CCR-07-1252
Published: 02 January 2008
View article titled, Loss and Reduction of Fus1 Protein Expression is a Frequent Phenomenon in the Pathogenesis of Lung Cancer
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Includes: Supplementary data
Journal Articles

Cetuximab and Irinotecan Interact Synergistically to Inhibit the Growth of Orthotopic Anaplastic Thyroid Carcinoma Xenografts in Nude Mice

Seungwon Kim, Christopher N. Prichard, Maher N. Younes, Yasemin D. Yazici, Samar A. Jasser, B. Nebiyou Bekele, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 600–607.
https://doi.org/10.1158/1078-0432.CCR-05-1325
Published: 20 January 2006
View article titled, Cetuximab and Irinotecan Interact Synergistically to Inhibit the Growth of Orthotopic Anaplastic Thyroid Carcinoma Xenografts in Nude Mice
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Journal Articles

Delta-24 Increases the Expression and Activity of Topoisomerase I and Enhances the Antiglioma Effect of Irinotecan

Candelaria Gomez-Manzano, Marta M. Alonso, W.K. Alfred Yung, Frank McCormick, David T. Curiel, Frederick F. Lang, Hong Jiang, B. Nebiyou Bekele, Xian Zhou, Ramon Alemany, Juan Fueyo
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 556–562.
https://doi.org/10.1158/1078-0432.CCR-05-1892
Published: 20 January 2006
View article titled, Delta-24 Increases the Expression and Activity of Topoisomerase I and Enhances the Antiglioma Effect of Irinotecan
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Journal Articles

Aberrant Promoter Hypermethylation of Multiple Genes in Gallbladder Carcinoma and Chronic Cholecystitis

Takao Takahashi, Narayan Shivapurkar, Erick Riquelme, Hisayuki Shigematsu, Jyotsna Reddy, Makoto Suzuki, Kuniharu Miyajima, Xian Zhou, B. Nebiyou Bekele, Adi F. Gazdar, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 6126–6133.
https://doi.org/10.1158/1078-0432.CCR-04-0579
Published: 24 September 2004
View article titled, Aberrant Promoter Hypermethylation of Multiple Genes in Gallbladder Carcinoma and Chronic Cholecystitis
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Journal Articles

Aberrant Promoter Methylation and Silencing of Laminin-5-Encoding Genes in Breast Carcinoma

Ubaradka G. Sathyanarayana, Asha Padar, Chun Xian Huang, Makoto Suzuki, Hisayuki Shigematsu, B. Nebiyou Bekele, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6389–6394.
Published: 24 December 2003
View article titled, Aberrant Promoter Methylation and Silencing of Laminin-5-Encoding Genes in Breast Carcinoma
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Journal Articles

A Phase I/IIA Trial of Continuous Five-Day Infusion of Squalamine Lactate (MSI-1256F) Plus Carboplatin and Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer

Roy S. Herbst, Lisa A. Hammond, David P. Carbone, Hai T. Tran, Kenneth J. Holroyd, Avinash Desai, Jon I. Williams, B. Nebiyou Bekele, Howard Hait, Victoria Allgood, Stephen Solomon, Joan H. Schiller
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (11): 4108–4115.
Published: 30 September 2003
View article titled, A Phase I/IIA Trial of Continuous Five-Day Infusion of Squalamine Lactate (MSI-1256F) Plus Carboplatin and Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer
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Journal Articles

Epidermal Growth Factor Receptor Blockade Potentiates Apoptosis Mediated by Paclitaxel and Leads to Prolonged Survival in a Murine Model of Oral Cancer

F. Christopher Holsinger, Dao D. Doan, Samar A. Jasser, Eric A. Swan, Jayson S. Greenberg, Bradley A. Schiff, B. Nebiyou Bekele, Maher N. Younes, Corazon D. Bucana, Isaiah J. Fidler, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (8): 3183–3189.
Published: 11 August 2003
View article titled, Epidermal Growth Factor Receptor Blockade Potentiates Apoptosis Mediated by Paclitaxel and Leads to Prolonged Survival in a Murine Model of Oral Cancer
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Journal Articles

An Orthotopic Nude Mouse Model of Oral Tongue Squamous Cell Carcinoma

Jeffrey N. Myers, F. Christopher Holsinger, Samar A. Jasser, B. Nebiyou Bekele, Isaiah J. Fidler
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (1): 293–298.
Published: 01 January 2002
View article titled, An Orthotopic Nude Mouse Model of Oral Tongue Squamous Cell Carcinoma
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