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Journal Articles

Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer

Shin Saito, Michihisa Kono, Hoang C.B. Nguyen, Ann Marie Egloff, Cameron Messier, Patrick Lizotte, Cloud Paweletz, Douglas Adkins, Ravindra Uppaluri

Clin Cancer Res (2024) 30 (9): 1934–1944.

https://doi.org/10.1158/1078-0432.CCR-23-3477

Published: 01 May 2024

View article titled, Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer

Includes: Supplementary data

Journal Articles

Abstract PO-078: Tissue-resident memory CD8+ T cells correlate with anti-PD-1 response in head and neck cancer and expand upon cDC1 activation in tumor-draining lymph nodes to overcome PD-1 resistance

Michihisa Kono, Shin Saito, Geoff Ivison, Ayano Kondo, Aaron Mayer, Jonathan D. Schoenfeld, Ann Marie Egloff, Ravindra Uppaluri

Clin Cancer Res (2023) 29 (18_Supplement): PO-078.

https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-078

Published: 15 September 2023

View article titled, Abstract PO-078: Tissue-resident memory CD8+ T cells correlate with anti-PD-1 response in head and neck cancer and expand upon cDC1 activation in tumor-draining lymph nodes to overcome PD-1 resistance

Journal Articles

Abstract PO-001: Circulating tumor-tissue modified HPV DNA testing in the clinical workup of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV Study

Sana Batool, Rosh K. V. Sethi, Annette Wang, Kirsten Dabekaussen, Ann Marie Egloff, Catherine Delvecchio Fitz, Ravindra Uppaluri, Jennifer Shin, Eleni M. Rettig

Clin Cancer Res (2023) 29 (18_Supplement): PO-001.

https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-001

Published: 15 September 2023

View article titled, Abstract PO-001: Circulating tumor-tissue modified HPV DNA testing in the clinical workup of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV Study

Journal Articles

Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck

Clin Cancer Res (2022) 28 (3): 468–478.

https://doi.org/10.1158/1078-0432.CCR-21-2635

Published: 01 February 2022

View article titled, Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck

Includes: Supplementary data

Journal Articles

Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

Tenny Mudianto, Katie M. Campbell, Jason Webb, Paul Zolkind, Zachary L. Skidmore, Rachel Riley, Erica K. Barnell, Ibrahim Ozgenc, Tusar Giri, Gavin P. Dunn, Douglas R. Adkins, Malachi Griffith, Ann Marie Egloff, Obi L. Griffith, Ravindra Uppaluri

Clin Cancer Res (2021) 27 (8): 2326–2339.

https://doi.org/10.1158/1078-0432.CCR-19-4179

Published: 15 April 2021

View article titled, Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

Includes: Supplementary data

Journal Articles

Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Clin Cancer Res (2021) 27 (1): 357.

https://doi.org/10.1158/1078-0432.CCR-20-4484

Published: 04 January 2021

View article titled, Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Journal Articles

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Clin Cancer Res (2020) 26 (19): 5140–5152.

https://doi.org/10.1158/1078-0432.CCR-20-1695

Published: 01 October 2020

View article titled, Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Includes: Supplementary data

Journal Articles

Abstract B39: Generation of head and neck cancer patient-derived xenografts with in vivo acquired cetuximab resistance

Pei Zhou, Hua Li, Sarah Wheeler, Jennifer R. Grandis, Laura A. Stabile, Ann Marie Egloff

Clin Cancer Res (2015) 21 (4_Supplement): B39.

https://doi.org/10.1158/1557-3265.PMS14-B39

Published: 13 February 2015

View article titled, Abstract B39: Generation of head and neck cancer patient-derived xenografts with in vivo acquired cetuximab resistance

Journal Articles

Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

Ann Marie Egloff, Ju-Whei Lee, Corey J. Langer, Harry Quon, Alec Vaezi, Jennifer R. Grandis, Raja R. Seethala, Lin Wang, Dong M. Shin, Athanassios Argiris, Donghua Yang, Ranee Mehra, John Andrew Ridge, Urjeet A. Patel, Barbara A. Burtness, Arlene A. Forastiere

Clin Cancer Res (2014) 20 (19): 5041–5051.

https://doi.org/10.1158/1078-0432.CCR-14-0051

Published: 30 September 2014

View article titled, Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

Includes: Supplementary data

Journal Articles

SHP2 Is Overexpressed and Inhibits pSTAT1-Mediated APM Component Expression, T-cell Attracting Chemokine Secretion, and CTL Recognition in Head and Neck Cancer Cells

Michael S. Leibowitz, Raghvendra M. Srivastava, Pedro A. Andrade Filho, Ann Marie Egloff, Lin Wang, Raja R. Seethala, Soldano Ferrone, Robert L. Ferris

Clin Cancer Res (2013) 19 (4): 798–808.

https://doi.org/10.1158/1078-0432.CCR-12-1517

Published: 14 February 2013

View article titled, SHP2 Is Overexpressed and Inhibits pSTAT1-Mediated APM Component Expression, T-cell Attracting Chemokine Secretion, and CTL Recognition in Head and Neck Cancer Cells

Includes: Supplementary data

Journal Articles

Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy

Ann Marie Egloff, Jennifer R. Grandis

Clin Cancer Res (2012) 18 (19): 5188–5195.

https://doi.org/10.1158/1078-0432.CCR-11-2258

Published: 30 September 2012

View article titled, Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy

Journal Articles

Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

Sarah Wheeler, Doris R. Siwak, Raymond Chai, Courtney LaValle, Raja R. Seethala, Lin Wang, Kathleen Cieply, Carol Sherer, Corwin Joy, Gordon B. Mills, Athanassios Argiris, Jill M. Siegfried, Jennifer R. Grandis, Ann Marie Egloff

Clin Cancer Res (2012) 18 (8): 2278–2289.

https://doi.org/10.1158/1078-0432.CCR-11-1593

Published: 16 April 2012

View article titled, Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

Includes: Supplementary data

Journal Articles

Response to Combined Molecular Targeting: Defining the Role of P-STAT3

Ann Marie Egloff, Jennifer R. Grandis

Clin Cancer Res (2011) 17 (3): 393–395.

https://doi.org/10.1158/1078-0432.CCR-10-2925

Published: 01 February 2011

View article titled, Response to Combined Molecular Targeting: Defining the Role of P-STAT3

Includes: Supplementary data

Journal Articles

Nuclear Localization of Signal Transducer and Activator of Transcription 3 in Head and Neck Squamous Cell Carcinoma Is Associated with a Better Prognosis

Eirini Pectasides, Ann-Marie Egloff, Clarence Sasaki, Panteleimon Kountourakis, Barbara Burtness, George Fountzilas, Urania Dafni, Thomas Zaramboukas, Theodoros Rampias, David Rimm, Jennifer Grandis, Amanda Psyrri

Clin Cancer Res (2010) 16 (8): 2427–2434.

https://doi.org/10.1158/1078-0432.CCR-09-2658

Published: 14 April 2010

View article titled, Nuclear Localization of Signal Transducer and Activator of Transcription 3 in Head and Neck Squamous Cell Carcinoma Is Associated with a Better Prognosis

Includes: Supplementary data

Journal Articles

Cross-Talk between Estrogen Receptor and Epidermal Growth Factor Receptor in Head and Neck Squamous Cell Carcinoma

Ann Marie Egloff, Mary E. Rothstein, Raja Seethala, Jill M. Siegfried, Jennifer Rubin Grandis, Laura P. Stabile

Clin Cancer Res (2009) 15 (21): 6529–6540.

https://doi.org/10.1158/1078-0432.CCR-09-0862

Published: 02 November 2009

View article titled, Cross-Talk between Estrogen Receptor and Epidermal Growth Factor Receptor in Head and Neck Squamous Cell Carcinoma

Journal Articles

HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

Lynn M. Knowles, Laura P. Stabile, Ann Marie Egloff, Mary E. Rothstein, Sufi M. Thomas, Christopher T. Gubish, Edwina C. Lerner, Raja R. Seethala, Shinsuke Suzuki, Kelly M. Quesnelle, Sarah Morgan, Robert L. Ferris, Jennifer R. Grandis, Jill M. Siegfried

Clin Cancer Res (2009) 15 (11): 3740–3750.

https://doi.org/10.1158/1078-0432.CCR-08-3252

Published: 01 June 2009

View article titled, HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

Includes: Supplementary data

Journal Articles

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Priya Koppikar, Seung-Ho Choi, Ann Marie Egloff, Quan Cai, Shinsuke Suzuki, Maria Freilino, Hiroshi Nozawa, Sufi M. Thomas, William E. Gooding, Jill M. Siegfried, Jennifer R. Grandis

Clin Cancer Res (2008) 14 (13): 4284–4291.

https://doi.org/10.1158/1078-0432.CCR-07-5226

Published: 01 July 2008

View article titled, Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

NARROW

Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer

Abstract PO-078: Tissue-resident memory CD8+ T cells correlate with anti-PD-1 response in head and neck cancer and expand upon cDC1 activation in tumor-draining lymph nodes to overcome PD-1 resistance

Abstract PO-001: Circulating tumor-tissue modified HPV DNA testing in the clinical workup of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV Study

Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck

Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Abstract B39: Generation of head and neck cancer patient-derived xenografts with in vivo acquired cetuximab resistance

Phase II Study of Cetuximab in Combination with Cisplatin and Radiation in Unresectable, Locally Advanced Head and Neck Squamous Cell Carcinoma: Eastern Cooperative Oncology Group Trial E3303

SHP2 Is Overexpressed and Inhibits pSTAT1-Mediated APM Component Expression, T-cell Attracting Chemokine Secretion, and CTL Recognition in Head and Neck Cancer Cells

Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy

Tumor Epidermal Growth Factor Receptor and EGFR PY1068 Are Independent Prognostic Indicators for Head and Neck Squamous Cell Carcinoma

Response to Combined Molecular Targeting: Defining the Role of P-STAT3

Nuclear Localization of Signal Transducer and Activator of Transcription 3 in Head and Neck Squamous Cell Carcinoma Is Associated with a Better Prognosis

Cross-Talk between Estrogen Receptor and Epidermal Growth Factor Receptor in Head and Neck Squamous Cell Carcinoma

HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

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