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Aristotelis Tsirigos
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Journal Articles

Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma

Eileen M. Boyle, Patrick Blaney, James H. Stoeckle, Yubao Wang, Hussein Ghamlouch, Dylan Gagler, Marc Braunstein, Louis Williams, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, Jason Avigan, Alexander Li, Monica Jinsi, David Kaminetzsky, Arnaldo Arbini, Lydia Montes, Jill Corre, Even H. Rustad, Ola Landgren, Francesco Maura, Brian A. Walker, Michael Bauer, Benedetto Bruno, Aristotelis Tsirigos, Faith E. Davies, Gareth J. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3901–3913.
https://doi.org/10.1158/1078-0432.CCR-22-3209
Published: 02 October 2023
View article titled, Multiomic Mapping of Acquired Chromosome 1 Copy-Number and Structural Variants to Identify Therapeutic Vulnerabilities in Multiple Myeloma
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Includes: Supplementary data
Journal Articles

DNA Methylation Profiling Identifies Subgroups of Lung Adenocarcinoma with Distinct Immune Cell Composition, DNA Methylation Age, and Clinical Outcome

Kayla Guidry, Varshini Vasudevaraja, Kristen Labbe, Hussein Mohamed, Jonathan Serrano, Brett W. Guidry, Michael DeLorenzo, Hua Zhang, Jiehui Deng, Soumyadip Sahu, Christina Almonte, Andre L. Moreira, Aristotelis Tsirigos, Thales Papagiannakopoulos, Harvey Pass, Matija Snuderl, Kwok-Kin Wong
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3824–3835.
https://doi.org/10.1158/1078-0432.CCR-22-0391
Published: 01 September 2022
View article titled, DNA Methylation Profiling Identifies Subgroups of Lung Adenocarcinoma with Distinct Immune Cell Composition, DNA Methylation Age, and Clinical Outcome
Open the PDF for DNA Methylation Profiling Identifies Subgroups of Lung Adenocarcinoma with Distinct Immune Cell Composition, DNA Methylation Age, and Clinical Outcome in another window
Includes: Supplementary data
Journal Articles

Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma

Paul Johannet, Nicolas Coudray, Douglas M. Donnelly, George Jour, Irineu Illa-Bochaca, Yuhe Xia, Douglas B. Johnson, Lee Wheless, James R. Patrinely, Sofia Nomikou, David L. Rimm, Anna C. Pavlick, Jeffrey S. Weber, Judy Zhong, Aristotelis Tsirigos, Iman Osman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (1): 131–140.
https://doi.org/10.1158/1078-0432.CCR-20-2415
Published: 04 January 2021
View article titled, Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma
Open the PDF for Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma in another window
Includes: Supplementary data
Journal Articles

Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase–mutant Glioma

Marissa Spino, Sylvia C. Kurz, Luis Chiriboga, Jonathan Serrano, Briana Zeck, Namita Sen, Seema Patel, Guomiao Shen, Varshini Vasudevaraja, Aristotelis Tsirigos, Carter M. Suryadevara, Joshua D. Frenster, Kensuke Tateishi, Hiroaki Wakimoto, Rajan Jain, Howard A. Riina, Theodore P. Nicolaides, Erik P. Sulman, Daniel P. Cahill, John G. Golfinos, Kumiko Isse, Laura R. Saunders, David Zagzag, Dimitris G. Placantonakis, Matija Snuderl, Andrew S. Chi
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (4): 1261–1271.
https://doi.org/10.1158/1078-0432.CCR-18-2312
Published: 15 February 2019
View article titled, Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase–mutant Glioma
Open the PDF for Cell Surface Notch Ligand DLL3 is a Therapeutic Target in Isocitrate Dehydrogenase–mutant Glioma in another window
Includes: Supplementary data
Journal Articles

Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management

Kasthuri S. Kannan, Aristotelis Tsirigos, Jonathan Serrano, Lynn Ann Forrester, Arline Faustin, Cheddhi Thomas, David Capper, Volker Hovestadt, Stefan M. Pfister, David T. W Jones, Martin Sill, Daniel Schrimpf, Andreas von Deimling, Adriana Heguy, Sharon L. Gardner, Jeffrey Allen, Cyrus Hedvat, David Zagzag, Matija Snuderl, Matthias A. Karajannis
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (1_Supplement): 11.
https://doi.org/10.1158/1557-3265.PMSCLINGEN15-11
Published: 03 January 2016
View article titled, Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management