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Journal Articles

Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer

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Andrew T. Lenis, Vignesh Ravichandran, Samantha Brown, Syed M. Alam, Andrew Katims, Hong Truong, Peter A. Reisz, Samantha Vasselman, Barbara Nweji, Karen A. Autio, Michael J. Morris, Susan F. Slovin, Dana Rathkopf, Daniel Danila, Sungmin Woo, Hebert A. Vargas, Vincent P. Laudone, Behfar Ehdaie, Victor Reuter, Maria Arcila, Michael F. Berger, Agnes Viale, Howard I. Scher, Nikolaus Schultz, Anuradha Gopalan, Mark T.A. Donoghue, Irina Ostrovnaya, Konrad H. Stopsack, David B. Solit, Wassim Abida
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3894–3903.
https://doi.org/10.1158/1078-0432.CCR-23-3403
Published: 03 September 2024
View articletitled, Microsatellite Instability, Tumor Mutational Burden, and Response to Immune Checkpoint Blockade in Patients with Prostate Cancer
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Includes: Supplementary data
Journal Articles

Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach

Free
Seyram A. Doe-Tetteh, Sabrina Y. Camp, Dalicia Reales, Jett Crowdis, Anne Marie Noronha, Bernadette Wolff, Tina Alano, Jesse Galle, S. Duygu Selcuklu, Agnes Viale, Nicholas D. Socci, Ying L. Liu, William P. Tew, Carol Aghajanian, Marc Ladanyi, Meng Xiao He, Saud H. AlDubayan, Roei David Mazor, Ofer Shpilberg, Oshrat Hershkovitz-Rokah, Jose A. Riancho, Jose L. Hernandez, M. Carmen Gonzalez-Vela, Justin J. Buthorn, Manda Wilson, Amy E. Webber, Mariko Yabe, Kseniya Petrova-Drus, Marc Rosenblum, Benjamin H. Durham, Omar Abdel-Wahab, Michael F. Berger, Mark T.A. Donoghue, Andrew L. Kung, Julia Glade Bender, Neerav N. Shukla, Samuel A. Funt, Ahmet Dogan, Robert A. Soslow, Hikmat Al-Ahmadie, Darren R. Feldman, Eliezer M. Van Allen, Eli L. Diamond, David B. Solit
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (13): 2445–2455.
https://doi.org/10.1158/1078-0432.CCR-22-3247
Published: 05 July 2023
View articletitled, Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach
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Includes: Supplementary data
Journal Articles

Abstract PO029: Targeting non-canonical Hippo pathway in NRF2-mutant liver cancer

Free
Viraj Sanghvi, Aleksander Rust, Josef Leibold, Scott Lowe, Agnes Viale, John Chodera, Ronald C. Hendrickson, Elisa de Stanchina, Hans-Guido Wendel
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17_Supplement): PO029.
https://doi.org/10.1158/1557-3265.LIVERCA22-PO029
Published: 01 September 2022
View articletitled, Abstract PO029: Targeting non-canonical Hippo pathway in NRF2-mutant liver cancer
Journal Articles

Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer

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Jashodeep Datta, J. Joshua Smith, Walid K. Chatila, John C. McAuliffe, Cyriac Kandoth, Efsevia Vakiani, Timothy L. Frankel, Karuna Ganesh, Isaac Wasserman, Marla Lipsyc-Sharf, Jose Guillem, Garrett M. Nash, Philip B. Paty, Martin R. Weiser, Leonard B. Saltz, Michael F. Berger, William R. Jarnagin, Vinod Balachandran, T. Peter Kingham, Nancy E. Kemeny, Andrea Cercek, Julio Garcia-Aguilar, Barry S. Taylor, Agnes Viale, Rona Yaeger, David B. Solit, Nikolaus Schultz, Michael I. D'Angelica
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (5): 1077–1085.
https://doi.org/10.1158/1078-0432.CCR-19-2390
Published: 02 March 2020
View articletitled, Coaltered Ras/B-raf and TP53 Is Associated with Extremes of Survivorship and Distinct Patterns of Metastasis in Patients with Metastatic Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma

Free
Ju Youn Lee, Michail Schizas, Felipe C. Geyer, Pier Selenica, Salvatore Piscuoglio, Rita A. Sakr, Charlotte K.Y. Ng, Jose V. Scarpa Carniello, Russell Towers, Dilip D. Giri, Victor P. de Andrade, Anastasios D. Papanastasiou, Agnes Viale, Reuben S. Harris, David B. Solit, Britta Weigelt, Jorge S. Reis-Filho, Tari A. King
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (2): 674–686.
https://doi.org/10.1158/1078-0432.CCR-18-1103
Published: 15 January 2019
View articletitled, Lobular Carcinomas In Situ Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma
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Includes: Supplementary data
Journal Articles

Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis

Free
Matthew T. Chang, Alexander Penson, Neil B. Desai, Nicholas D. Socci, Ronglai Shen, Venkatraman E. Seshan, Ritika Kundra, Adam Abeshouse, Agnes Viale, Eugene K. Cha, Xueli Hao, Victor E. Reuter, Charles M. Rudin, Bernard H. Bochner, Jonathan E. Rosenberg, Dean F. Bajorin, Nikolaus Schultz, Michael F. Berger, Gopa Iyer, David B. Solit, Hikmat A. Al-Ahmadie, Barry S. Taylor
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (8): 1965–1973.
https://doi.org/10.1158/1078-0432.CCR-17-2655
Published: 12 April 2018
View articletitled, Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis
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Includes: Supplementary data
Journal Articles

Abstract PR16: Multiplatform analysis of paired primary and recurrent well- and dedifferentiated liposarcoma samples defines copy number alterations as dominant drivers of initiation and progression

Free
Aimee M. Crago, Nicholas D. Socci, Li-Xuan Qin, Fatima Wilder, Rachael O'Connor, Amanda Craig, Willem van Houdt, Nils Weinhold, Cyriac Kandoth, Agnes Viale, Cristina Antonescu, Sam Singer
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2_Supplement): PR16.
https://doi.org/10.1158/1557-3265.SARCOMAS17-PR16
Published: 15 January 2018
View articletitled, Abstract PR16: Multiplatform analysis of paired primary and recurrent well- and dedifferentiated liposarcoma samples defines copy number alterations as dominant drivers of initiation and progression
Journal Articles

Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases

Free
Charlotte K.Y. Ng, Francois-Clement Bidard, Salvatore Piscuoglio, Felipe C. Geyer, Raymond S. Lim, Ino de Bruijn, Ronglai Shen, Fresia Pareja, Samuel H. Berman, Lu Wang, Jean-Yves Pierga, Anne Vincent-Salomon, Agnes Viale, Larry Norton, Brigitte Sigal, Britta Weigelt, Paul Cottu, Jorge S. Reis-Filho
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 4402–4415.
https://doi.org/10.1158/1078-0432.CCR-16-3115
Published: 01 August 2017
View articletitled, Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases
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Includes: Supplementary data
Journal Articles

Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response

Free
Bryan J. Schneider, Manish A. Shah, Kelsey Klute, Allyson Ocean, Elizabeta Popa, Nasser Altorki, Michael Lieberman, Andrew Schreiner, Rhonda Yantiss, Paul J. Christos, Romae Palmer, Daoqi You, Agnes Viale, Pouneh Kermani, Joseph M. Scandura
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11): 2673–2680.
https://doi.org/10.1158/1078-0432.CCR-16-1896
Published: 31 May 2017
View articletitled, Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response
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Includes: Supplementary data
Journal Articles

A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases

Free
Vinod P. Balachandran, Arshi Arora, Mithat Gönen, Hiromichi Ito, Simon Turcotte, Jinru Shia, Agnes Viale, Nikol Snoeren, Sander R. van Hooff, Inne H.M. Borel Rinkes, René Adam, T. Peter Kingham, Peter J. Allen, Ronald P. DeMatteo, William R. Jarnagin, Michael I. D'Angelica
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (10): 2575–2582.
https://doi.org/10.1158/1078-0432.CCR-15-1071
Published: 12 May 2016
View articletitled, A Validated Prognostic Multigene Expression Assay for Overall Survival in Resected Colorectal Cancer Liver Metastases
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Includes: Supplementary data
Journal Articles

Abstract A18: A novel targeted capture and massively parallel sequencing platform for systematic discovery of tyrosine kinase fusions in cancer

Free
Juliann Chmielecki, Martin Peifer, Peilin Jia, Nicholas D. Socci, Katherine Hutchinson, Agnes Viale, Zhongming Zhao, Roman K. Thomas, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7_Supplement): A18.
https://doi.org/10.1158/1078-0432.TCME10-A18
Published: 02 February 2016
View articletitled, Abstract A18: A novel targeted capture and massively parallel sequencing platform for systematic discovery of tyrosine kinase fusions in cancer
Journal Articles

Abstract B14: Molecular characterization of mucinous ovarian carcinoma.

Free
Brooke Schlappe, Jennifer J. Mueller, Narciso Olvera, Fanny Dao, Cyriac Kandoth, Faina Bogomolniy, Agnes Viale, Kety Huberman, Gouri Nanjangud, Yaser Hussein, Barry Taylor, Robert Soslow, Douglas A. Levine
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2_Supplement): B14.
https://doi.org/10.1158/1557-3265.OVCA15-B14
Published: 15 January 2016
View articletitled, Abstract B14: Molecular characterization of mucinous ovarian carcinoma.
Journal Articles

Evaluation of the feasibility of expression microarray analysis in endoscopically obtained biopsies of gastric carcinoma and their clinical applicability

Free
Minaxi Jhawer, Li-Xuan Qin, Hans Gerdes, David Klimstra, Mark Schattner, Agnes Viale, David Kelsen, Manish Shah
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): A48.
Published: 15 August 2014
View articletitled, Evaluation of the feasibility of expression microarray analysis in endoscopically obtained biopsies of gastric carcinoma and their clinical applicability
Journal Articles

Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy

Free
Martin H. Voss, A. Ari Hakimi, Can G. Pham, A. Rose Brannon, Ying-Bei Chen, Luis F. Cunha, Oguz Akin, Han Liu, Shugaku Takeda, Sasinya N. Scott, Nicholas D. Socci, Agnes Viale, Nikolaus Schultz, Chris Sander, Victor E. Reuter, Paul Russo, Emily H. Cheng, Robert J. Motzer, Michael F. Berger, James J. Hsieh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (7): 1955–1964.
https://doi.org/10.1158/1078-0432.CCR-13-2345
Published: 31 March 2014
View articletitled, Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy
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Includes: Supplementary data
Journal Articles

Antitumor Activity of SNX-2112, a Synthetic Heat Shock Protein-90 Inhibitor, in MET-Amplified Tumor Cells with or without Resistance to Selective MET Inhibition

Free
Thomas Bachleitner-Hofmann, Mark Y. Sun, Chin-Tung Chen, David Liska, Zhaoshi Zeng, Agnes Viale, Adam B. Olshen, Martina Mittlboeck, James G. Christensen, Neal Rosen, David B. Solit, Martin R. Weiser
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (1): 122–133.
https://doi.org/10.1158/1078-0432.CCR-10-0253
Published: 04 January 2011
View articletitled, Antitumor Activity of SNX-2112, a Synthetic Heat Shock Protein-90 Inhibitor, in MET-Amplified Tumor Cells with or without Resistance to Selective MET Inhibition
Open the PDF for Antitumor Activity of SNX-2112, a Synthetic Heat Shock Protein-90 Inhibitor, in MET-Amplified Tumor Cells with or without Resistance to Selective MET Inhibition in another window
Includes: Supplementary data
Journal Articles

Analysis of Genetic Variants in Never-Smokers with Lung Cancer Facilitated by an Internet-Based Blood Collection Protocol: A Preliminary Report

Free
Nicolas Girard, Emil Lou, Christopher G. Azzoli, Rekha Reddy, Mark Robson, Megan Harlan, Irene Orlow, Yasushi Yatabe, Khedoudja Nafa, Marc Ladanyi, Agnes Viale, Mark G. Kris, Gregory Riely, Vincent Miller, Robert J. Klein, Keitaro Matsuo, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 755–763.
https://doi.org/10.1158/1078-0432.CCR-09-2437
Published: 14 January 2010
View articletitled, Analysis of Genetic Variants in Never-Smokers with Lung Cancer Facilitated by an Internet-Based Blood Collection Protocol: A Preliminary Report
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Includes: Supplementary data
Journal Articles

Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas

Free
Nicolas Girard, Ronglai Shen, Tianhua Guo, Maureen F. Zakowski, Adriana Heguy, Gregory J. Riely, James Huang, Christopher Lau, Alex E. Lash, Marc Ladanyi, Agnes Viale, Cristina R. Antonescu, William D. Travis, Valerie W. Rusch, Mark G. Kris, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6790–6799.
https://doi.org/10.1158/1078-0432.CCR-09-0644
Published: 11 November 2009
View articletitled, Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas
Open the PDF for Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas in another window
Includes: Supplementary data
Journal Articles

Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays

Free
Kevin K. Dobbin, David G. Beer, Matthew Meyerson, Timothy J. Yeatman, William L. Gerald, James W. Jacobson, Barbara Conley, Kenneth H. Buetow, Mervi Heiskanen, Richard M. Simon, John D. Minna, Luc Girard, David E. Misek, Jeremy M.G. Taylor, Samir Hanash, Katsuhiko Naoki, D. Neil Hayes, Christine Ladd-Acosta, Steven A. Enkemann, Agnes Viale, Thomas J. Giordano
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (2): 565–572.
https://doi.org/10.1158/1078-0432.565.11.2
Published: 08 February 2005
View articletitled, Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays
Open the PDF for Interlaboratory Comparability Study of Cancer Gene Expression Analysis Using Oligonucleotide Microarrays in another window
Includes: Supplementary data
Journal Articles

Casein Kinase II Alpha Subunit and C1-Inhibitor Are Independent Predictors of Outcome in Patients with Squamous Cell Carcinoma of the Lung

Free
Pornchai O-charoenrat, Valerie Rusch, Simon G. Talbot, Inderpal Sarkaria, Agnes Viale, Nicholas Socci, Ivan Ngai, Pulivarthi Rao, Bhuvanesh Singh
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5792–5803.
https://doi.org/10.1158/1078-0432.CCR-03-0317
Published: 08 September 2004
View articletitled, Casein Kinase II Alpha Subunit and C1-Inhibitor Are Independent Predictors of Outcome in Patients with Squamous Cell Carcinoma of the Lung
Open the PDF for Casein Kinase II Alpha Subunit and C1-Inhibitor Are Independent Predictors of Outcome in Patients with Squamous Cell Carcinoma of the Lung in another window
Journal Articles

Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site

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Cristina R. Antonescu, Agnes Viale, Lisa Sarran, Sylvia J. Tschernyavsky, Mithat Gonen, Neil H. Segal, Robert G. Maki, Nicholas D. Socci, Ronald P. DeMatteo, Peter Besmer
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (10): 3282–3290.
https://doi.org/10.1158/1078-0432.CCR-03-0715
Published: 24 May 2004
View articletitled, Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site
Open the PDF for Gene Expression in Gastrointestinal Stromal Tumors Is Distinguished by KIT Genotype and Anatomic Site in another window