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Journal Articles

Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma

Andrew B. Lassman, Lisa Roberts-Rapp, Irina Sokolova, Minghao Song, Ekaterina Pestova, Rupinder Kular, Carolyn Mullen, Zheng Zha, Xin Lu, Erica Gomez, Anahita Bhathena, David Maag, Priya Kumthekar, Hui K. Gan, Andrew M. Scott, Maria Guseva, Kyle D. Holen, Peter J. Ansell, Martin J. van den Bent

Clin Cancer Res (2019) 25 (11): 3259–3265.

https://doi.org/10.1158/1078-0432.CCR-18-3034

Published: 03 June 2019

View articletitled, Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma

Includes: Supplementary data

Journal Articles

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Ingrid J.G. Burvenich, Fook T. Lee, Glenn A. Cartwright, Graeme J. O'Keefe, Dahna Makris, Diana Cao, Sylvia Gong, Anderly C. Chueh, John M. Mariadason, Martin W. Brechbiel, Robert A. Beckman, Kosaku Fujiwara, Reinhard von Roemeling, Andrew M. Scott

Clin Cancer Res (2013) 19 (21): 5984–5993.

https://doi.org/10.1158/1078-0432.CCR-12-3104

Published: 31 October 2013

View articletitled, Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Includes: Supplementary data

Journal Articles

Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies

Eliane Fischer, Krishna Chaitanya, Thomas Wüest, Andreas Wadle, Andrew M. Scott, Maries van den Broek, Roger Schibli, Stefan Bauer, Christoph Renner

Clin Cancer Res (2012) 18 (22): 6208–6218.

https://doi.org/10.1158/1078-0432.CCR-12-0644

Published: 14 November 2012

View articletitled, Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies

Includes: Supplementary data

Journal Articles

Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Rebecca A. Herbertson, Niall C. Tebbutt, Fook-Thean Lee, David J. MacFarlane, Bridget Chappell, Noel Micallef, Sze-Ting Lee, Timothy Saunder, Wendie Hopkins, Fiona E. Smyth, David K. Wyld, John Bellen, Daryl S. Sonnichsen, Martin W. Brechbiel, Carmel Murone, Andrew M. Scott

Clin Cancer Res (2009) 15 (21): 6709–6715.

https://doi.org/10.1158/1078-0432.CCR-09-0536

Published: 02 November 2009

View articletitled, Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Journal Articles

Radioimmunotherapy with α-Particle–Emitting ²¹³Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

Marcus P. Kelly, Fook T. Lee, Kiki Tahtis, Fiona E. Smyth, Martin W. Brechbiel, Andrew M. Scott

Clin Cancer Res (2007) 13 (18): 5604s–5612s.

https://doi.org/10.1158/1078-0432.CCR-07-1071

Published: 17 September 2007

View articletitled, Radioimmunotherapy with α-Particle–Emitting 213Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

Journal Articles

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Clin Cancer Res (2007) 13 (11): 3286–3292.

https://doi.org/10.1158/1078-0432.CCR-07-0284

Published: 01 June 2007

View articletitled, A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Journal Articles

The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization

Terrance G. Johns, Rushika M. Perera, Sonja C. Vernes, Angela A. Vitali, Diana X. Cao, Webster K. Cavenee, Andrew M. Scott, Frank B. Furnari

Clin Cancer Res (2007) 13 (6): 1911–1925.

https://doi.org/10.1158/1078-0432.CCR-06-1453

Published: 15 March 2007

View articletitled, The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization

Journal Articles

HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan

Shigehisa Kitano, Shinichi Kageyama, Yasuhiro Nagata, Yoshihiro Miyahara, Atsunori Hiasa, Hiroaki Naota, Satoshi Okumura, Hiroshi Imai, Taizo Shiraishi, Masahiro Masuya, Masakatsu Nishikawa, Junzo Sunamoto, Kazunari Akiyoshi, Takashi Kanematsu, Andrew M. Scott, Roger Murphy, Eric W. Hoffman, Lloyd J. Old, Hiroshi Shiku

Clin Cancer Res (2006) 12 (24): 7397–7405.

https://doi.org/10.1158/1078-0432.CCR-06-1546

Published: 22 December 2006

View articletitled, HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan

Journal Articles

Enhanced Efficacy of Radioimmunotherapy with ⁹⁰Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Fook T. Lee, Angela J. Mountain, Marcus P. Kelly, Cathrine Hall, Angela Rigopoulos, Terrance G. Johns, Fiona E. Smyth, Martin W. Brechbiel, Edouard C. Nice, Antony W. Burgess, Andrew M. Scott

Clin Cancer Res (2005) 11 (19): 7080s–7086s.

https://doi.org/10.1158/1078-0432.CCR-1004-0019

Published: 03 October 2005

View articletitled, Enhanced Efficacy of Radioimmunotherapy with 90Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Journal Articles

Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity

Rushika M. Perera, Yoshitaka Narita, Frank B. Furnari, Hui K. Gan, Carmel Murone, Marika Ahlkvist, Rodney B. Luwor, Antony W. Burgess, Elisabeth Stockert, Achim A. Jungbluth, Lloyd J. Old, Webster K. Cavenee, Andrew M. Scott, Terrance G. Johns

Clin Cancer Res (2005) 11 (17): 6390–6399.

https://doi.org/10.1158/1078-0432.CCR-04-2653

Published: 06 September 2005

View articletitled, Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity

Journal Articles

A Phase I Trial of Humanized Monoclonal Antibody A33 in Patients with Colorectal Carcinoma: Biodistribution, Pharmacokinetics, and Quantitative Tumor Uptake

Clin Cancer Res (2005) 11 (13): 4810–4817.

https://doi.org/10.1158/1078-0432.CCR-04-2329

Published: 06 July 2005

View articletitled, A Phase I Trial of Humanized Monoclonal Antibody A33 in Patients with Colorectal Carcinoma: Biodistribution, Pharmacokinetics, and Quantitative Tumor Uptake

Journal Articles

Phase I Trial of ¹³¹I-huA33 in Patients with Advanced Colorectal Carcinoma

Clin Cancer Res (2005) 11 (13): 4818–4826.

https://doi.org/10.1158/1078-0432.CCR-04-2330

Published: 06 July 2005

View articletitled, Phase I Trial of 131I-huA33 in Patients with Advanced Colorectal Carcinoma

Journal Articles

A Phase I Dose-Escalation Study of Sibrotuzumab in Patients with Advanced or Metastatic Fibroblast Activation Protein-positive Cancer

Clin Cancer Res (2003) 9 (5): 1639–1647.

Published: 01 May 2003

View articletitled, A Phase I Dose-Escalation Study of Sibrotuzumab in Patients with Advanced or Metastatic Fibroblast Activation Protein-positive Cancer

Journal Articles

Biodistribution Properties of ¹¹¹Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)₂ Constructs in a Breast Carcinoma Xenograft Model

Kiki Tahtis, Fook-Thean Lee, Fiona E. Smyth, Barbara E. Power, Christoph Renner, Martin W. Brechbiel, Lloyd J. Old, Peter J. Hudson, Andrew M. Scott

Clin Cancer Res (2001) 7 (4): 1061–1072.

Published: 01 April 2001

View articletitled, Biodistribution Properties of 111Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)2 Constructs in a Breast Carcinoma Xenograft Model

Journal Articles

Therapeutic Efficacy of Anti-Lewis^y Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

Kerrie Clarke, Fook-Thean Lee, Martin W. Brechbiel, Fiona E. Smyth, Lloyd J. Old, Andrew M. Scott

Clin Cancer Res (2000) 6 (9): 3621–3628.

Published: 01 September 2000

View articletitled, Therapeutic Efficacy of Anti-Lewisy Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

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Comparison of Biomarker Assays for EGFR: Implications for Precision Medicine in Patients with Glioblastoma

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008

Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies

Phase I Biodistribution and Pharmacokinetic Study of Lewis Y–Targeting Immunoconjugate CMD-193 in Patients with Advanced Epithelial Cancers

Radioimmunotherapy with α-Particle–Emitting ²¹³Bi-C-Functionalized trans-Cyclohexyl-Diethylenetriaminepentaacetic Acid-Humanized 3S193 Is Enhanced by Combination with Paclitaxel Chemotherapy

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

The Efficacy of Epidermal Growth Factor Receptor–Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization

HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan

Enhanced Efficacy of Radioimmunotherapy with ⁹⁰Y-CHX-A″-DTPA-hu3S193 by Inhibition of Epidermal Growth Factor Receptor (EGFR) Signaling with EGFR Tyrosine Kinase Inhibitor AG1478

Treatment of Human Tumor Xenografts with Monoclonal Antibody 806 in Combination with a Prototypical Epidermal Growth Factor Receptor–Specific Antibody Generates Enhanced Antitumor Activity

A Phase I Trial of Humanized Monoclonal Antibody A33 in Patients with Colorectal Carcinoma: Biodistribution, Pharmacokinetics, and Quantitative Tumor Uptake

Phase I Trial of ¹³¹I-huA33 in Patients with Advanced Colorectal Carcinoma

A Phase I Dose-Escalation Study of Sibrotuzumab in Patients with Advanced or Metastatic Fibroblast Activation Protein-positive Cancer

Biodistribution Properties of ¹¹¹Indium-labeled C-Functionalized trans-Cyclohexyl Diethylenetriaminepentaacetic Acid Humanized 3S193 Diabody and F(ab′)₂ Constructs in a Breast Carcinoma Xenograft Model

Therapeutic Efficacy of Anti-Lewis^y Humanized 3S193 Radioimmunotherapy in a Breast Cancer Model: Enhanced Activity When Combined with Taxol Chemotherapy

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