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The Biology Behind

The Battle between Tumor Suppressors: Is Gene Therapy Using p16^INK4a More Efficacious Than p53 for Treatment of Ovarian Carcinoma?1: Commentary re: S. C. Modesitt et al., In Vitro and In Vivo Adenovirus-mediated p53 and p16 Tumor Suppressor Therapy in Ovarian Cancer. Clin. Cancer Res., 7: 1765–1772, 2001.

Maureen E. Murphy

View articletitled, The Battle between Tumor Suppressors: Is Gene Therapy Using p16INK4a More Efficacious Than p53 for Treatment of Ovarian Carcinoma?<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>: Commentary re: S. C. Modesitt et al., In Vitro and In Vivo Adenovirus-mediated p53 and p16 Tumor Suppressor Therapy in Ovarian Cancer. Clin. Cancer Res., 7: 1765–1772, 2001.

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Report from the FDA

Approval Summary: Gemtuzumab Ozogamicin in Relapsed Acute Myeloid Leukemia

Peter F. Bross; Julie Beitz; Gang Chen; Xiao Hong Chen; Eric Duffy; Lydia Kieffer; Sandip Roy; Rajeshwari Sridhara; Atiqur Rahman; Grant Williams; Richard Pazdur

Abstract

View articletitled, Approval Summary: Gemtuzumab Ozogamicin in Relapsed Acute Myeloid Leukemia

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Advances in Brief

Induction of Topoisomerase II Activity after ErbB2 Activation Is Associated with a Differential Response to Breast Cancer Chemotherapy

L. N. Harris; Li Yang; Vlayka Liotcheva; Samuel Pauli; James Dirk Iglehart; O. Michael Colvin; Tao Shih Hsieh

Abstract

View articletitled, Induction of Topoisomerase II Activity after ErbB2 Activation Is Associated with a Differential Response to Breast Cancer Chemotherapy

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Therapy of Disseminated B-Cell Lymphoma Xenografts in Severe Combined Immunodeficient Mice with an Anti-CD74 Antibody Conjugated with ¹¹¹Indium, ⁶⁷Gallium, or ⁹⁰Yttrium 1

Rita Ochakovskaya; Louis Osorio; David M. Goldenberg; M. Jules Mattes

Abstract

View articletitled, Therapy of Disseminated B-Cell Lymphoma Xenografts in Severe Combined Immunodeficient Mice with an Anti-CD74 Antibody Conjugated with 111Indium, 67Gallium, or 90Yttrium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Paclitaxel and Docetaxel Enhance the Metabolism of Doxorubicin to Toxic Species in Human Myocardium 1

Giorgio Minotti; Antonella Saponiero; Sabrina Licata; Pierantonio Menna; Antonio M. Calafiore; Giovanni Teodori; Luca Gianni

Abstract

View articletitled, Paclitaxel and Docetaxel Enhance the Metabolism of Doxorubicin to Toxic Species in Human Myocardium<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Molecular Determination of Perivesical and Lymph Node Metastasis after Radical Cystectomy for Urothelial Carcinoma of the Bladder

M. Jabed Seraj; Alexander R. Thomas; Joseph L. Chin; Dan Theodorescu

Abstract

View articletitled, Molecular Determination of Perivesical and Lymph Node Metastasis after Radical Cystectomy for Urothelial Carcinoma of the Bladder

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Persistence of Genetically Altered Fields in Head and Neck Cancer Patients: Biological and Clinical Implications 1

Maarten P. Tabor; Ruud H. Brakenhoff; Viola M. M. van Houten; J. Alain Kummer; Mireille H. J. Snel; Peter J. F. Snijders; Gordon B. Snow; C. René Leemans; Boudewijn J. M. Braakhuis

Abstract

View articletitled, Persistence of Genetically Altered Fields in Head and Neck Cancer Patients: Biological and Clinical Implications<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Tumor Angiogenesis Is Associated with MUC1 Overexpression and Loss of Prostate-specific Antigen Expression in Prostate Cancer

Ilias Papadopoulos; Efthimios Sivridis; Alexandra Giatromanolaki; Michael I. Koukourakis

Abstract

View articletitled, Tumor Angiogenesis Is Associated with MUC1 Overexpression and Loss of Prostate-specific Antigen Expression in Prostate Cancer

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Detection of Genetic Alterations in Esophageal Squamous Cell Carcinomas and Adjacent Normal Epithelia by Comparative DNA Fingerprinting Using Inter-Simple Sequence Repeat PCR 1

Johnny C. O. Tang; King Y. Lam; Simon Law; John Wong; Gopesh Srivastava

Abstract

View articletitled, Detection of Genetic Alterations in Esophageal Squamous Cell Carcinomas and Adjacent Normal Epithelia by Comparative DNA Fingerprinting Using Inter-Simple Sequence Repeat PCR<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Fez1/Lzts1 Alterations in Gastric Carcinoma 1

Andrea Vecchione; Hideshi Ishii; Yih-Horng Shiao; Francesco Trapasso; Massimo Rugge; Joseph F. Tamburrino; Yoshiki Murakumo; Hansjuerg Alder; Carlo M. Croce; Raffaele Baffa

Abstract

View articletitled, Fez1/Lzts1 Alterations in Gastric Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Human Endogenous Retrovirus K Envelope Transcripts in Human Breast Cancer 1

Feng Wang-Johanning; Andra R. Frost; Gary L. Johanning; M. B. Khazaeli; Albert F. LoBuglio; Denise R. Shaw; Theresa V. Strong

Abstract

View articletitled, Expression of Human Endogenous Retrovirus K Envelope Transcripts in Human Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Regular Articles

Clinical Trials

Radioimmunotherapy with ¹¹¹In/⁹⁰Y-2IT-BAD-m170 for Metastatic Prostate Cancer 1

Robert T. O'Donnell; Sally J. DeNardo; Aina Yuan; Sui Shen; Carol M. Richman; Primo N. Lara; Irwin J. Griffith; Desiree S. Goldstein; David L. Kukis; Gerard S. Martinez; Gary R. Mirick; Gerald L. DeNardo; Frederick J. Meyers

Abstract

View articletitled, Radioimmunotherapy with 111In/90Y-2IT-BAD-m170 for Metastatic Prostate Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Phase I Trial of 96-Hour Continuous Infusion of Dexrazoxane in Patients with Advanced Malignancies 1

Merry L. Tetef; Timothy W. Synold; Warren Chow; Lucille Leong; Kim Margolin; Robert Morgan; James Raschko; Stephen Shibata; George Somlo; Yun Yen; Susan Groshen; Kay Johnson; Heinz-Josef Lenz; David Gandara; James H. Doroshow

Abstract

View articletitled, Phase I Trial of 96-Hour Continuous Infusion of Dexrazoxane in Patients with Advanced Malignancies<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Chemotherapy Response of Breast Cancer Depends on HER-2 Status and Anthracycline Dose Intensity in the Neoadjuvant Setting

Thierry Petit; Christian Borel; Jean-Pierre Ghnassia; Jean-François Rodier; Anne Escande; Ricardo Mors; Pierre Haegelé

Abstract

View articletitled, Chemotherapy Response of Breast Cancer Depends on HER-2 Status and Anthracycline Dose Intensity in the Neoadjuvant Setting

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Survival of Tumor Cells in Stem Cell Preparations and Bone Marrow of Patients with High-Risk or Metastatic Breast Cancer after Receiving Dose-intensive or High-Dose Chemotherapy 1

Sabine Kasimir-Bauer; Susanne Mayer; Peter Bojko; David Borquez; Rainer Neumann; Siegfried Seeber

Abstract

View articletitled, Survival of Tumor Cells in Stem Cell Preparations and Bone Marrow of Patients with High-Risk or Metastatic Breast Cancer after Receiving Dose-intensive or High-Dose Chemotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Phase II Trial of the Cyclin-dependent Kinase Inhibitor Flavopiridol in Patients with Previously Untreated Stage IV Non-Small Cell Lung Cancer 1

Geoffrey I. Shapiro; Jeffrey G. Supko; Angus Patterson; Cathy Lynch; Joan Lucca; Patrick F. Zacarola; Alona Muzikansky; John J. Wright; Thomas J. Lynch, Jr.; Barrett J. Rollins

Abstract

View articletitled, A Phase II Trial of the Cyclin-dependent Kinase Inhibitor Flavopiridol in Patients with Previously Untreated Stage IV Non-Small Cell Lung Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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A Phase I Trial of Carboxyamido-triazole and Paclitaxel for Relapsed Solid Tumors: Potential Efficacy of the Combination and Demonstration of Pharmacokinetic Interaction

Elise C. Kohn; Eddie Reed; Gisele A. Sarosy; Lori Minasian; Kenneth S. Bauer; Frieda Bostick-Bruton; Vyta Kulpa; Eichi Fuse; Anne Tompkins; Marianne Noone; Barry Goldspiel; James Pluda; William D. Figg; Lance A. Liotta

Abstract

View articletitled, A Phase I Trial of Carboxyamido-triazole and Paclitaxel for Relapsed Solid Tumors: Potential Efficacy of the Combination and Demonstration of Pharmacokinetic Interaction

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The P-Glycoprotein Antagonist PSC 833 Increases the Plasma Concentrations of 6α-Hydroxypaclitaxel, a Major Metabolite of Paclitaxel 1

Min H. Kang; William D. Figg; Yuichi Ando; Mikhail V. Blagosklonny; David Liewehr; Tito Fojo; Susan E. Bates

Abstract

View articletitled, The P-Glycoprotein Antagonist PSC 833 Increases the Plasma Concentrations of 6α-Hydroxypaclitaxel, a Major Metabolite of Paclitaxel<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Research Articles

Molecular Oncology

Defective Transforming Growth Factor β Signaling Pathway in Head and Neck Squamous Cell Carcinoma as Evidenced by the Lack of Expression of Activated Smad2 1

Carlos A. Muro-Cacho; Karen Rosario-Ortiz; Sandra Livingston; Teresita Muñoz-Antonia

Abstract

View articletitled, Defective Transforming Growth Factor β Signaling Pathway in Head and Neck Squamous Cell Carcinoma as Evidenced by the Lack of Expression of Activated Smad2<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Tumor Angiogenesis and Its Possible Role in Intravasation of Colorectal Epithelial Cells

Yu-Wen Tien; King-Jen Chang; Yung-Ming Jeng; Po-Huang Lee; Ming-Shi Wu; Jaw-Town Lin; Su-Ming Hsu

Abstract

View articletitled, Tumor Angiogenesis and Its Possible Role in Intravasation of Colorectal Epithelial Cells

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Elevated Serum Levels of Type I Collagen Degradation Marker ICTP and Tissue Inhibitor of Metalloproteinase (TIMP) 1 Are Associated with Poor Prognosis in Lung Cancer

Sanna Ylisirniö; Matti Höyhtyä; Riitta Mäkitaro; Paavo Pääakkö; Juha Risteli; Vuokko L. Kinnula; Taina Turpeenniemi-Hujanen; Arja Jukkola

Abstract

View articletitled, Elevated Serum Levels of Type I Collagen Degradation Marker ICTP and Tissue Inhibitor of Metalloproteinase (TIMP) 1 Are Associated with Poor Prognosis in Lung Cancer

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Diagnostic Strategy for Analytical Scanning of BRCA1 Gene by Fluorescence-assisted Mismatch Analysis Using Large, Bifluorescently Labeled Amplicons 1

Enrico Ricevuto; Hagay Sobol; Dominique Stoppa-Lyonnet; Alberto Gulino; Paolo Marchetti; Corrado Ficorella; Stefano Martinotti; Tommaso Meo; Mario Tosi

Abstract

View articletitled, Diagnostic Strategy for Analytical Scanning of BRCA1 Gene by Fluorescence-assisted Mismatch Analysis Using Large, Bifluorescently Labeled Amplicons<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Prediction of Peritoneal Micrometastasis by Peritoneal Lavaged Cytology and Reverse Transcriptase-Polymerase Chain Reaction for Matrix Metalloproteinase-7 mRNA

Yutaka Yonemura; Takashi Fujimura; Itasu Ninomiya; Byung-Sik Kim; Etsurou Bandou; Toshiharu Sawa; Kazuo Kinoshita; Yoshio Endo; Kazuo Sugiyama; Takuma Sasaki

Abstract

View articletitled, Prediction of Peritoneal Micrometastasis by Peritoneal Lavaged Cytology and Reverse Transcriptase-Polymerase Chain Reaction for Matrix Metalloproteinase-7 mRNA

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The Expression of the Urokinase Plasminogen Activator System in Metastatic Murine Osteosarcoma: An in Vivo Mouse Model 1

Jane Lisette Fisher; Peter Scott Mackie; Monique Louise Howard; Hong Zhou; Peter Fook Meng Choong

Abstract

View articletitled, The Expression of the Urokinase Plasminogen Activator System in Metastatic Murine Osteosarcoma: An in Vivo Mouse Model<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression of Hypoxia-inducible Factor 1α in Epithelial Ovarian Tumors: Its Impact on Prognosis and on Response to Chemotherapy 1

Peter Birner; Monika Schindl; Andreas Obermair; Gerhard Breitenecker; Georg Oberhuber

Abstract

View articletitled, Expression of Hypoxia-inducible Factor 1α in Epithelial Ovarian Tumors: Its Impact on Prognosis and on Response to Chemotherapy<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Evaluation of the United States Food and Drug Administration-approved Scoring and Test System of HER-2 Protein Expression in Breast Cancer

Peter Birner; Georg Oberhuber; Josephine Stani; Cornelia Reithofer; Hellmut Samonigg; Hubert Hausmaninger; Ernst Kubista; Werner Kwasny; Daniela Kandioler-Eckersberger; Michael Gnant; Raimund Jakesz; the Austrian Breast & Colorectal Cancer Study Group

Abstract

View articletitled, Evaluation of the United States Food and Drug Administration-approved Scoring and Test System of HER-2 Protein Expression in Breast Cancer

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Alterations of the 9p21 and 9q33 Chromosomal Bands in Clinical Bladder Cancer Specimens by Fluorescence in Situ Hybridization 1

Walter M. Stadler; Gary Steinberg; Ximing Yang; Fitsum Hagos; Craig Turner; Olufunmilayo I. Olopade

Abstract

View articletitled, Alterations of the 9p21 and 9q33 Chromosomal Bands in Clinical Bladder Cancer Specimens by Fluorescence in Situ Hybridization<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Loss of H-Cadherin Protein Expression in Human Non-Small Cell Lung Cancer Is Associated with Tumorigenicity 1

Yun Zhong; Yara Delgado; Jorge Gomez; Sam W. Lee; Roman Perez-Soler

Abstract

View articletitled, Loss of H-Cadherin Protein Expression in Human Non-Small Cell Lung Cancer Is Associated with Tumorigenicity<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Nucleotide Substitution in the Ectodomain of TRAIL Receptor DR4 Is Associated with Lung Cancer and Head and Neck Cancer 1

Michael J. Fisher; Arvind K. Virmani; Li Wu; Richard Aplenc; Jeffrey C. Harper; Steven M. Powell; Timothy R. Rebbeck; David Sidransky; Adi F. Gazdar; Wafik S. El-Deiry

Abstract

View articletitled, Nucleotide Substitution in the Ectodomain of TRAIL Receptor DR4 Is Associated with Lung Cancer and Head and Neck Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Quantitation of Marrow Disease in Neuroblastoma by Real-Time Reverse Transcription-PCR 1

Irene Y. Cheung; Nai-Kong V. Cheung

Abstract

View articletitled, Quantitation of Marrow Disease in Neuroblastoma by Real-Time Reverse Transcription-PCR<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Expression Pattern of Fatty Acid-binding Proteins in Human Normal and Cancer Prostate Cells and Tissues 1

Rina Das; Rasha Hammamieh; Roger Neill; Mona Melhem; Marti Jett

Abstract

View articletitled, Expression Pattern of Fatty Acid-binding Proteins in Human Normal and Cancer Prostate Cells and Tissues<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Measures of Cell Turnover (Proliferation and Apoptosis) and Their Association with Survival in Breast Cancer 1

Shuqing Liu; Susan M. Edgerton; Dan H. Moore, II; Ann D. Thor

Abstract

View articletitled, Measures of Cell Turnover (Proliferation and Apoptosis) and Their Association with Survival in Breast Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Frequent Death-associated Protein Kinase Promoter Hypermethylation in Multiple Myeloma 1

Margaret H. L. Ng; K. W. To; K. W. Lo; S. Chan; K. S. Tsang; S. H. Cheng; H. K. Ng

Abstract

View articletitled, Frequent Death-associated Protein Kinase Promoter Hypermethylation in Multiple Myeloma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Clinicopathological and Molecular Evidence Indicating the Independence of Bronchioloalveolar Components from Other Subtypes of Human Peripheral Lung Adenocarcinoma

Takaomi Koga; Shuichi Hashimoto; Kenji Sugio; Ichiro Yoshino; Sepideh Mojtahedzadeh; Yoshio Matsuo; Yoshikazu Yonemitsu; Keizo Sugimachi; Katsuo Sueishi

Abstract

View articletitled, Clinicopathological and Molecular Evidence Indicating the Independence of Bronchioloalveolar Components from Other Subtypes of Human Peripheral Lung Adenocarcinoma

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Pathological Features and BRCA1 Mutation Screening in Premenopausal Breast Cancer Patients 1

Jenny Chang; Susan G. Hilsenbeck; Jen Hwei Sng; John Wong; G. C. Ragu

Abstract

View articletitled, Pathological Features and BRCA1 Mutation Screening in Premenopausal Breast Cancer Patients<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Association of Urokinase-Type Plasminogen Activator and Its Inhibitor with Disease Progression and Prognosis in Ovarian Cancer 1

Gottfried Konecny; Michael Untch; Astrid Pihan; Rainer Kimmig; Martina Gropp; Petra Stieber; Herrmann Hepp; Dennis Slamon; Mark Pegram

Abstract

View articletitled, Association of Urokinase-Type Plasminogen Activator and Its Inhibitor with Disease Progression and Prognosis in Ovarian Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Widespread Expression of Thioredoxin and Thioredoxin Reductase in Non-Small Cell Lung Carcinoma 1

Ylermi Soini; Katriina Kahlos; Ulla Näpänkangas; Riitta Kaarteenaho-Wiik; Marjaana Säily; Pirjo Koistinen; Paavo Pääakkö; Arne Holmgren; Vuokko L. Kinnula

Abstract

View articletitled, Widespread Expression of Thioredoxin and Thioredoxin Reductase in Non-Small Cell Lung Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Experimental Therapeutics, Preclinical Pharmacology

Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition 1

Lorina Dudkin; Michael B. Dilling; Pamela J. Cheshire; Franklin C. Harwood; Melinda Hollingshead; Susan G. Arbuck; Robert Travis; Edward A. Sausville; Peter J. Houghton

Abstract

View articletitled, Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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In Vitro and in Vivo Adenovirus-mediated p53 and p16 Tumor Suppressor Therapy in Ovarian Cancer 1: See The Biology Behind: M. E. Murphy, The Battle between Tumor Suppressors: Is Gene Therapy Using p16^INK4a More Efficacious Than p53 for Treatment of Ovarian Carcinoma? Clin. Cancer Res., 7: 1487–1489, 2001.

Susan C. Modesitt; Pedro Ramirez; Zheife Zu; Diane Bodurka-Bevers; David Gershenson; Judith K. Wolf

Abstract

View articletitled, In Vitro and in Vivo Adenovirus-mediated p53 and p16 Tumor Suppressor Therapy in Ovarian Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>: See The Biology Behind: M. E. Murphy, The Battle between Tumor Suppressors: Is Gene Therapy Using p16INK4a More Efficacious Than p53 for Treatment of Ovarian Carcinoma? Clin. Cancer Res., 7: 1487–1489, 2001.

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Interleukin-6 Induces Androgen Responsiveness in Prostate Cancer Cells through Up-Regulation of Androgen Receptor Expression 1

Din-Lii Lin; Mary C. Whitney; Zhi Yao; Evan T. Keller

Abstract

View articletitled, Interleukin-6 Induces Androgen Responsiveness in Prostate Cancer Cells through Up-Regulation of Androgen Receptor Expression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Differential Sensitivity of Normal and Malignant Breast Epithelial Cells to Genistein Is Partly Mediated by p21^WAF1 1

Sunil Upadhyay; Madhavi Neburi; Sreenivasa R. Chinni; Samir Alhasan; Fred Miller; Fazlul H. Sarkar

Abstract

View articletitled, Differential Sensitivity of Normal and Malignant Breast Epithelial Cells to Genistein Is Partly Mediated by p21WAF1<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Inhibition of Insulin-like Growth Factor I Receptor Increases the Antitumor Activity of Doxorubicin and Vincristine against Ewing’s Sarcoma Cells 1

Stefania Benini; Maria Cristina Manara; Nicola Baldini; Vanessa Cerisano; Massimo Serra; Mario Mercuri; Pier-Luigi Lollini; Patrizia Nanni; Piero Picci; Katia Scotlandi

Abstract

View articletitled, Inhibition of Insulin-like Growth Factor I Receptor Increases the Antitumor Activity of Doxorubicin and Vincristine against Ewing’s Sarcoma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Multidrug Resistance Proteins MRP3, MRP1, and MRP2 in Lung Cancer: Correlation of Protein Levels with Drug Response and Messenger RNA Levels 1

Leah C. Young; Barbara G. Campling; Susan P. C. Cole; Roger G. Deeley; James H. Gerlach

Abstract

View articletitled, Multidrug Resistance Proteins MRP3, MRP1, and MRP2 in Lung Cancer: Correlation of Protein Levels with Drug Response and Messenger RNA Levels<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Carboxymethyl Benzylamide Dextran and Tamoxifen Combination Inhibits Tumor Growth and Angiogenesis 1

Rozita Bagheri-Yarmand; Yamina Hamma-Kourbali; Philippe Bissieres; Jean-François Morère; Michel Crépin

Abstract

View articletitled, Carboxymethyl Benzylamide Dextran and Tamoxifen Combination Inhibits Tumor Growth and Angiogenesis<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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IL (Interleukin)-1α Promotes Nuclear Factor-κB and AP-1-induced IL-8 Expression, Cell Survival, and Proliferation in Head and Neck Squamous Cell Carcinomas 1

Jeffrey S. Wolf; Zhong Chen; Gang Dong; John B. Sunwoo; Caren C. Bancroft; David E. Capo; Ning T. Yeh; Naofumi Mukaida; Carter Van Waes

Abstract

View articletitled, IL (Interleukin)-1α Promotes Nuclear Factor-κB and AP-1-induced IL-8 Expression, Cell Survival, and Proliferation in Head and Neck Squamous Cell Carcinomas<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

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Preferential Induction of Apoptosis by Interferon (IFN)-β Compared with IFN-α2: Correlation with TRAIL/Apo2L Induction in Melanoma Cell Lines

Mamta Chawla-Sarkar; Douglas W. Leaman; Ernest C. Borden

Abstract

View articletitled, Preferential Induction of Apoptosis by Interferon (IFN)-β Compared with IFN-α2: Correlation with TRAIL/Apo2L Induction in Melanoma Cell Lines

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Issues

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Experimental Therapeutics, Preclinical Pharmacology

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