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Andreas von Deimling
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Journal Articles

Cerebrospinal Fluid cfDNA Sequencing for Classification of Central Nervous System Glioma

Open Access
Florian Iser, Felix Hinz, Dirk C. Hoffmann, Niklas Grassl, Cansu Güngoör, Jochen Meyer, Laura Dörner, Lea Hofmann, Vanessa Kelbch, Kirsten Göbel, Mustafa Ahmed Mahmutoglu, Philipp Vollmuth, Areeba Patel, Duy Nguyen, Leon D. Kaulen, Iris Mildenberger, Katharina Sahm, Kendra Maaß, Kristian W. Pajtler, Ganesh M. Shankar, Markus Weiler, Brigitte Wildemann, Frank Winkler, Andreas von Deimling, Michael Platten, Wolfgang Wick, Felix Sahm, Tobias Kessler
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (14): 2974–2985.
https://doi.org/10.1158/1078-0432.CCR-23-2907
Published: 15 July 2024
View articletitled, Cerebrospinal Fluid cfDNA Sequencing for Classification of Central Nervous System Glioma
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Includes: Supplementary data
Journal Articles

Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Available to Purchase
Valentina Fermi, Rolf Warta, Amélie Wöllner, Catharina Lotsch, Lena Jassowicz, Carmen Rapp, Maximilian Knoll, Gerhard Jungwirth, Christine Jungk, Philip Dao Trong, Andreas von Deimling, Amir Abdollahi, Andreas Unterberg, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (22): 4685–4697.
https://doi.org/10.1158/1078-0432.CCR-23-0576
Published: 14 November 2023
View articletitled, Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580
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Includes: Supplementary data
Journal Articles

Prognostic Markers of DNA Methylation and Next-Generation Sequencing in Progressive Glioblastoma from the EORTC-26101 Trial

Open Access
Tobias Kessler, Daniel Schrimpf, Laura Doerner, Ling Hai, Leon D. Kaulen, Jakob Ito, Martin van den Bent, Martin Taphoorn, Alba A. Brandes, Ahmed Idbaih, Julien Dômont, Paul M. Clement, Mario Campone, Martin Bendszus, Andreas von Deimling, Felix Sahm, Michael Platten, Wolfgang Wick, Antje Wick
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (19): 3892–3900.
https://doi.org/10.1158/1078-0432.CCR-23-0926
Published: 02 October 2023
View articletitled, Prognostic Markers of DNA Methylation and Next-Generation Sequencing in Progressive Glioblastoma from the EORTC-26101 Trial
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Includes: Supplementary data
Journal Articles

Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial

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C. Mircea S. Tesileanu, Marc Sanson, Wolfgang Wick, Alba A. Brandes, Paul M. Clement, Sara C. Erridge, Michael A. Vogelbaum, Anna K. Nowak, Jean-Francois Baurain, Warren P. Mason, Helen Wheeler, Olivier L. Chinot, Sanjeev Gill, Matthew Griffin, Leland Rogers, Walter Taal, Roberta Rudà, Michael Weller, Catherine McBain, Myra E. van Linde, Kenneth Aldape, Robert B. Jenkins, Johan M. Kros, Pieter Wesseling, Andreas von Deimling, Youri Hoogstrate, Iris de Heer, Peggy N. Atmodimedjo, Hendrikus J. Dubbink, Rutger W.W. Brouwer, Wilfred F.J. van IJcken, Kin Jip Cheung, Vassilis Golfinopoulos, Brigitta G. Baumert, Thierry Gorlia, Pim J. French, Martin J. van den Bent
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2527–2535.
https://doi.org/10.1158/1078-0432.CCR-21-4283
Published: 13 June 2022
View articletitled, Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial
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Includes: Supplementary data
Journal Articles

T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas

Open Access
Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K. Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O. Breckwoldt, Gerald Willimsky, Stefan B. Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 378–389.
https://doi.org/10.1158/1078-0432.CCR-21-1881
Published: 15 January 2022
View articletitled, T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas
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Includes: Supplementary data
Journal Articles

Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

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Alberto Delaidelli, Christopher Dunham, Mariarita Santi, Gian Luca Negri, Joanna Triscott, Olga Zheludkova, Andrey Golanov, Marina Ryzhova, Konstantin Okonechnikov, Daniel Schrimpf, Damian Stichel, David W. Ellison, Andreas von Deimling, Marcel Kool, Stefan M. Pfister, Vijay Ramaswamy, Andrey Korshunov, Michael D. Taylor, Poul H. Sorensen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 116–128.
https://doi.org/10.1158/1078-0432.CCR-21-2057
Published: 05 January 2022
View articletitled, Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study
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Includes: Supplementary data
Journal Articles

Surfactant Expression Defines an Inflamed Subtype of Lung Adenocarcinoma Brain Metastases that Correlates with Prolonged Survival

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Kolja Pocha, Andreas Mock, Carmen Rapp, Steffen Dettling, Rolf Warta, Christoph Geisenberger, Christine Jungk, Leila R. Martins, Niels Grabe, David Reuss, Juergen Debus, Andreas von Deimling, Amir Abdollahi, Andreas Unterberg, Christel C. Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (9): 2231–2243.
https://doi.org/10.1158/1078-0432.CCR-19-2184
Published: 01 May 2020
View articletitled, Surfactant Expression Defines an Inflamed Subtype of Lung Adenocarcinoma Brain Metastases that Correlates with Prolonged Survival
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Includes: Supplementary data
Journal Articles

DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas

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Marije E. Weidema, Ellen van de Geer, Christian Koelsche, Ingrid M.E. Desar, Patrick Kemmeren, Melissa H.S. Hillebrandt-Roeffen, Vincent K.Y. Ho, Winette T.A. van der Graaf, Yvonne M.H. Versleijen-Jonkers, Andreas von Deimling, Uta E. Flucke
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 93–100.
https://doi.org/10.1158/1078-0432.CCR-19-2180
Published: 03 January 2020
View articletitled, DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas
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Includes: Supplementary data
Journal Articles

Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas

Free
Carmen Rapp, Steffen Dettling, Fang Liu, Anna Theresa Ull, Rolf Warta, Christine Jungk, Saskia Roesch, Andreas Mock, Felix Sahm, Melissa Schmidt, Gerhard Jungwirth, Klaus Zweckberger, Katrin Lamszus, Konstaninos Gousias, Almuth F. Kessler, Niels Grabe, Mario Loehr, Ralf Ketter, Steffi Urbschat, Christian Senft, Manfred Westphal, Amir Abdollahi, Juergen Debus, Andreas von Deimling, Andreas Unterberg, Matthias Simon, Christel C. Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (17): 5260–5270.
https://doi.org/10.1158/1078-0432.CCR-19-0389
Published: 03 September 2019
View articletitled, Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas
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Includes: Supplementary data
Journal Articles

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

Free
Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Ridinger, Dennis Riehl, Diren Usta, Britta Ismer, Alexander C. Sommerkamp, J.P. Martinez-Barbera, Annika K. Wefers, Marc Remke, Daniel Picard, Stefan Pusch, Jan Gronych, Ina Oehme, Cornelis M. van Tilburg, Marcel Kool, Daniela Kuhn, David Capper, Andreas von Deimling, Martin U. Schuhmann, Christel Herold-Mende, Andrey Korshunov, Tilman Brummer, Stefan M. Pfister, David T.W. Jones, Olaf Witt, Till Milde
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1851–1866.
https://doi.org/10.1158/1078-0432.CCR-18-1965
Published: 15 March 2019
View articletitled, The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma
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Includes: Supplementary data
Journal Articles

Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib

Free
Anne Berberich, Tobias Kessler, Carina M. Thomé, Stefan Pusch, Thomas Hielscher, Felix Sahm, Iris Oezen, Lara-Marie Schmitt, Sara Ciprut, Nanina Hucke, Petra Ruebmann, Manuel Fischer, Dieter Lemke, Michael O. Breckwoldt, Andreas von Deimling, Martin Bendszus, Michael Platten, Wolfgang Wick
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 253–265.
https://doi.org/10.1158/1078-0432.CCR-18-1580
Published: 03 January 2019
View articletitled, Targeting Resistance against the MDM2 Inhibitor RG7388 in Glioblastoma Cells by the MEK Inhibitor Trametinib
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Includes: Supplementary data
Journal Articles

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling

Free
Klaus G. Griewank, Christian Koelsche, Johannes A.P. van de Nes, Daniel Schrimpf, Marco Gessi, Inga Möller, Antje Sucker, Richard A. Scolyer, Michael E. Buckland, Rajmohan Murali, Torsten Pietsch, Andreas von Deimling, Dirk Schadendorf
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (18): 4494–4504.
https://doi.org/10.1158/1078-0432.CCR-18-0763
Published: 14 September 2018
View articletitled, Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling
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Includes: Supplementary data
Journal Articles

Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma

Free
Steffen Dettling, Slava Stamova, Rolf Warta, Martina Schnölzer, Carmen Rapp, Anchana Rathinasamy, David Reuss, Kolja Pocha, Saskia Roesch, Christine Jungk, Uwe Warnken, Volker Eckstein, Niels Grabe, Christoph Schramm, Markus A. Weigand, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (12): 2951–2962.
https://doi.org/10.1158/1078-0432.CCR-17-1839
Published: 14 June 2018
View articletitled, Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma
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Includes: Supplementary data
Journal Articles

Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors

Free
Jörg Felsberg, Bettina Hentschel, Kerstin Kaulich, Dorothee Gramatzki, Angela Zacher, Bastian Malzkorn, Marcel Kamp, Michael Sabel, Matthias Simon, Manfred Westphal, Gabriele Schackert, Jörg C. Tonn, Torsten Pietsch, Andreas von Deimling, Markus Loeffler, Guido Reifenberger, Michael Weller
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (22): 6846–6855.
https://doi.org/10.1158/1078-0432.CCR-17-0890
Published: 14 November 2017
View articletitled, Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors
Open the PDF for Epidermal Growth Factor Receptor Variant III (EGFRvIII) Positivity in EGFR-Amplified Glioblastomas: Prognostic Role and Comparison between Primary and Recurrent Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management

Free
Kasthuri S. Kannan, Aristotelis Tsirigos, Jonathan Serrano, Lynn Ann Forrester, Arline Faustin, Cheddhi Thomas, David Capper, Volker Hovestadt, Stefan M. Pfister, David T. W Jones, Martin Sill, Daniel Schrimpf, Andreas von Deimling, Adriana Heguy, Sharon L. Gardner, Jeffrey Allen, Cyrus Hedvat, David Zagzag, Matija Snuderl, Matthias A. Karajannis
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (1_Supplement): 11.
https://doi.org/10.1158/1557-3265.PMSCLINGEN15-11
Published: 03 January 2016
View articletitled, Abstract 11: Advancing methylation profiling in neuropathology: Diagnosis and clinical management
Journal Articles

A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma

Free
Wolfgang Wick, Harald Fricke, Klaus Junge, Grigory Kobyakov, Tobias Martens, Oliver Heese, Benedikt Wiestler, Maximilian G. Schliesser, Andreas von Deimling, Josef Pichler, Elena Vetlova, Inga Harting, Jürgen Debus, Christian Hartmann, Claudia Kunz, Michael Platten, Martin Bendszus, Stephanie E. Combs
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6304–6313.
https://doi.org/10.1158/1078-0432.CCR-14-0951-T
Published: 14 December 2014
View articletitled, A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma
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Includes: Supplementary data
Journal Articles

Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations

Free
Christian Hartmann, Bettina Hentschel, Matthias Simon, Manfred Westphal, Gabriele Schackert, Jörg C. Tonn, Markus Loeffler, Guido Reifenberger, Torsten Pietsch, Andreas von Deimling, Michael Weller, for the German Glioma Network
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (18): 5146–5157.
https://doi.org/10.1158/1078-0432.CCR-13-0017
Published: 16 September 2013
View articletitled, Long-Term Survival in Primary Glioblastoma With Versus Without Isocitrate Dehydrogenase Mutations
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Includes: Supplementary data
Journal Articles

Molecular Markers in Low-Grade Gliomas: Predictive or Prognostic?

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Christian Hartmann, Bettina Hentschel, Marcos Tatagiba, Johannes Schramm, Oliver Schnell, Clemens Seidel, Robert Stein, Guido Reifenberger, Torsten Pietsch, Andreas von Deimling, Markus Loeffler, Michael Weller
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4588–4599.
https://doi.org/10.1158/1078-0432.CCR-10-3194
Published: 05 July 2011
View articletitled, Molecular Markers in Low-Grade Gliomas: Predictive or Prognostic?
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Includes: Supplementary data
Journal Articles

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

Free
Jennifer Lohr, Thomas Ratliff, Andrea Huppertz, Yingzi Ge, Christine Dictus, Rezvan Ahmadi, Stefan Grau, Nobuyoshi Hiraoka, Volker Eckstein, Rupert C. Ecker, Thomas Korff, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4296–4308.
https://doi.org/10.1158/1078-0432.CCR-10-2557
Published: 05 July 2011
View articletitled, Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β
Open the PDF for Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β in another window
Includes: Supplementary data
Journal Articles

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

Free
Till Milde, Ina Oehme, Andrey Korshunov, Annette Kopp-Schneider, Marc Remke, Paul Northcott, Hedwig E. Deubzer, Marco Lodrini, Michael D. Taylor, Andreas von Deimling, Stefan Pfister, Olaf Witt
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (12): 3240–3252.
https://doi.org/10.1158/1078-0432.CCR-10-0395
Published: 14 June 2010
View articletitled, HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth
Open the PDF for HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth in another window
Includes: Supplementary data