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Issues

Volume 7, Issue 11
1 November 2001
Clinical Cancer Research Cover Image for Volume 7, Issue 11
All Issues
ISSN 1078-0432
EISSN 1557-3265

Editorial

Thalidomide, Cyclooxygenase-2, and Angiogenesis: Potential for Therapy
Amir Onn; Jennifer E. Tseng; Roy S. Herbst
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Minireview

Strategies for Enzyme/Prodrug Cancer Therapy1
Guang Xu; Howard L. McLeod
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The Biology Behind

A Proteomics Approach to Find a New Breast Cancer-specific Antigenic Marker: Commentary re: Protemics-based Identification of RS/DJ-1 as a Novel Circulating Tumor Antigen in Breast Cancer. Clin. Cancer Res., 7: 3328–3335, 2001.
Ryuji Kobayashi
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Advances in Brief

Molecular Oncology, Markers, Clinical Correlates
Proteomics-based Identification of RS/DJ-1 as a Novel Circulating Tumor Antigen in Breast Cancer1
François Le Naour; David E. Misek; Melissa C. Krause; L. Deneux; Thomas J. Giordano; S. Scholl; Samir M. Hanash
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Experimental Therapeutics, Preclinical Pharmacology
The Investigational New Drug XK469 Induces G2-M Cell Cycle Arrest by p53-dependent and -independent Pathways1
Zhenhua Ding; Ralph E. Parchment; Patricia M. LoRusso; Jun-Ying Zhou; Jun Li; Theodore S. Lawrence; Yi Sun; Gen Sheng Wu
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Characterization of HLA-A3-restricted Cytotoxic T Lymphocytes Reactive against the Widely Expressed Tumor Antigen Telomerase1
Robert H. Vonderheide; Karen S. Anderson; William C. Hahn; Mark O. Butler; Joachim L. Schultze; Lee M. Nadler
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Thalidomide and Its Analogues Inhibit Lipopolysaccharide-mediated Induction of Cyclooxygenase-21
Junya Fujita; Juan R. Mestre; Jerome B. Zeldis; Kotha Subbaramaiah; Andrew J. Dannenberg
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Regular Articles

Clinical Trials
A Randomized Clinical Trial of 4-Hydroxyphenylretinamide for High-Grade Squamous Intraepithelial Lesions of the Cervix1
Michele Follen; E. Neely Atkinson; David Schottenfeld; Anais Malpica; Loyd West; Scott Lippman; Changping Zou; Walter N. Hittelman; Reuben Lotan; Waun Ki Hong
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Tissue Examination to Monitor Antiangiogenic Therapy: A Phase I Clinical Trial with Endostatin1
Christoph Mundhenke; James P. Thomas; George Wilding; Fred T. Lee; Fred Kelzc; Rick Chappell; Rosemary Neider; Linda A. Sebree; Andreas Friedl
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Phase II Trial of Cisplatin, Interferon α-2b, Doxorubicin, and 5-Fluorouracil for Biliary Tract Cancer1
Yehuda Z. Patt; Manal M. Hassan; Richard D. Lozano; Kimberly A. Waugh; Ashraful M. Hoque; Adam I. Frome; Sandeep Lahoti; Lee Ellis; J. Nicolas Vauthey; Steven A. Curley; Isac I. Schnirer; Isaac Raijman
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Cancer Biology, Immunology, Cytokines
MCF-10A-NeoST: A New Cell System for Studying Cell-ECM and Cell-Cell Interactions in Breast Cancer1
Nicole Dodge Zantek; Jennifer Walker-Daniels; Jane Stewart; Rhonda K. Hansen; Daniel Robinson; Hui Miao; Bingcheng Wang; Hsing-Jien Kung; Mina J. Bissell; Michael S. Kinch
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Research Articles

Molecular Oncology, Markers, Clinical Correlates
Vascular Endothelial Growth Factor in Newly Diagnosed and Recurrent Childhood Acute Lymphoblastic Leukemia as Measured by Real-Time Quantitative Polymerase Chain Reaction
Reet Koomagi; Felix Zintl; Axel Sauerbrey; Manfred Volm
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Nitric Oxide, Prostanoids, Cyclooxygenase, and Angiogenesis in Colon and Breast Cancer1
Richard J. Bing; Masaru Miyataka; Kathryn A. Rich; Nicholas Hanson; Xuedong Wang; Henry D. Slosser; Shan-Rong Shi
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Analysis of Normal Epithelial Cell Specific-1 (NES1)/Kallikrein 10 mRNA Expression by in Situ Hybridization, a Novel Marker for Breast Cancer1
Sanjay Dhar; Rohit Bhargava; Michael Yunes; Biao Li; Jaya Goyal; Stephen P. Naber; David E. Wazer; Vimla Band
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Hypoxia-regulated Carbonic Anhydrase-9 (CA9) Relates to Poor Vascularization and Resistance of Squamous Cell Head and Neck Cancer to Chemoradiotherapy
Michael I. Koukourakis; Alexandra Giatromanolaki; Efthimios Sivridis; Konstantinos Simopoulos; Jaromir Pastorek; Charles C. Wykoff; Kevin C. Gatter; Adrian L. Harris
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Chromosome 6 Abnormalities in Ovarian Surface Epithelial Tumors of Borderline Malignancy Suggest a Genetic Continuum in the Progression Model of Ovarian Neoplasms1
Maria Grazia Tibiletti; Barbara Bernasconi; Daniela Furlan; Paola Bressan; Roberta Cerutti; Carla Facco; Massimo Franchi; Cristina Riva; Raffaella Cinquetti; Carlo Capella; Roberto Taramelli
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Evaluation of Angiogenesis in Non-small Cell Lung Cancer: Comparison between Anti-CD34 Antibody and Anti-CD105 Antibody1
Fumihiro Tanaka; Yosuke Otake; Kazuhiro Yanagihara; Yozo Kawano; Ryo Miyahara; Mio Li; Tomoko Yamada; Nobuharu Hanaoka; Kenji Inui; Hiromi Wada
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Single Nucleotide Polymorphisms in the Human Reduced Folate Carrier: Characterization of a High-Frequency G/A Variant at Position 80 and Transport Properties of the His27 and Arg27 Carriers1
Johnathan R. Whetstine; Andrew J. Gifford; Teah Witt; Xiang Y. Liu; Robin M. Flatley; Murray Norris; Michelle Haber; Jeffrey W. Taub; Y. Ravindranath; Larry H. Matherly
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Quantitative Reverse Transcription-Polymerase Chain Reaction Detection of Cytokeratin 20 in Noncolorectal Lymph Nodes1
Richie Soong; Kurt Beyser; Oliver Basten; Andreas Kalbe; Josef Rueschoff; Karim Tabiti
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Inverse Correlation of Thioredoxin Expression with Estrogen Receptor- and p53-dependent Tumor Growth in Breast Cancer Tissues1
Yasuo Matsutani; Akira Yamauchi; Rei Takahashi; Masaya Ueno; Kiyotugu Yoshikawa; Kazuo Honda; Hajime Nakamura; Hironori Kato; Hiroshi Kodama; Takashi Inamoto; Junji Yodoi; Yoshio Yamaoka
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Expression of METH-1 and METH-2 in Pancreatic Cancer1
Toshihiko Masui; Ryo Hosotani; Shoichiro Tsuji; Yoshiharu Miyamoto; Seichi Yasuda; Jun Ida; Sanae Nakajima; Michiya Kawaguchi; Hiroyuki Kobayashi; Masayuki Koizumi; Eiji Toyoda; Sidhartha Tulachan; Shigeki Arii; Ryuichiro Doi; Masayuki Imamura
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Microsatellite Instability in Thyroid Cancer: Hot Spots, Clinicopathological Implications, and Prognostic Significance1
Masamitsu Onda; Izumi Nakamura; Shinichi Suzuki; Seiichi Takenoshita; Carl-Henrik Brogren; Sabina Stampanoni; Daisy Li; Nicholas Rampino
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Prognostic Significance of Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 in Voided Urine Samples from Patients with Transitional Cell Carcinoma of the Bladder1
Garrett C. Durkan; Joyce E. Nutt; Paul H. Rajjayabun; David E. Neal; John Lunec; J. Kilian Mellon
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Expression Levels of the Nerve Growth Factor Receptors TrkA and p75 in Effusions and Solid Tumors of Serous Ovarian Carcinoma Patients1
Ben Davidson; Philip Lazarovici; Alexandra Ezersky; Jahn M. Nesland; Aasmund Berner; Bjørn Risberg; Claes G. Tropé; Gunnar B. Kristensen; Mariusz Goscinski; Gregg van de Putte; Reuven Reich
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Association of E-Cadherin Germ-Line Alterations with Prostate Cancer1
Tarja Ikonen; Mika Matikainen; Nina Mononen; Eija-R. Hyytinen; Heikki J. Helin; Satu Tommola; Teuvo L. J. Tammela; Eero Pukkala; Johanna Schleutker; Olli-P. Kallioniemi; Pasi A. Koivisto
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Decreased Androgen-responsive Growth of Human Prostate Cancer Is Associated with Increased Genetic Alterations1
Dev Karan; Bruno M. Schmied; Bhavana J. Dave; Uwe A. Wittel; Ming-Fong Lin; Surinder K. Batra
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p16/p14ARF Cell Cycle Regulatory Pathways in Primary Neuroblastoma: p16 Expression Is Associated with Advanced Stage Disease1
Motoko Omura-Minamisawa; Mitchell B. Diccianni; Ray C. Chang; Ayse Batova; Louis J. Bridgeman; Jessica Schiff; Susan L. Cohn; Wendy B. London; Alice L. Yu
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Serum Vascular Endothelial Growth Factor in Breast Cancer: Its Relation with Cancer Type and Estrogen Receptor Status1
Kamal Heer; Harish Kumar; John R. Read; John N. Fox; John R. T. Monson; Michael J. Kerin
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Altered Subcellular Localization of Suppressin, a Novel Inhibitor of Cell-Cycle Entry, Is an Independent Prognostic Factor in Colorectal Adenocarcinomas
Upender Manne; Bernard D. Gary; Denise K. Oelschlager; Heidi L. Weiss; Andra R. Frost; William E. Grizzle
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Prognostic Value of Serum Biological Markers in Patients with Hepatocellular Carcinoma1
Rosanna Parasole; Francesco Izzo; Francesco Perrone; Sandro Pignata; Maria Giulia Galati; Enrico Leonardi; Fabiana Castiglione; Raffaele Orlando; Giuseppe Castello; Giuseppe Esposito; Ciro Gallo; Bruno Daniele
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Apurinic/Apyrimidinic Endonuclease Activity Is Elevated in Human Adult Gliomas1
Michael S. Bobola; A. Blank; Mitchel S. Berger; Bobby A. Stevens; John R. Silber
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Profiling of Differentially Expressed Cancer-related Genes in Esophageal Squamous Cell Carcinoma (ESCC) Using Human Cancer cDNA Arrays: Overexpression of Oncogene MET Correlates with Tumor Differentiation in ESCC
Ying Chuan Hu; King Yin Lam; Simon Law; John Wong; Gopesh Srivastava
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Overrepresentation of the EBAG9 Gene at 8q23 Associated with Early-Stage Breast Cancers1
Michiko Tsuneizumi; Mitsuru Emi; Hisaki Nagai; Haruhito Harada; Goi Sakamoto; Fujio Kasumi; Satoshi Inoue; Teruhisa Kazui; Yusuke Nakamura
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Experimental Therapeutics, Preclinical Pharmacology
Characterization of a Thymidylate Synthase (TS)-inducible Cell Line: A Model System for Studying Sensitivity to TS- and non-TS-targeted Chemotherapies1
Daniel B. Longley; Paul R. Ferguson; John Boyer; Tariq Latif; Maria Lynch; Pamela Maxwell; D. Paul Harkin; Patrick G. Johnston
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Implication of Macrophages in Tumor Rejection Induced by CpG-oligodeoxynucleotides Without Antigen1
Gregor Auf; Antoine F. Carpentier; Lin Chen; Christelle Le Clanche; Jean-Yves Delattre
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Preclinical Antitumor Activity and Pharmacodynamic Studies with the Farnesyl Protein Transferase Inhibitor R115777 in Human Breast Cancer
Lloyd R. Kelland; Vicki Smith; Melanie Valenti; Lisa Patterson; Paul A. Clarke; Simone Detre; Dave End; Angela J. Howes; Mitch Dowsett; Paul Workman; Stephen R. D. Johnston
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Antitumor Efficacy in Vitro and in Vivo of Falconensones, a New Type of Polyene1
Kayoko Tamagawa; Kazuyuki Shimizu; Takuya Ebine; Yoshie Maitani; Tetsuya Fukui; Ken-ichi Kawai; Noriko Takahashi
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Resistance to 2-Chloro-2′-deoxyadenosine of the Human B-cell Leukemia Cell Line EHEB1
Sabine Cardoen; Eric Van Den Neste; Caroline Smal; Jean-François Rosier; Anne Delacauw; Augustin Ferrant; Georges Van den Berghe; Françoise Bontemps
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Anticancer Effect of a Lentiviral Vector Capable of Expressing HIV-1 Vpr
Shen Pang; Mo K. Kang; Sam Kung; Duan Yu; Annie Lee; Betty Poon; Irvin S. Y. Chen; Bob Lindemann; No-Hee Park
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Inhibition of Malignant Cell Growth by 311, a Novel Iron Chelator of the Pyridoxal Isonicotinoyl Hydrazone Class: Effect on the R2 subunit of Ribonucleotide Reductase
Dena A. Green; William E. Antholine; Stuart J. Wong; Des R. Richardson; Christopher R. Chitambar
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DNA Repair Initiated in Chronic Lymphocytic Leukemia Lymphocytes by 4-Hydroperoxycyclophosphamide Is Inhibited by Fludarabine and Clofarabine1
Takahiro Yamauchi; Billie J. Nowak; Michael J. Keating; William Plunkett
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E2F-1 Up-Regulates c-Myc and p14ARF and Induces Apoptosis in Colon Cancer Cells1
Mary Jane Elliott; Yan Bin Dong; Hailiang Yang; Kelly M. McMasters
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Prevention of Human Prostate Tumor Metastasis in Athymic Mice by Antisense Targeting of Human Angiogenin1
Karen A. Olson; H. Randolph Byers; Marc E. Key; James W. Fett
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Tumor Targeting and Imaging of Intraperitoneal Tumors by Use of Antisense Oligo-DNA Complexed with Dendrimers and/or Avidin in Mice1
Noriko Sato; Hisataka Kobayashi; Tsuneo Saga; Yuji Nakamoto; Takayoshi Ishimori; Kaori Togashi; Yasuhisa Fujibayashi; Junji Konishi; Martin W. Brechbiel
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Antisense Anti-MDM2 Oligonucleotides As a Novel Therapeutic Approach to Human Breast Cancer: In Vitro and in Vivo Activities and Mechanisms1
Hui Wang; Li Nan; Dong Yu; Sudhir Agrawal; Ruiwen Zhang
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Systemic Vector Leakage and Transgene Expression by Intratumorally Injected Recombinant Adenovirus Vectors1
Frank Lohr; Qian Huang; Kang Hu; Mark W. Dewhirst; Chuan-Yuan Li
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Bimodal Effects of 1R,2R-Diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on Cell Cycle Checkpoints1
Jian Kuang; Guangan He; Zaifeng Huang; Abdul R. Khokhar; Zahid H. Siddik
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  • Online ISSN 1557-3265
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