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Aneel Paulus
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Journal Articles

Novel BCL-2 Inhibitor Lisaftoclax in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematologic Malignancies: First-in-Human Open-Label Trial

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Sikander Ailawadhi, Zi Chen, Bo Huang, Aneel Paulus, Mary C. Collins, Lei (Tommy) Fu, Mingyu Li, Mohammad Ahmad, Lichuang Men, Hengbang Wang, Matthew S. Davids, Eric Liang, Divya J. Mekala, Zhicong He, Masa Lasica, Costas K. Yannakou, Ricardo Parrondo, Laura Glass, Dajun Yang, Asher Chanan-Khan, Yifan Zhai
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (13): 2385–2393.
https://doi.org/10.1158/1078-0432.CCR-22-3321
Published: 05 July 2023
View articletitled, Novel BCL-2 Inhibitor Lisaftoclax in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematologic Malignancies: First-in-Human Open-Label Trial
Open the PDF for Novel BCL-2 Inhibitor Lisaftoclax in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematologic Malignancies: First-in-Human Open-Label Trial in another window
Includes: Supplementary data
Journal Articles

Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies

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Patrizia Mondello, Jonas Paludo, Joseph P. Novak, Kerstin Wenzl, Zhi-Zhang Yang, Shahrzad Jalali, Jordan E. Krull, Esteban Braggio, Surendra Dasari, Michelle K. Manske, Jithma A. Abeykoon, Vivekananda Sarangi, Prashant Kapoor, Aneel Paulus, Craig B. Reeder, Sikander Ailawadhi, Asher A. Chanan-Khan, Robert A. Kyle, Morie A. Gertz, Anne J. Novak, Stephen M. Ansell
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (5): 957–970.
https://doi.org/10.1158/1078-0432.CCR-22-2215
Published: 01 March 2023
View articletitled, Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies
Open the PDF for Molecular Clusters and Tumor-Immune Drivers of IgM Monoclonal Gammopathies in another window
Includes: Supplementary data
Journal Articles

Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy

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Jing Deng, Aneel Paulus, Douglas D. Fang, Alak Manna, Guangfeng Wang, Hengbang Wang, Saijie Zhu, Jianyong Chen, Ping Min, Yan Yin, Navnita Dutta, Nabanita Halder, Gina Ciccio, John A. Copland, III, James Miller, Bing Han, Longchuan Bai, Liu Liu, Mi Wang, Donna McEachern, Sally Przybranowski, Chao-Yie Yang, Jeanne A. Stuckey, Depei Wu, Caixia Li, Jeremy Ryan, Anthony Letai, Sikander Ailawadhi, Dajun Yang, Shaomeng Wang, Asher Chanan-Khan, Yifan Zhai
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5455–5468.
https://doi.org/10.1158/1078-0432.CCR-21-4037
Published: 15 December 2022
View articletitled, Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy
Open the PDF for Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy in another window
Includes: Supplementary data
Journal Articles

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

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Alak Manna, Sonikpreet Aulakh, Prachi Jani, Salman Ahmed, Sharoon Akhtar, Marie Coignet, Michael Heckman, Zahara Meghji, Kirtipal Bhatia, Aarushi Sharma, Taimur Sher, Victoria Alegria, Fabio Malavasi, Eduardo N. Chini, Asher Chanan-Khan, Sikander Ailawadhi, Aneel Paulus
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3974–3985.
https://doi.org/10.1158/1078-0432.CCR-18-3412
Published: 01 July 2019
View articletitled, Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia
Open the PDF for Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia in another window
Includes: Supplementary data