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Editorial

Coregulator Expression and Breast Cancer: Improving the Predictive Power of Estrogen Receptor α

View articletitled, Coregulator Expression and Breast Cancer: Improving the Predictive Power of Estrogen Receptor α

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Molecular Therapeutics: Is One Promiscuous Drug against Multiple Targets Better than Combinations of Molecule-specific Drugs?1

Carlos L. Arteaga

Extract

View articletitled, Molecular Therapeutics: Is One Promiscuous Drug against Multiple Targets Better than Combinations of Molecule-specific Drugs?<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Is Another Bcr-Abl Inhibitor Needed for Chronic Myelogenous Leukemia?

Edward A. Sausville

Extract

View articletitled, Is Another Bcr-Abl Inhibitor Needed for Chronic Myelogenous Leukemia?

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Minireview

Is the Measurement of Thymidylate Synthase to Determine Suitability for Treatment with 5-Fluoropyrimidines Ready for Prime Time?1

Joseph R. Bertino; Debabrata Banerjee

Extract

View articletitled, Is the Measurement of Thymidylate Synthase to Determine Suitability for Treatment with 5-Fluoropyrimidines Ready for Prime Time?<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Need to Embrace Molecular Profiling of Tumor Cells in Prostate and Bladder Cancer 1

Brian J. Duggan; John J. McKnight; Kate E. Williamson; Maurice Loughrey; Declan O’Rourke; Peter W. Hamilton; Samuel R. Johnston; Claude C. Schulman; Alexandre R. Zlotta

Abstract

View articletitled, The Need to Embrace Molecular Profiling of Tumor Cells in Prostate and Bladder Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Biology Behind

Understanding the Molecular Basis of Imatinib Mesylate Therapy in Chronic Myelogenous Leukemia and the Related Mechanisms of Resistance 1: Commentary re: A. N. Mohamed et al., The Effect of Imatinib Mesylate on Patients with Philadelphia Chromosome-positive Chronic Myeloid Leukemia with Secondary Chromosomal Aberrations. Clin. Cancer Res., 9: 1333–1337, 2003.

Guido Marcucci; Danilo Perrotti; Michael A. Caligiuri

Extract

View articletitled, Understanding the Molecular Basis of Imatinib Mesylate Therapy in Chronic Myelogenous Leukemia and the Related Mechanisms of Resistance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>: Commentary re: A. N. Mohamed et al., The Effect of Imatinib Mesylate on Patients with Philadelphia Chromosome-positive Chronic Myeloid Leukemia with Secondary Chromosomal Aberrations. Clin. Cancer Res., 9: 1333–1337, 2003.

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Advances in Brief

Molecular Oncology, Markers, Clinical Correlates

Combined Vascular Endothelial Growth Factor and TP53 Status Predicts Poor Response to Tamoxifen Therapy in Estrogen Receptor-positive Advanced Breast Cancer 1

Els M. J. J. Berns; Jan G. M. Klijn; Maxime P. Look; Nicolai Grebenchtchikov; Rolf Vossen; Harry Peters; Anneke Geurts-Moespot; Henk Portengen; Iris L. van Staveren; Marion E. Meijer-van Gelder; Bert Bakker; Fred C. G. J. Sweep; John A. Foekens

Abstract

View articletitled, Combined Vascular Endothelial Growth Factor and TP53 Status Predicts Poor Response to Tamoxifen Therapy in Estrogen Receptor-positive Advanced Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression Analysis of Estrogen Receptor α Coregulators in Breast Carcinoma: Evidence That NCOR1 Expression Is Predictive of the Response to Tamoxifen 1

Igor Girault; Florence Lerebours; Samira Amarir; Sengül Tozlu; Michèle Tubiana-Hulin; Rosette Lidereau; Ivan Bièche

Abstract

View articletitled, Expression Analysis of Estrogen Receptor α Coregulators in Breast Carcinoma: Evidence That NCOR1 Expression Is Predictive of the Response to Tamoxifen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Experimental Therapeutics, Preclinical Pharmacology

A Novel Pyridopyrimidine Inhibitor of Abl Kinase Is a Picomolar Inhibitor of Bcr-abl-driven K562 Cells and Is Effective against STI571-resistant Bcr-abl Mutants 1

David R. Huron; Mercedes E. Gorre; Alan J. Kraker; Charles L. Sawyers; Neal Rosen; Mark M. Moasser

Abstract

View articletitled, A Novel Pyridopyrimidine Inhibitor of Abl Kinase Is a Picomolar Inhibitor of Bcr-abl-driven K562 Cells and Is Effective against STI571-resistant Bcr-abl Mutants<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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ZD1839, a Specific Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor, Induces the Formation of Inactive EGFR/HER2 and EGFR/HER3 Heterodimers and Prevents Heregulin Signaling in HER2-overexpressing Breast Cancer Cells 1

Judit Anido; Pablo Matar; Joan Albanell; Marta Guzmán; Federico Rojo; Joaquin Arribas; Steve Averbuch; Jose Baselga

Abstract

View articletitled, ZD1839, a Specific Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor, Induces the Formation of Inactive EGFR/HER2 and EGFR/HER3 Heterodimers and Prevents Heregulin Signaling in HER2-overexpressing Breast Cancer Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Long-Term Survival of Dogs with Advanced Malignant Melanoma after DNA Vaccination with Xenogeneic Human Tyrosinase: A Phase I Trial 1

Philip J. Bergman; Joanne McKnight; Andrew Novosad; Sarah Charney; John Farrelly; Diane Craft; Michelle Wulderk; Yusuf Jeffers; Michel Sadelain; Ann E. Hohenhaus; Neil Segal; Polly Gregor; Manuel Engelhorn; Isabelle Riviere; Alan N. Houghton; Jedd D. Wolchok

Abstract

View articletitled, Long-Term Survival of Dogs with Advanced Malignant Melanoma after DNA Vaccination with Xenogeneic Human Tyrosinase: A Phase I Trial<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Small Interfering RNAs Directed against β-Catenin Inhibit the in Vitro and in Vivo Growth of Colon Cancer Cells 1

Udit N. Verma; Rama M. Surabhi; Aurelia Schmaltieg; Carlos Becerra; Richard B. Gaynor

Abstract

View articletitled, Small Interfering RNAs Directed against β-Catenin Inhibit the in Vitro and in Vivo Growth of Colon Cancer Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regular Articles

Clinical Trials

A Phase I Trial of SD-9427 (Progenipoietin) with a Multipeptide Vaccine for Resected Metastatic Melanoma 1

Vinod Pullarkat; Peter P. Lee; Ronaldo Scotland; Valerie Rubio; Susan Groshen; Conway Gee; Roy Lau; Jolie Snively; Shirley Sian; Susan L. Woulfe; Richard A. Wolfe; Jeffrey S. Weber

Abstract

View articletitled, A Phase I Trial of SD-9427 (Progenipoietin) with a Multipeptide Vaccine for Resected Metastatic Melanoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Phase I Trial of ZD9331, a Water-Soluble, Nonpolyglutamatable, Thymidylate Synthase Inhibitor

Ruth Plummer; Charlotte Rees; Andrew Hughes; Philip Beale; Martin Highley; Jose Trigo; Sathyarathnarn Gokul; Ian Judson; Hilary Calvert; Ann Jackman; Fraser Mitchell; Robert Smith; Edwin Douglass

Abstract

View articletitled, A Phase I Trial of ZD9331, a Water-Soluble, Nonpolyglutamatable, Thymidylate Synthase Inhibitor

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A Phase I Study of Anti-Kinase Insert Domain-containing Receptor Antibody, IMC-1C11, in Patients with Liver Metastases from Colorectal Carcinoma 1

James A. Posey; Thian C. Ng; Baolian Yang; M. B. Khazaeli; Mark D. Carpenter; Floyd Fox; Mike Needle; Harlan Waksal; Albert F. LoBuglio

Abstract

View articletitled, A Phase I Study of Anti-Kinase Insert Domain-containing Receptor Antibody, IMC-1C11, in Patients with Liver Metastases from Colorectal Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Effect of Imatinib Mesylate on Patients with Philadelphia Chromosome-positive Chronic Myeloid Leukemia with Secondary Chromosomal Aberrations

Anwar N. Mohamed; Pamela Pemberton; Jeffrey Zonder; Charles A. Schiffer

Abstract

View articletitled, The Effect of Imatinib Mesylate on Patients with Philadelphia Chromosome-positive Chronic Myeloid Leukemia with Secondary Chromosomal Aberrations

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Phase I Study of Anticolon Cancer Humanized Antibody A33 1

Sydney Welt; Gerd Ritter; Clarence Williams, Jr.; Leonard S. Cohen; Mary John; Achim Jungbluth; Elizabeth A. Richards; Lloyd J. Old; Nancy E. Kemeny

Abstract

View articletitled, Phase I Study of Anticolon Cancer Humanized Antibody A33<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Preliminary Report of a Phase I Study of Combination Chemotherapy and Humanized A33 Antibody Immunotherapy in Patients with Advanced Colorectal Cancer 1

Sydney Welt; Gerd Ritter; Clarence Williams, Jr.; Leonard S. Cohen; Achim Jungbluth; Elizabeth A. Richards; Lloyd J. Old; Nancy E. Kemeny

Abstract

View articletitled, Preliminary Report of a Phase I Study of Combination Chemotherapy and Humanized A33 Antibody Immunotherapy in Patients with Advanced Colorectal Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phase I Trial of Consensus Interferon in Patients with Metastatic Renal Cell Carcinoma: Toxicity and Immunological Effects 1

Thomas E. Hutson; Luis Molto; Tarek Mekhail; Paul Elson; James Finke; Charles Tannenbaum; Ernest Borden; Robert Dreicer; Thomas Olencki; Ronald M. Bukowski

Abstract

View articletitled, Phase I Trial of Consensus Interferon in Patients with Metastatic Renal Cell Carcinoma: Toxicity and Immunological Effects<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Molecular Oncology,Markers,Clinical Correlates

Association of BRCA2 Polymorphism at Codon 784 (Met/Val) with Breast Cancer Risk and Prognosis 1

Makoto Ishitobi; Yasuo Miyoshi; Akiko Ando; Seiichi Hasegawa; Chiyomi Egawa; Yasuhiro Tamaki; Morito Monden; Shinzaburo Noguchi

Abstract

View articletitled, Association of BRCA2 Polymorphism at Codon 784 (Met/Val) with Breast Cancer Risk and Prognosis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Levels of Soluble Vascular Endothelial Growth Factor (VEGF) Receptor 1 in Astrocytic Tumors and Its Relation to Malignancy, Vascularity, and VEGF-A 1

Katrin Lamszus; Ulrike Ulbricht; Jakob Matschke; Marc A. Brockmann; Regina Fillbrandt; Manfred Westphal

Abstract

View articletitled, Levels of Soluble Vascular Endothelial Growth Factor (VEGF) Receptor 1 in Astrocytic Tumors and Its Relation to Malignancy, Vascularity, and VEGF-A<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Experimental Therapeutics,Preclinical Pharmacology

Rapid and Selective Apoptosis in Human Leukemic Cells Induced by Aplidine through a Fas/CD95- and Mitochondrial-mediated Mechanism 1

Consuelo Gajate; Feiyun An; Faustino Mollinedo

Abstract

View articletitled, Rapid and Selective Apoptosis in Human Leukemic Cells Induced by Aplidine through a Fas/CD95- and Mitochondrial-mediated Mechanism<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Research Articles

Molecular Oncology, Markers, Clinical Correlates

Expression of Vascular Endothelial Growth Factor (VEGF)-D and Its Receptor, VEGF Receptor 3, as a Prognostic Factor in Endometrial Carcinoma 1

Yoshihito Yokoyama; D. Stephen Charnock-Jones; Diana Licence; Atsushi Yanaihara; Julie M. Hastings; Cathrine M. Holland; Makoto Emoto; Akiko Sakamoto; Tomomi Sakamoto; Hidetoshi Maruyama; Shigemi Sato; Hideki Mizunuma; Stephen K. Smith

Abstract

View articletitled, Expression of Vascular Endothelial Growth Factor (VEGF)-D and Its Receptor, VEGF Receptor 3, as a Prognostic Factor in Endometrial Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Gene Promoter Hypermethylation in Tumors and Lymph Nodes of Stage I Lung Cancer Patients

Susan V. Harden; Yutaka Tokumaru; William H. Westra; Steven Goodman; Steven A. Ahrendt; Stephen C. Yang; David Sidransky

Abstract

View articletitled, Gene Promoter Hypermethylation in Tumors and Lymph Nodes of Stage I Lung Cancer Patients

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Prognostic Significance of CD20 Expression in Classical Hodgkin Lymphoma: A Clinicopathological Study of 119 Cases 1

Alexandar Tzankov; Jens Krugmann; Falko Fend; Martina Fischhofer; Richard Greil; Stephan Dirnhofer

Abstract

View articletitled, Prognostic Significance of CD20 Expression in Classical Hodgkin Lymphoma: A Clinicopathological Study of 119 Cases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Incidence of Microsatellite Instability in Synchronous Tumors of the Ovary and Endometrium

Catherine Shannon; Judy Kirk; Rebecca Barnetson; Justin Evans; Margaret Schnitzler; Michael Quinn; Neville Hacker; Alex Crandon; Paul Harnett

Abstract

View articletitled, Incidence of Microsatellite Instability in Synchronous Tumors of the Ovary and Endometrium

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KAI1 Metastasis Suppressor Protein Is Down-Regulated during the Progression of Human Endometrial Cancer 1

Fu-Shing Liu; Jin-Tang Dong; Jung-Ta Chen; Yeun-Ting Hsieh; Esther Shih-Chu Ho; Man-Jung Hung; Chien-Hsing Lu; Li-Ching Chiou

Abstract

View articletitled, KAI1 Metastasis Suppressor Protein Is Down-Regulated during the Progression of Human Endometrial Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Topoisomerase IIα Expression Correlates with Survival in Patients with Advanced Hodgkin’s Lymphoma

Mariano Provencio; Cesar Corbacho; Clara Salas; Isabel Millan; Pilar Espana; Felix Bonilla; Santiago Ramon Cajal

Abstract

View articletitled, The Topoisomerase IIα Expression Correlates with Survival in Patients with Advanced Hodgkin’s Lymphoma

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PEA3 Is the Second Ets Family Transcription Factor Involved in Tumor Progression in Ovarian Carcinoma 1

Ben Davidson; Iris Goldberg; Walter H. Gotlieb; Juri Kopolovic; Gilad Ben-Baruch; Reuven Reich

Abstract

View articletitled, PEA3 Is the Second Ets Family Transcription Factor Involved in Tumor Progression in Ovarian Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Activation and Overexpression of Centrosome Kinase BTAK/Aurora-A in Human Ovarian Cancer 1

Tatiana M. Gritsko; Domenico Coppola; June E. Paciga; Lin Yang; Mei Sun; Sue A. Shelley; James V. Fiorica; Santo V. Nicosia; Jin Q. Cheng

Abstract

View articletitled, Activation and Overexpression of Centrosome Kinase BTAK/Aurora-A in Human Ovarian Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Stanniocalcin-1: A Novel Molecular Blood and Bone Marrow Marker for Human Breast Cancer 1

Robert A. Wascher; Kelly T. Huynh; Armando E. Giuliano; Nora M. Hansen; Frederick R. Singer; David Elashoff; Dave S. B. Hoon

Abstract

View articletitled, Stanniocalcin-1: A Novel Molecular Blood and Bone Marrow Marker for Human Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Receptor Activator of Nuclear Factor κB Ligand on Bone Marrow Plasma Cells Correlates with Osteolytic Bone Disease in Patients with Multiple Myeloma

Ulrike Heider; Corinna Langelotz; Christian Jakob; Ivana Zavrski; Claudia Fleissner; Jan Eucker; Kurt Possinger; Lorenz C. Hofbauer; Orhan Sezer

Abstract

View articletitled, Expression of Receptor Activator of Nuclear Factor κB Ligand on Bone Marrow Plasma Cells Correlates with Osteolytic Bone Disease in Patients with Multiple Myeloma

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Promoter Hypermethylation of RASSF1A in Esophageal Squamous Cell Carcinoma 1

Tamotsu Kuroki; Francesco Trapasso; Sai Yendamuri; Ayumi Matsuyama; Hansjuerg Alder; Masaki Mori; Carlo M. Croce

Abstract

View articletitled, Promoter Hypermethylation of RASSF1A in Esophageal Squamous Cell Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Methylation of Cyclin D2 Is Observed Frequently in Pancreatic Cancer but Is Also an Age-related Phenomenon in Gastrointestinal Tissues 1

Hiroyuki Matsubayashi; Norihiro Sato; Noriyoshi Fukushima; Charles J. Yeo; Kimberly M. Walter; Kieran Brune; Fikret Sahin; Ralph H. Hruban; Michael Goggins

Abstract

View articletitled, Methylation of Cyclin D2 Is Observed Frequently in Pancreatic Cancer but Is Also an Age-related Phenomenon in Gastrointestinal Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Significance of Thymidylate Synthase Activity in Renal Cell Carcinoma 1

Yoichi Mizutani; Hiromi Wada; Osamu Yoshida; Masakazu Fukushima; Mitsuo Nonomura; Masahiro Nakao; Tsuneharu Miki

Abstract

View articletitled, Significance of Thymidylate Synthase Activity in Renal Cell Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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O⁶-methyl-guanine-DNA methyltransferase Methylation in Serum and Tumor DNA Predicts Response to 1,3-Bis(2-Chloroethyl)-1-Nitrosourea but not to Temozolamide Plus Cisplatin in Glioblastoma Multiforme 1

Carme Balaña; Jose Luis Ramirez; Miquel Taron; Yannis Roussos; Aurelio Ariza; Rosa Ballester; Carme Sarries; Pedro Mendez; Jose Javier Sanchez; Rafael Rosell

Abstract

View articletitled, O6-methyl-guanine-DNA methyltransferase Methylation in Serum and Tumor DNA Predicts Response to 1,3-Bis(2-Chloroethyl)-1-Nitrosourea but not to Temozolamide Plus Cisplatin in Glioblastoma Multiforme<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Molecular Targets for Tyrosine Kinase Receptor Antagonists in Malignant Endocrine Pancreatic Tumors 1

Marie-Louise H. Fjällskog; Margareta H. Lejonklou; Kjell E. Öberg; Barbro K. Eriksson; Eva T. Janson

Abstract

View articletitled, Expression of Molecular Targets for Tyrosine Kinase Receptor Antagonists in Malignant Endocrine Pancreatic Tumors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Combined Loss of PTEN and p27 Expression Is Associated with Tumor Cell Proliferation by Ki-67 and Increased Risk of Recurrent Disease in Localized Prostate Cancer 1

Ole J. Halvorsen; Svein A. Haukaas; Lars A. Akslen

Abstract

View articletitled, Combined Loss of PTEN and p27 Expression Is Associated with Tumor Cell Proliferation by Ki-67 and Increased Risk of Recurrent Disease in Localized Prostate Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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c-MET Expression Level in Primary Colon Cancer: A Predictor of Tumor Invasion and Lymph Node Metastases 1

Hiroya Takeuchi; Anton Bilchik; Sukamal Saha; Roderick Turner; David Wiese; Maki Tanaka; Christine Kuo; He-Jing Wang; Dave S. B. Hoon

Abstract

View articletitled, c-MET Expression Level in Primary Colon Cancer: A Predictor of Tumor Invasion and Lymph Node Metastases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Telomere Dynamics in Myelodysplastic Syndrome Determined by Telomere Measurement of Marrow Metaphases 1

Goro Sashida; Junko H. Ohyashiki; Akihiro Nakajima; Masahiko Sumi; Ken Kawakubo; Tetsuzo Tauchi; Kazuma Ohyashiki

Abstract

View articletitled, Telomere Dynamics in Myelodysplastic Syndrome Determined by Telomere Measurement of Marrow Metaphases<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Changes in the Presence of Multiple Markers of Circulating Melanoma Cells Correlate with Clinical Outcome in Patients with Melanoma 1

Sandra R. Reynolds; Jeff Albrecht; Richard L. Shapiro; Daniel F. Roses; Matthew N. Harris; Andrew Conrad; Anne Zeleniuch-Jacquotte; Jean-Claude Bystryn

Abstract

View articletitled, Changes in the Presence of Multiple Markers of Circulating Melanoma Cells Correlate with Clinical Outcome in Patients with Melanoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Clinical Significance of Aminopeptidase N/CD13 Expression in Human Pancreatic Carcinoma 1

Naoya Ikeda; Yoshiyuki Nakajima; Takahiro Tokuhara; Noboru Hattori; Masayuki Sho; Hiromichi Kanehiro; Masayuki Miyake

Abstract

View articletitled, Clinical Significance of Aminopeptidase N/CD13 Expression in Human Pancreatic Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Detection of Chromosomal Instability in Paired Breast Surgery and Ductal Lavage Specimens by Interphase Fluorescence in Situ Hybridization 1

Bonnie L. King; Steven C. Tsai; Michele E. Gryga; Thomas G. D’Aquila; Steven A. Seelig; Larry E. Morrison; Kris K. B. Jacobson; Mona S. Legator; David C. Ward; David L. Rimm; Rogsbert F. Phillips

Abstract

View articletitled, Detection of Chromosomal Instability in Paired Breast Surgery and Ductal Lavage Specimens by Interphase Fluorescence in Situ Hybridization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Experimental Therapeutics, Preclinical Pharmacology

TRANCE- and CD40 Ligand-matured Dendritic Cells Reveal MHC Class I-restricted T Cells Specific for Autologous Tumor in Late-Stage Ovarian Cancer Patients 1

Katia Schlienger; Christina S. Chu; Edward Y. Woo; Patricia M. Rivers; Alanna J. Toll; Brian Hudson; Marcela V. Maus; James L. Riley; Yongwon Choi; George Coukos; Larry R. Kaiser; Stephen C. Rubin; Bruce L. Levine; Richard G. Carroll; Carl H. June

Abstract

View articletitled, TRANCE- and CD40 Ligand-matured Dendritic Cells Reveal MHC Class I-restricted T Cells Specific for Autologous Tumor in Late-Stage Ovarian Cancer Patients<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Possible Role of Placental Leucine Aminopeptidase in the Antiproliferative Effect of Oxytocin in Human Endometrial Adenocarcinoma

Yuka Suzuki; Kiyosumi Shibata; Fumitaka Kikkawa; Hiroaki Kajiyama; Kazuhiko Ino; Seiji Nomura; Masafumi Tsujimoto; Shigehiko Mizutani

Abstract

View articletitled, Possible Role of Placental Leucine Aminopeptidase in the Antiproliferative Effect of Oxytocin in Human Endometrial Adenocarcinoma

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Antitumor Effects of ZD6474, a Small Molecule Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, with Additional Activity against Epidermal Growth Factor Receptor Tyrosine Kinase 1

Fortunato Ciardiello; Rosa Caputo; Vincenzo Damiano; Roberta Caputo; Teresa Troiani; Donatella Vitagliano; Francesca Carlomagno; Bianca Maria Veneziani; Gabriella Fontanini; A. Raffaele Bianco; Giampaolo Tortora

Abstract

View articletitled, Antitumor Effects of ZD6474, a Small Molecule Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, with Additional Activity against Epidermal Growth Factor Receptor Tyrosine Kinase<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Low-Dose Fractionated Radiation Potentiates the Effects of Paclitaxel in Wild-type and Mutant p53 Head and Neck Tumor Cell Lines

Swatee Dey; Paul M. Spring; Suzanne Arnold; Joseph Valentino; Damodaran Chendil; William F. Regine; Mohammed Mohiuddin; Mansoor M. Ahmed

Abstract

View articletitled, Low-Dose Fractionated Radiation Potentiates the Effects of Paclitaxel in Wild-type and Mutant p53 Head and Neck Tumor Cell Lines

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Combination of a Selective Cyclooxygenase-2 Inhibitor with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 and Protein Kinase A Antisense Causes Cooperative Antitumor and Antiangiogenic Effect 1

Giampaolo Tortora; Rosa Caputo; Vincenzo Damiano; Davide Melisi; Roberto Bianco; Gabriella Fontanini; Bianca Maria Veneziani; Sabino De Placido; A. Raffaele Bianco; Fortunato Ciardiello

Abstract

View articletitled, Combination of a Selective Cyclooxygenase-2 Inhibitor with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 and Protein Kinase A Antisense Causes Cooperative Antitumor and Antiangiogenic Effect<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Corrections

Correction for vol. 8, p. 3718

Extract

View articletitled, Correction for vol. 8, p. 3718

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Erratum

Correction for vol. 9, p. 295

Extract

View articletitled, Correction for vol. 9, p. 295

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