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A. Craig Lockhart
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Journal Articles

Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma

Philip A. Philip, Ibrahim Azar, Joanne Xiu, Michael J. Hall, Andrew Eugene Hendifar, Emil Lou, Jimmy J. Hwang, Jun Gong, Rebecca Feldman, Michelle Ellis, Phil Stafford, David Spetzler, Moh'd M. Khushman, Davendra Sohal, A. Craig Lockhart, Benjamin A. Weinberg, Wafik S. El-Deiry, John Marshall, Anthony F. Shields, W. Michael Korn
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2704–2714.
https://doi.org/10.1158/1078-0432.CCR-21-3581
Published: 13 June 2022
View article titled, Molecular Characterization of <em>KRAS</em> Wild-type Tumors in Patients with Pancreatic Adenocarcinoma
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Includes: Supplementary data
Journal Articles

A Combination of SAHA and Quinacrine Is Effective in Inducing Cancer Cell Death in Upper Gastrointestinal Cancers

Shoumin Zhu, Zheng Chen, Lihong Wang, Dunfa Peng, Abbes Belkhiri, A. Craig Lockhart, Wael El-Rifai
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (8): 1905–1916.
https://doi.org/10.1158/1078-0432.CCR-17-1716
Published: 12 April 2018
View article titled, A Combination of SAHA and Quinacrine Is Effective in Inducing Cancer Cell Death in Upper Gastrointestinal Cancers
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Includes: Supplementary data
Journal Articles

A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer

Cynthia X. Ma, Cesar Sanchez, Feng Gao, Robert Crowder, Michael Naughton, Timothy Pluard, Allison Creekmore, Zhanfang Guo, Jeremy Hoog, A. Craig Lockhart, Austin Doyle, Charles Erlichman, Matthew J. Ellis
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (11): 2650–2658.
https://doi.org/10.1158/1078-0432.CCR-15-2160
Published: 31 May 2016
View article titled, A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer
Open the PDF for A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

Venkataswarup Tiriveedhi, Natalia Tucker, John Herndon, Lijin Li, Mark Sturmoski, Matthew Ellis, Cynthia Ma, Michael Naughton, A. Craig Lockhart, Feng Gao, Timothy Fleming, Peter Goedegebuure, Thalachallour Mohanakumar, William E. Gillanders
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 5964–5975.
https://doi.org/10.1158/1078-0432.CCR-14-0059
Published: 30 November 2014
View article titled, Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer
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Includes: Supplementary data
Journal Articles

The Pharmacokinetics and Safety of ABT-751, a Novel, Orally Bioavailable Sulfonamide Antimitotic Agent: Results of a Phase 1 Study

Kenneth R. Hande, Anne Hagey, Jordan Berlin, Yingna Cai, Kysa Meek, Hiro Kobayashi, A. Craig Lockhart, Diane Medina, Jeffrey Sosman, Gary B. Gordon, Mace L. Rothenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (9): 2834–2840.
https://doi.org/10.1158/1078-0432.CCR-05-2159
Published: 04 May 2006
View article titled, The Pharmacokinetics and Safety of ABT-751, a Novel, Orally Bioavailable Sulfonamide Antimitotic Agent: Results of a Phase 1 Study
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Journal Articles

A Phase I Dose-Escalation and Pharmacokinetic Study of Brostallicin (PNU-166196A), a Novel DNA Minor Groove Binder, in Adult Patients with Advanced Solid Tumors

A. Craig Lockhart, Martin Howard, Kenneth R. Hande, Bruce J. Roth, Jordan D. Berlin, Franzanne Vreeland, Angela Campbell, Erminia Fontana, Francesca Fiorentini, Camilla Fowst, Victoria A. Paty, Odessa Lankford, Mace L. Rothenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (2): 468–475.
https://doi.org/10.1158/1078-0432.CCR-0658-03
Published: 03 February 2004
View article titled, A Phase I Dose-Escalation and Pharmacokinetic Study of Brostallicin (PNU-166196A), a Novel DNA Minor Groove Binder, in Adult Patients with Advanced Solid Tumors
Open the PDF for A Phase I Dose-Escalation and Pharmacokinetic Study of Brostallicin (PNU-166196A), a Novel DNA Minor Groove Binder, in Adult Patients with Advanced Solid Tumors in another window
Journal Articles

Reduction of Wound Angiogenesis in Patients Treated with BMS-275291, a Broad Spectrum Matrix Metalloproteinase Inhibitor

A. Craig Lockhart, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Jeffrey S. Humphrey, Seth Thompson, Kathleen M. Williams, Bruce Klitzman, Fan Yuan, James M. Grichnik, Alan D. Proia, Delina A. Conway, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 586–593.
Published: 01 February 2003
View article titled, Reduction of Wound Angiogenesis in Patients Treated with BMS-275291, a Broad Spectrum Matrix Metalloproteinase Inhibitor
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Journal Articles

The Novel Tubulin-binding Drug BTO-956 Inhibits R3230Ac Mammary Carcinoma Growth and Angiogenesis in Fischer 344 Rats

Siqing Shan, A. Craig Lockhart, Wilfred Y. Saito, A. Merrill Knapp, Keith R. Laderoute, Mark W. Dewhirst
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (8): 2590–2596.
Published: 01 August 2001
View article titled, The Novel Tubulin-binding Drug BTO-956 Inhibits R3230Ac Mammary Carcinoma Growth and Angiogenesis in Fischer 344 Rats
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