Skip to Main Content

Advertisement

Close

AACR Journals
For Authors
About Us
Article Collections
COVID-19
Webinars

header search

search input Search input auto suggest

Search

Advanced Search

Menu

About
Articles
For Authors
Alerts
News
COVID-19
Webinars

Skip Nav Destination

Issues

Select Year

Issue

Volume 6, Issue 3

1 March 2000

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Special Lecture
Minireview
Advances in Brief
Clinical Trials
Experimental Therapeutics, Preclinical Pharmacology
Molecular Oncology, Markers, Clinical Correlates
Cancer Biology, Immunology, Cytokines
Letters to the Editor

Special Lecture

Blockade of Receptors for Growth Factors: An Anticancer Therapy — The Fourth Annual Joseph H. Burchenal American Association for Cancer Research Clinical Research Award Lecture 1

John Mendelsohn

Minireview

The RB2/p130 Gene: The Latest Weapon in the War against Lung Cancer?1

Pier Paolo Claudio; Mario Caputi; Antonio Giordano

Advances in Brief

Antibody-directed Enzyme Prodrug Therapy: Efficacy and Mechanism of Action in Colorectal Carcinoma 1

M. P. Napier; S. K. Sharma; C. J. Springer; K. D. Bagshawe; A. J. Green; J. Martin; S. M. Stribbling; N. Cushen; D. O’Malley; R. H. J. Begent

Expression of ERCC1 Antisense RNA Abrogates Gemcitabine-mediated Cytotoxic Synergism with Cisplatin in Human Colon Tumor Cells Defective in Mismatch Repair but Proficient in Nucleotide Excision Repair 1

Li-Ying Yang; Lan Li; Hong Jiang; Yu Shen; William Plunkett

The Pathology of Familial Breast Cancer: Histological Features of Cancers in Families Not Attributable to Mutations in BRCA1 or BRCA21

Sunil R. Lakhani; Barry A. Gusterson; Jocelyne Jacquemier; John P. Sloane; Thomas J. Anderson; Marc J. van de Vijver; Deon Venter; Alex Freeman; Antonios Antoniou; Lesley McGuffog; Elizabeth Smyth; C. Michael Steel; Neva Haites; Rodney J. Scott; David Goldgar; Susan Neuhausen; Peter A. Daly; Wilma Ormiston; Ross McManus; Siegfried Scherneck; Bruce A. J. Ponder; P. Andrew Futreal; Julian Peto; Dominique Stoppa-Lyonnet; Yves-Jean Bignon; Jeffery P. Struewing; D. Timothy Bishop; J. G. M. Klijn; Peter Devilee; Cees J. Cornelisse; Christine Lasset; Gilbert Lenoir; Rosa Bjork Barkardottir; Valgardur Egilsson; Ute Hamann; Jenny Chang-Claude; Hagay Sobol; Barbara Weber; Douglas F. Easton; Michael R. Stratton

Differential Expression of E-cadherin and Type IV Collagenase Genes Predicts Outcome in Patients with Stage I Non-Small Cell Lung Carcinoma 1

Roy S. Herbst; Seiji Yano; Hiroki Kuniyasu; Fadlo R. Khuri; Corazon D. Bucana; Fang Guo; Diane Liu; Bonnie Kemp; J. Jack Lee; Waun Ki Hong; Isaiah J. Fidler

Clinical Trials

A Phase I Study of Onyx-015, an E1B Attenuated Adenovirus, Administered Intratumorally to Patients with Recurrent Head and Neck Cancer

Ian Ganly; David Kirn; Susan G. Eckhardt; Gail I. Rodriguez; David S. Soutar; Randol Otto; Andrew G. Robertson; Oirhigh Park; Mark L. Gulley; Carla Heise; Daniel D. Von Hoff; Stanley B. Kaye

Suppression of Telomerase Activity and Cytokine Messenger RNA Levels in Acute Myelogenous Leukemia Cells in Vivo in Patients by Amifostine and Interleukin 4 1

H. D. Preisler; B. Li; J. Yang; R. W. Huang; E. Devemy; P. Venugopal; M. Tao; H. Chopra; S. A. Gregory; S. Adler; S. Sivaraman; P. Toofanfard; A. Jajeh; A. Galvez; E. Robin

Pharmacokinetics of Irinotecan and Its Metabolites SN-38 and APC in Children with Recurrent Solid Tumors after Protracted Low-Dose Irinotecan 1

Margaret K. Ma; William C. Zamboni; Kristine M. Radomski; Wayne L. Furman; Victor M. Santana; Peter J. Houghton; Suzan K. Hanna; Audrey K. Smith; Clinton F. Stewart

Quickly Predicting Chemotherapy Response to Paclitaxel-based Therapy in Non-Small Cell Lung Cancer by Early Technetium-99m Methoxyisobutylisonitrile Chest Single-Photon-Emission Computed Tomography 1

Chia-Hung Kao; Jih-Fang Hsieh; Shih-Chuan Tsai; Yung-Jen Ho; Jong-Kang Lee

Phase II Trial of Bryostatin 1 in Patients with Relapsed Low-Grade Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia 1

Mary L. Varterasian; Ramzi M. Mohammad; Muhammad S. Shurafa; Kim Hulburd; Pamela A. Pemberton; Dorothy H. Rodriguez; Virginia Spadoni; David S. Eilender; Anthony Murgo; Nathan Wall; Maria Dan; Ayad M. Al-Katib

Flow Cytometric Measurement of Intracellular Cytokines Detects Immune Responses in MUC1 Immunotherapy 1

Vaios Karanikas; Jodie Lodding; Vernon C. Maino; Ian F. C. McKenzie

The Development of Biologic End Points in Patients Treated with Differentiation Agents: An Experience of Retinoids in Prostate Cancer 1

W. Kevin Kelly; Iman Osman; Victor E. Reuter; Tracy Curley; Warren D. W. Heston; David M. Nanus; Howard I. Scher

Phase I Trial of All-Trans Retinoic Acid in Patients with Treated Head and Neck Squamous Carcinoma 1

So Hyang Park; William C. Gray; Iris Hernandez; Maria Jacobs; Robert A. Ord; Mohan Sutharalingam; Ruth G. Smith; David A. Van Echo; Suhlan Wu; Barbara A. Conley

A Clinical Study of Hypoxia and Metallothionein Protein Expression in Squamous Cell Carcinomas 1

James A. Raleigh; Shu-Chuan Chou; Dennise P. Calkins-Adams; Cynthia A. Ballenger; Debra B. Novotny; Mahesh A. Varia

Electrochemotherapy with Cisplatin: Clinical Experience in Malignant Melanoma Patients 1

Gregor Serša; Borut Štabuc; Maja Čemažar; Damijan Miklavčič; Zvonimir Rudolf

Phase II Study of Oral Topotecan in Advanced Non-Small Cell Lung Cancer

Shane C. White; Sue Cheeseman; Nicholas Thatcher; Heather Anderson; Bernadette Carrington; Solange Hearn; Graham Ross; Malcolm Ranson

Induction of Antibodies against GM2 Ganglioside by Immunizing Melanoma Patients Using GM2-Keyhole Limpet Hemocyanin + QS21 Vaccine: A Dose-Response Study 1

Paul B. Chapman; D. M. Morrissey; K. S. Panageas; W. B. Hamilton; C. Zhan; A. N. Destro; L. Williams; R. J. Israel; P. O. Livingston

Experimental Therapeutics, Preclinical Pharmacology

In Vivo and in Vitro Ovarian Carcinoma Growth Inhibition by a Phosphatidylinositol 3-Kinase Inhibitor (LY294002)1

Limin Hu; Charles Zaloudek; Gordon B. Mills; Joe Gray; Robert B. Jaffe

Up-Regulation of the Proapoptotic Mediators Bax and Bak after Adenovirus-mediated p53 Gene Transfer in Lung Cancer Cells 1

A. Scott Pearson; Francis R. Spitz; Stephen G. Swisher; Masafumi Kataoka; Mona G. Sarkiss; Raymond E. Meyn; Timothy J. McDonnell; Richard J. Cristiano; Jack A. Roth

Ciprofloxacin Mediated Cell Growth Inhibition, S/G₂-M Cell Cycle Arrest, and Apoptosis in a Human Transitional Cell Carcinoma of the Bladder Cell Line

Olivia Aranha; David P. Wood, Jr.; Fazlul H. Sarkar

The in Vitro Evaluation of 25-Hydroxyvitamin D₃ and 19-nor-1α,25-Dihydroxyvitamin D₂ as Therapeutic Agents for Prostate Cancer 1

Tai C. Chen; Gary G. Schwartz; Kerry L. Burnstein; Bal L. Lokeshwar; Michael F. Holick

Immunoprotective Activities of Multiple Chaperone Proteins Isolated from Murine B-Cell Leukemia/Lymphoma 1

Michael Graner; Amy Raymond; Davis Romney; Lin He; Luke Whitesell; Emmanuel Katsanis

p27^Kip1 Accumulation by Inhibition of Proteasome Function Induces Apoptosis in Oral Squamous Cell Carcinoma Cells 1

Yasusei Kudo; Takashi Takata; Ikuko Ogawa; Toshihiko Kaneda; Sunao Sato; Toshitsugu Takekoshi; Ming Zhao; Mutsumi Miyauchi; Hiromasa Nikai

Flavopiridol, a Cyclin-dependent Kinase Inhibitor, Prevents Spindle Inhibitor-induced Endoreduplication in Human Cancer Cells 1

Monica Motwani; Xiao-kui Li; Gary K. Schwartz

Peroxisome Proliferator-activated Receptor γ as a Novel Target in Cancer Therapy: Binding and Activation by an Aromatic Fatty Acid with Clinical Antitumor Activity 1

Dvorit Samid; Michelle Wells; Marianne E. Greene; Weiyin Shen; Colin N. A. Palmer; Alain Thibault

1-Phenyl-2-decanoylamino-3-morpholino-1-propanol Chemosensitizes Neuroblastoma Cells for Taxol and Vincristine 1

Hannie Sietsma; Robert Jan Veldman; Dorina v. d. Kolk; Bertien Ausema; Willem Nijhof; Willem Kamps; Edo Vellenga; Jan Willem Kok

Colon Cancer Chemopreventive Drugs Modulate Integrin-mediated Signaling Pathways 1

Michael J. Weyant; Adelaide M. Carothers; Maria E. Bertagnolli; Monica M. Bertagnolli

Treatment for Malignant Pleural Effusion of Human Lung Adenocarcinoma by Inhibition of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Phosphorylation 1

Seiji Yano; Roy S. Herbst; Hisashi Shinohara; Barbara Knighton; Corazon D. Bucana; Jerald J. Killion; Jeanette Wood; Isaiah J. Fidler

Macrophage Inflammatory Protein 1α Attenuates the Toxic Effects of Temozolomide in Human Bone Marrow Granulocyte- Macrophage Colony-forming Cells 1

Mark Clemons; Amanda Watson; Anthony Howell; James Chang; Claire Heyworth; Brian Lord; Nidya Testa; T. Michael Dexter; Geoffrey Margison

Therapeutic Synergy of TNP-470 and Ionizing Radiation: Effects on Tumor Growth, Vessel Morphology, and Angiogenesis in Human Glioblastoma Multiforme Xenografts 1

Eva L. Lund; Lone Bastholm; Paul E. G. Kristjansen

A Wild-type Sequence p53 Peptide Presented by HLA-A24 Induces Cytotoxic T Lymphocytes that Recognize Squamous Cell Carcinomas of the Head and Neck 1

Masao Eura; Kazuaki Chikamatsu; Fumihiro Katsura; Atsushi Obata; Yuji Sobao; Masafumi Takiguchi; Yongsheng Song; Ettore Appella; Theresa L. Whiteside; Albert B. DeLeo

Effect of Telomere and Telomerase Interactive Agents on Human Tumor and Normal Cell Lines 1

Sun Young Rha; Elzbieta Izbicka; Richard Lawrence; Karen Davidson; Daekyu Sun; Mary Pat Moyer; G. David Roodman; Lawrence Hurley; Daniel Von Hoff

Pharmacokinetics and Cerebrospinal Fluid Penetration of CI-994 (N-Acetyldinaline) in the Nonhuman Primate 1

Luca Riva; Susan M. Blaney; Robert Dauser; Jed G. Nuchtern; John Durfee; Leticia McGuffey; Stacey L. Berg

Biochemical Correlates of Temozolomide Sensitivity in Pediatric Solid Tumor Xenograft Models 1

David S. Middlemas; Clinton F. Stewart; Mark N Kirstein; Catherine Poquette; Henry S. Friedman; Peter J. Houghton; Thomas P. Brent

Antitumor Activity of N-(2-Hydroxypropyl)methacrylamide Copolymer-Mesochlorin e₆ and Adriamycin Conjugates in Combination Treatments 1

Jane-Guo Shiah; Yongen Sun; C. Matthew Peterson; Richard C. Straight; Jindřich Kopeček

Treatment Regimens Including the Multitargeted Antifolate LY231514 in Human Tumor Xenografts

Beverly A. Teicher; Victor Chen; Chuan Shih; Krishna Menon; Patrick A. Forler; Val G. Phares; Tracy Amsrud

Antisense Suppression of Proline-directed Protein Kinase F_A Enhances Chemosensitivity in Human Prostate Cancer Cells 1

Chuan-Ching Yang; Chih-Ping Hsu; Shiaw-Der Yang

Molecular Oncology, Markers, Clinical Correlates

p53 Mutations in Defined Structural and Functional Domains Are Related to Poor Clinical Outcome in Non-Small Cell Lung Cancer Patients 1

Vidar Skaug; David Ryberg; Elin H. Kure Mohammed O. Arab; Lodve Stangeland; Andreas O. Myking; Aage Haugen

Rapid (“Warm”) Autopsy Study for Procurement of Metastatic Prostate Cancer 1

Mark A. Rubin; Mathew Putzi; Neil Mucci; David C. Smith; Kirk Wojno; Susan Korenchuk; Kenneth J. Pienta

Epstein-Barr Virus DNA in Serum/Plasma as a Tumor Marker for Nasopharyngeal Cancer 1

Kanjana Shotelersuk; Chonlakiat Khorprasert; Sairoong Sakdikul; Wichai Pornthanakasem; Narin Voravud; Apiwat Mutirangura

Prognostic Significance of Cysteine Proteinases Cathepsins B and L and Their Endogenous Inhibitors Stefins A and B in Patients with Squamous Cell Carcinoma of the Head and Neck 1

Primož Strojan; Marjan Budihna; Lojze Šmid; Branka Svetic; Ivan Vrhovec; Janko Kos; Janez Škrk

Prognostic Role of Thymidylate Synthase, Thymidine Phosphorylase/ Platelet-derived Endothelial Cell Growth Factor, and Proliferation Markers in Colorectal Cancer 1

Baukelien van Triest; Herbert M. Pinedo; Johannes L. G. Blaauwgeers; Paul J. van Diest; Pascale S. Schoenmakers; Daphne A. Voorn; Kees Smid; Klaas Hoekman; Henk F. W. Hoitsma; Godefridus J. Peters

DNA-dependent Protein Kinase Activity Correlates with Ku70 Expression and Radiation Sensitivity in Esophageal Cancer Cell Lines 1

Heng-Jiang Zhao; Yoshio Hosoi; Hideo Miyachi; Keiichiro Ishii; Masayuki Yoshida; Kenji Nemoto; Yoshihiro Takai; Shogo Yamada; Norio Suzuki; Tetsuya Ono

Loss of Heterozygosity on Chromosome 6p21.2 as a Potential Marker for Recurrence after Radiotherapy of Human Cervical Cancer 1

Yoko Harima; Keizo Harima; Satoshi Sawada; Yoshimasa Tanaka; Seizaburo Arita; Takeo Ohnishi

Overexpression Level of Stromelysin 3 Is Related to the Lymph Node Involvement in Non-small Cell Lung Cancer 1

Thérèse Janecki Delebecq; Henri Porte; Farid Zerimech; Marie-Christine Copin; Valérie Gouyer; Evelyne Dacquembronne; Malika Balduyck; Alain Wurtz; Guillemette Huet

Pattern of Radiation-induced RET and NTRK1 Rearrangements in 191 Post-Chernobyl Papillary Thyroid Carcinomas: Biological, Phenotypic, and Clinical Implications 1

Hartmut M. Rabes; Evgenij P. Demidchik; Juri D. Sidorow; Edmund Lengfelder; Claudia Beimfohr; Dieter Hoelzel; Sabine Klugbauer

Disease Control of Uterine Cervical Cancer: Relationships to Tumor Oxygen Tension, Vascular Density, Cell Density, and Frequency of Mitosis and Apoptosis Measured before Treatment and during Radiotherapy 1

Heidi Lyng; Kolbein Sundfør; Claes Tropé; Einar K. Rofstad

Expression of Cell Cycle Control Proteins in Primary Colorectal Tumors Does Not Always Predict Expression in Lymph Node Metastases 1

Judith A. McKay; Joy J. Douglas; Val G. Ross; Stephanie Curran; Fareeda Y. Ahmed; Joseph F. Loane; Graeme I. Murray; Howard L. McLeod

Microsatellite Alterations in Plasma DNA of Primary Breast Cancer Patients 1

Jacqueline A. Shaw; Brendan M. Smith; Tom Walsh; Suzanne Johnson; Lindsay Primrose; Martin J. Slade; Rosemary A. Walker; R. Charles Coombes

Predictive Survival Markers in Patients with Surgically Resected Non-Small Cell Lung Carcinoma 1

Judith Moldvay; Philippe Scheid; Pascal Wild; Karim Nabil; Joëlle Siat; Jacques Borrelly; Béatrice Marie; Guillaume Farré; Taoufik Labib; Gérard Pottier; Richard Sesboüé; Christian Bronner; Jean-Michel Vignaud; Yves Martinet; Nadine Martinet

Elevated Levels of p66 Shc Are Found in Breast Cancer Cell Lines and Primary Tumors with High Metastatic Potential 1

James G. Jackson; Toshiyuki Yoneda; Gary M. Clark; Douglas Yee

Differential Expression of Osteonectin/SPARC during Human Prostate Cancer Progression 1

Regi Thomas; Lawrence D. True; James A. Bassuk; Paul H. Lange; Robert L. Vessella

Prognostic Factors in Hodgkin’s Disease: Multivariate Analysis of 327 Patients from a Single Institution

Piotr Smolewski; Tadeusz Robak; Euzebiusz Krykowski; Maria Blasiñska-Morawiec; Hanna Niewiadomska; Anna Pluzanska; Ewa Chmielowska; Oscar Zambrano

Vascular Endothelial Growth Factor Expression Predicts Outcome and Lymph Node Metastasis in Squamous Cell Carcinoma of the Esophagus 1

Chih-Horng Shih; Soji Ozawa; Nobutoshi Ando; Masakazu Ueda; Masaki Kitajima

Clinical Significance of Matrix Metalloproteinase-7 Expression in Esophageal Carcinoma

Keishi Yamashita; Masaki Mori; Takeshi Shiraishi; Kenji Shibuta; Keizo Sugimachi

Clinical Significance of Serum Soluble Intercellular Adhesion Molecule 1 in Gastric Cancer

Bunzo Nakata; Takeshi Hori; Takeshi Sunami; Yoshinari Ogawa; Masakazu Yashiro; Kiyoshi Maeda; Tetsuji Sawada; Yasuyuki Kato; Tetsuro Ishikawa; Kosei Hirakawa

Cancer Biology, Immunology, Cytokines

Characterization of Signaling Cascades Triggered by Human Interleukin-6 versus Kaposi’s Sarcoma-associated Herpes Virus-encoded Viral Interleukin 6 1

Teru Hideshima; Dharminder Chauhan; Gerrard Teoh; Noopur Raje; Steven P. Treon; Yu-Tzu Tai; Yoshihito Shima; Kenneth C. Anderson

TabBO: A Model Reflecting Common Molecular Features of Androgen-independent Prostate Cancer 1

Nora M. Navone; Maria del C. Rodriguez-Vargas; William F. Benedict; Patricia Troncoso; Timothy J. McDonnell; Jaim-Hua Zhou; Rajyalakshmi Luthra; Christopher J. Logothetis

Letters to the Editor

Letters to the Editor

Wojciech Feleszko

Advertisement

Email alerts

Online First Alert

eTOC Alert

Latest
Most Read
Most Cited

[18F]FDG and [18F]FES PET/CT Imaging as a Biomarker for Therapy Effect in Patients with Metastatic ER+ Breast Cancer Undergoing Treatment with Rintodestrant

Characterization of Cell-free DNA Size Distribution in Osteosarcoma Patients

Single-cell transcriptomics reveals immune reconstitution in R/R T-ALL/LBL patients with donor-derived CD7 CAR-T therapy

The oral PI3Kδ inhibitor linperlisib for the treatment of relapsed and/or refractory follicular lymphoma: A phase 2, single-arm, open-label clinical trial

Issues
Online First
Collections

News
Twitter

Online ISSN 1557-3265
Print ISSN 1078-0432

AACR Journals

Blood Cancer Discovery
Cancer Discovery
Cancer Epidemiology, Biomarkers, & Prevention
Cancer Immunology Research
Cancer Prevention Research
Cancer Research
Cancer Research Communications
Clinical Cancer Research
Molecular Cancer Research
Molecular Cancer Therapeutics

Info for Advertisers
Info for Librarians
Privacy Policy

Twitter
LinkedIn
Facebook
Youtube

Copyright © 2022 by the American Association for Cancer Research.

This Feature Is Available To Subscribers Only

Sign In or Create an Account

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.

Accept