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Volume 9, Issue 14

1 November 2003

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Cover Image

Cover Image

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Review
Perspectives
The Biology Behind
Featured Articles
Regular Articles
- Clinical Trials
Research Articles
- Molecular Oncology, Markers, Clinical Correlates
- Experimental Therapeutics, Preclinical Pharmacology
Letters to the Editor

Review

Current Status of Gene Therapy for Lung Cancer and Head and Neck Cancer

Chulso Moon; Yun Oh; Jack A. Roth

Abstract

View articletitled, Current Status of Gene Therapy for Lung Cancer and Head and Neck Cancer

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Perspectives

The Importance of Pharmacokinetic Limited Sampling Models for Childhood Cancer Drug Development

J. Carl Panetta; Lisa C. Iacono; Peter C. Adamson; Clinton F. Stewart

Abstract

View articletitled, The Importance of Pharmacokinetic Limited Sampling Models for Childhood Cancer Drug Development

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HER-2-Targeted Therapy: Lessons Learned and Future Directions

Rita Nahta; Francisco J. Esteva

Abstract

View articletitled, HER-2-Targeted Therapy: Lessons Learned and Future Directions

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The Biology Behind

Suppression of Met Expression: A Possible Cancer Treatment : Commentary re: S. J. Kim et al., Reduced c-Met Expression by an Adenovirus Expressing a c-Met Ribozyme Inhibits Tumorigenic Growth and Lymph Node Metastases of PC3-LN4 Prostate Tumor Cells in an Orthotopic Nude Mouse Model. Clin. Cancer Res., 14: 5161-5170, 2003.

Nariyoshi Shinomiya; George F. Vande Woude

Extract

View articletitled, Suppression of Met Expression: A Possible Cancer Treatment : Commentary re: S. J. Kim et al., Reduced c-Met Expression by an Adenovirus Expressing a c-Met Ribozyme Inhibits Tumorigenic Growth and Lymph Node Metastases of PC3-LN4 Prostate Tumor Cells in an Orthotopic Nude Mouse Model. Clin. Cancer Res., 14: 5161-5170, 2003.

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Featured Articles

Clinical Trials

Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients

I. Jolanda M. de Vries; W. Joost Lesterhuis; Nicole M. Scharenborg; Linda P. H. Engelen; Dirk J. Ruiter; Marie-Jeanne P. Gerritsen; Sandra Croockewit; Cedrik M. Britten; Ruurd Torensma; Gosse J. Adema; Carl G. Figdor; Cornelis J. A. Punt

Abstract

View articletitled, Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients

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A Phase I Study of SR-4554 via Intravenous Administration for Noninvasive Investigation of Tumor Hypoxia by Magnetic Resonance Spectroscopy in Patients with Malignancy

Beatrice M. Seddon; Geoffrey S. Payne; Laura Simmons; Ruth Ruddle; Rachel Grimshaw; Siew Tan; Alison Turner; Florence Raynaud; Gavin Halbert; Martin O. Leach; Ian Judson; Paul Workman

Abstract

View articletitled, A Phase I Study of SR-4554 via Intravenous Administration for Noninvasive Investigation of Tumor Hypoxia by Magnetic Resonance Spectroscopy in Patients with Malignancy

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Molecular Oncology, Markers, Clinical Correlates

T-Cell Apoptosis and Suppression of T-Cell Receptor/CD3-ζ by Fas Ligand-Containing Membrane Vesicles Shed from Ovarian Tumors

Douglas D. Taylor; Çiçek Gerçel-Taylor; Karen S. Lyons; Joanna Stanson; Theresa L. Whiteside

Abstract

View articletitled, T-Cell Apoptosis and Suppression of T-Cell Receptor/CD3-ζ by Fas Ligand-Containing Membrane Vesicles Shed from Ovarian Tumors

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Recursive Partitioning as an Approach to Selection of Immune Markers for Tumor Diagnosis

James A. Koziol; Jian-Ying Zhang; Carlos A. Casiano; Xuan-Xian Peng; Fu-Dong Shi; Anne C. Feng; Edward K. L. Chan; Eng M. Tan

Abstract

View articletitled, Recursive Partitioning as an Approach to Selection of Immune Markers for Tumor Diagnosis

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Reverse Transcription-PCR Analysis of Laser-Captured Cells Points to Potential Paracrine and Autocrine Actions of Neurotrophins in Pancreatic Cancer

Knut Ketterer; Shyam Rao; Helmut Friess; John Weiss; Markus W. Büchler; Murray Korc

Abstract

View articletitled, Reverse Transcription-PCR Analysis of Laser-Captured Cells Points to Potential Paracrine and Autocrine Actions of Neurotrophins in Pancreatic Cancer

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Prediction of Nodal Metastasis by Comparative Genomic Hybridization in Biopsy Specimens from Patients with Superficial Esophageal Squamous Cell Carcinoma

Takashi Ueno; Akira Tangoku; Shigefumi Yoshino; Toshihiro Abe; Hideto Hayashi; Hiroaki Toshimitsu; Kiichiro Hashimoto; Tomomitsu Satoh; Atsunori Oga; Tomoko Furuya; Masaaki Oka; Kohsuke Sasaki

Abstract

View articletitled, Prediction of Nodal Metastasis by Comparative Genomic Hybridization in Biopsy Specimens from Patients with Superficial Esophageal Squamous Cell Carcinoma

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Endometriosis and Its Treatment with Danazol or Lupron in Relation to Ovarian Cancer

Carrie M. Cottreau; Roberta B. Ness; Francesmary Modugno; Glenn O. Allen; Marc T. Goodman

Abstract

View articletitled, Endometriosis and Its Treatment with Danazol or Lupron in Relation to Ovarian Cancer

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Real-Time Quantification of CK-19 mRNA-Positive Cells in Peripheral Blood of Breast Cancer Patients Using the Lightcycler System

Aliki Stathopoulou; Anna Gizi; Maria Perraki; Stella Apostolaki; Nikos Malamos; Dimitris Mavroudis; Vassilis Georgoulias; Evi S. Lianidou

Abstract

View articletitled, Real-Time Quantification of CK-19 mRNA-Positive Cells in Peripheral Blood of Breast Cancer Patients Using the Lightcycler System

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Experimental Therapeutics, Preclinical Pharmacology

Introduction of Midkine Gene into Human Bladder Cancer Cells Enhances Their Malignant Phenotype But Increases Their Sensitivity to Antiangiogenic Therapy

Mototsugu Muramaki; Hideaki Miyake; Isao Hara; Sadao Kamidono

Abstract

View articletitled, Introduction of Midkine Gene into Human Bladder Cancer Cells Enhances Their Malignant Phenotype But Increases Their Sensitivity to Antiangiogenic Therapy

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Reduced c-Met Expression by an Adenovirus Expressing a c-Met Ribozyme Inhibits Tumorigenic Growth and Lymph Node Metastases of PC3-LN4 Prostate Tumor Cells in an Orthotopic Nude Mouse Model

Sun Jin Kim; Marjorie Johnson; Kristen Koterba; Matthew H. Herynk; Hisanori Uehara; Gary E. Gallick

Abstract

View articletitled, Reduced c-Met Expression by an Adenovirus Expressing a c-Met Ribozyme Inhibits Tumorigenic Growth and Lymph Node Metastases of PC3-LN4 Prostate Tumor Cells in an Orthotopic Nude Mouse Model

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The Role of Breast Cancer Resistance Protein in Acute Lymphoblastic Leukemia

Sabine L. A. Plasschaert; Dorina M. van der Kolk; Eveline S. J. M. de Bont; Willem A. Kamps; Kuniaki Morisaki; Susan E. Bates; George L. Scheffer; Rik J. Scheper; Edo Vellenga; Elisabeth G. E. de Vries

Abstract

View articletitled, The Role of Breast Cancer Resistance Protein in Acute Lymphoblastic Leukemia

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Regular Articles

Clinical Trials

Phase I Clinical Trial and Pharmacokinetic Study of the Spicamycin Analog KRN5500 Administered as a 1-Hour Intravenous Infusion for Five Consecutive Days to Patients with Refractory Solid Tumors

Jeffrey G. Supko; Joseph P. Eder, Jr.; David P. Ryan; Michael V. Seiden; Thomas J. Lynch; Phillip C. Amrein; Donald W. Kufe; Jeffrey W. Clark

Abstract

View articletitled, Phase I Clinical Trial and Pharmacokinetic Study of the Spicamycin Analog KRN5500 Administered as a 1-Hour Intravenous Infusion for Five Consecutive Days to Patients with Refractory Solid Tumors

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Phase I and Pharmacokinetic Study of BMS-188797, a New Taxane Analog, Administered on a Weekly Schedule in Patients with Advanced Malignancies

Ranjana Advani; George A. Fisher; Bert L. Lum; Charro Jambalos; Cheryl D. Cho; Marvin Cohen; Ashwin Gollerkeri; Branimir I. Sikic

Abstract

View articletitled, Phase I and Pharmacokinetic Study of BMS-188797, a New Taxane Analog, Administered on a Weekly Schedule in Patients with Advanced Malignancies

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Phase I and Pharmacokinetic Study of E7070, a Chloroindolyl-Sulfonamide Anticancer Agent, Administered on a Weekly Schedule to Patients with Solid Tumors

Christian Dittrich; Herlinde Dumez; Hilary Calvert; Axel Hanauske; Marije Faber; Jantien Wanders; Murray Yule; Miroslav Ravic; Pierre Fumoleau

Abstract

View articletitled, Phase I and Pharmacokinetic Study of E7070, a Chloroindolyl-Sulfonamide Anticancer Agent, Administered on a Weekly Schedule to Patients with Solid Tumors

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Vaccinia-Expressed Human Papillomavirus 16 and 18 E6 and E7 as a Therapeutic Vaccination for Vulval and Vaginal Intraepithelial Neoplasia

Peter J. Baldwin; Sjoerd H. van der Burg; Christopher M. Boswell; Rienk Offringa; Julian K. Hickling; Jennifer Dobson; John St. Clair Roberts; John A. Latimer; Robin P. Moseley; Nicholas Coleman; Margaret A. Stanley; Jane C. Sterling

Abstract

View articletitled, Vaccinia-Expressed Human Papillomavirus 16 and 18 E6 and E7 as a Therapeutic Vaccination for Vulval and Vaginal Intraepithelial Neoplasia

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Consistent Antibody Response against Ganglioside GD2 Induced in Patients with Melanoma by a GD2 Lactone-Keyhole Limpet Hemocyanin Conjugate Vaccine plus Immunological Adjuvant QS-21

Govind Ragupathi; Philip O. Livingston; Chandra Hood; John Gathuru; Susan E. Krown; Paul B. Chapman; Jedd D. Wolchok; Linda J. Williams; Roberta C. Oldfield; Wen-Jen Hwu

Abstract

View articletitled, Consistent Antibody Response against Ganglioside GD2 Induced in Patients with Melanoma by a GD2 Lactone-Keyhole Limpet Hemocyanin Conjugate Vaccine plus Immunological Adjuvant QS-21

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Phase I and Pharmacokinetic Trial of the Novel Taxane BMS-184476 Administered as a 1-Hour Intravenous Infusion in Combination with Cisplatin Every 21 Days

Weijing Sun; James P. Stevenson; Maryann L. Gallagher; David Vaughn; Steven M. Hahn; Daniel G. Haller; Marvin Cohen; Justin Kopit; Gilles Gallant; Peter J. O’Dwyer

Abstract

View articletitled, Phase I and Pharmacokinetic Trial of the Novel Taxane BMS-184476 Administered as a 1-Hour Intravenous Infusion in Combination with Cisplatin Every 21 Days

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Pilot Study of Flt3 Ligand Comparing Intraperitoneal with Subcutaneous Routes on Hematologic and Immunologic Responses in Patients with Peritoneal Carcinomatosis and Mesotheliomas

Ralph S. Freedman; Saroj Vadhan-Raj; Cherie Butts; Cherylyn Savary; Bohuslav Melichar; Claire Verschraegen; John J. Kavanagh; Marshall E. Hicks; Lawrence B. Levy; Jody K. Folloder; Michael E. Garcia

Abstract

View articletitled, Pilot Study of Flt3 Ligand Comparing Intraperitoneal with Subcutaneous Routes on Hematologic and Immunologic Responses in Patients with Peritoneal Carcinomatosis and Mesotheliomas

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Research Articles

Molecular Oncology, Markers, Clinical Correlates

HER2 Status in Non-Small Cell Lung Cancer: Results from Patient Screening for Enrollment to a Phase II Study of Herceptin

Petra Heinmöller; Christof Gross; Kurt Beyser; Claudia Schmidtgen; Gerd Maass; Michele Pedrocchi; Josef Rüschoff

Abstract

View articletitled, HER2 Status in Non-Small Cell Lung Cancer: Results from Patient Screening for Enrollment to a Phase II Study of Herceptin

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Higher Gastric Cycloxygenase-2 Expression and Precancerous Change in Helicobacter pylori-Infected Relatives of Gastric Cancer Patients

Bor-Shyang Sheu; Hsiao-Bai Yang; Shew-Meei Sheu; Ay-Huey Huang; Jiunn-Jong Wu

Abstract

View articletitled, Higher Gastric Cycloxygenase-2 Expression and Precancerous Change in Helicobacter pylori-Infected Relatives of Gastric Cancer Patients

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Germ-Line Alterations in MSR1 Gene and Prostate Cancer Risk

Eija H. Seppälä; Tarja Ikonen; Ville Autio; Annika Rökman; Nina Mononen; Mika P. Matikainen; Teuvo L. J. Tammela; Johanna Schleutker

Abstract

View articletitled, Germ-Line Alterations in MSR1 Gene and Prostate Cancer Risk

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Hypermethylation-Associated Inactivation of Retinoic Acid Receptor β in Human Esophageal Squamous Cell Carcinoma

Yimin Wang; Ming Zhu Fang; Jie Liao; Guang-Yu Yang; Yan Nie; Yunlong Song; Chi So; Xiaochun Xu; Li-Dong Wang; Chung S. Yang

Abstract

View articletitled, Hypermethylation-Associated Inactivation of Retinoic Acid Receptor β in Human Esophageal Squamous Cell Carcinoma

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Interferon Can Block Telomere Erosion and in Rare Cases Result in Hepatocellular Carcinoma Development with Telomeric Repeat Binding Factor 1 Overexpression in Chronic Hepatitis C

Masato Igarashi; Takeshi Suda; Hidenori Hara; Mitsuhiro Takimoto; Minoru Nomoto; Toru Takahashi; Shogo Okoshi; Hirokazu Kawai; Yusaku Mita; Nobuo Waguri; Yutaka Aoyagi

Abstract

View articletitled, Interferon Can Block Telomere Erosion and in Rare Cases Result in Hepatocellular Carcinoma Development with Telomeric Repeat Binding Factor 1 Overexpression in Chronic Hepatitis C

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Gene Amplifications Associated with the Development of Hormone-Resistant Prostate Cancer

Joanne Edwards; N. Sarath Krishna; Caroline J. Witton; John M. S. Bartlett

Abstract

View articletitled, Gene Amplifications Associated with the Development of Hormone-Resistant Prostate Cancer

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Higher Expression of RhoC Is Related to Invasiveness in Non-Small Cell Lung Carcinoma

Yasunori Shikada; Ichiro Yoshino; Tatsuro Okamoto; Seiichi Fukuyama; Toshifumi Kameyama; Yoshihiko Maehara

Abstract

View articletitled, Higher Expression of RhoC Is Related to Invasiveness in Non-Small Cell Lung Carcinoma

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Detection of Rare Disseminated Tumor Cells Identifies Head and Neck Cancer Patients at Risk of Treatment Failure

Max Partridge; Ruud Brakenhoff; Elaine Phillips; Kulsan Ali; Rebecca Francis; Richard Hooper; Kenneth Lavery; Andrew Brown; John Langdon

Abstract

View articletitled, Detection of Rare Disseminated Tumor Cells Identifies Head and Neck Cancer Patients at Risk of Treatment Failure

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Methylation-Mediated Silencing of SOCS-1 Gene in Hepatocellular Carcinoma Derived from Cirrhosis

Osamu Okochi; Kenji Hibi; Mitsuru Sakai; Soichiro Inoue; Shin Takeda; Tetsuya Kaneko; Akimasa Nakao

Abstract

View articletitled, Methylation-Mediated Silencing of SOCS-1 Gene in Hepatocellular Carcinoma Derived from Cirrhosis

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Clear Cell Tumors Have Higher mRNA Levels of ERCC1 and XPB Than Other Histological Types of Epithelial Ovarian Cancer

Eddie Reed; Jing Jie Yu; Antony Davies; James Gannon; Steven L. Armentrout

Abstract

View articletitled, Clear Cell Tumors Have Higher mRNA Levels of ERCC1 and XPB Than Other Histological Types of Epithelial Ovarian Cancer

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Hypermethylation of O⁶-Methylguanine-DNA Methyltransferase Promoter May Predict Nonrecurrence after Chemotherapy in Colorectal Cancer Cases

Takeshi Nagasaka; Gerald B. Sharp; Kenji Notohara; Takeshi Kambara; Hiromi Sasamoto; Hiroshi Isozaki; Donald G. MacPhee; Jeremy R. Jass; Noriaki Tanaka; Nagahide Matsubara

Abstract

View articletitled, Hypermethylation of O6-Methylguanine-DNA Methyltransferase Promoter May Predict Nonrecurrence after Chemotherapy in Colorectal Cancer Cases

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Flt-4-Positive Vessel Density Correlates with Vascular Endothelial Growth Factor-D Expression, Nodal Status, and Prognosis in Breast Cancer

Yasushi Nakamura; Hironao Yasuoka; Masahiko Tsujimoto; Qifeng Yang; Shigeru Imabun; Masaaki Nakahara; Kazuyasu Nakao; Misa Nakamura; Ichiro Mori; Kennichi Kakudo

Abstract

View articletitled, Flt-4-Positive Vessel Density Correlates with Vascular Endothelial Growth Factor-D Expression, Nodal Status, and Prognosis in Breast Cancer

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CD44 Expression Indicates Favorable Prognosis in Epithelial Ovarian Cancer

Sari Sillanpää; Maarit A. Anttila; Kirsi Voutilainen; Raija H. Tammi; Markku I. Tammi; Seppo V. Saarikoski; Veli-Matti Kosma

Abstract

View articletitled, CD44 Expression Indicates Favorable Prognosis in Epithelial Ovarian Cancer

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Expression of Activated Extracellular Signal-Regulated Kinases 1/2 in Malignant Melanomas: Relationship with Clinical Outcome

Kjersti Jørgensen; Ruth Holm; Gunhild M. Mælandsmo; Vivi Ann Flørenes

Abstract

View articletitled, Expression of Activated Extracellular Signal-Regulated Kinases 1/2 in Malignant Melanomas: Relationship with Clinical Outcome

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Frequent Loss of Expression of the Cyclin-Dependent Kinase Inhibitor p27^Kip1 in Estrogen-Related Endometrial Adenocarcinomas

Valeria Masciullo; Tommaso Susini; Alessandra Zamparelli; Alessandro Bovicelli; Corrado Minimo; Daniela Massi; Gianluigi Taddei; Nicola Maggiano; Pierandrea De Iaco; Marcello Ceccaroni; Luciano Bovicelli; Gianni Amunni; Salvatore Mancuso; Giovanni Scambia; Antonio Giordano

Abstract

View articletitled, Frequent Loss of Expression of the Cyclin-Dependent Kinase Inhibitor p27Kip1 in Estrogen-Related Endometrial Adenocarcinomas

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Tissue Factor Expression Correlates with Tumor Angiogenesis and Invasiveness in Human Hepatocellular Carcinoma

Ronnie Tung-Ping Poon; Cecilia Pik-Yuk Lau; Joanna Wen-Ying Ho; Wan-Ching Yu; Sheung-Tat Fan; John Wong

Abstract

View articletitled, Tissue Factor Expression Correlates with Tumor Angiogenesis and Invasiveness in Human Hepatocellular Carcinoma

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Identification of Patients with Transitional Cell Carcinoma of the Bladder Overexpressing ErbB2, ErbB3, or Specific ErbB4 Isoforms: Real-Time Reverse Transcription-PCR Analysis in Estimation of ErbB Receptor Status from Cancer Patients

Teemu T. Junttila; Matti Laato; Tero Vahlberg; Karl-Ove Söderström; Tapio Visakorpi; Jorma Isola; Klaus Elenius

Abstract

View articletitled, Identification of Patients with Transitional Cell Carcinoma of the Bladder Overexpressing ErbB2, ErbB3, or Specific ErbB4 Isoforms: Real-Time Reverse Transcription-PCR Analysis in Estimation of ErbB Receptor Status from Cancer Patients

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Experimental Therapeutics, Preclinical Pharmacology

Angiosuppressive and Angiostimulatory Effects Exerted by Synthetic Partial Sequences of Endostatin

Lucia Morbidelli; Sandra Donnini; Francesco Chillemi; Antonio Giachetti; Marina Ziche

Abstract

View articletitled, Angiosuppressive and Angiostimulatory Effects Exerted by Synthetic Partial Sequences of Endostatin

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Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymphoma

Lucio Tentori; Carlo Leonetti; Marco Scarsella; Giulia d’Amati; Matteo Vergati; Ilaria Portarena; Weizheng Xu; Vincent Kalish; Gabriella Zupi; Jie Zhang; Grazia Graziani

Abstract

View articletitled, Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymphoma

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Combined Therapy with a New Bisphosphonate, Minodronate (YM529), and Chemotherapy for Multiple Organ Metastases of Small Cell Lung Cancer Cells in Severe Combined Immunodeficient Mice

Seiji Yano; Helong Zhang; Masaki Hanibuchi; Toyokazu Miki; Hisatsugu Goto; Hisanori Uehara; Saburo Sone

Abstract

View articletitled, Combined Therapy with a New Bisphosphonate, Minodronate (YM529), and Chemotherapy for Multiple Organ Metastases of Small Cell Lung Cancer Cells in Severe Combined Immunodeficient Mice

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Identification of Naturally Processed Helper T-Cell Epitopes from Prostate-Specific Membrane Antigen Using Peptide-Based in Vitro Stimulation

Hiroya Kobayashi; Ryusuke Omiya; Benjamin Sodey; Mitsuru Yanai; Kensuke Oikawa; Keisuke Sato; Shoji Kimura; Satoru Senju; Yasuharu Nishimura; Masatoshi Tateno; Esteban Celis

Abstract

View articletitled, Identification of Naturally Processed Helper T-Cell Epitopes from Prostate-Specific Membrane Antigen Using Peptide-Based in Vitro Stimulation

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The Histone Deacetylase Inhibitor FK228 Preferentially Enhances Adenovirus Transgene Expression in Malignant Cells

Merrill E. Goldsmith; Masaki Kitazono; Patrick Fok; Takashi Aikou; Susan Bates; Tito Fojo

Abstract

View articletitled, The Histone Deacetylase Inhibitor FK228 Preferentially Enhances Adenovirus Transgene Expression in Malignant Cells

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Enhancement of in Vivo Antitumor Activity of Classical Anticancer Agents by Combination with the New, Glutathione-Interacting DNA Minor Groove-Binder, Brostallicin

Maria Antonietta Sabatino; Tina Colombo; Cristina Geroni; Sergio Marchini; Massimo Broggini

Abstract

View articletitled, Enhancement of in Vivo Antitumor Activity of Classical Anticancer Agents by Combination with the New, Glutathione-Interacting DNA Minor Groove-Binder, Brostallicin

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Cyclosporin-A Enhances Docetaxel-Induced Apoptosis through Inhibition of Nuclear Factor-κB Activation in Human Gastric Carcinoma Cells

Chihiro Nakahara; Katsuya Nakamura; Naoki Yamanaka; Eishi Baba; Morimasa Wada; Hisashi Matsunaga; Hirokazu Noshiro; Masao Tanaka; Takashi Morisaki; Mitsuo Katano

Abstract

View articletitled, Cyclosporin-A Enhances Docetaxel-Induced Apoptosis through Inhibition of Nuclear Factor-κB Activation in Human Gastric Carcinoma Cells

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Inhibition of Cyclooxygenase-2 Indirectly Potentiates Antitumor Effects of Photodynamic Therapy in Mice

Marcin Makowski; Tomasz Grzela; Justyna Niderla; Maciej Łazarczyk; Paweł Mróz; Maciej Kopeé; Magdalena Legat; Katarzyna Strusińska; Katarzyna Koziak; Dominika Nowis; Piotr Mrówka; Maria Wąsik; Marek Jakóbisiak; Jakub Gołąb

Abstract

View articletitled, Inhibition of Cyclooxygenase-2 Indirectly Potentiates Antitumor Effects of Photodynamic Therapy in Mice

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Peptides Inhibitory for the Transcriptional Regulatory Function of Human Papillomavirus E2

Takuma Fujii; David Austin; David Guo; Srinivasan Srimatkandada; Tao Wang; Kaneyuki Kubushiro; Nobuo Masumoto; Katsumi Tsukazaki; Shiro Nozawa; Albert B. Deisseroth

Abstract

View articletitled, Peptides Inhibitory for the Transcriptional Regulatory Function of Human Papillomavirus E2

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Letters to the Editor

Correspondence re: J. Lu et al., Thalidomide Metabolites in Mice and Patients with Multiple Myeloma. Clin. Cancer Res., 9: 1680–1688, 2003.

Shufeng Zhou

Extract

View articletitled, Correspondence re: J. Lu et al., Thalidomide Metabolites in Mice and Patients with Multiple Myeloma. Clin. Cancer Res., 9: 1680–1688, 2003.

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Correspondence re: J. Lu et al., Thalidomide Metabolites in Mice and Patients with Multiple Myeloma. Clin. Cancer Res., 9: 1680–1688, 2003.

Extract

View articletitled, Correspondence re: J. Lu et al., Thalidomide Metabolites in Mice and Patients with Multiple Myeloma. Clin. Cancer Res., 9: 1680–1688, 2003.

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Correspondence re: M. Provencio, et al. The Topoisomerase IIa Expression Correlates with Survival in Patients with Advanced Hodgkin’s Lymphoma. Clin. Cancer Res., 9: 1406–1411, 2003.

Theodoros P. Vassilakopoulos; Maria K. Angelopoulou; Marina P. Siakantaris; Gerassimos A. Pangalis; Christos Kittas; Ipatia Doussis-Anagnostopoulou

Extract

View articletitled, Correspondence re: M. Provencio, et al. The Topoisomerase IIa Expression Correlates with Survival in Patients with Advanced Hodgkin’s Lymphoma. Clin. Cancer Res., 9: 1406–1411, 2003.

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Issues

Cover Image

Review

Perspectives

The Biology Behind

Featured Articles

Clinical Trials

Molecular Oncology, Markers, Clinical Correlates

Experimental Therapeutics, Preclinical Pharmacology

Regular Articles

Clinical Trials

Research Articles

Molecular Oncology, Markers, Clinical Correlates

Experimental Therapeutics, Preclinical Pharmacology

Letters to the Editor

Email alerts

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