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CCR Focus Archive 2017


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Clinical Trial Design Considerations in the Immuno-oncology Era (September 1, 2017)
Breast Cancer Research: From Base Pairs to Populations (June 1, 2017)
Pancreatic Cancer: Challenge and Inspiration (April 1, 2017)

2017 CCR Focus Sections


CCR Focus Cover, September 1, 2017 issue

Clinical Trial Design Considerations in the Immuno-oncology Era
September 1, 2017
Guest Editors: Lillian L. Siu, S. Percy Ivy, Gary L. Rosner, 23(17): 4947-5002

Refining Immunotherapy Approvals
Susan E. Bates

Challenges and Opportunities in Adapting Clinical Trial Design for Immunotherapies
Lillian L. Siu, S. Percy Ivy, Erica L. Dixon, Amy E. Gravell, Steven A. Reeves, and Gary L. Rosner

Immuno-oncology Trial Endpoints: Capturing Clinically Meaningful Activity
Valsamo Anagnostou, Mark Yarchoan, Aaron R. Hansen, Hao Wang, Franco Verde, Elad Sharon, Deborah Collyar, Laura Q.M. Chow, and Patrick M. Forde

The Challenge for Development of Valuable Immuno-oncology Biomarkers
Janice M. Mehnert, Arta M. Monjazeb, Johanna M.T. Beerthuijzen, Deborah Collyar, Larry Rubinstein, and Lyndsay N. Harris

From Famine to Feast: Developing Early-Phase Combination Immunotherapy Trials Wisely
Daphne Day, Arta M. Monjazeb, Elad Sharon, S. Percy Ivy, Eric H. Rubin, Gary L. Rosner, and Marcus O. Butler

Immuno-oncology Clinical Trial Design: Limitations, Challenges, and Opportunities
Christina S. Baik, Eric H. Rubin, Patrick M. Forde, Janice M. Mehnert, Deborah Collyar, Marcus O. Butler, Erica L. Dixon, and Laura Q.M. Chow



CCR Focus Cover, April 1, 2017 issue

Pancreatic Cancer: Challenge and Inspiration
April 1, 2017
Guest Editors: Daniel D. Von Hoff, John A. Chabot, Susan E. Bates, 22(7): 1628-1678

Pancreatic Cancer: Challenge and Inspiration
Susan E. Bates

Pancreatic Cancer: “A Riddle Wrapped in a Mystery inside an Enigma”
Erkut Borazanci, Chi V. Dang, Robert W. Robey, Susan E. Bates, John A. Chabot and Daniel D. Von Hoff

Pancreatic Cancer Genomes: Implications for Clinical Management and Therapeutic Development
Stephan B. Dreyer, David K. Chang, Peter Bailey and Andrew V. Biankin

Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked
Gerard I. Evan, Nasun Hah, Trevor D. Littlewood, Nicole M. Sodir, Tania Campos, Michael Downes and Ronald M. Evans

Strategies for Increasing Pancreatic Tumor Immunogenicity
Burles A. Johnson III, Mark Yarchoan, Valerie Lee, Daniel A. Laheru and Elizabeth M. Jaffee

Current and Emerging Therapies in Metastatic Pancreatic Cancer
Gulam Abbas Manji, Kenneth P. Olive, Yvonne M. Saenger and Paul Oberstein

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