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Alexander N. Shoushtari
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Journal Articles

Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti–PD-1 Monotherapy

Xue Bai, Jiani Hu, Allison Betof Warner, Henry T. Quach, Christopher G. Cann, Michael Z. Zhang, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoling Yang, Xiaoting Wei, Lalit Pallan, Catriona Harvey, Michael P. Manos, Olivia Ouyang, Michelle S. Kim, Gyulnara Kasumova, Justine V. Cohen, Donald P. Lawrence, Christine Freedman, Riley M. Fadden, Krista M. Rubin, Tatyana Sharova, Dennie T. Frederick, Keith T. Flaherty, Osama E. Rahma, Georgina V. Long, Alexander M. Menzies, Jun Guo, Alexander N. Shoushtari, Douglas B. Johnson, Ryan J. Sullivan, Genevieve M. Boland
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5993–6000.
DOI: https://doi.org/10.1158/1078-0432.CCR-21-1283
Published: 01 November 2021
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Journal Articles

Therapeutic Implications of Detecting MAPK-Activating Alterations in Cutaneous and Unknown Primary Melanomas

Alexander N. Shoushtari, Walid K. Chatila, Arshi Arora, Francisco Sanchez-Vega, Havish S. Kantheti, Jorge A. Rojas Zamalloa, Penina Krieger, Margaret K. Callahan, Allison Betof Warner, Michael A. Postow, Parisa Momtaz, Suresh Nair, Charlotte E. Ariyan, Christopher A. Barker, Mary Susan Brady, Daniel G. Coit, Neal Rosen, Paul B. Chapman, Klaus J. Busam, David B. Solit, Katherine S. Panageas, Jedd D. Wolchok, Nikolaus Schultz
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2226–2235.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-4189
Published: 15 April 2021
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Journal Articles

Combined Inhibition of Gαq and MEK Enhances Therapeutic Efficacy in Uveal Melanoma

Tyler D. Hitchman, Gabriella Bayshtok, Emilie Ceraudo, Amanda R. Moore, Cindy Lee, Ruobing Jia, Naitao Wang, Mohini R. Pachai, Alexander N. Shoushtari, Jasmine H. Francis, Youxin Guan, Juliet Chen, Matthew T. Chang, Barry S. Taylor, Thomas P. Sakmar, Thomas Huber, Ping Chi, Yu Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5): 1476–1490.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-2860
Published: 01 March 2021
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Journal Articles

Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

Mark R. Middleton, Cheryl McAlpine, Victoria K. Woodcock, Pippa Corrie, Jeffrey R. Infante, Neil M. Steven, Thomas R. Jeffry Evans, Alan Anthoney, Alexander N. Shoushtari, Omid Hamid, Avinash Gupta, Antonella Vardeu, Emma Leach, Revashnee Naidoo, Sarah Stanhope, Sion Lewis, Jacob Hurst, Ita O’Kelly, Mario Sznol
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (22): 5869–5878.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-1247
Published: 13 November 2020
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Includes: Supplementary data
Journal Articles

PD-1 Blockade in Chinese versus Western Patients with Melanoma

Alexander N. Shoushtari, Riyue Bao, Jason J. Luke
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4171–4173.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-1558
Published: 14 August 2020
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Journal Articles

A Prospective, Phase 1 Trial of Nivolumab, Ipilimumab, and Radiotherapy in Patients with Advanced Melanoma

Michael A. Postow, Susan J. Knox, Debra A. Goldman, Yuval Elhanati, Vikram Mavinkurve, Phillip Wong, Darragh Halpenny, Sunil K. Reddy, Kenya Vado, Danielle McCabe, Kristen Aufiero Ramirez, Mary Macri, Paul Schwarzenberger, Toni Ricciardi, Aileen Ryan, Ralph Venhaus, Parisa Momtaz, Alexander N. Shoushtari, Margaret K. Callahan, Paul B. Chapman, Jedd D. Wolchok, Priyanka B. Subrahmanyam, Holden T. Maecker, Katherine S. Panageas, Christopher A. Barker
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3193–3201.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-3936
Published: 01 July 2020
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About Face: Molecular Aberrations in Head and Neck Mucosal Melanomas

Alexander N. Shoushtari
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (12): 3473–3475.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-0658
Published: 14 June 2019
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Journal Articles

Rates of ERBB2 Alterations across Melanoma Subtypes and a Complete Response to Trastuzumab Emtansine in an ERBB2-Amplified Acral Melanoma

Lee S. Gottesdiener, Shannon O'Connor, Klaus J. Busam, Helen Won, David B. Solit, David M. Hyman, Alexander N. Shoushtari
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (23): 5815–5819.
DOI: https://doi.org/10.1158/1078-0432.CCR-18-1397
Published: 03 December 2018
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Journal Articles

Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab

Sandra P. D'Angelo, Alexander N. Shoushtari, Mary Louise Keohan, Mark A. Dickson, Mrinal M. Gounder, Ping Chi, Jennifer K. Loo, Leigh Gaffney, Lee Schneider, Zarine Patel, Joseph Patrick Erinjeri, Mark J. Bluth, Ana Sjoberg, Howard Streicher, Naoko Takebe, Li-Xuan Qin, Cristina Antonescu, Ronald P. DeMatteo, Richard D. Carvajal, William D. Tap
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (12): 2972–2980.
DOI: https://doi.org/10.1158/1078-0432.CCR-16-2349
Published: 14 June 2017
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Includes: Supplementary data