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Amar Gajjar
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Journal Articles

Abstract B012: M-PACT: Methylation-based predictive algorithm for CNS tumor liquid biopsies

Tom T. Fischer, Kyle S. Smith, Katie Han, Anna Kostecka, Hong Lin, Daniel Senfter, Tatjana Wedig, Nathalie Schwarz, Natalia Stepien, Sibylle Madlener, Christine Haberler, Esther Hulleman, Sandeep K. Dhanda, Stefan M. Pfister, Santhosh Upadhyaya, Amar Gajjar, Giles W. Robinson, Joonas Haapasalo, Hannu Haapasalo, Kristiina Nordfors, Johannes Gojo, Kendra K. Maass, Kristian W. Pajtler, Paul A. Northcott
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B012.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B012
Published: 13 November 2024
View articletitled, Abstract B012: M-PACT: Methylation-based predictive algorithm for CNS tumor liquid biopsies
Journal Articles

Verschlimmbesserung: Craniospinal Radiotherapy Is Essential in WNT Medulloblastoma Patients

Nicholas G. Gottardo, Amar Gajjar
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (24): 4996–4998.
https://doi.org/10.1158/1078-0432.CCR-23-2331
Published: 15 December 2023
View articletitled, Verschlimmbesserung: Craniospinal Radiotherapy Is Essential in WNT Medulloblastoma Patients
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Journal Articles

Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials

Santhosh A. Upadhyaya, Giles W. Robinson, Arzu Onar-Thomas, Brent A. Orr, Pascal Johann, Gang Wu, Catherine A. Billups, Ruth G. Tatevossian, Sandeep Kumar Dhanda, Ashok Srinivasan, Alberto Broniscer, Ibrahim Qaddoumi, Anna Vinitsky, Gregory T. Armstrong, Anne E. Bendel, Tim Hassall, Sonia Partap, Paul G. Fisher, John R. Crawford, Murali Chintagumpala, Eric Bouffet, Sridharan Gururangan, Roya Mostafavi, Robert P. Sanders, Paul Klimo, Jr, Zoltan Patay, Daniel J. Indelicato, Kim E. Nichols, Frederick A. Boop, Thomas E. Merchant, Marcel Kool, David W. Ellison, Amar Gajjar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2879–2889.
https://doi.org/10.1158/1078-0432.CCR-20-4731
Published: 15 May 2021
View articletitled, Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials
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Includes: Supplementary data
Journal Articles

Abstract PO-077: Image clustering of brain tumor patients using a deep neural network

Hadi Hosseini, Cheng Cheng, John Glass, Gene Reddick, Amar Gajjar, Zhaohua Lu
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5_Supplement): PO-077.
https://doi.org/10.1158/1557-3265.ADI21-PO-077
Published: 01 March 2021
View articletitled, Abstract PO-077: Image clustering of brain tumor patients using a deep neural network
Journal Articles

Exposure–Toxicity Association of Cyclophosphamide and Its Metabolites in Infants and Young Children with Primary Brain Tumors: Implications for Dosing

Olivia Campagne, Bo Zhong, Sreenath Nair, Tong Lin, Jie Huang, Arzu Onar-Thomas, Giles Robinson, Amar Gajjar, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1563–1573.
https://doi.org/10.1158/1078-0432.CCR-19-2685
Published: 01 April 2020
View articletitled, Exposure–Toxicity Association of Cyclophosphamide and Its Metabolites in Infants and Young Children with Primary Brain Tumors: Implications for Dosing
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Includes: Supplementary data
Journal Articles

Establishing a Preclinical Multidisciplinary Board for Brain Tumors

Birgit V. Nimmervoll, Nidal Boulos, Brandon Bianski, Jason Dapper, Michael DeCuypere, Anang Shelat, Sabrina Terranova, Hope E. Terhune, Amar Gajjar, Yogesh T. Patel, Burgess B. Freeman, Arzu Onar-Thomas, Clinton F. Stewart, Martine F. Roussel, R. Kipling Guy, Thomas E. Merchant, Christopher Calabrese, Karen D. Wright, Richard J. Gilbertson
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (7): 1654–1666.
https://doi.org/10.1158/1078-0432.CCR-17-2168
Published: 02 April 2018
View articletitled, Establishing a Preclinical Multidisciplinary Board for Brain Tumors
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Includes: Supplementary data
Journal Articles

Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy

Amar Gajjar, Stefan M. Pfister, Michael D. Taylor, Richard J. Gilbertson
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (22): 5630–5640.
https://doi.org/10.1158/1078-0432.CCR-14-0833
Published: 13 November 2014
View articletitled, Molecular Insights into Pediatric Brain Tumors Have the Potential to Transform Therapy
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Journal Articles

Phase I Study of Vismodegib in Children with Recurrent or Refractory Medulloblastoma: A Pediatric Brain Tumor Consortium Study

Amar Gajjar, Clinton F. Stewart, David W. Ellison, Sue Kaste, Larry E. Kun, Roger J. Packer, Stewart Goldman, Murali Chintagumpala, Dana Wallace, Naoko Takebe, James M. Boyett, Richard J. Gilbertson, Tom Curran
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (22): 6305–6312.
https://doi.org/10.1158/1078-0432.CCR-13-1425
Published: 14 November 2013
View articletitled, Phase I Study of Vismodegib in Children with Recurrent or Refractory Medulloblastoma: A Pediatric Brain Tumor Consortium Study
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Includes: Supplementary data
Journal Articles

Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Alberto Broniscer, Sharyn D. Baker, Cynthia Wetmore, Atmaram S. Pai Panandiker, Jie Huang, Andrew M. Davidoff, Arzu Onar-Thomas, John C. Panetta, Thomas K. Chin, Thomas E. Merchant, Justin N. Baker, Sue C. Kaste, Amar Gajjar, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (11): 3050–3058.
https://doi.org/10.1158/1078-0432.CCR-13-0306
Published: 30 May 2013
View articletitled, Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma
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Includes: Supplementary data
Journal Articles

Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma

Trevor McKibbin, John C. Panetta, Maryam Fouladi, Amar Gajjar, Feng Bai, M. Fatih Okcu, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (3): 1049–1057.
https://doi.org/10.1158/1078-0432.CCR-09-1997
Published: 01 February 2010
View articletitled, Clinical Pharmacokinetics of Amifostine and WR1065 in Pediatric Patients with Medulloblastoma
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Includes: Supplementary data
Journal Articles

Phase I and Pharmacokinetic Studies of Erlotinib Administered Concurrently with Radiotherapy for Children, Adolescents, and Young Adults with High-Grade Glioma

Alberto Broniscer, Suzanne J. Baker, Clinton F. Stewart, Thomas E. Merchant, Fred H. Laningham, Paula Schaiquevich, Mehmet Kocak, E. Brannon Morris, Raelene Endersby, David W. Ellison, Amar Gajjar
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (2): 701–707.
https://doi.org/10.1158/1078-0432.CCR-08-1923
Published: 15 January 2009
View articletitled, Phase I and Pharmacokinetic Studies of Erlotinib Administered Concurrently with Radiotherapy for Children, Adolescents, and Young Adults with High-Grade Glioma
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Journal Articles

Population Pharmacokinetic Analysis of Topotecan in Pediatric Cancer Patients

Paula Schaiquevich, John C. Panetta, Lisa C. Iacono, Burgess B. Freeman, III, Victor M. Santana, Amar Gajjar, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22): 6703–6711.
https://doi.org/10.1158/1078-0432.CCR-07-1376
Published: 15 November 2007
View articletitled, Population Pharmacokinetic Analysis of Topotecan in Pediatric Cancer Patients
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Includes: Supplementary data
Journal Articles

Phase I Trial of Single-Dose Temozolomide and Continuous Administration of O6-Benzylguanine in Children with Brain Tumors: a Pediatric Brain Tumor Consortium Report

Alberto Broniscer, Sridharan Gururangan, Tobey J. MacDonald, Stewart Goldman, Roger J. Packer, Clinton F. Stewart, Dana Wallace, Mary K. Danks, Henry S. Friedman, Tina Y. Poussaint, Larry E. Kun, James M. Boyett, Amar Gajjar, for the Pediatric Brain Tumor Consortium
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22): 6712–6718.
https://doi.org/10.1158/1078-0432.CCR-07-1016
Published: 15 November 2007
View articletitled, Phase I Trial of Single-Dose Temozolomide and Continuous Administration of O6-Benzylguanine in Children with Brain Tumors: a Pediatric Brain Tumor Consortium Report
Open the PDF for Phase I Trial of Single-Dose Temozolomide and Continuous Administration of O6-Benzylguanine in Children with Brain Tumors: a Pediatric Brain Tumor Consortium Report in another window
Includes: Supplementary data
Journal Articles

Plasma and Cerebrospinal Fluid Pharmacokinetics of Erlotinib and Its Active Metabolite OSI-420

Alberto Broniscer, John C. Panetta, Melinda O'Shaughnessy, Charles Fraga, Feng Bai, Matthew J. Krasin, Amar Gajjar, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (5): 1511–1515.
https://doi.org/10.1158/1078-0432.CCR-06-2372
Published: 01 March 2007
View articletitled, Plasma and Cerebrospinal Fluid Pharmacokinetics of Erlotinib and Its Active Metabolite OSI-420
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Journal Articles

ERBB1 Is Amplified and Overexpressed in High-grade Diffusely Infiltrative Pediatric Brain Stem Glioma

Richard J. Gilbertson, D. Ashley Hill, Roberto Hernan, Mehmet Kocak, Russell Geyer, Jim Olson, Amar Gajjar, Lisa Rush, Ronald L. Hamilton, Sydney D. Finkelstein, Ian F. Pollack
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3620–3624.
Published: 23 September 2003
View articletitled, ERBB1 Is Amplified and Overexpressed in High-grade Diffusely Infiltrative Pediatric Brain Stem Glioma
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Journal Articles

A Pilot Study of Protracted Topotecan Dosing Using a Pharmacokinetically Guided Dosing Approach in Children with Solid Tumors

Victor M. Santana, William C. Zamboni, Mark N. Kirstein, Ming Tan, Tiebin Liu, Amar Gajjar, Peter J. Houghton, Clinton F. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 633–640.
Published: 01 February 2003
View articletitled, A Pilot Study of Protracted Topotecan Dosing Using a Pharmacokinetically Guided Dosing Approach in Children with Solid Tumors
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Journal Articles

Altered Irinotecan Pharmacokinetics in Pediatric High-Grade Glioma Patients Receiving Enzyme-inducing Anticonvulsant Therapy

Kristine R. Crews, Clinton F. Stewart, Dana Jones-Wallace, Stephen J. Thompson, Peter J. Houghton, Richard L. Heideman, Maryam Fouladi, Daniel C. Bowers, Murali M. Chintagumpala, Amar Gajjar
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (7): 2202–2209.
Published: 01 July 2002
View articletitled, Altered Irinotecan Pharmacokinetics in Pediatric High-Grade Glioma Patients Receiving Enzyme-inducing Anticonvulsant Therapy
Open the PDF for Altered Irinotecan Pharmacokinetics in Pediatric High-Grade Glioma Patients Receiving Enzyme-inducing Anticonvulsant Therapy in another window