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Alexandre Reuben
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Journal Articles

Maintenance Pembrolizumab Therapy in Patients with Metastatic HER2-negative Breast Cancer with Prior Response to Chemotherapy

Toshiaki Iwase, Evan N. Cohen, Hui Gao, Angela Alexander, Megumi Kai, Vivian Chiv, Xiaoping Wang, Savitri Krishnamurthy, Diane Liu, Yu Shen, Kumiko Kida, Alexandre Reuben, Rachel M. Layman, David L. Ramirez, Debasish Tripathy, Stacy L. Moulder, Clinton Yam, Vicente Valero, Bora Lim, James M. Reuben, Naoto T. Ueno
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (11): 2424–2432.
https://doi.org/10.1158/1078-0432.CCR-23-2947
Published: 03 June 2024
View article titled, Maintenance Pembrolizumab Therapy in Patients with Metastatic HER2-negative Breast Cancer with Prior Response to Chemotherapy
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Includes: Supplementary data
Journal Articles

T-Cell Receptor Repertoire Sequencing in the Era of Cancer Immunotherapy

Meredith L. Frank, Kaylene Lu, Can Erdogan, Yi Han, Jian Hu, Tao Wang, John V. Heymach, Jianjun Zhang, Alexandre Reuben
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (6): 994–1008.
https://doi.org/10.1158/1078-0432.CCR-22-2469
Published: 14 March 2023
View article titled, T-Cell Receptor Repertoire Sequencing in the Era of Cancer Immunotherapy
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Journal Articles

Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment

Runzhe Chen, Won-Chul Lee, Junya Fujimoto, Jun Li, Xin Hu, Reza Mehran, David Rice, Stephen G. Swisher, Boris Sepesi, Hai T. Tran, Chi-Wan Chow, Latasha D. Little, Curtis Gumbs, Cara Haymaker, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Jianhua Zhang, Alexandre Reuben, Anne S. Tsao, Jianjun Zhang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5477–5486.
https://doi.org/10.1158/1078-0432.CCR-20-1767
Published: 15 October 2020
View article titled, Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment
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Includes: Supplementary data
Journal Articles

Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy

Feng Xie, Jianjun Zhang, Jiayin Wang, Alexandre Reuben, Wei Xu, Xin Yi, Frederick S. Varn, Yongsheng Ye, Junwen Cheng, Miao Yu, Yue Wang, Yufeng Liu, Mingchao Xie, Peng Du, Ke Ma, Xin Ma, Penghui Zhou, Shengli Yang, Yaobing Chen, Guoping Wang, Xuefeng Xia, Zhongxing Liao, John V. Heymach, Ignacio I. Wistuba, P. Andrew Futreal, Kai Ye, Chao Cheng, Tian Xia
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12): 2908–2920.
https://doi.org/10.1158/1078-0432.CCR-19-1744
Published: 15 June 2020
View article titled, Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy
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Includes: Supplementary data
Journal Articles

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

Emily Z. Keung, Melissa Burgess, Ruth Salazar, Edwin R. Parra, Jaime Rodrigues-Canales, Vanessa Bolejack, Brian A. Van Tine, Scott M. Schuetze, Steven Attia, Richard F. Riedel, James Hu, Scott H. Okuno, Dennis A. Priebat, Sujana Movva, Lara E. Davis, Damon R. Reed, Alexandre Reuben, Christina L. Roland, Denise Reinke, Alexander J. Lazar, Wei-Lien Wang, Jennifer A. Wargo, Hussein A. Tawbi
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1258–1266.
https://doi.org/10.1158/1078-0432.CCR-19-1824
Published: 13 March 2020
View article titled, Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab
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Includes: Supplementary data
Journal Articles

A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma

Y.N. Vashisht Gopal, Seth Gammon, Rishika Prasad, Barbara Knighton, Federica Pisaneschi, Jason Roszik, Ningping Feng, Sarah Johnson, Snigdha Pramanik, Jessica Sudderth, Dawen Sui, Courtney Hudgens, Grant M. Fischer, Wanleng Deng, Alexandre Reuben, Weiyi Peng, Jian Wang, Jennifer L. McQuade, Michael T. Tetzlaff, Maria E. Di Francesco, Joe Marszalek, David Piwnica-Worms, Ralph J. DeBerardinis, Michael A. Davies
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (21): 6429–6442.
https://doi.org/10.1158/1078-0432.CCR-19-0836
Published: 01 November 2019
View article titled, A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma
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Includes: Supplementary data
Journal Articles

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?

Alexandria P. Cogdill, Peter A. Prieto, Alexandre Reuben, Jennifer A. Wargo
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (2): 327–329.
https://doi.org/10.1158/1078-0432.CCR-16-2493
Published: 15 January 2017
View article titled, Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?
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Journal Articles

Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma

Laurence Feldmeyer, Courtney W. Hudgens, Genevieve Ray-Lyons, Priyadharsini Nagarajan, Phyu P. Aung, Jonathan L. Curry, Carlos A. Torres-Cabala, Barbara Mino, Jaime Rodriguez-Canales, Alexandre Reuben, Pei-Ling Chen, Jennifer S. Ko, Steven D. Billings, Roland L. Bassett, Ignacio I. Wistuba, Zachary A. Cooper, Victor G. Prieto, Jennifer A. Wargo, Michael T. Tetzlaff
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (22): 5553–5563.
https://doi.org/10.1158/1078-0432.CCR-16-0392
Published: 14 November 2016
View article titled, Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

Zachary A. Cooper, Alexandre Reuben, Jacob Austin-Breneman, Jennifer A. Wargo
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (14): 3102–3104.
https://doi.org/10.1158/1078-0432.CCR-15-0363
Published: 14 July 2015
View article titled, Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy
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