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Journal Articles

Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study

Clin Cancer Res OF1–OF13.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-4504

Published: 18 February 2022

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Includes: Supplementary data

Journal Articles

Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma

Kate Lynn J. Bill, Jeannine Garnett, Isabelle Meaux, XiaoYen Ma, Chad J. Creighton, Svetlana Bolshakov, Cedric Barriere, Laurent Debussche, Alexander J. Lazar, Bethany C. Prudner, Lucia Casadei, Danielle Braggio, Gonzalo Lopez, Abbie Zewdu, Hemant Bid, Lev Dina, Raphael E. Pollock

Clin Cancer Res (2022) 28 (2): 431.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-4243

Published: 19 January 2022

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Journal Articles

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

Clin Cancer Res (2020) 26 (6): 1258–1266.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-1824

Published: 13 March 2020

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Includes: Supplementary data

Journal Articles

B7-H3 Expression in Merkel Cell Carcinoma–Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

Phyu P. Aung, Edwin Roger Parra, Souptik Barua, Dawen Sui, Jing Ning, Barbara Mino, Debora Alejandra Ledesma, Jonathan L. Curry, Priyadharsini Nagarajan, Carlos A. Torres-Cabala, Eleni Efstathiou, Anh G. Hoang, Michael K. Wong, Jennifer A. Wargo, Alexander J. Lazar, Arvind Rao, Victor G. Prieto, Ignacio Wistuba, Michael T. Tetzlaff

Clin Cancer Res (2019) 25 (11): 3455–3467.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-2355

Published: 03 June 2019

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Includes: Supplementary data

Journal Articles

Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival

Clin Cancer Res (2018) 24 (19): 4865–4873.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0202

Published: 01 October 2018

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Includes: Supplementary data

Journal Articles

Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma

Vladimir Bezrookove, Mehdi Nosrati, James R. Miller, III, David De Semir, Altaf A. Dar, Elham Vosoughi, Edith Vaquero, Antje Sucker, Alexander J. Lazar, Jeffrey E. Gershenwald, Michael A. Davies, Dirk Schadendorf, Mohammed Kashani-Sabet

Clin Cancer Res (2018) 24 (17): 4119–4125.

DOI: https://doi.org/10.1158/1078-0432.CCR-18-0791

Published: 04 September 2018

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Includes: Supplementary data

Journal Articles

Abstract PR11: SSX-mediated chromatin engagement and targeting of BAF complexes activates oncogenic transcription in synovial sarcoma

Matthew J. McBride, John L. Pulice, Robert T. Nakayama, Nazar Mashtalir, Davis R. Ingram, Jacob D. Jaffe, Jack F. Shern, Javed Khan, Jason L. Hornick, Alexander J. Lazar, Cigall Kadoch

Clin Cancer Res (2018) 24 (2_Supplement): PR11.

DOI: https://doi.org/10.1158/1557-3265.SARCOMAS17-PR11

Published: 15 January 2018

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Journal Articles

SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma

Clin Cancer Res (2016) 22 (5): 1150–1160.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-1522

Published: 01 March 2016

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Includes: Supplementary data

Journal Articles

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

Rashmi S. Goswami, Keyur P. Patel, Rajesh R. Singh, Funda Meric-Bernstam, E. Scott Kopetz, Vivek Subbiah, Ricardo H. Alvarez, Michael A. Davies, Kausar J. Jabbar, Sinchita Roy-Chowdhuri, Alexander J. Lazar, L. Jeffrey Medeiros, Russell R. Broaddus, Rajyalakshmi Luthra, Mark J. Routbort

Clin Cancer Res (2015) 21 (11): 2644–2651.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-2391

Published: 31 May 2015

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Includes: Supplementary data

Journal Articles

New, Tolerable γ-Secretase Inhibitor Takes Desmoid Down a Notch

Dennis P.M. Hughes, Shivaani Kummar, Alexander J. Lazar

Clin Cancer Res (2015) 21 (1): 7–9.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-1660

Published: 05 January 2015

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Journal Articles

Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Goncalves Pereira, Wanleng Deng, Ju-Seog Lee, Katherine L. Nathanson, Kenneth D. Aldape, Victor G. Prieto, Darrin Stuart, Michael A. Davies

Clin Cancer Res (2014) 20 (21): 5537–5546.

DOI: https://doi.org/10.1158/1078-0432.CCR-13-3003

Published: 30 October 2014

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Includes: Supplementary data

Journal Articles

Complete Loss of PTEN Protein Expression Correlates with Shorter Time to Brain Metastasis and Survival in Stage IIIB/C Melanoma Patients with BRAF^V600 Mutations

Amanda D. Bucheit, Guo Chen, Alan Siroy, Michael Tetzlaff, Russell Broaddus, Denai Milton, Patricia Fox, Roland Bassett, Patrick Hwu, Jeffrey E. Gershenwald, Alexander J. Lazar, Michael A. Davies

Clin Cancer Res (2014) 20 (21): 5527–5536.

DOI: https://doi.org/10.1158/1078-0432.CCR-14-1027

Published: 30 October 2014

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Includes: Supplementary data

Journal Articles

Dual Targeting of mTOR and Aurora-A Kinase for the Treatment of Uterine Leiomyosarcoma

Kari J. Brewer Savannah, Elizabeth G. Demicco, Kristelle Lusby, Markus PH. Ghadimi, Roman Belousov, Eric Young, Yiqun Zhang, Kai-Lieh Huang, Alexander J. Lazar, Kelly K. Hunt, Raphael E. Pollock, Chad J. Creighton, Matthew L. Anderson, Dina Lev

Clin Cancer Res (2012) 18 (17): 4633–4645.

DOI: https://doi.org/10.1158/1078-0432.CCR-12-0436

Published: 30 August 2012

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Includes: Supplementary data

Journal Articles

Survivin Is a Viable Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors

Markus P. Ghadimi, Eric D. Young, Roman Belousov, Yiqun Zhang, Gonzalo Lopez, Kristelle Lusby, Christine Kivlin, Elizabeth G. Demicco, Chad J. Creighton, Alexander J. Lazar, Raphael E. Pollock, Dina Lev

Clin Cancer Res (2012) 18 (9): 2545–2557.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-2592

Published: 30 April 2012

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Includes: Supplementary data

Journal Articles

New Strategies in Melanoma: Molecular Testing in Advanced Disease

Scott E. Woodman, Alexander J. Lazar, Kenneth D. Aldape, Michael A. Davies

Clin Cancer Res (2012) 18 (5): 1195–1200.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-2317

Published: 01 March 2012

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Journal Articles

Phase I Study of the Combination of Sorafenib and Temsirolimus in Patients with Metastatic Melanoma

Clin Cancer Res (2012) 18 (4): 1120–1128.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-2436

Published: 14 February 2012

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Includes: Supplementary data

Journal Articles

Combining EGFR and mTOR Blockade for the Treatment of Epithelioid Sarcoma

Xianbiao Xie, Markus P.H. Ghadimi, Eric D. Young, Roman Belousov, Quan-sheng Zhu, Juehui Liu, Gonzalo Lopez, Chiara Colombo, Tingsheng Peng, David Reynoso, Jason L. Hornick, Alexander J. Lazar, Dina Lev

Clin Cancer Res (2011) 17 (18): 5901–5912.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-0660

Published: 14 September 2011

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Includes: Supplementary data

Journal Articles

Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors

Keila E. Torres, Quan-Sheng Zhu, Katelynn Bill, Gonzalo Lopez, Markus P. Ghadimi, Xianbiao Xie, Eric D. Young, Juehui Liu, Theresa Nguyen, Svetlana Bolshakov, Roman Belousov, Suizhau Wang, Guy Lahat, Jun Liu, Belinda Hernandez, Alexander J. Lazar, Dina Lev

Clin Cancer Res (2011) 17 (12): 3943–3955.

DOI: https://doi.org/10.1158/1078-0432.CCR-11-0193

Published: 15 June 2011

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Includes: Supplementary data

Journal Articles

TRAIL and Doxorubicin Combination Induces Proapoptotic and Antiangiogenic Effects in Soft Tissue Sarcoma In vivo

Suizhao Wang, Wenhong Ren, Jeffery Liu, Guy Lahat, Keila Torres, Gonzalo Lopez, Alexander J. Lazar, Andrea Hayes-Jordan, Kebin Liu, Jim Bankson, John D. Hazle, Dina Lev

Clin Cancer Res (2010) 16 (9): 2591–2604.

DOI: https://doi.org/10.1158/1078-0432.CCR-09-2443

Published: 28 April 2010

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Journal Articles

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

Michael A. Davies, Katherine Stemke-Hale, E. Lin, Carmen Tellez, Wanleng Deng, Yennu N. Gopal, Scott E. Woodman, Tiffany C. Calderone, Zhenlin Ju, Alexander J. Lazar, Victor G. Prieto, Kenneth Aldape, Gordon B. Mills, Jeffrey E. Gershenwald

Clin Cancer Res (2009) 15 (24): 7538–7546.

DOI: https://doi.org/10.1158/1078-0432.CCR-09-1985

Published: 14 December 2009

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Includes: Supplementary data

NARROW

Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective Study

Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

B7-H3 Expression in Merkel Cell Carcinoma–Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival

Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma

Abstract PR11: SSX-mediated chromatin engagement and targeting of BAF complexes activates oncogenic transcription in synovial sarcoma

SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

New, Tolerable γ-Secretase Inhibitor Takes Desmoid Down a Notch

Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

Complete Loss of PTEN Protein Expression Correlates with Shorter Time to Brain Metastasis and Survival in Stage IIIB/C Melanoma Patients with BRAF^V600 Mutations

Dual Targeting of mTOR and Aurora-A Kinase for the Treatment of Uterine Leiomyosarcoma

Survivin Is a Viable Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors

New Strategies in Melanoma: Molecular Testing in Advanced Disease

Phase I Study of the Combination of Sorafenib and Temsirolimus in Patients with Metastatic Melanoma

Combining EGFR and mTOR Blockade for the Treatment of Epithelioid Sarcoma

Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors

TRAIL and Doxorubicin Combination Induces Proapoptotic and Antiangiogenic Effects in Soft Tissue Sarcoma In vivo

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

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