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### Scope

Clinical Cancer Research publishes innovative clinical and translational cancer research studies that bridge the laboratory and the clinic. The Journal is especially interested in clinical trials evaluating new treatments, accompanied by research on pharmacology, and molecular alterations or biomarkers that predict response or resistance to treatment. The Journal also prioritizes laboratory and animal studies of new drugs and molecule-targeted agents with the potential to lead to clinical trials, and studies of targetable mechanisms of oncogenesis, progression of the malignant phenotype, and metastatic disease.

Specific areas of interest include clinical and translational research in targeted therapies; mechanisms of drug sensitivity and resistance; pharmacogenetics and pharmacogenomics; personalized medicine; novel applications of bioinformatics and biostatistics; immunotherapy and clinical immunology; gene therapy; radiobiology and radiation oncology; large-scale molecular characterization of human tumors; diagnostic biomarkers; innovative imaging and other novel methods with potential applicability to clinical investigation; clinical genetics; and detection of minimal disease.

### Manuscript Submission

Clinical Cancer Research welcomes submissions of primary research, review and commentary article types as well as letters to the editor. . For descriptions and length requirements of the article types available to submitting authors, see the journal’s Categories of Articles.

The AACR Journals all use a similar Editorial Process and adhere to the same overarching Editorial Policies, both of which are detailed in the Instructions for Authors. These instructions contain important guidelines on authorship, publishing ethics, availability of materials and data, and data analysis and reporting. Authors should be familiar with these instructions prior to submitting their work to the journal.

Manuscripts are stringently reviewed for high standards of scientific merit, and only those that report results of novel, timely, and broadly-significant research are accepted for publication. Please note that Clinical Cancer Research does not consider appeals.

Submit your article to Clinical Cancer Research

### Journal Metrics

For detailed metrics about Clinical Cancer Research and the other AACR journals see the AACR Journals Metrics.

### Editors and Editorial Board

Editorial oversight of Clinical Cancer Research and decisions on manuscripts submitted to the journal are the responsibility of the Editor-in-Chief and Executive Editor.

Material published in Clinical Cancer Research is covered and protected by copyright. Authors who wish to publish in the journal must formally transfer copyright to the AACR, but are granted considerable reuse rights. The final typeset version of every published article is rendered freely accessible 12 months after publication. Authors who prefer for their article to be immediately freely accessible online may make this selection by paying an additional fee through the AACR AuthorChoice option. In addition, the AACR assists authors in satisfying major funder Open Access archiving mandates by depositing the accepted author version of their article in a designated public repository. For additional details about all these topics, see Copyright, Permissions and Access.

### Publication Fees

To defray publication costs and to support other AACR programs, publication in Clinical Cancer Research involves the payment of a fixed publication fee and an additional fee for any color figures. If no financial support exists, authors may apply for a waiver of the fixed publication fee at the time of submission. See Publication Fees for further details.

### Journal Information

Clinical Cancer Research (CCR) (Print ISSN: 1078-0432; Online ISSN: 1557-3265) is published twice a month, one volume/year, by the American Association for Cancer Research, Inc. (AACR).

Clinical Cancer Research is abstracted and/or indexed in MEDLINE, Current Contents/Clinical Medicine, Science Citation Index, Scopus, and Web of Science.

The journal is printed on paper that meets the requirements of ANSI/NISO Z39.48-1992 (Permanence of Paper).

### Back Issues and Single Copy Sales

Subject to availability, single or back issues of Clinical Cancer Research may be purchased for $60 per copy in the U.S. or$65 per copy outside the U.S. For more information, contact:

AACR Publications Sales & Marketing Department
American Association for Cancer Research
615 Chestnut Street, 17th Floor