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A. Ari Hakimi
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Journal Articles

Associations between Pretreatment Body Composition Features and Clinical Outcomes among Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Blockade

Yasser Ged, Alejandro Sanchez, Sujata Patil, Andrea Knezevic, Emily Stein, Stacey Petruzella, Kate Weiss, Cihan Duzgol, Joshua Chaim, Oguz Akin, Marina Mourtzakis, Michael T. Paris, Jessica Scott, Fengshen Kuo, Ritesh Kotecha, A. Ari Hakimi, Chung-Han Lee, Robert J. Motzer, Martin H. Voss, Helena Furberg
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5180–5189.
https://doi.org/10.1158/1078-0432.CCR-22-1389
Published: 01 December 2022
View article titled, Associations between Pretreatment Body Composition Features and Clinical Outcomes among Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Blockade
Open the PDF for Associations between Pretreatment Body Composition Features and Clinical Outcomes among Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

XL-ing at Induction of Apoptosis in Kidney Cancer through Inhibition of BCL-XL

Naitao Wang, A. Ari Hakimi, Yu Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (21): 4600–4602.
https://doi.org/10.1158/1078-0432.CCR-22-2104
Published: 01 November 2022
View article titled, XL-ing at Induction of Apoptosis in Kidney Cancer through Inhibition of BCL-X<sub>L</sub>
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Journal Articles

From Basic Science to Clinical Translation in Kidney Cancer: A Report from the Second Kidney Cancer Research Summit

Toni K. Choueiri, Laurence Albiges, Michael B. Atkins, Ziad Bakouny, Gennady Bratslavsky, David A. Braun, Naomi B. Haas, John B.A.G. Haanen, A. Ari Hakimi, Michael A.S. Jewett, Eric Jonasch, William G. Kaelin, Jr, Payal Kapur, Chris Labaki, Bryan Lewis, David F. McDermott, Sumanta K. Pal, Kevin Pels, Susan Poteat, Thomas Powles, W. Kimryn Rathmell, Brian I. Rini, Sabina Signoretti, Nizar M. Tannir, Robert G. Uzzo, Hans J. Hammers
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 831–839.
https://doi.org/10.1158/1078-0432.CCR-21-3238
Published: 03 March 2022
View article titled, From Basic Science to Clinical Translation in Kidney Cancer: A Report from the Second Kidney Cancer Research Summit
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Journal Articles

Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma

Kyrollis Attalla, Renzo G. DiNatale, Phillip M. Rappold, Christopher J. Fong, Francisco Sanchez-Vega, Andrew W. Silagy, Stanley Weng, Jonathan Coleman, Chung-Han Lee, Maria I. Carlo, Jeremy C. Durack, Stephen B. Solomon, Victor E. Reuter, Paul Russo, Timothy A. Chan, Robert J. Motzer, Nikolaus D. Schultz, Ed Reznik, Martin H. Voss, A. Ari Hakimi
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (20): 5595–5606.
https://doi.org/10.1158/1078-0432.CCR-20-4058
Published: 15 October 2021
View article titled, Prevalence and Landscape of Actionable Genomic Alterations in Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Comprehensive Molecular Characterization and Response to Therapy in Fumarate Hydratase–Deficient Renal Cell Carcinoma

Jack P. Gleeson, Ines Nikolovski, Renzo Dinatale, Mark Zucker, Andrea Knezevic, Sujata Patil, Yasser Ged, Ritesh R. Kotecha, Natalie Shapnik, Samuel Murray, Paul Russo, Jonathan Coleman, Chung Han Lee, Zsofia K. Stadler, A. Ari Hakimi, Darren R. Feldman, Robert J. Motzer, Ed Reznik, Martin H. Voss, Ying-Bei Chen, Maria I. Carlo
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2910–2919.
https://doi.org/10.1158/1078-0432.CCR-20-4367
Published: 15 May 2021
View article titled, Comprehensive Molecular Characterization and Response to Therapy in Fumarate Hydratase–Deficient Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Comprehensive Genomic Analysis of Translocation Renal Cell Carcinoma Reveals Copy-Number Variations as Drivers of Disease Progression

Julian Marcon, Renzo G. DiNatale, Alejandro Sanchez, Ritesh R. Kotecha, Sounak Gupta, Fengshen Kuo, Vladimir Makarov, Amar Sandhu, Roy Mano, Andrew W. Silagy, Kyle A. Blum, Daniel E. Nassau, Nicole E. Benfante, Michael V. Ortiz, Maria I. Carlo, Timothy A. Chan, Robert J. Motzer, Martin H. Voss, Jonathan Coleman, Paul Russo, Victor Reuter, A. Ari Hakimi, Ed Reznik
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3629–3640.
https://doi.org/10.1158/1078-0432.CCR-19-3283
Published: 15 July 2020
View article titled, Comprehensive Genomic Analysis of Translocation Renal Cell Carcinoma Reveals Copy-Number Variations as Drivers of Disease Progression
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Includes: Supplementary data
Journal Articles

The Immune Microenvironment and Neoantigen Landscape of Aggressive Salivary Gland Carcinomas Differ by Subtype

Maximilian Linxweiler, Fengshen Kuo, Nora Katabi, Mark Lee, Zaineb Nadeem, Martin G. Dalin, Vladimir Makarov, Diego Chowell, Snjezana Dogan, Ian Ganly, A. Ari Hakimi, Richard J. Wong, Nadeem Riaz, Alan L. Ho, Timothy A. Chan, Luc G.T. Morris
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (12): 2859–2870.
https://doi.org/10.1158/1078-0432.CCR-19-3758
Published: 15 June 2020
View article titled, The Immune Microenvironment and Neoantigen Landscape of Aggressive Salivary Gland Carcinomas Differ by Subtype
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Includes: Supplementary data
Journal Articles

PTEN Expression, Not Mutation Status in TSC1, TSC2, or mTOR, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial

Martin H. Voss, David Chen, Albert Reising, Mahtab Marker, Jiayuan Shi, Jianning Xu, Irina Ostrovnaya, Venkatraman E. Seshan, Almedina Redzematovic, Ying-Bei Chen, Parul Patel, Xia Han, James J. Hsieh, A. Ari Hakimi, Robert J. Motzer
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (2): 506–514.
https://doi.org/10.1158/1078-0432.CCR-18-1833
Published: 15 January 2019
View article titled, PTEN Expression, Not Mutation Status in <em>TSC1, TSC2</em>, or <em>mTOR</em>, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial
Open the PDF for PTEN Expression, Not Mutation Status in <em>TSC1, TSC2</em>, or <em>mTOR</em>, Correlates with the Outcome on Everolimus in Patients with Renal Cell Carcinoma Treated on the Randomized RECORD-3 Trial in another window
Includes: Supplementary data
Journal Articles

Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy

Martin H. Voss, A. Ari Hakimi, Can G. Pham, A. Rose Brannon, Ying-Bei Chen, Luis F. Cunha, Oguz Akin, Han Liu, Shugaku Takeda, Sasinya N. Scott, Nicholas D. Socci, Agnes Viale, Nikolaus Schultz, Chris Sander, Victor E. Reuter, Paul Russo, Emily H. Cheng, Robert J. Motzer, Michael F. Berger, James J. Hsieh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (7): 1955–1964.
https://doi.org/10.1158/1078-0432.CCR-13-2345
Published: 31 March 2014
View article titled, Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy
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Includes: Supplementary data
Journal Articles

Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network

A. Ari Hakimi, Irina Ostrovnaya, Boris Reva, Nikolaus Schultz, Ying-Bei Chen, Mithat Gonen, Han Liu, Shugaku Takeda, Martin H. Voss, Satish K. Tickoo, Victor E. Reuter, Paul Russo, Emily H. Cheng, Chris Sander, Robert J. Motzer, James J. Hsieh
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (12): 3259–3267.
https://doi.org/10.1158/1078-0432.CCR-12-3886
Published: 13 June 2013
View article titled, Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators <em>BAP1</em> and <em>SETD2</em>: A Report by MSKCC and the KIRC TCGA Research Network
Open the PDF for Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators <em>BAP1</em> and <em>SETD2</em>: A Report by MSKCC and the KIRC TCGA Research Network in another window
Includes: Supplementary data