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CCR Focus Archive 2007

CCR Focus Archive Home

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Cell Death (December 15, 2007)
Immune Regulation and Immunotherapy (September 15, 2007)
Imaging Update: New Windows, New Views (June 15, 2007)
CNS Metastasis: An Old Problem in a New Guise (March 15, 2007)

2007 CCR Focus Sections

CCR Focus Cover

Cell Death
December 15, 2007
Guest Editor: Edward Benz and David Nathan, 13 (24) : 7225–7522

From the Editor
Susan E. Bates

Edward J. Benz, Jr. and David G. Nathan

Targeting the Cell Death-Survival Equation
Edward J. Benz, Jr., David G. Nathan, Ravi K. Amaravadi, and Nika N. Danial

BCL-2 Family Proteins: Critical Checkpoints of Apoptotic Cell Death
Nika N. Danial

The Challenge of Drugging Undruggable Targets in Cancer: Lessons Learned from Targeting BCL-2 Family Members
Gregory L. Verdine and Loren D. Walensky

The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment
Ravi K. Amaravadi and Craig B. Thompson

Is Cell Death a Critical End Point for Anticancer Therapies or Is Cytostasis Sufficient?
Olivier Rixe and Tito Fojo

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CCR Focus Cover

Immune Regulation and Immunotherapy
September 15, 2007
Guest Editor: Patrick Hwu, 13 (18) : 5227–5660s

From the Editor
Susan E. Bates

Less Yin, More Yang: Confronting the Barriers to Cancer Immunotherapy
Gregory Lizée, Mayra A. Cantu, and Patrick Hwu

Failure at the Effector Phase: Immune Barriers at the Level of the Melanoma Tumor Microenvironment
Thomas F. Gajewski

Transforming Growth Factor-ß and the Immune Response: Implications for Anticancer Therapy
Stephen H. Wrzesinski, Yisong Y. Wan, and Richard A. Flavell

The B7 Family and Cancer Therapy: Costimulation and Coinhibition
Xingxing Zang and James P. Allison

Toll-like Receptors in Tumor Immunotherapy
Chrystal M. Paulos, Andrew Kaiser, Claudia Wrzesinski, Christian S. Hinrichs, Lydie Cassard, Andrea Boni, Pawel Muranski, Luis Sanchez-Perez, Douglas C. Palmer, Zhiya Yu, Paul A. Antony, Luca Gattinoni, Steven A. Rosenberg, and Nicholas P. Restifo

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CCR Focus Cover

Imaging Update: New Windows, New Views
June 15, 2007
Guest Editor: Ronald Blasberg, 13 (12) : 3435–3759

From the Editor
Susan E. Bates

Imaging Update: New Windows, New Views
Ronald G. Blasberg

Imaging Tumor Vascular Heterogeneity and Angiogenesis using Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Alan Jackson, James P.B. O'Connor, Geoff J.M. Parker, and Gordon C. Jayson

Tumor-Specific Positron Emission Tomography Imaging in Patients: [18F] Fluorodeoxyglucose and Beyond
David A. Mankoff, Janet F. Eary, Jeanne M. Link, Mark Muzi, Joseph G. Rajendran, Alexander M. Spence, and Kenneth A. Krohn

Nuclear Imaging Probes: from Bench to Bedside
Hans-Jürgen Wester

Spatio-Temporal Control of Gene Expression and Cancer Treatment Using Magnetic Resonance Imaging-Guided Focused Ultrasound
Chrit T.W. Moonen

Whole-Body Optical Imaging in Animal Models to Assess Cancer Development and Progression
Eric L. Kaijzel, Gabri van der Pluijm, and Clemens W.G.M. Löwik

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CCR Focus Cover

CNS Metastasis: An Old Problem in a New Guise
March 15, 2007
Guest Editor: Jo Anne Zukewski, 13 (6) : 1623–1946

From the Editor
Susan E. Bates

CNS Metastasis: An Old Problem in a New Guise
Jeanny B. Aragon-Ching and Jo Anne Zujewski

Brain Metastases: The HER2 Paradigm
Nancy U. Lin and Eric P. Winer

The Biology of Metastasis to a Sanctuary Site
Diane Palmieri, Ann F. Chambers, Brunhilde Felding-Habermann, Suyun Huang, and Patricia S. Steeg

The Blood-Brain Barrier and Cancer: Transporters, Treatment, and Trojan Horses
John F. Deeken and Wolfgang Löscher

Targeted Therapy for Brain Metastases: Improving the Therapeutic Ratio
Rakesh R. Patel and Minesh P. Mehta

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