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Adi F. Gazdar
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Journal Articles

Abstract B09: Evaluating transcription factor networks as targets for the treatment of small cell lung cancer

Karine Pozo, Rahul K. Kollipara, John D. Minna, Adi F. Gazdar, Jane E. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17_Supplement): B09.
https://doi.org/10.1158/1557-3265.AACRIASLC18-B09
Published: 01 September 2018
View article titled, Abstract B09: Evaluating transcription factor networks as targets for the treatment of small cell lung cancer
Journal Articles

Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC

Gurkan Mollaoglu, Matthew R. Guthrie, Stefanie Bohm, Johannes Bragelmann, Milind D. Chalishazar, Abbie S. Ireland, Fang Huang, Zeping Hu, Robert J. Cardnell, Triparna Sen, Jason Gertz, Jane E. Johnson, Adi F. Gazdar, Lauren A. Byers, Ralph J. DeBerardinis, Robert J. Wechsler-Reya, Martin Sos, Trudy G. Oliver
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17_Supplement): IA27.
https://doi.org/10.1158/1557-3265.AACRIASLC18-IA27
Published: 01 September 2018
View article titled, Abstract IA27: MYC drives molecular and therapeutically distinct subtype of SCLC
Journal Articles

An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer

Luc Girard, Jaime Rodriguez-Canales, Carmen Behrens, Debrah M. Thompson, Ihab W. Botros, Hao Tang, Yang Xie, Natasha Rekhtman, William D. Travis, Ignacio I. Wistuba, John D. Minna, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4880–4889.
https://doi.org/10.1158/1078-0432.CCR-15-2900
Published: 02 October 2016
View article titled, An Expression Signature as an Aid to the Histologic Classification of Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer

Oliver Delgado, Kimberly G. Batten, James A. Richardson, Xian-Jin Xie, Adi F. Gazdar, Aadil A. Kaisani, Luc Girard, Carmen Behrens, Milind Suraokar, Gail Fasciani, Woodring E. Wright, Michael D. Story, Ignacio I. Wistuba, John D. Minna, Jerry W. Shay
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (6): 1610–1622.
https://doi.org/10.1158/1078-0432.CCR-13-2589
Published: 13 March 2014
View article titled, Radiation-Enhanced Lung Cancer Progression in a Transgenic Mouse Model of Lung Cancer Is Predictive of Outcomes in Human Lung and Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract B24: A systematic search for cancer/testis antigens in lung cancer identifies VCX/Y genes expanding the repertoire of potential immunotherapeutic targets.

Ayumu Taguchi, Allen D. Taylor, Jaime Rodriguez, Muge Celiktas, Hui Liu, Xiaotu Ma, Qing Zhang, Chee-Hong Wong, Alice Chin, Luc Girard, Carmen Behrens, Wan Lam, Stephen Lam, John D. Minna, Ignacio I. Wistuba, Adi F. Gazdar, Samir M. Hanash
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2_Supplement): B24.
https://doi.org/10.1158/1078-0432.14AACRIASLC-B24
Published: 16 January 2014
View article titled, Abstract B24: A systematic search for cancer/testis antigens in lung cancer identifies VCX/Y genes expanding the repertoire of potential immunotherapeutic targets.
Journal Articles

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

Ximing Tang, Humam Kadara, Carmen Behrens, Diane D Liu, Yun Xiao, David Rice, Adi F. Gazdar, Junya Fujimoto, Cesar Moran, Marileila Varella-Garcia, J Jack Lee, Waun Ki Hong, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (8): 2434–2443.
https://doi.org/10.1158/1078-0432.CCR-10-1412
Published: 14 April 2011
View article titled, Abnormalities of the <em>TITF-1</em> Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis
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Includes: Supplementary data
Journal Articles

Color Fluorescence Ratio for Detection of Bronchial Dysplasia and Carcinoma In situ

Pyng Lee, Remco M. van den Berg, Stephen Lam, Adi F. Gazdar, Katrien Grunberg, Annette McWilliams, Jean LeRiche, Pieter E. Postmus, Tom G. Sutedja
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4700–4705.
https://doi.org/10.1158/1078-0432.CCR-08-1644
Published: 15 July 2009
View article titled, Color Fluorescence Ratio for Detection of Bronchial Dysplasia and Carcinoma <em>In situ</em>
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Includes: Supplementary data
Journal Articles

Synchronous Alterations of Wnt and Epidermal Growth Factor Receptor Signaling Pathways through Aberrant Methylation and Mutation in Non–Small Cell Lung Cancer

Makoto Suzuki, Hisayuki Shigematsu, Takahiro Nakajima, Rieko Kubo, Shinichiro Motohashi, Yasuo Sekine, Kiyoshi Shibuya, Toshihiko Iizasa, Kenzo Hiroshima, Yukio Nakatani, Adi F. Gazdar, Takehiko Fujisawa
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (20): 6087–6092.
https://doi.org/10.1158/1078-0432.CCR-07-0591
Published: 18 October 2007
View article titled, Synchronous Alterations of Wnt and Epidermal Growth Factor Receptor Signaling Pathways through Aberrant Methylation and Mutation in Non–Small Cell Lung Cancer
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Journal Articles

The Impact of Sex and Smoking Status on the Mutational Spectrum of Epidermal Growth Factor Receptor Gene in Non–small Cell Lung Cancer

Shinichi Toyooka, Keitaro Matsuo, Hisayuki Shigematsu, Takayuki Kosaka, Masaki Tokumo, Yasushi Yatabe, Syuji Ichihara, Michio Inukai, Hiroshi Suehisa, Junichi Soh, Katsuyuki Kiura, Kwun M. Fong, Huei Lee, Ignacio I. Wistuba, Adi F. Gazdar, Tetsuya Mitsudomi, Hiroshi Date
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5763–5768.
https://doi.org/10.1158/1078-0432.CCR-07-0216
Published: 01 October 2007
View article titled, The Impact of Sex and Smoking Status on the Mutational Spectrum of Epidermal Growth Factor Receptor Gene in Non–small Cell Lung Cancer
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Journal Articles

Distinct Epidermal Growth Factor Receptor and KRAS Mutation Patterns in Non–Small Cell Lung Cancer Patients with Different Tobacco Exposure and Clinicopathologic Features

Issan Yee San Tam, Lap Ping Chung, Wai Sing Suen, Elaine Wang, May C.M. Wong, Kok Keung Ho, Wah Kit Lam, Shui Wah Chiu, Luc Girard, John D. Minna, Adi F. Gazdar, Maria P. Wong
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (5): 1647–1653.
https://doi.org/10.1158/1078-0432.CCR-05-1981
Published: 06 March 2006
View article titled, Distinct Epidermal Growth Factor Receptor and <em>KRAS</em> Mutation Patterns in Non–Small Cell Lung Cancer Patients with Different Tobacco Exposure and Clinicopathologic Features
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Journal Articles

Promoter Hypermethylation Profile of Ovarian Epithelial Neoplasms

Prakash B. Makarla, M. Hossein Saboorian, Raheela Ashfaq, Kiyomi O. Toyooka, Shinichi Toyooka, John D. Minna, Adi F. Gazdar, John O. Schorge
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (15): 5365–5369.
https://doi.org/10.1158/1078-0432.CCR-04-2455
Published: 01 August 2005
View article titled, Promoter Hypermethylation Profile of Ovarian Epithelial Neoplasms
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Journal Articles

The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers

Masaki Tokumo, Shinichi Toyooka, Katsuyuki Kiura, Hisayuki Shigematsu, Kunitoshi Tomii, Motoi Aoe, Kouichi Ichimura, Toshihide Tsuda, Masaaki Yano, Kazunori Tsukuda, Masahiro Tabata, Hiroshi Ueoka, Mitsune Tanimoto, Hiroshi Date, Adi F. Gazdar, Nobuyoshi Shimizu
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (3): 1167–1173.
https://doi.org/10.1158/1078-0432.1167.11.3
Published: 11 February 2005
View article titled, The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers
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Journal Articles

Aberrant Promoter Hypermethylation of Multiple Genes in Gallbladder Carcinoma and Chronic Cholecystitis

Takao Takahashi, Narayan Shivapurkar, Erick Riquelme, Hisayuki Shigematsu, Jyotsna Reddy, Makoto Suzuki, Kuniharu Miyajima, Xian Zhou, B. Nebiyou Bekele, Adi F. Gazdar, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 6126–6133.
https://doi.org/10.1158/1078-0432.CCR-04-0579
Published: 24 September 2004
View article titled, Aberrant Promoter Hypermethylation of Multiple Genes in Gallbladder Carcinoma and Chronic Cholecystitis
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Journal Articles

DNA Methylation Profiles of Lymphoid and Hematopoietic Malignancies

Takao Takahashi, Narayan Shivapurkar, Jyotsna Reddy, Hisayuki Shigematsu, Kuniharu Miyajima, Makoto Suzuki, Shinichi Toyooka, Sabine Zöchbauer-Müller, Johannes Drach, Gunjan Parikh, Yingye Zheng, Ziding Feng, Steven H. Kroft, Charles Timmons, Robert W. McKenna, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (9): 2928–2935.
https://doi.org/10.1158/1078-0432.CCR-03-0716
Published: 06 May 2004
View article titled, DNA Methylation Profiles of Lymphoid and Hematopoietic Malignancies
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Journal Articles

Aberrant Promoter Methylation in Human DAB2 Interactive Protein ( hDAB2IP ) Gene in Breast Cancer

Hideaki Dote, Shinichi Toyooka, Kazunori Tsukuda, Masaaki Yano, Mamoru Ouchida, Hiroyoshi Doihara, Makoto Suzuki, Hong Chen, Jer-Tsong Hsieh, Adi F. Gazdar, Nobuyoshi Shimizu
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (6): 2082–2089.
https://doi.org/10.1158/1078-0432.CCR-03-0236
Published: 24 March 2004
View article titled, Aberrant Promoter Methylation in Human DAB2 Interactive Protein ( <em>hDAB2IP</em> ) Gene in Breast Cancer
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Journal Articles

Aberrant Promoter Methylation and Silencing of Laminin-5-Encoding Genes in Breast Carcinoma

Ubaradka G. Sathyanarayana, Asha Padar, Chun Xian Huang, Makoto Suzuki, Hisayuki Shigematsu, B. Nebiyou Bekele, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6389–6394.
Published: 24 December 2003
View article titled, Aberrant Promoter Methylation and Silencing of Laminin-5-Encoding Genes in Breast Carcinoma
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Journal Articles

Aberrant Promoter Methylation of Laminin-5–Encoding Genes in Prostate Cancers and Its Relationship to Clinicopathological Features

Ubaradka G. Sathyanarayana, Asha Padar, Makoto Suzuki, Riichiroh Maruyama, Hisayuki Shigematsu, Jer-Tsong Hsieh, Eugene P. Frenkel, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6395–6400.
Published: 24 December 2003
View article titled, Aberrant Promoter Methylation of Laminin-5–Encoding Genes in Prostate Cancers and Its Relationship to Clinicopathological Features
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Journal Articles

Alterations in the Mitochondrial Displacement Loop in Lung Cancers

Makoto Suzuki, Shinichi Toyooka, Kuniharu Miyajima, Toshihiko Iizasa, Takehiko Fujisawa, Nebiyou B. Bekele, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (15): 5636–5641.
Published: 03 December 2003
View article titled, Alterations in the Mitochondrial Displacement Loop in Lung Cancers
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Journal Articles

Inactivation of Cyclin D2 Gene in Prostate Cancers by Aberrant Promoter Methylation

Asha Padar, Ubaradka G. Sathyanarayana, Makoto Suzuki, Riichiroh Maruyama, Jer-Tsong Hsieh, Eugene P. Frenkel, John D. Minna, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (13): 4730–4734.
Published: 27 October 2003
View article titled, Inactivation of <em>Cyclin D2</em> Gene in Prostate Cancers by Aberrant Promoter Methylation
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Journal Articles

Distinct K- ras Mutation Pattern Characterizes Signet Ring Cell Colorectal Carcinoma

Ignacio I. Wistuba, Carmen Behrens, Jorge Albores-Saavedra, Ruby Delgado, Francisco Lopez, Adi F. Gazdar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3615–3619.
Published: 23 September 2003
View article titled, Distinct K- <em>ras</em> Mutation Pattern Characterizes Signet Ring Cell Colorectal Carcinoma
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