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Editorial

Protein Kinase A Type I: A Target For Cancer Therapy

View articletitled, Protein Kinase A Type I: A Target For Cancer Therapy

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The Biology Behind

Cancer Prevention by Delay 1: Commentary re: J. A. O’Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314–346, 2002.

Scott M. Lippman; Waun Ki Hong

Extract

View articletitled, Cancer Prevention by Delay<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>: Commentary re: J. A. O’Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314–346, 2002.

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Special Article

Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development : Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia 1

Abstract

View articletitled, Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development : Recommendations of the American Association for Cancer Research Task Force on the Treatment and Prevention of Intraepithelial Neoplasia<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Advances in Brief

Molecular Oncology, Markers, Clinical Correlates

NH₂-terminal Truncated HER-2 Protein but not Full-Length Receptor Is Associated with Nodal Metastasis in Human Breast Cancer 1

Miguel A. Molina; Rosana Sáez; Elizabeth E. Ramsey; María-José Garcia-Barchino; Federico Rojo; Adam J. Evans; Joan Albanell; Edward J. Keenan; Ana Lluch; Javier García-Conde; José Baselga; Gail M. Clinton

Abstract

View articletitled, NH2-terminal Truncated HER-2 Protein but not Full-Length Receptor Is Associated with Nodal Metastasis in Human Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Experimental Therapeutics, Preclinical Pharmacology

Sulindac Enhances Tumor Necrosis Factor-α-mediated Apoptosis of Lung Cancer Cell Lines by Inhibition of Nuclear Factor-κB 1

Kevin S. Berman; Udit N. Verma; Gwyndolen Harburg; John D. Minna; Melanie H. Cobb; Richard B. Gaynor

Abstract

View articletitled, Sulindac Enhances Tumor Necrosis Factor-α-mediated Apoptosis of Lung Cancer Cell Lines by Inhibition of Nuclear Factor-κB<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression Profile of Tyrosine Kinases in Breast Cancer 1

Funda Meric; Wei-Ping Lee; Aysegul Sahin; Haixia Zhang; Hsing-Jien Kung; Mien-Chie Hung

Abstract

View articletitled, Expression Profile of Tyrosine Kinases in Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regular Articles

Clinical Trials

Evidence of Determinant Spreading in the Antibody Responses to Prostate Cell Surface Antigens in Patients Immunized with Prostate-specific Antigen 1

Lisa A. Cavacini; Mark Duval; J. Paul Eder; Marshall R. Posner

Abstract

View articletitled, Evidence of Determinant Spreading in the Antibody Responses to Prostate Cell Surface Antigens in Patients Immunized with Prostate-specific Antigen<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Liposomal Doxorubicin in Conjunction with Reirradiation and Local Hyperthermia Treatment in Recurrent Breast Cancer: A Phase I/II Trial

Vassilios E. Kouloulias; Costas E. Dardoufas; John R. Kouvaris; Costas S. Gennatas; Aris K. Polyzos; Helen J. Gogas; Panagiotis H. Sandilos; Nikolaos K. Uzunoglu; Elias G. Malas; Lambros J. Vlahos

Abstract

View articletitled, Liposomal Doxorubicin in Conjunction with Reirradiation and Local Hyperthermia Treatment in Recurrent Breast Cancer: A Phase I/II Trial

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Safety and Efficacy of the Multidrug-Resistance Inhibitor Biricodar (VX-710) with Concurrent Doxorubicin in Patients with Anthracycline-resistant Advanced Soft Tissue Sarcoma 1

Vivien H. C. Bramwell; Donald Morris; D. Scott Ernst; Ingrid Hings; Martin Blackstein; Peter M. Venner; Ene I. Ette; Matthew W. Harding; Allison Waxman; George D. Demetri

Abstract

View articletitled, Safety and Efficacy of the Multidrug-Resistance Inhibitor Biricodar (VX-710) with Concurrent Doxorubicin in Patients with Anthracycline-resistant Advanced Soft Tissue Sarcoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Individual Adaptive Dosing of Topotecan in Ovarian Cancer 1

Ashraf Montazeri; Stéphane Culine; Brigitte Laguerre; Frédéric Pinguet; François Lokiec; Nicolas Albin; Alain Goupil; Régine Déporte-Féty; Roland Bugat; Pierre Canal; Etienne Chatelut

Abstract

View articletitled, Individual Adaptive Dosing of Topotecan in Ovarian Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Picking the Winners in a Sea of Plenty 1

Howard I. Scher; Glenn Heller

Abstract

View articletitled, Picking the Winners in a Sea of Plenty<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Continuous Administration of Irinotecan by Hepatic Arterial Infusion: A Phase I and Pharmacokinetic Study

Johanna M. G. H. van Riel; Cees J. van Groeningen; Mark A. Kedde; Helen Gall; Johanna M. A. Leisink; Gabriella Gruia; Herbert M. Pinedo; Wim J. F. van der Vijgh; Giuseppe Giaccone

Abstract

View articletitled, Continuous Administration of Irinotecan by Hepatic Arterial Infusion: A Phase I and Pharmacokinetic Study

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Dose Escalation and Pharmacokinetics of Pegylated Liposomal Doxorubicin (Doxil) in Children with Solid Tumors: A Pediatric Oncology Group Study 1

Neyssa M. Marina; Debon Cochrane; Elaine Harney; Katie Zomorodi; Susan Blaney; Naomi Winick; Mark Bernstein; Michael P. Link

Abstract

View articletitled, Dose Escalation and Pharmacokinetics of Pegylated Liposomal Doxorubicin (Doxil) in Children with Solid Tumors: A Pediatric Oncology Group Study<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Cell Biology

Automated Electrorotation to Reveal Dielectric Variations Related to HER-2/neu Overexpression in MCF-7 Sublines 1

Massimo Cristofanilli; Giovanni De Gasperis; Lisha Zhang; Mien-Chie Hung; Peter R. C. Gascoyne; Gabriel N. Hortobagyi

Abstract

View articletitled, Automated Electrorotation to Reveal Dielectric Variations Related to HER-2/neu Overexpression in MCF-7 Sublines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Modulation of the c-Met/Hepatocyte Growth Factor Pathway in Small Cell Lung Cancer 1

Gautam Maulik; Takashi Kijima; Patrick C. Ma; Sudip K. Ghosh; Jeffrey Lin; Geoffrey I. Shapiro; Erik Schaefer; Elena Tibaldi; Bruce E. Johnson; Ravi Salgia

Abstract

View articletitled, Modulation of the c-Met/Hepatocyte Growth Factor Pathway in Small Cell Lung Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Research Articles

Molecular Oncology, Markers, Clinical Correlates

Quantitative Evaluation of Somatostatin Receptor Subtype 2 Expression in Sporadic Colorectal Tumor and in the Corresponding Normal Mucosa 1

Claudia Casini Raggi; Antonino Calabrò; Daniela Renzi; Vittorio Briganti; Fabio Cianchi; Luca Messerini; Rosa Valanzano; Michela Cameron Smith; Camillo Cortesini; Francesco Tonelli; Mario Serio; Mario Maggi; Claudio Orlando

Abstract

View articletitled, Quantitative Evaluation of Somatostatin Receptor Subtype 2 Expression in Sporadic Colorectal Tumor and in the Corresponding Normal Mucosa<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Breast Epithelium Procurement from Stereotactic Core Biopsy Washings: Flow Cytometry-sorted Cell Count Analysis 1

Daniel L. Stoler; Carleton C. Stewart; Paul C. Stomper

Abstract

View articletitled, Breast Epithelium Procurement from Stereotactic Core Biopsy Washings: Flow Cytometry-sorted Cell Count Analysis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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High Frequency of Promoter Hypermethylation of the Death-associated Protein-Kinase Gene in Nasopharyngeal Carcinoma and Its Detection in the Peripheral Blood of Patients 1

Thian Sze Wong; Hsiao Wen Chang; Kwong Chi Tang; William Ignace Wei; Dora Lai Wen Kwong; Jonathan Shun Tong Sham; Anthony Po Wing Yuen; Yok Lam Kwong

Abstract

View articletitled, High Frequency of Promoter Hypermethylation of the Death-associated Protein-Kinase Gene in Nasopharyngeal Carcinoma and Its Detection in the Peripheral Blood of Patients<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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The Role of Retinoid X Receptor Messenger RNA Expression in Curatively Resected Non-Small Cell Lung Cancer 1

Jan Brabender; Kathleen D. Danenberg; Ralf Metzger; Paul M. Schneider; Reginald V. Lord; Susan Groshen; Denice D. Tsao-Wei; JiMin Park; Dennis Salonga; Arnulf H. Hölscher; Peter V. Danenberg

Abstract

View articletitled, The Role of Retinoid X Receptor Messenger RNA Expression in Curatively Resected Non-Small Cell Lung Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Immunomagnetic Detection of Micrometastatic Cells in Bone Marrow of Colorectal Cancer Patients 1

Kjersti Flatmark; Kristin Bjørnland; Hans Olaf Johannessen; Elisabeth Hegstad; Rocio Rosales; Lisbeth Hårklau; Jan Helge Solhaug; Ragnar S. Faye; Odd Søreide; Øystein Fodstad; on behalf of the Study Group

Abstract

View articletitled, Immunomagnetic Detection of Micrometastatic Cells in Bone Marrow of Colorectal Cancer Patients<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression and Prognostic Roles of β-Catenin in Hepatocellular Carcinoma: Correlation with Tumor Progression and Postoperative Survival

Satoshi Inagawa; Masayuki Itabashi; Shinya Adachi; Toru Kawamoto; Masao Hori; Jiro Shimazaki; Fuyo Yoshimi; Katashi Fukao

Abstract

View articletitled, Expression and Prognostic Roles of β-Catenin in Hepatocellular Carcinoma: Correlation with Tumor Progression and Postoperative Survival

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RET Oligonucleotide Microarray for the Detection of RET Mutations in Multiple Endocrine Neoplasia Type 2 Syndromes 1

Il-Jin Kim; Hio Chung Kang; Jae-Hyun Park; Ja-Lok Ku; Jong-Soo Lee; Hyuk-Joon Kwon; Kyong-Ah Yoon; Seung Chul Heo; Hee-Young Yang; Bo Youn Cho; Seong Yeon Kim; Seung Keun Oh; Yeo-Kyu Youn; Do-Jun Park; Myung-Shik Lee; Kwang-Woo Lee; Jae-Gahb Park

Abstract

View articletitled, RET Oligonucleotide Microarray for the Detection of RET Mutations in Multiple Endocrine Neoplasia Type 2 Syndromes<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Hypermethylation of Multiple Genes in Tumor Tissues and Voided Urine in Urinary Bladder Cancer Patients

Michael W. Y. Chan; Lun W. Chan; Nelson L. S. Tang; Joanna H. M. Tong; Kwok W. Lo; Tin L. Lee; Ho Y. Cheung; Wai S. Wong; Peter S. F. Chan; Fernand M. M. Lai; Ka F. To

Abstract

View articletitled, Hypermethylation of Multiple Genes in Tumor Tissues and Voided Urine in Urinary Bladder Cancer Patients

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Hypoxia-induced, Perinecrotic Expression of Endothelial Per–ARNT–Sim Domain Protein-1/Hypoxia-inducible Factor-2α Correlates with Tumor Progression, Vascularization, and Focal Macrophage Infiltration in Bladder Cancer 1

Toru Onita; Ping Guang Ji; Jim W. Xuan; Hideki Sakai; Hiroshi Kanetake; Patrick H. Maxwell; Guo-Hua Fong; Manal Y Gabril; Madeleine Moussa; Joseph L. Chin

Abstract

View articletitled, Hypoxia-induced, Perinecrotic Expression of Endothelial Per–ARNT–Sim Domain Protein-1/Hypoxia-inducible Factor-2α Correlates with Tumor Progression, Vascularization, and Focal Macrophage Infiltration in Bladder Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Mitochondrial D-loop Mutations As Clonal Markers in Multicentric Hepatocellular Carcinoma and Plasma 1

Shuji Nomoto; Katsuya Yamashita; Katsumi Koshikawa; Akimasa Nakao; David Sidransky

Abstract

View articletitled, Mitochondrial D-loop Mutations As Clonal Markers in Multicentric Hepatocellular Carcinoma and Plasma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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BAX Expression in Hodgkin and Reed-Sternberg Cells of Hodgkin’s Disease: Correlation with Clinical Outcome 1

George Z. Rassidakis; L. Jeffrey Medeiros; Timothy J. McDonnell; Simonetta Viviani; Valeria Bonfante; Gianpaolo Nadali; Theodoros P. Vassilakopoulos; Roberto Giardini; Marco Chilosi; Christos Kittas; Alessandro M. Gianni; Gianni Bonadonna; Giovanni Pizzolo; Gerassimos A. Pangalis; Fernando Cabanillas; Andreas H. Sarris

Abstract

View articletitled, BAX Expression in Hodgkin and Reed-Sternberg Cells of Hodgkin’s Disease: Correlation with Clinical Outcome<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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p63 Expression Profiles in Human Normal and Tumor Tissues 1

Charles J. Di Como; Marshall J. Urist; Irina Babayan; Marija Drobnjak; Cyrus V. Hedvat; Julie Teruya-Feldstein; Kamal Pohar; Axel Hoos; Carlos Cordon-Cardo

Abstract

View articletitled, p63 Expression Profiles in Human Normal and Tumor Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Intraclonal Homogeneity of Clonotypic Immunoglobulin M and Diversity of Nonclinical Post-Switch Isotypes in Multiple Myeloma: Insights into the Evolution of the Myeloma Clone 1

Brian J. Taylor; Julie A. Pittman; Karen Seeberger; Michael J. Mant; Tony Reiman; Andrew R. Belch; Linda M. Pilarski

Abstract

View articletitled, Intraclonal Homogeneity of Clonotypic Immunoglobulin M and Diversity of Nonclinical Post-Switch Isotypes in Multiple Myeloma: Insights into the Evolution of the Myeloma Clone<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Aberrant Promoter Methylation Profile of Prostate Cancers and Its Relationship to Clinicopathological Features 1

Riichiroh Maruyama; Shinichi Toyooka; Kiyomi O. Toyooka; Arvind K. Virmani; Sabine Zöchbauer-Müller; Alfredo J. Farinas; John D. Minna; John McConnell; Eugene P. Frenkel; Adi F. Gazdar

Abstract

View articletitled, Aberrant Promoter Methylation Profile of Prostate Cancers and Its Relationship to Clinicopathological Features<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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HER-2-positive Breast Carcinomas As a Particular Subset with Peculiar Clinical Behaviors 1

Sylvie Ménard; Andrea Balsari; Patrizia Casalini; Elda Tagliabue; Manuela Campiglio; Rosaria Bufalino; Natale Cascinelli

Abstract

View articletitled, HER-2-positive Breast Carcinomas As a Particular Subset with Peculiar Clinical Behaviors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Gain of 5p15 Detected by Comparative Genomic Hybridization as an Independent Marker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma 1

Takashi Ueno; Akira Tangoku; Shigefumi Yoshino; Toshihiro Abe; Hiroaki Toshimitsu; Tomoko Furuya; Shigeto Kawauchi; Atsunori Oga; Masaaki Oka; Kohsuke Sasaki

Abstract

View articletitled, Gain of 5p15 Detected by Comparative Genomic Hybridization as an Independent Marker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Detection of Genetic Prognostic Markers in Uveal Melanoma Biopsies Using Fluorescence in Situ Hybridization

Nicole C. Naus; Anette C. A. Verhoeven; Ellen van Drunen; Rosalyn Slater; Cornelia M. Mooy; Dion A. Paridaens; Grégorius P. M. Luyten; Annelies de Klein

Abstract

View articletitled, Detection of Genetic Prognostic Markers in Uveal Melanoma Biopsies Using Fluorescence in Situ Hybridization

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Characterization of the HER-2/neu Oncogene by Immunohistochemical and Fluorescence in Situ Hybridization Analysis in Oral and Oropharyngeal Squamous Cell Carcinoma

Atif J. Khan; Bonnie L. King; Benjamin D. Smith; Grace L. Smith; Michael P. DiGiovanna; Darryl Carter; Bruce G. Haffty

Abstract

View articletitled, Characterization of the HER-2/neu Oncogene by Immunohistochemical and Fluorescence in Situ Hybridization Analysis in Oral and Oropharyngeal Squamous Cell Carcinoma

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Utilization of the Human Genome Sequence Localizes Human Papillomavirus Type 16 DNA Integrated into the TNFAIP2 Gene in a Fatal Cervical Cancer from a 39-Year-Old Woman

Mark H. Einstein; Yvette Cruz; Mustafa K. El-Awady; Nicolas C. Popescu; Joseph A. DiPaolo; Marc van Ranst; Anna S. Kadish; Seymour Romney; Carolyn D. Runowicz; Robert D. Burk

Abstract

View articletitled, Utilization of the Human Genome Sequence Localizes Human Papillomavirus Type 16 DNA Integrated into the TNFAIP2 Gene in a Fatal Cervical Cancer from a 39-Year-Old Woman

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Experimental Therapeutics, Preclinical Pharmacology

The Ras Inhibitor S-trans,trans-Farnesylthiosalicylic Acid Chemosensitizes Human Tumor Cells Without Causing Resistance 1

Mali Gana-Weisz; Julius Halaschek-Wiener; Burkhard Jansen; Galit Elad; Ronit Haklai; Yoel Kloog

Abstract

View articletitled, The Ras Inhibitor S-trans,trans-Farnesylthiosalicylic Acid Chemosensitizes Human Tumor Cells Without Causing Resistance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Arsenic Trioxide Cytotoxicity in Steroid and Chemotherapy-resistant Myeloma Cell Lines: Enhancement of Apoptosis by Manipulation of Cellular Redox State 1

Ronald B. Gartenhaus; Sheila N. Prachand; Mary Paniaqua; Yuyu Li; Leo I. Gordon

Abstract

View articletitled, Arsenic Trioxide Cytotoxicity in Steroid and Chemotherapy-resistant Myeloma Cell Lines: Enhancement of Apoptosis by Manipulation of Cellular Redox State<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Superior Therapeutic Profile of Poly-l-Glutamic Acid-Paclitaxel Copolymer Compared with Taxol in Xenogeneic Compartmental Models of Human Ovarian Carcinoma 1

Edmond Auzenne; Nicholas J. Donato; Chun Li; Elena Leroux; Roger E. Price; David Farquhar; Jim Klostergaard

Abstract

View articletitled, Superior Therapeutic Profile of Poly-l-Glutamic Acid-Paclitaxel Copolymer Compared with Taxol in Xenogeneic Compartmental Models of Human Ovarian Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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MS-209, a Quinoline-type Reversal Agent, Potentiates Antitumor Efficacy of Docetaxel in Multidrug-resistant Solid Tumor Xenograft Models 1

Mikihiko Naito; Yasuhiro Matsuba; Shigeo Sato; Hiroshi Hirata; Takashi Tsuruo

Abstract

View articletitled, MS-209, a Quinoline-type Reversal Agent, Potentiates Antitumor Efficacy of Docetaxel in Multidrug-resistant Solid Tumor Xenograft Models<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of PDE3B Augments PDE4 Inhibitor-induced Apoptosis in a Subset of Patients with Chronic Lymphocytic Leukemia 1

Eunyi Moon; Richard Lee; Richard Near; Lewis Weintraub; Sharon Wolda; Adam Lerner

Abstract

View articletitled, Inhibition of PDE3B Augments PDE4 Inhibitor-induced Apoptosis in a Subset of Patients with Chronic Lymphocytic Leukemia<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Paclitaxel Triggers Cell Death Primarily via Caspase-independent Routes in the Non-Small Cell Lung Cancer Cell Line NCI-H460 1

Cynthia Huisman; Carlos G. Ferreira; Linda E. Bröker; Jose A. Rodriguez; Egbert F. Smit; Pieter E. Postmus; Frank A. E. Kruyt; Giuseppe Giaccone

Abstract

View articletitled, Paclitaxel Triggers Cell Death Primarily via Caspase-independent Routes in the Non-Small Cell Lung Cancer Cell Line NCI-H460<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Protein Kinase A RIα Antisense Inhibition of PC3M Prostate Cancer Cell Growth: Bcl-2 Hyperphosphorylation, Bax Up-Regulation, and Bad-Hypophosphorylation

Yee Sook Cho; Meyoung-Kon Kim; Langzhu Tan; Rakesh Srivastava; Sudhir Agrawal; Yoon S. Cho-Chung

Abstract

View articletitled, Protein Kinase A RIα Antisense Inhibition of PC3M Prostate Cancer Cell Growth: Bcl-2 Hyperphosphorylation, Bax Up-Regulation, and Bad-Hypophosphorylation

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Letters to the Editor

Correspondence re: Seki et al., Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification. Clin. Cancer Res., 7: 1976–1981, 2001.

Kirsten S. Hindle; Katherine Kirkpatrick; Kefah Mokbel

Extract

View articletitled, Correspondence re: Seki et al., Diagnosis of pancreatic adenocarcinoma by detection of human telomerase reverse transcriptase messenger RNA in pancreatic juice with sample qualification. Clin. Cancer Res., 7: 1976–1981, 2001.

Issues

Editorial

The Biology Behind

Cancer Prevention by Delay1: Commentary re: J. A. O’Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314–346, 2002.

Special Article

Advances in Brief

Molecular Oncology, Markers, Clinical Correlates

Experimental Therapeutics, Preclinical Pharmacology

Regular Articles

Clinical Trials

Cell Biology

Research Articles

Molecular Oncology, Markers, Clinical Correlates

Experimental Therapeutics, Preclinical Pharmacology

Letters to the Editor

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only

Cancer Prevention by Delay 1: Commentary re: J. A. O’Shaughnessy et al., Treatment and Prevention of Intraepithelial Neoplasia: An Important Target for Accelerated New Agent Development. Clin. Cancer Res., 8: 314–346, 2002.