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Issues
1 April 2000
ISSN 1078-0432
EISSN 1557-3265
Editorial
Review
Advances in Brief
Universal Inactivation of Both p16 and p15 but not Downstream Components Is an Essential Event in the Pathogenesis of T-Cell Acute Lymphoblastic Leukemia1
Motoko Omura-Minamisawa; Mitchell B. Diccianni; Ayse Batova; Ray C. Chang; Louis J. Bridgeman; John Yu; Jeanette Pullen; W. Paul Bowman; Alice L. Yu
Clinical Trials
A Safety and Pharmacokinetic Study of a Mixed-Backbone Oligonucleotide (GEM231) Targeting the Type I Protein Kinase A by Two-hour Infusions in Patients with Refractory Solid Tumors1
Helen X. Chen; John L. Marshall; Elizabeth Ness; R. Russell Martin; Barry Dvorchik; Naiyer Rizvi; Judith Marquis; Margo McKinlay; William Dahut; Michael J. Hawkins
Phase I Trial of Combined Immunotherapy with Subcutaneous Granulocyte Macrophage Colony-stimulating Factor, Low-Dose Interleukin 2, and Interferon α in Progressive Metastatic Melanoma and Renal Cell Carcinoma
Gijsbert C. de Gast; Heinz-Joseph Klümpen; Florry A. Vyth-Dreese; Marie-José Kersten; Natascha C. V. Verra; Johan Sein; Dian Batchelor; Willem J. Nooijen; Jan H. Schornagel
A Phase I Study of Combination Therapy with Immunotoxins IgG-HD37-Deglycosylated Ricin A Chain (dgA) and IgG-RFB4-dgA (Combotox) in Patients with Refractory CD19(+), CD22(+) B Cell Lymphoma1
Richard A. Messmann; Ellen S. Vitetta; Donna Headlee; Adrian M. Senderowicz; William D. Figg; John Schindler; Dennis F. Michiel; Steven Creekmore; Seth M. Steinberg; David Kohler; Elaine S. Jaffe; Maryalice Stetler-Stevenson; Huachun Chen; Victor Ghetie; Edward A. Sausville
Colorectal Tumors Responding to 5-Fluorouracil Have Low Gene Expression Levels of Dihydropyrimidine Dehydrogenase, Thymidylate Synthase, and Thymidine Phosphorylase1
Dennis Salonga; Kathleen D. Danenberg; Martin Johnson; Ralf Metzger; Susan Groshen; Denice D. Tsao-Wei; Heinz-Josef Lenz; C. Gail Leichman; Lawrence Leichman; Robert B. Diasio; Peter V. Danenberg
Molecular Oncology, Markers, Clinical Correlates
Marked Increase of Trypsin(ogen) in Serum of Linitis Plastica (Gastric Cancer, Borrmann 4) Patients
Yasushi Ichikawa; Naohiko Koshikawa; Satoshi Hasegawa; Takashi Ishikawa; Nobuyoshi Momiyama; Chikara Kunizaki; Masazumi Takahashi; Yoshihiro Moriwaki; Hirotoshi Akiyama; Hiroyuki Yamaoka; Shunsuke Yanoma; Akira Tsuburaya; Yoji Nagashima; Hiroshi Shimada; Kaoru Miyazaki
A Large 6q Deletion Is a Common Cytogenetic Alteration in Fibroadenomas, Pre-malignant Lesions, and Carcinomas of the Breast1
Maria Grazia Tibiletti; Fausto Sessa; Barbara Bernasconi; Roberta Cerutti; Barbara Broggi; Daniela Furlan; Francesco Acquati; Marco Bianchi; Antonella Russo; Carlo Capella; Roberto Taramelli
Detection of Circulating Tumor Cells in Carcinoma Patients by a Novel Epidermal Growth Factor Receptor Reverse Transcription-PCR Assay1
Antonella De Luca; Sandro Pignata; Amelia Casamassimi; Antonio D’Antonio; Cesare Gridelli; Antonio Rossi; Francesco Cremona; Valerio Parisi; Andrea De Matteis; Nicola Normanno
Experimental Therapeutics, Preclinical Pharmacology
High Avidity Melanoma-reactive Cytotoxic T Lymphocytes Are Efficiently Induced from Peripheral Blood Lymphocytes on Stimulation by Peptide-pulsed Melanoma Cells1
Nadine Gervois; Nathalie Labarriere; Soizic Le Guiner; Marie-Christine Pandolfino; Jean-François Fonteneau; Yannik Guilloux; Elisabeth Diez; Brigitte Dreno; Francine Jotereau
Preclinical Toxicity and Efficacy Study of a 14-day Schedule of Oral 5-Iodo-2-pyrimidinone-2′-deoxyribose as a Prodrug for 5-Iodo-2′-deoxyuridine Radiosensitization in U251 Human Glioblastoma Xenografts1
Timothy J. Kinsella; Kathleen A. Vielhuber; Keith A. Kunugi; Jane Schupp; Thomas W. Davis; Howard Sands
Homocamptothecin, an E-Ring-modified Camptothecin, Exerts More Potent Antiproliferative Activity than Other Topoisomerase I Inhibitors in Human Colon Cancers Obtained from Surgery and Maintained in Vitro under Histotypical Culture Conditions1
Patrick Philippart; Luke Harper; Carole Chaboteaux; Christine Decaestecker; Yves Bronckart; Laurence Gordover; Laurence Lesueur-Ginot; Hughes Malonne; Olivier Lavergne; Dennis C. H. Bigg; Pierre Mendes da Costa; Robert Kiss
Identification of Receptor-selective Retinoids That Are Potent Inhibitors of the Growth of Human Head and Neck Squamous Cell Carcinoma Cells1
Shi-Yong Sun; Ping Yue; Li Mao; Marcia I. Dawson; Braham Shroot; William W. Lamph; Richard A. Heyman; Roshantha A. S. Chandraratna; Koichi Shudo; Waun K. Hong; Reuben Lotan
Letters to the Editor
Correspondence re: W. M. Lin et al., Loss of Heterozygosity and Mutational Analysis of the PTEN/MMAC1Gene in Synchronous Endometrial and Ovarian Carcinomas. Clin. Cancer Res., 4: 2577–2583, 1998.
Xavier Matias-Guiu; Elena Bussaglia; Lluis Catasus; Helena Lagarda; Esther Gras; Pilar Machin; Jaime Prat
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