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Angelika Eggert
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Journal Articles

Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma

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Marco Lodrini, Josefine Graef, Theresa M. Thole-Kliesch, Kathy Astrahantseff, Annika Sprüssel, Maddalena Grimaldi, Constantin Peitz, Rasmus B. Linke, Jan F. Hollander, Erwin Lankes, Annette Künkele, Lena Oevermann, Georg Schwabe, Jörg Fuchs, Annabell Szymansky, Johannes H. Schulte, Patrick Hundsdörfer, Cornelia Eckert, Holger Amthauer, Angelika Eggert, Hedwig E. Deubzer
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (9): 1809–1820.
https://doi.org/10.1158/1078-0432.CCR-21-3716
Published: 02 May 2022
View articletitled, Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma
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Includes: Supplementary data
Journal Articles

ALK Inhibitors in Neuroblastoma: A Sprint from Bench to Bedside

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Johannes H. Schulte, Angelika Eggert
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3507–3509.
https://doi.org/10.1158/1078-0432.CCR-21-0627
Published: 01 July 2021
View articletitled, ALK Inhibitors in Neuroblastoma: A Sprint from Bench to Bedside
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Journal Articles

Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition

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Anton Henssen, Kristina Althoff, Andrea Odersky, Anneleen Beckers, Richard Koche, Frank Speleman, Simon Schäfers, Emma Bell, Maike Nortmeyer, Frank Westermann, Katleen De Preter, Alexandra Florin, Lukas Heukamp, Annika Spruessel, Kathy Astrahanseff, Sven Lindner, Natalie Sadowski, Alexander Schramm, Lucile Astorgues-Xerri, Maria E. Riveiro, Angelika Eggert, Esteban Cvitkovic, Johannes H. Schulte
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (10): 2470–2481.
https://doi.org/10.1158/1078-0432.CCR-15-1449
Published: 12 May 2016
View articletitled, Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition
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Includes: Supplementary data
Journal Articles

miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples

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Katleen De Preter, Pieter Mestdagh, Joëlle Vermeulen, Fjoralba Zeka, Arlene Naranjo, Isabella Bray, Victoria Castel, Caifu Chen, Elzbieta Drozynska, Angelika Eggert, Michael D. Hogarty, Ewa Iżycka-Swieszewska, Wendy B. London, Rosa Noguera, Marta Piqueras, Kenneth Bryan, Benjamin Schowe, Peter van Sluis, Jan J. Molenaar, Alexander Schramm, Johannes H. Schulte, Raymond L. Stallings, Rogier Versteeg, Geneviève Laureys, Nadine Van Roy, Frank Speleman, Jo Vandesompele
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7684–7692.
https://doi.org/10.1158/1078-0432.CCR-11-0610
Published: 18 December 2011
View articletitled, miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples
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Includes: Supplementary data
Journal Articles

High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma

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Johannes H. Schulte, Hagen S. Bachmann, Bent Brockmeyer, Katleen DePreter, André Oberthür, Sandra Ackermann, Yvonne Kahlert, Kristian Pajtler, Jessica Theissen, Frank Westermann, Jo Vandesompele, Frank Speleman, Frank Berthold, Angelika Eggert, Benedikt Brors, Barbara Hero, Alexander Schramm, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 5082–5092.
https://doi.org/10.1158/1078-0432.CCR-10-2809
Published: 31 July 2011
View articletitled, High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
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Includes: Supplementary data
Journal Articles

Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma

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Sandra Ackermann, Felix Goeser, Johannes H. Schulte, Alexander Schramm, Volker Ehemann, Barbara Hero, Angelika Eggert, Frank Berthold, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 731–741.
https://doi.org/10.1158/1078-0432.CCR-10-1129
Published: 15 February 2011
View articletitled, Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma
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Journal Articles

Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

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Sara De Brouwer, Katleen De Preter, Candy Kumps, Piotr Zabrocki, Michaël Porcu, Ellen M. Westerhout, Arjan Lakeman, Jo Vandesompele, Jasmien Hoebeeck, Tom Van Maerken, Anne De Paepe, Geneviève Laureys, Johannes H. Schulte, Alexander Schramm, Caroline Van Den Broecke, Joëlle Vermeulen, Nadine Van Roy, Klaus Beiske, Marleen Renard, Rosa Noguera, Olivier Delattre, Isabelle Janoueix-Lerosey, Per Kogner, Tommy Martinsson, Akira Nakagawara, Miki Ohira, Huib Caron, Angelika Eggert, Jan Cools, Rogier Versteeg, Frank Speleman
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (17): 4353–4362.
https://doi.org/10.1158/1078-0432.CCR-09-2660
Published: 31 August 2010
View articletitled, Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification
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Includes: Supplementary data
Journal Articles

Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma

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Patrick G. Buckley, Leah Alcock, Kenneth Bryan, Isabella Bray, Johannes H. Schulte, Alexander Schramm, Angelika Eggert, Pieter Mestdagh, Katleen De Preter, Jo Vandesompele, Frank Speleman, Raymond L. Stallings
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (11): 2971–2978.
https://doi.org/10.1158/1078-0432.CCR-09-3215
Published: 31 May 2010
View articletitled, Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma
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Includes: Supplementary data
Journal Articles

Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature

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Katleen De Preter, Joëlle Vermeulen, Benedikt Brors, Olivier Delattre, Angelika Eggert, Matthias Fischer, Isabelle Janoueix-Lerosey, Cinzia Lavarino, John M. Maris, Jaume Mora, Akira Nakagawara, André Oberthuer, Miki Ohira, Gudrun Schleiermacher, Alexander Schramm, Johannes H. Schulte, Qun Wang, Frank Westermann, Frank Speleman, Jo Vandesompele
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1532–1541.
https://doi.org/10.1158/1078-0432.CCR-09-2607
Published: 28 February 2010
View articletitled, Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature
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Includes: Supplementary data
Journal Articles

Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds

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Katleen De Preter, Sara De Brouwer, Tom Van Maerken, Filip Pattyn, Alexander Schramm, Angelika Eggert, Jo Vandesompele, Frank Speleman
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (11): 3690–3696.
https://doi.org/10.1158/1078-0432.CCR-08-2699
Published: 01 June 2009
View articletitled, Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds
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Includes: Supplementary data
Journal Articles

Targeting the Phosphoinositide 3-Kinase Isoform p110δ Impairs Growth and Survival in Neuroblastoma Cells

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Danielle Boller, Alexander Schramm, Kathrin T. Doepfner, Tarek Shalaby, André O. von Bueren, Angelika Eggert, Michael A. Grotzer, Alexandre Arcaro
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (4): 1172–1181.
https://doi.org/10.1158/1078-0432.CCR-07-0737
Published: 15 February 2008
View articletitled, Targeting the Phosphoinositide 3-Kinase Isoform p110δ Impairs Growth and Survival in Neuroblastoma Cells
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Includes: Supplementary data
Journal Articles

Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome

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Alexander Schramm, Jo Vandesompele, Johannes H. Schulte, Sabine Dreesmann, Lars Kaderali, Benedikt Brors, Roland Eils, Frank Speleman, Angelika Eggert
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (5): 1459–1465.
https://doi.org/10.1158/1078-0432.CCR-06-2032
Published: 01 March 2007
View articletitled, Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome
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Journal Articles

Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia

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Daniel Steinbach, Alexander Schramm, Angelika Eggert, Masanori Onda, Kristin Dawczynski, Andreas Rump, Ira Pastan, Susann Wittig, Nadine Pfaffendorf, Astrid Voigt, Felix Zintl, Bernd Gruhn
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (8): 2434–2441.
https://doi.org/10.1158/1078-0432.CCR-05-2552
Published: 25 April 2006
View articletitled, Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia
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Journal Articles

MYC Messenger RNA Expression Predicts Survival Outcome in Childhood Primitive Neuroectodermal Tumor/Medulloblastoma

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Michael A. Grotzer, Michael D. Hogarty, Anna J. Janss, Xueyuan Liu, Huaquing Zhao, Angelika Eggert, Leslie N. Sutton, Lucy B. Rorke, Garrett M. Brodeur, Peter C. Phillips
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (8): 2425–2433.
Published: 01 August 2001
View articletitled, MYC Messenger RNA Expression Predicts Survival Outcome in Childhood Primitive Neuroectodermal Tumor/Medulloblastoma
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Journal Articles

High-Level Expression of Angiogenic Factors Is Associated with Advanced Tumor Stage in Human Neuroblastomas

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Angelika Eggert, Naohiko Ikegaki, Janet Kwiatkowski, Huaqing Zhao, Garrett M. Brodeur, Bruce P. Himelstein
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (5): 1900–1908.
Published: 01 May 2000
View articletitled, High-Level Expression of Angiogenic Factors Is Associated with Advanced Tumor Stage in Human Neuroblastomas
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