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Clinical Trials: Targeted Therapy December 4 2023
Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma
Santosh Kesari; Naveed Wagle; Jose A. Carrillo; Akanksha Sharma; Minhdan Nguyen; Judy Truong; Jaya M. Gill; Raffi Nersesian; Natsuko Nomura; Elnaz Rahbarlayegh; Garni Barkhoudarian; Walavan Sivakumar; Daniel F. Kelly; Howard Krauss; Matias A. Bustos; Dave S.B. Hoon; Lars Anker; Arun S. Singh; Kamalesh K. Sankhala; Tiffany M. Juarez
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy December 4 2023
Combined Vorinostat and Chloroquine Inhibit Sodium–Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo
Martin L. Read; Katie Brookes; Ling Zha; Selvambigai Manivannan; Jana Kim; Merve Kocbiyik; Alice Fletcher; Caroline M. Gorvin; George Firth; Gilbert O. Fruhwirth; Juan P. Nicola; Sissy Jhiang; Matthew D. Ringel; Moray J. Campbell; Kavitha Sunassee; Philip J. Blower; Kristien Boelaert; Hannah R. Nieto; Vicki E. Smith; Christopher J. McCabe
Clin Cancer Res (2023)
Clinical Trials: Targeted Therapy December 4 2023
Olaparib plus Durvalumab, with or without Bevacizumab, as Treatment in PARP Inhibitor-Naïve Platinum-Sensitive Relapsed Ovarian Cancer: A Phase II Multi-Cohort Study
Yvette Drew; Jae-Weon Kim; Richard T. Penson; David M. O'Malley; Christine Parkinson; Patricia Roxburgh; Ruth Plummer; Seock-Ah Im; Martina Imbimbo; Michelle Ferguson; Ora Rosengarten; Neeltje Steeghs; Min Hwan Kim; Einav Gal-Yam; Daliah Tsoref; Jae-Hoon Kim; Benoit You; Maja De Jonge; Roy Lalisang; Eelke Gort; Sara Bastian; Kassondra Meyer; Laura Feeney; Nigel Baker; Mei-Lin Ah-See; Susan M. Domchek; Susana Banerjee; for the MEDIOLA Investigators
Clin Cancer Res (2023)
Precision Medicine and Imaging December 4 2023
Tumor Volume Growth Rates and Doubling Times during Active Surveillance of IDH-mutant Low-Grade Glioma
Ankush Bhatia; Raquel Moreno; Anne S. Reiner; Subhiksha Nandakumar; Henry S. Walch; Teena M. Thomas; Philip J. Nicklin; Ye Choi; Anna Skakodub; Rachna Malani; Vivek Prabhakaran; Pallavi Tiwari; Maria Diaz; Katherine S. Panageas; Ingo K. Mellinghoff; Tejus A. Bale; Robert J. Young
Clin Cancer Res (2023)
Precision Medicine and Imaging December 4 2023
Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study
Hisham Mehanna; Davy Rapozo; Sandra V. von Zeidler; Kevin J. Harrington; Stuart C. Winter; Andrew Hartley; Paul Nankivell; Andrew G. Schache; Philip Sloan; Edward W. Odell; Selvam Thavaraj; Keith D. Hunter; Ketan A. Shah; Gareth J. Thomas; Anna Long; Rasoul Amel-Kashipaz; Rachel M. Brown; Brendan Conn; Gillian L. Hall; Paul Matthews; Justin Weir; Yen Yeo; Miranda Pring; Catharine M.L. West; James McCaul; Pawel Golusinski; Alice Sitch; Rachel Spruce; Nikolaos Batis; Jennifer L. Bryant; Jill M. Brooks; Terence M. Jones; Francesca Buffa; Syed Haider; Max Robinson
Clin Cancer Res (2023)
Research Briefs: Clinical Trial Brief Reports December 4 2023
A Phase II Basket Trial of Dual Anti–CTLA-4 and Anti–PD-1 Blockade in Rare Tumors (DART SWOG 1609 Cohort 47) in Patients with Gestational Trophoblastic Neoplasia
Sandip P. Patel; Megan Othus; Young Kwang Chae; Michael J. Dennis; Sarah Gordon; David Mutch; Wolfram Samlowski; William R. “Rusty” Robinson; Elad Sharon; Christopher Ryan; Gabby Lopez; Melissa Plets; Charles Blanke; Razelle Kurzrock
Clin Cancer Res (2023)
CCR Translations December 4 2023
PRESSING Need of Precision Care in HER2-Positive Colorectal Cancer: The ELEPHANT in the Room
Clin Cancer Res (2023)
CCR Translations December 4 2023
Exploiting Iron Metabolism as a Therapeutic Vulnerability in Glioblastoma
Clin Cancer Res (2023)
Perspective December 1 2023
Backfilling Patients in Phase I Dose Escalation Trials Using Bayesian Optimal Interval Design (BOIN)
Clin Cancer Res (2023)
Research Briefs: Precision Medicine and Therapeutics December 1 2023
TROP2 is associated with primary resistance to immune checkpoint inhibition in patients with advanced non-small cell lung cancer
Alban Bessede; Florent Peyraud; Benjamin Besse; Sophie Cousin; Mathilde Cabart; François Chomy; Christophe Rey; Oren Lara; Ophélie Odin; Imane Nafia; Lucile Vanhersecke; Fabrice Barlesi; Jean-Philippe Guégan; Antoine Italiano
Clin Cancer Res (2023)
Clinical Trial Brief Report December 1 2023
Evaluation of the SSTR2-targeted radiopharmaceutical 177Lu-DOTATATE and SSTR2-specific 68Ga-DOTATATE PET as imaging biomarker in patients with intracranial meningioma
Sylvia C. Kurz; Elcin Zan; Christine Cordova; Andrea B. Troxel; Marissa Barbaro; Joshua S. Silverman; Matija Snuderl; David Zagzag; Douglas Kondziolka; John G. Golfinos; Andrew S. Chi; Erik P. Sulman
Clin Cancer Res (2023)
Research Article December 1 2023
Aneuploidy Landscape in Precursors of Ovarian Cancer
Yeh Wang; Christopher Douville; Yen-Wei Chien; Brant G. Wang; Chi-Long Chen; Andre Pinto; Saron Ann. Smith; Ronny Drapkin; M. Herman Chui; Tricia Numan; Russell Vang; Nickolas Papadopoulos; Tian-Li Wang; Ie-Ming Shih
Clin Cancer Res (2023)
CCR Translations December 1 2023
New T-cell therapies for brain metastasis, CD133 in the driver’s seat
Clin Cancer Res (2023)
CCR Translations December 1 2023
Pancreatic Cancer’s PD1-roadblock: When T-cell reinvigoration is not enough
Clin Cancer Res (2023)
Research Article November 30 2023
Clinical and Immunologic Features of Germline Pathogenic Variant (gPV) Positive Patients with Melanoma
Alan Shen; Michelle Arbesman; Roshan Lodha; Patricia Rayman; Brandon Bungo; Ying Ni; Timothy Chan; Brian Gastman; Jennifer Ko; C. Marcela Diaz-Montero; Joshua Arbesman; Pauline Funchain
Clin Cancer Res (2023)
Research Article November 30 2023
Clinical Benefit of Avapritinib in KIT-Mutant Gastrointestinal Stromal Tumors: A Post Hoc Analysis of the Phase I NAVIGATOR and Phase I/II CS3007-001 Studies
Michael C. Heinrich; Xinhua Zhang; Robin L. Jones; Suzanne George; César Serrano; Yanhong Deng; Sebastian Bauer; Shirong Cai; Xin Wu; Yongjian Zhou; Kaixiong Tao; Zhichao Zheng; Jun Zhang; Yuehong Cui; Hui Cao; Meining Wang; Jin Hu; Jason Yang; Jian Li; Lin Shen
Clin Cancer Res (2023)
Clinical Trials: Targeted Therapy November 28 2023
Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma
Daniel P. Petrylak; Bernhard J. Eigl; Saby George; Elisabeth I. Heath; Sebastien J. Hotte; David D. Chism; Lisle M. Nabell; Joel Picus; Susanna Y. Cheng; Leonard J. Appleman; Guru P. Sonpavde; Alicia K. Morgans; Pourya Pourhosseini; Ruishan Wu; Laura Standley; Ruslan Croitoru; Evan Y. Yu
Clin Cancer Res (2023)
Clinical Trials: Targeted Therapy November 28 2023
Overall Survival and Exploratory Biomarker Analyses of Abemaciclib plus Trastuzumab with or without Fulvestrant versus Trastuzumab plus Chemotherapy in HR+, HER2+ Metastatic Breast Cancer Patients
Sara M. Tolaney; Shom Goel; Jorge Nadal; Hannelore Denys; Manuel R. Borrego; Lacey M. Litchfield; Jiangang Liu; Adams K. Appiah; Yanyun Chen; Fabrice André
Clin Cancer Res (2023)
Precision Medicine and Imaging November 28 2023
PET/CT Biomarkers Enable Risk Stratification of Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma Enrolled in the LOTIS-2 Clinical Trial
Juan Pablo Alderuccio; Isildinha M. Reis; Mehdi Hamadani; Muthiah Nachiappan; Salman Leslom; Brad S. Kahl; Weiyun Z. Ai; John Radford; Melhem Solh; Kirit M. Ardeshna; Brian T. Hess; Matthew A. Lunning; Pier Luigi Zinzani; Anastasios Stathis; Carmelo Carlo-Stella; Izidore S. Lossos; Paolo F. Caimi; Sunwoo Han; Fei Yang; Russ A. Kuker; Craig H. Moskowitz
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 28 2023
FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
Phillip M. Pifer; Liangpeng Yang; Manish Kumar; Tongxin Xie; Mitchell Frederick; Andrew Hefner; Beth Beadle; David Molkentine; Jessica Molkentine; Annika Dhawan; Mohamed Abdelhakiem; Abdullah A. Osman; Brian J. Leibowitz; Jeffrey N. Myers; Curtis R. Pickering; Vlad C. Sandulache; John Heymach; Heath D. Skinner
Clin Cancer Res (2023)
Precision Medicine and Imaging November 28 2023
Comprehensive DNA Methylation Profiling of Medullary Thyroid Carcinoma: Molecular Classification, Potential Therapeutic Target, and Classifier System
Cenkai Shen; Xiao Shi; Duo Wen; Yuqing Zhang; Yuxin Du; Yu Zhang; Ben Ma; Haitao Tang; Min Yin; Naisi Huang; Tian Liao; Ting-Ting Zhang; Chang’e Kong; Wenjun Wei; Qinghai Ji; Yu Wang
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 28 2023
Tumor-Infiltrating CD103+ Tissue-Resident Memory T Cells and CD103−CD8+ T Cells in HNSCC Are Linked to Outcome in Primary but not Metastatic Disease
Adrian von Witzleben; Matthew Ellis; Gareth J. Thomas; Thomas K. Hoffmann; Richard Jackson; Simon Laban; Christian H. Ottensmeier
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 28 2023
Landscape of Baseline and Acquired Genomic Alterations in Circulating Tumor DNA with Abemaciclib Alone or with Endocrine Therapy in Advanced Breast Cancer
Matthew P. Goetz; Erika P. Hamilton; Mario Campone; Sara A. Hurvitz; Javier Cortes; Stephen Johnston; Antonio Llombart-Cussac; Peter A. Kaufman; Masakazu Toi; Guy Jerusalem; Hillary Graham; Hong Wang; Valerie M. Jansen; Lacey M. Litchfield; Miguel Martin
Clin Cancer Res (2023)
Review November 28 2023
Facts and Hopes in Neoadjuvant Immunotherapy: Current Approvals and Emerging Evidence
Clin Cancer Res (2023)
Review November 28 2023
Translational Aspects of Epithelioid Sarcoma: Current Consensus
Thomas G.P. Grünewald; Sophie Postel-Vinay; Robert T. Nakayama; Noah E. Berlow; Andrea Bolzicco; Vincenzo Cerullo; Josephine K. Dermawan; Anna Maria Frezza; Antoine Italiano; Jia xiang Jin; Francois Le Loarer; Javier Martin-Broto; Andrew Pecora; Antonio Perez-Martinez; Yuen Bun Tam; Franck Tirode; Annalisa Trama; Sandro Pasquali; Mariagrazia Vescia; Lukas Wortmann; Michael Wortmann; Akihiko Yoshida; Kim Webb; Paul H. Huang; Charles Keller; Cristina R. Antonescu
Clin Cancer Res (2023)
Review November 28 2023
Fine-Tuning Adjuvant Endocrine Therapy for Early-Stage Breast Cancer: An Expert Consensus on Open Issues for Future Research
Fabio Conforti; Laura Pala; Tommaso De Pas; Emma Zattarin; Chiara Catania; Emilia Cocorocchio; Giovanna Rossi; Daniele Laszlo; Marco Colleoni; Alberto Zambelli; Gabriel N. Hortobagyi; Javier Cortes; Martine J. Piccart; Mitch Dowsett; Richard D. Gelber; Giuseppe Viale
Clin Cancer Res (2023)
Research Article November 27 2023
Modulating gut microbiota prevents anastomotic leak to reduce local implantation and dissemination of colorectal cancer cells after surgery
Roy Hajjar; Manon Oliero; Gabriela Fragoso; Ayodeji Samuel. Ajayi; Ahmed Amine Alaoui; Hervé Vennin Rendos; Annie Calvé; Thibault Cuisiniere; Claire Gerkins; Sophie Thérien; Nassima Taleb; François Dagbert; Herawaty Sebajang; Rasmy Loungnarath; Frank Schwenter; Richard Ratelle; Ramses Wassef; Eric De Broux; Carole Richard; Manuela M. Santos
Clin Cancer Res (2023)
CCR Drug Updates November 27 2023
FDA Approval Summary: Ivosidenib in Combination with Azacitidine for Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia with an IDH1 Mutation
Ashley Woods; Kelly J. Norsworthy; Xin Wang; Jonathon Vallejo; Edwin C.Y. Chow; Ruo-Jing Li; Jielin Sun; Rosane Charlab; Xiling Jiang; Richard Pazdur; Marc R. Theoret; R. Angelo de Claro
Clin Cancer Res (2023)
Research Article November 22 2023
Platinum-based chemotherapy attenuates the effector response of CD8 T cells to concomitant PD-1 blockade
Annapaola Mariniello; Tahseen H. Nasti; Daniel Y. Chang; Masao Hashimoto; Sakshi Malik; Daniel McManus; Judong Lee; Donald McGuire; Maria A. Cardenas; Pablo Umana; Valeria Nicolini; Rustom Antia; Ananya Saha; Zachary Buchwald; Haydn Kissick; Ehsan Ghorani; Silvia Novello; Dario Sangiolo; Giorgio V. Scagliotti; Suresh S. Ramalingam; Rafi Ahmed
Clin Cancer Res (2023)
Research Article November 22 2023
Development of resistance to type II JAK2 inhibitors in MPN depends on AXL kinase and is targetable
Tamara Codilupi; Jakub Szybinski; Stefanie Arunasalam; Sarah Jungius; Andrew C. Dunbar; Simona Stivala; Sime Brkic; Camille Albrecht; Lenka Vokalova; Julie L. Yang; Katarzyna Buczak; Nilabh Ghosh; Jakob R. Passweg; Alicia Rovo; Anne Angelillo-Scherrer; Dmitry Pankov; Stephan Dirnhofer; Ross L. Levine; Richard Koche; Sara C. Meyer
Clin Cancer Res (2023)
Research Article November 22 2023
A Phase I/II Study of GSK525762 Combined With Fulvestrant in Patients With Hormone Receptor-Positive/HER2-Negative (HR+/HER2−) Advanced or Metastatic Breast Cancer
David W. Cescon; John Hilton; Serafín Morales Murilo; Rachel M. Layman; Timothy Pluard; Belinda Yeo; In Hae Park; Louise Provencher; Sung-Bae Kim; Young-Hyuck Im; Anastasia Wyce; Anu Shilpa Krishnatry; Kirsty Hicks; Qu Zhang; Olena Barbash; Ahmed Khaled; Thierry Horner; Arindam Dhar; Mafalda Oliveira; Joseph A. Sparano
Clin Cancer Res (2023)
CCR Translations November 21 2023
The Dance Between Tumor Molecular Biology and Antitumor Immune Response
Clin Cancer Res (2023)
Precision Medicine and Imaging November 21 2023
Intraoperative Integrated Diagnostic System for Malignant Central Nervous System Tumors
Takahiro Hayashi; Kensuke Tateishi; Shinichiro Matsuyama; Hiromichi Iwashita; Yohei Miyake; Akito Oshima; Hirokuni Honma; Jo Sasame; Katsuhiro Takabayashi; Kyoka Sugino; Emi Hirata; Naoko Udaka; Yuko Matsushita; Ikuma Kato; Hiroaki Hayashi; Taishi Nakamura; Naoki Ikegaya; Yutaro Takayama; Masaki Sonoda; Chihiro Oka; Mitsuru Sato; Masataka Isoda; Miyui Kato; Kaho Uchiyama; Tamon Tanaka; Toshiki Muramatsu; Shigeta Miyake; Ryosuke Suzuki; Mutsumi Takadera; Junya Tatezuki; Junichi Ayabe; Jun Suenaga; Shigeo Matsunaga; Kosuke Miyahara; Hiroshi Manaka; Hidetoshi Murata; Takaakira Yokoyama; Yoshihide Tanaka; Takashi Shuto; Koichi Ichimura; Shingo Kato; Shoji Yamanaka; Daniel P. Cahill; Satoshi Fujii; Ganesh M. Shankar; Tetsuya Yamamoto
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 21 2023
Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy
Nina Zila; Ossia M. Eichhoff; Irene Steiner; Thomas Mohr; Andrea Bileck; Phil F. Cheng; Alexander Leitner; Ludovic Gillet; Tatjana Sajic; Sandra Goetze; Betty Friedrich; Patricia Bortel; Johanna Strobl; René Reitermaier; Sabrina A. Hogan; Julia M. Martínez Gómez; Ramon Staeger; Felix Tuchmann; Sophie Peters; Georg Stary; Mario Kuttke; Adelheid Elbe-Bürger; Christoph Hoeller; Rainer Kunstfeld; Wolfgang Weninger; Bernd Wollscheid; Reinhard Dummer; Lars E. French; Christopher Gerner; Ruedi Aebersold; Mitchell P. Levesque; Verena Paulitschke
Clin Cancer Res (2023)
Precision Medicine and Imaging November 21 2023
A Fully Automated Deep-Learning Model for Predicting the Molecular Subtypes of Posterior Fossa Ependymomas Using T2-Weighted Images
Dan Cheng; Zhizheng Zhuo; Jiang Du; Jinyuan Weng; Chengzhou Zhang; Yunyun Duan; Ting Sun; Minghao Wu; Min Guo; Tiantian Hua; Ying Jin; Boyang Peng; Zhaohui Li; Mingwang Zhu; Maliha Imami; Chetan Bettegowda; Haris Sair; Harrison X. Bai; Frederik Barkhof; Xing Liu; Yaou Liu
Clin Cancer Res (2023)
Precision Medicine and Imaging November 21 2023
PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax
Antoine Pinton; Lucien Courtois; Charlotte Doublet; Aurélie Cabannes-Hamy; Guillaume Andrieu; Charlotte Smith; Estelle Balducci; Agata Cieslak; Aurore Touzart; Mathieu Simonin; Véronique Lhéritier; Françoise Huguet; Marie Balsat; Hervé Dombret; Philippe Rousselot; Salvatore Spicuglia; Elizabeth Macintyre; Nicolas Boissel; Vahid Asnafi
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 21 2023
Landscape of Clinical Resistance Mechanisms to FGFR Inhibitors in FGFR2-Altered Cholangiocarcinoma
Qibiao Wu; Haley Ellis; Giulia Siravegna; Alexa G. Michel; Bryanna L. Norden; Ferran Fece de la Cruz; Eranga Roshan Balasooriya; Yuanli Zhen; Vanessa S. Silveira; Jianwe Che; Ryan B. Corcoran; Nabeel Bardeesy
Clin Cancer Res (2023)
Special Report November 21 2023
Novel Approach to Accelerate Lung Cancer Research: Lung-MAP and the Potential of Public-Private Partnerships
Clin Cancer Res (2023)
CCR Translations November 21 2023
Uncovering the Potential of CD40 Agonism to Enhance Immune Checkpoint Blockade
Clin Cancer Res (2023)
Research Article November 20 2023
A Phase I Study of the CDK4/6 Inhibitor, Palbociclib in Combination with Cetuximab and Radiotherapy (IMRT) for Locally Advanced Head and Neck Squamous Cell Carcinoma
Nuttapong Ngamphaiboon; Poompis Pattaranutaporn; Somthawin Lukerak; Teerada Siripoon; Artit Jinawath; Lalida Arsa; Prapimporn Ch. Shantavasinkul; Naphat Taonam; Narumol Trachu; Natini Jinawath; Arpakorn Kositwattanarerk; Thiparom Sananmuang; Chuleeporn Jiarpinitnun
Clin Cancer Res (2023)
Research Article November 20 2023
Phase 1 study of Elraglusib (9-ING-41), a glycogen synthase kinase-3b inhibitor, as monotherapy or combined with chemotherapy in patients with advanced malignancies
Benedito A. Carneiro; Ludimila Cavalcante; Devalingam Mahalingam; Anwaar Saeed; Howard Safran; Wen Wee Ma; Andrew L. Coveler; Steven Powell; Bruno Bastos; Elizabeth Davis; Vaibhav Sahai; William Mikrut; James Longstreth; Sheri Smith; Taylor Weiskittel; Hu Li; Brittany A. Borden; R. Donald Harvey; Solmaz Sahebjam; Andres Cervantes; Austin Koukol; Andrew P. Mazar; Neeltje Steeghs; Razelle Kurzrock; Francis J. Giles; Pamela Munster
Clin Cancer Res (2023)
Research Article November 20 2023
A Phase 1b First-In-Patient Study Assessing the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ponsegromab in Participants with Cancer and Cachexia
Jeffrey Crawford; Roberto A. Calle; Susie M. Collins; Yan Weng; Shannon L. Lubaczewski; Clare Buckeridge; Ellen Q. Wang; Magdalena A. Harrington; Anil Tarachandani; Michelle I. Rossulek; James H. Revkin
Clin Cancer Res (2023)
Research Article November 20 2023
Selective DNA-PK inhibition enhances chemotherapy and ionizing radiation activity in soft-tissue sarcomas
Audrey Laroche-Clary; Coralie Josensi; Marie-Alix Derieppe; Sarah Belhomme; Véronique Vendrely; Raul Perret; Elaine Cadogan; Antoine Italiano
Clin Cancer Res (2023)
Translational Cancer Mechanisms and Therapy November 20 2023
A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells
Veronica Calvo; Wei Zheng; Anna Adam-Artigues; Kirk A. Staschke; Xin Huang; Julie F. Cheung; Ana Rita Nobre; Sho Fujisawa; David Liu; Maria Fumagalli; David Surguladze; Michael E. Stokes; Ari Nowacek; Mark Mulvihill; Eduardo F. Farias; Julio A. Aguirre-Ghiso
Clin Cancer Res (2023)
Research Article November 17 2023
Phase I/IIa trial in advanced pancreatic ductal adenocarcinoma treated with cytotoxic drug-packaged, EGFR-targeted nanocells and glycolipid-packaged nanocells
Vinod Ganju; Gavin Marx; Scott Pattison; Nancy B. Amaro-Mugridge; Jing-Ting Zhao; Bryan R.G. Williams; Jennifer A. MacDiarmid; Himanshu Brahmbhatt
Clin Cancer Res (2023)
Research Article November 16 2023
First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
Nehal J. Lakhani; Drew Rasco; Hengbang Wang; Lichuang Men; Eric Liang; Tommy Fu; Mary C. Collins; Ping Min; Yan Yin; Matthew S. Davids; Dajun Yang; Yifan Zhai
Clin Cancer Res (2023)
Research Article November 15 2023
SAR-096: Phase II clinical trial of ribociclib in combination with everolimus in advanced dedifferentiated liposarcoma (DDL), and leiomyosarcoma (LMS)
Sujana Movva; Sahar Matloob; Elizabeth A. Handorf; Edwin Choy; Priscilla Merriam; Douglas B. Flieder; Kathy Q. Cai; Yan Zhou; Eric D. Tetzlaff; Cheyenne Pagan; Emma Barker; Rosanna Veggeberg; Delia Zumpano; Lori Rink; Margaret von Mehren; Suzanne George
Clin Cancer Res (2023)
Research Article November 15 2023
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1
Anna D. Staniszewska; Domenic Pilger; Sonja J. Gill; Kunzah Jamal; Natacha Bohin; Sofia Guzzetti; Jacob Gordon; Gregory Hamm; Gill Mundin; Giuditta Illuzzi; Andy Pike; Lisa McWilliams; Gareth Maglennon; Jonathan Rose; Glen Hawthorne; Miguel Cortes Gonzalez; Christer Halldin; Peter Johnström; Magnus Schou; Susan E. Critchlow; Stephen Fawell; Jeffrey W. Johannes; Elisabetta Leo; Barry R. Davies; Sabina Cosulich; Jann N. Sarkaria; Mark J. O'Connor; Petra Hamerlik
Clin Cancer Res (2023)
Research Article November 15 2023
Detection of recurrence through microRNA-371a-3p serum levels in a follow-up of stage I testicular germ cell tumors in the DRKS-00019223 study
Gazanfer Belge; Cansu Dumlupinar; Tim Nestler; Markus Klemke; Peter Törzsök; Emanuela Trenti; Renate Pichler; Wolfgang Loidl; Yue Che; Andreas Hiester; Cord Matthies; Martin Pichler; Pia Paffenholz; Luis Kluth; Mike Wenzel; Jörg Sommer; Julia Heinzelbecker; Philipp Schriefer; Alexander Winter; Friedemann Zengerling; Mario Wolfgang. Kramer; Marie Lengert; Jana Frey; Axel Heidenreich; Christian Wülfing; Arlo Radtke; Klaus-Peter Dieckmann
Clin Cancer Res (2023)
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