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Adel K. El-Naggar
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Journal Articles

Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets

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Renata Ferrarotto, Yoshitsugu Mitani, Daniel J. McGrail, Kaiyi Li, Tatiana V. Karpinets, Diana Bell, Steven J. Frank, Xingzhi Song, Michael E. Kupferman, Bin Liu, J. Jack Lee, Bonnie S. Glisson, Jianhua Zhang, Jon C. Aster, Shiaw-Yih Lin, P. Andrew Futreal, John V. Heymach, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (14): 2737.
https://doi.org/10.1158/1078-0432.CCR-23-1697
Published: 14 July 2023
View articletitled, Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
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Journal Articles

Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets

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Renata Ferrarotto, Yoshitsugu Mitani, Daniel J. McGrail, Kaiyi Li, Tatiana V. Karpinets, Diana Bell, Steven J. Frank, Xingzhi Song, Michael E. Kupferman, Bin Liu, J. Jack Lee, Bonnie S. Glisson, Jianhua Zhang, Jon C. Aster, Shiaw-Yih Lin, P. Andrew Futreal, John V. Heymach, Adel K. El-Naggar
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (3): 852–864.
https://doi.org/10.1158/1078-0432.CCR-20-1192
Published: 01 February 2023
View articletitled, Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
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Includes: Supplementary data
Journal Articles

Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

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Renata Ferrarotto, Moran Amit, Priyadharsini Nagarajan, M. Laura Rubin, Ying Yuan, Diana Bell, Adel K. El-Naggar, Jason M. Johnson, William H. Morrison, David I. Rosenthal, Bonnie S. Glisson, Faye M. Johnson, Charles Lu, Frank E. Mott, Bita Esmaeli, Eduardo M. Diaz, Jr, Paul W. Gidley, Ryan P. Goepfert, Carol M. Lewis, Randal S. Weber, Jennifer A. Wargo, Sreyashi Basu, Fei Duan, Shalini S. Yadav, Padmanee Sharma, James P. Allison, Jeffrey N. Myers, Neil D. Gross
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (8): 1735.
https://doi.org/10.1158/1078-0432.CCR-22-0468
Published: 14 April 2022
View articletitled, Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck
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Includes: Supplementary data
Journal Articles

Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

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Renata Ferrarotto, Moran Amit, Priyadharsini Nagarajan, M. Laura Rubin, Ying Yuan, Diana Bell, Adel K. El-Naggar, Jason M. Johnson, William H. Morrison, David I. Rosenthal, Bonnie S. Glisson, Faye M. Johnson, Charles Lu, Frank E. Mott, Bita Esmaeli, Eduardo M. Diaz, Jr, Paul W. Gidley, Ryan P. Goepfert, Carol M. Lewis, Randal S. Weber, Jennifer A. Wargo, Sreyashi Basu, Fei Duan, Shalini S. Yadav, Padmanee Sharma, James P. Allison, Jeffrey N. Myers, Neil D. Gross
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4557–4565.
https://doi.org/10.1158/1078-0432.CCR-21-0585
Published: 15 August 2021
View articletitled, Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck
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Includes: Supplementary data
Journal Articles

Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations

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Tatiana V. Karpinets, Yoshitsugu Mitani, Bin Liu, Jianhua Zhang, Kristen B. Pytynia, Linton D. Sellen, Danice T. Karagiannis, Renata Ferrarotto, Andrew P. Futreal, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 3960–3969.
https://doi.org/10.1158/1078-0432.CCR-20-4071
Published: 15 July 2021
View articletitled, Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations
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Includes: Supplementary data
Journal Articles

Reciprocal and Autonomous Glucocorticoid and Androgen Receptor Activation in Salivary Duct Carcinoma

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Yoshitsugu Mitani, Sue-Hwa Lin, Kristen B. Pytynia, Renata Ferrarotto, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (5): 1175–1184.
https://doi.org/10.1158/1078-0432.CCR-19-1603
Published: 02 March 2020
View articletitled, Reciprocal and Autonomous Glucocorticoid and Androgen Receptor Activation in Salivary Duct Carcinoma
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Includes: Supplementary data
Journal Articles

Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

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Seung-Hyun Oh, Woo-Young Kim, Jai-Hyun Kim, Maher N. Younes, Adel K. El-Naggar, Jeffrey N. Myers, Merril Kies, Pinchas Cohen, Fadlo Khuri, Waun K. Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4861.
https://doi.org/10.1158/1078-0432.CCR-19-2054
Published: 01 August 2019
View articletitled, Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma
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Journal Articles

Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer

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Bradley A. Schiff, Andrea B. McMurphy, Samar A. Jasser, Maher N. Younes, Dao Doan, Orhan G. Yigitbasi, Seungwon Kim, Ge Zhou, Mahitosh Mandal, Benjamin N. Bekele, F. Christopher Holsinger, Steven I. Sherman, Sai-Ching Yeung, Adel K. El-Naggar, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4862.
https://doi.org/10.1158/1078-0432.CCR-19-2052
Published: 01 August 2019
View articletitled, Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer
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Journal Articles

Novel MYBL1 Gene Rearrangements with Recurrent MYBL1–NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations

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Yoshitsugu Mitani, Bin Liu, Pulivarthi H. Rao, Vishnupriya J. Borra, Mark Zafereo, Randal S. Weber, Merrill Kies, Guillermina Lozano, P. Andrew Futreal, Carlos Caulin, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 725–733.
https://doi.org/10.1158/1078-0432.CCR-15-2867-T
Published: 31 January 2016
View articletitled, Novel MYBL1 Gene Rearrangements with Recurrent MYBL1–NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations
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Includes: Supplementary data
Journal Articles

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

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Curtis R. Pickering, Jane H. Zhou, J. Jack Lee, Jennifer A. Drummond, S. Andrew Peng, Rami E. Saade, Kenneth Y. Tsai, Jonathan L. Curry, Michael T. Tetzlaff, Stephen Y. Lai, Jun Yu, Donna M. Muzny, Harshavardhan Doddapaneni, Eve Shinbrot, Kyle R. Covington, Jianhua Zhang, Sahil Seth, Carlos Caulin, Gary L. Clayman, Adel K. El-Naggar, Richard A. Gibbs, Randal S. Weber, Jeffrey N. Myers, David A. Wheeler, Mitchell J. Frederick
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6582–6592.
https://doi.org/10.1158/1078-0432.CCR-14-1768
Published: 14 December 2014
View articletitled, Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Alterations Associated with Androgen Receptor Gene Activation in Salivary Duct Carcinoma of Both Sexes: Potential Therapeutic Ramifications

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Yoshitsugu Mitani, Pulivarthi H. Rao, Sankar N. Maity, Yu-Chen Lee, Renata Ferrarotto, Julian C. Post, Lisa Licitra, Scott M. Lippman, Merrill S. Kies, Randal S. Weber, Carlos Caulin, Sue-Hwa Lin, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6570–6581.
https://doi.org/10.1158/1078-0432.CCR-14-1746
Published: 14 December 2014
View articletitled, Alterations Associated with Androgen Receptor Gene Activation in Salivary Duct Carcinoma of Both Sexes: Potential Therapeutic Ramifications
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Includes: Supplementary data
Journal Articles

Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers

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Curtis R. Pickering, Jiexin Zhang, David M. Neskey, Mei Zhao, Samar A. Jasser, Jiping Wang, Alexandra Ward, C. Jillian Tsai, Marcus V. Ortega Alves, Jane H. Zhou, Jennifer Drummond, Adel K. El-Naggar, Richard Gibbs, John N. Weinstein, David A. Wheeler, Jing Wang, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3842–3848.
https://doi.org/10.1158/1078-0432.CCR-14-0565
Published: 14 July 2014
View articletitled, Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers
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Includes: Supplementary data
Journal Articles

A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck

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Carol M. Lewis, Bonnie S. Glisson, Lei Feng, Fiona Wan, Ximing Tang, Ignacio I. Wistuba, Adel K. El-Naggar, David I. Rosenthal, Mark S. Chambers, Robert A. Lustig, Randal S. Weber
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (5): 1435–1446.
https://doi.org/10.1158/1078-0432.CCR-11-1951
Published: 01 March 2012
View articletitled, A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck
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Includes: Supplementary data
Journal Articles

STAT5A-Mediated SOCS2 Expression Regulates Jak2 and STAT3 Activity Following c-Src Inhibition in Head and Neck Squamous Carcinoma

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Banibrata Sen, Shaohua Peng, Denise M. Woods, Ignacio Wistuba, Diana Bell, Adel K. El-Naggar, Stephen Y. Lai, Faye M. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (1): 127–139.
https://doi.org/10.1158/1078-0432.CCR-11-1889
Published: 02 January 2012
View articletitled, STAT5A-Mediated SOCS2 Expression Regulates Jak2 and STAT3 Activity Following c-Src Inhibition in Head and Neck Squamous Carcinoma
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Includes: Supplementary data
Journal Articles

Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with MYB–NFIB Chimeric Fusion, MYB Expression, and Clinical Outcome

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Yoshitsugu Mitani, Pulivarthi H. Rao, P. Andrew Futreal, Dianna B. Roberts, Philip J. Stephens, Yi-Jue Zhao, Li Zhang, Mutsumi Mitani, Randal S. Weber, Scott M. Lippman, Carlos Caulin, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (22): 7003–7014.
https://doi.org/10.1158/1078-0432.CCR-11-1870
Published: 14 November 2011
View articletitled, Novel Chromosomal Rearrangements and Break Points at the t(6;9) in Salivary Adenoid Cystic Carcinoma: Association with MYB–NFIB Chimeric Fusion, MYB Expression, and Clinical Outcome
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Includes: Supplementary data
Journal Articles

IQGAP1 Plays an Important Role in the Invasiveness of Thyroid Cancer

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Zhi Liu, Dingxie Liu, Ermal Bojdani, Adel K. El-Naggar, Vasily Vasko, Mingzhao Xing
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (24): 6009–6018.
https://doi.org/10.1158/1078-0432.CCR-10-1627
Published: 16 December 2010
View articletitled, IQGAP1 Plays an Important Role in the Invasiveness of Thyroid Cancer
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Includes: Supplementary data
Journal Articles

Comprehensive Analysis of the MYB-NFIB Gene Fusion in Salivary Adenoid Cystic Carcinoma: Incidence, Variability, and Clinicopathologic Significance

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Yoshitsugu Mitani, Jie Li, Pulivarthi H. Rao, Yi-Jue Zhao, Diana Bell, Scott M. Lippman, Randal S. Weber, Carlos Caulin, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19): 4722–4731.
https://doi.org/10.1158/1078-0432.CCR-10-0463
Published: 29 September 2010
View articletitled, Comprehensive Analysis of the MYB-NFIB Gene Fusion in Salivary Adenoid Cystic Carcinoma: Incidence, Variability, and Clinicopathologic Significance
Open the PDF for Comprehensive Analysis of the MYB-NFIB Gene Fusion in Salivary Adenoid Cystic Carcinoma: Incidence, Variability, and Clinicopathologic Significance in another window
Includes: Supplementary data
Journal Articles

Genetic and Expression Analysis of HER-2 and EGFR Genes in Salivary Duct Carcinoma: Empirical and Therapeutic Significance

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Michelle D. Williams, Dianna B. Roberts, Merrill S. Kies, Li Mao, Randal S. Weber, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2266–2274.
https://doi.org/10.1158/1078-0432.CCR-09-0238
Published: 14 April 2010
View articletitled, Genetic and Expression Analysis of HER-2 and EGFR Genes in Salivary Duct Carcinoma: Empirical and Therapeutic Significance
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Includes: Supplementary data
Journal Articles

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

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Li-E Wang, Zhibin Hu, Erich M. Sturgis, Margaret R. Spitz, Sara S. Strom, Christopher I. Amos, Zhaozheng Guo, Yawei Qiao, Ann Marie Gillenwater, Jeffrey N. Myers, Gary L. Clayman, Randal S. Weber, Adel K. El-Naggar, Li Mao, Scott M. Lippman, Waun Ki Hong, Qingyi Wei
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 764–774.
https://doi.org/10.1158/1078-0432.CCR-09-2156
Published: 14 January 2010
View articletitled, Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics
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Journal Articles

Phase I Trial of a Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Advanced Malignancies

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David S. Hong, Said M. Sebti, Robert A. Newman, Michelle A. Blaskovich, Lei Ye, Robert F. Gagel, Stacy Moulder, Jennifer J. Wheler, Aung Naing, Nizar M. Tannir, Chaan S. Ng, Steven I. Sherman, Adel K. El Naggar, Rabia Khan, Jon Trent, John J. Wright, Razelle Kurzrock
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 7061–7068.
https://doi.org/10.1158/1078-0432.CCR-09-1241
Published: 11 November 2009
View articletitled, Phase I Trial of a Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Advanced Malignancies
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