Skip Nav Destination

Issues

Select Year

Issue

Volume 5, Issue 2

1 February 1999

All Issues

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Review
Advances in Brief
Clinical Trials
Molecular Oncology, Markers, Clinical Correlates
Experimental Therapeutics
Cancer Biology, Immunology, Cytokines
Meeting Report
Letters to the Editor
Errata

Review

Colorectal Cancer as a Model for Immunotherapy

Kenneth A. Foon; John Yannelli; Malaya Bhattacharya-Chatterjee

Extract

View articletitled, Colorectal Cancer as a Model for Immunotherapy

Open the PDF for in another window

Advances in Brief

SPARC: A Potential Diagnostic Marker of Invasive Meningiomas 1

Sandra A. Rempel; Shugang Ge; Jorge A. Gutiérrez

Abstract

View articletitled, SPARC: A Potential Diagnostic Marker of Invasive Meningiomas<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Alterations of Rb Pathway (Rb-p16^INK4-Cyclin D1) in Preinvasive Bronchial Lesions 1

Elisabeth Brambilla; Sylvie Gazzeri; Denis Moro; Sylvie Lantuejoul; Sylvie Veyrenc; Christian Brambilla

Abstract

View articletitled, Alterations of Rb Pathway (Rb-p16INK4-Cyclin D1) in Preinvasive Bronchial Lesions<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Increased Activator Protein-1 DNA Binding and c-Jun NH₂-Terminal Kinase Activity in Human Breast Tumors with Acquired Tamoxifen Resistance 1

Stephen R. D. Johnston; Biao Lu; Gary K. Scott; Peter J. Kushner; Ian E. Smith; Mitchell Dowsett; Christopher C. Benz

Abstract

View articletitled, Increased Activator Protein-1 DNA Binding and c-Jun NH2-Terminal Kinase Activity in Human Breast Tumors with Acquired Tamoxifen Resistance<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Anti-epidermal Growth Factor Receptor Antibody C225 Inhibits Angiogenesis in Human Transitional Cell Carcinoma Growing Orthotopically in Nude Mice 1

Paul Perrotte; Takashi Matsumoto; Keiji Inoue; Hiroki Kuniyasu; Beryl Y. Eve; Daniel J. Hicklin; Robert Radinsky; Colin P. N. Dinney

Abstract

View articletitled, Anti-epidermal Growth Factor Receptor Antibody C225 Inhibits Angiogenesis in Human Transitional Cell Carcinoma Growing Orthotopically in Nude Mice<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Persistent Induction of Apoptosis and Suppression of Mitosis as the Basis for Curative Therapy with S-1, an Oral 5-Fluorouracil Prodrug in a Colorectal Tumor Model 1

Shousong Cao; Kun Lu; Karoly Tóth; Harry K. Slocum; Tetsuhiko Shirasaka; Youcef M. Rustum

Abstract

View articletitled, Persistent Induction of Apoptosis and Suppression of Mitosis as the Basis for Curative Therapy with S-1, an Oral 5-Fluorouracil Prodrug in a Colorectal Tumor Model<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Clinical Trials

Phase I Study of Escalating Doses of Edatrexate in Combination with Paclitaxel in Patients with Metastatic Breast Cancer

Gabriella D’Andrea; David Fennelly; Larry Norton; Jose Baselga; Teresa Gilewski; Clifford Hudis; Mary Ellen Moynahan; George Raptis; Nancy Sklarin; Antonella Surbone; Maria Theodoulou; Mary Agnes Templeton; Tzy-Jyun Yao; Andrew D. Seidman

Abstract

View articletitled, Phase I Study of Escalating Doses of Edatrexate in Combination with Paclitaxel in Patients with Metastatic Breast Cancer

Open the PDF for in another window

Distinct Clinical and Laboratory Activity of Two Recombinant Interleukin-2 Preparations 1

Jacquelyn A. Hank; Jean Surfus; Jacek Gan; Mark Albertini; Mary Lindstrom; Joan H. Schiller; Kirsten M. Hotton; Masoud Khorsand; Paul M. Sondel

Abstract

View articletitled, Distinct Clinical and Laboratory Activity of Two Recombinant Interleukin-2 Preparations<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Phase I Study of Eniluracil, a Dihydropyrimidine Dehydrogenase Inactivator, and Oral 5-Fluorouracil with Radiation Therapy in Patients with Recurrent or Advanced Head and Neck Cancer 1

Rod A. Humerickhouse; M. Eileen Dolan; Daniel J. Haraf; Bruce Brockstein; Kerstin Stenson; Merrill Kies; Laura Sulzen; Mark J. Ratain; Everett E. Vokes

Abstract

View articletitled, Phase I Study of Eniluracil, a Dihydropyrimidine Dehydrogenase Inactivator, and Oral 5-Fluorouracil with Radiation Therapy in Patients with Recurrent or Advanced Head and Neck Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

A Phase I and Pharmacokinetic Study of Losoxantrone and Paclitaxel in Patients with Advanced Solid Tumors 1

Sami G. Diab; Sharyn D. Baker; Amita Joshi; Howard A. Burris; Patrick W. Cobb; Miguel A. Villalona-Calero; S. Gail Eckhardt; Geoffrey R. Weiss; Gladys I. Rodriguez; Ronald Drengler; Maura Kraynak; Lisa Hammond; Michael Finizio; Daniel D. Von Hoff; Eric K. Rowinsky

Abstract

View articletitled, A Phase I and Pharmacokinetic Study of Losoxantrone and Paclitaxel in Patients with Advanced Solid Tumors<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Absorption, Metabolism, and Excretion of ¹⁴C-Temozolomide following Oral Administration to Patients with Advanced Cancer 1

Sharyn D. Baker; Mark Wirth; Paul Statkevich; Pascale Reidenberg; Kevin Alton; Susan E. Sartorius; Margaret Dugan; David Cutler; Vijay Batra; Louise B. Grochow; Ross C. Donehower; Eric K. Rowinsky

Abstract

View articletitled, Absorption, Metabolism, and Excretion of 14C-Temozolomide following Oral Administration to Patients with Advanced Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Molecular Oncology, Markers, Clinical Correlates

Apoptosis during Breast Carcinoma Progression 1

Merja Vakkala; Kimmo Lähteenmäki; Hannu Raunio; Paavo Pääkkö; Ylermi Soini

Abstract

View articletitled, Apoptosis during Breast Carcinoma Progression<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Colorectal Liver Metastasis Thymidylate Synthase Staining Correlates with Response to Hepatic Arterial Floxuridine

Michael M. Davies; Patrick G. Johnston; Suki Kaur; Timothy G. Allen-Mersh

Abstract

View articletitled, Colorectal Liver Metastasis Thymidylate Synthase Staining Correlates with Response to Hepatic Arterial Floxuridine

Open the PDF for in another window

Clinical Significance of Decreased ζ Chain Expression in Peripheral Blood Lymphocytes of Patients with Head and Neck Cancer 1

Iris Kuss; Takao Saito; Jonas T. Johnson; Theresa L. Whiteside

Abstract

View articletitled, Clinical Significance of Decreased ζ Chain Expression in Peripheral Blood Lymphocytes of Patients with Head and Neck Cancer<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Expression of MAGE and GAGE in High-Grade Brain Tumors: A Potential Target for Specific Immunotherapy and Diagnostic Markers 1

Deborah L. Scarcella; C. W. Chow; Michael F. Gonzales; Catherine Economou; Francis Brasseur; David M. Ashley

Abstract

View articletitled, Expression of MAGE and GAGE in High-Grade Brain Tumors: A Potential Target for Specific Immunotherapy and Diagnostic Markers<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Experimental Therapeutics

Tyrosine Kinase Inhibitor Emodin Suppresses Growth of HER-2/neu-overexpressing Breast Cancer Cells in Athymic Mice and Sensitizes These Cells to the Inhibitory Effect of Paclitaxel 1

Lisha Zhang; Yiu-Keung Lau; Weiya Xia; Gabriel N. Hortobagyi; Mien-Chie Hung

Abstract

View articletitled, Tyrosine Kinase Inhibitor Emodin Suppresses Growth of HER-2/neu-overexpressing Breast Cancer Cells in Athymic Mice and Sensitizes These Cells to the Inhibitory Effect of Paclitaxel<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

A Requirement for Protein Kinase C Inhibition for Calcium-triggered Apoptosis in Acute Lymphoblastic Leukemia Cells 1

De-Min Zhu; Wei-Hua Fang; Rama Krishna Narla; Fatih M. Uckun

Abstract

View articletitled, A Requirement for Protein Kinase C Inhibition for Calcium-triggered Apoptosis in Acute Lymphoblastic Leukemia Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Expression of Apoptosis-related Genes in Human Head and Neck Squamous Cell Carcinomas Undergoing p53-mediated Programmed Cell Death 1

Mitchell J. Frederick; Paula R. Holton; Mike Hudson; Mary Wang; Gary L. Clayman

Abstract

View articletitled, Expression of Apoptosis-related Genes in Human Head and Neck Squamous Cell Carcinomas Undergoing p53-mediated Programmed Cell Death<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Induction of Lasting Complete Regression of Preformed Distinct Solid Tumors by Targeting the Tumor Vasculature Using Two New Anti-Endoglin Monoclonal Antibodies 1

Fumihiko Matsuno; Yuro Haruta; Masao Kondo; Hilda Tsai; Maurice Barcos; Ben K. Seon

Abstract

View articletitled, Induction of Lasting Complete Regression of Preformed Distinct Solid Tumors by Targeting the Tumor Vasculature Using Two New Anti-Endoglin Monoclonal Antibodies<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

In Vivo Localization of [¹¹¹In]-DTPA-d-Phe 1-Octreotide to Human Ovarian Tumor Xenografts Induced to Express the Somatostatin Receptor Subtype 2 Using an Adenoviral Vector¹

Buck E. Rogers; Stephanie F. McLean; Richard L. Kirkman; Debbie Della Manna; Sheila J. Bright; Christine C. Olsen; Angela D. Myracle; Matthew S. Mayo; David T. Curiel; Donald J. Buchsbaum

Abstract

View articletitled, In Vivo Localization of [111In]-DTPA-d-Phe<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>-Octreotide to Human Ovarian Tumor Xenografts Induced to Express the Somatostatin Receptor Subtype 2 Using an Adenoviral Vector<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Progestins Inhibit the Growth of MDA-MB-231 Cells Transfected with Progesterone Receptor Complementary DNA 1

Valerie C-L. Lin; Eng Hen Ng; Swee Eng Aw; Michelle G-K. Tan; Esther H-L. Ng; Vivian S-W. Chan; Gay Hui Ho

Abstract

View articletitled, Progestins Inhibit the Growth of MDA-MB-231 Cells Transfected with Progesterone Receptor Complementary DNA<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells 1

Joseph N. Contessa; Dean B. Reardon; Daniel Todd; Paul Dent; Ross B. Mikkelsen; Kristoffer Valerie; Geoffrey D. Bowers; Rupert K. Schmidt-Ullrich

Abstract

View articletitled, The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Combination of Theanine with Doxorubicin Inhibits Hepatic Metastasis of M5076 Ovarian Sarcoma 1

Tomomi Sugiyama; Yasuyuki Sadzuka

Abstract

View articletitled, Combination of Theanine with Doxorubicin Inhibits Hepatic Metastasis of M5076 Ovarian Sarcoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Combination Interferon-α2a and 13-cis-Retinoic Acid Enhances Radiosensitization of Human Malignant Glioma Cells in Vitro1

Colin Malone; Patric M. Schiltz; Shankar K. Nayak; Michael W. Shea; Robert O. Dillman

Abstract

View articletitled, Combination Interferon-α2a and 13-cis-Retinoic Acid Enhances Radiosensitization of Human Malignant Glioma Cells in Vitro<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

A Fas-dependent Component in 5-Fluorouracil/Leucovorin-induced Cytotoxicity in Colon Carcinoma Cells 1

David M. Tillman; Istvan Petak; Janet A. Houghton

Abstract

View articletitled, A Fas-dependent Component in 5-Fluorouracil/Leucovorin-induced Cytotoxicity in Colon Carcinoma Cells<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Differential Responses of Normal, Premalignant, and Malignant Human Bronchial Epithelial Cells to Receptor-selective Retinoids 1

Shi-Yong Sun; Jonathan M. Kurie; Ping Yue; Marcia I. Dawson; Braham Shroot; Roshantna A. S. Chandraratna; Waun K. Hong; Reuben Lotan

Abstract

View articletitled, Differential Responses of Normal, Premalignant, and Malignant Human Bronchial Epithelial Cells to Receptor-selective Retinoids<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Increased Sensitivity of Hydroxyurea-resistant Leukemic Cells to Gemcitabine 1

Stuart J. Wong; Michael S. Myette; Janine P. Wereley; Christopher R. Chitambar

Abstract

View articletitled, Increased Sensitivity of Hydroxyurea-resistant Leukemic Cells to Gemcitabine<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Presentation of Renal Tumor Antigens by Human Dendritic Cells Activates Tumor-infiltrating Lymphocytes against Autologous Tumor: Implications for Live Kidney Cancer Vaccines 1

Peter Mulders; Cho-Lea Tso; Barbara Gitlitz; Randhir Kaboo; Andreas Hinkel; Stacey Frand; Sylvia Kiertscher; Michael D. Roth; Jean deKernion; Robert Figlin; Arie Belldegrun

Abstract

View articletitled, Presentation of Renal Tumor Antigens by Human Dendritic Cells Activates Tumor-infiltrating Lymphocytes against Autologous Tumor: Implications for Live Kidney Cancer Vaccines<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Cancer Biology, Immunology, Cytokines

Coexpression of Transcripts Encoding EPHB Receptor Protein Tyrosine Kinases and Their Ephrin-B Ligands in Human Small Cell Lung Carcinoma 1

Xao X. Tang; Garrett M. Brodeur; Barbara G. Campling; Naohiko Ikegaki

Abstract

View articletitled, Coexpression of Transcripts Encoding EPHB Receptor Protein Tyrosine Kinases and Their Ephrin-B Ligands in Human Small Cell Lung Carcinoma<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Expanded Tumor-reactive CD4⁺ T-Cell Responses to Human Cancers Induced by Secondary Anti-CD3/Anti-CD28 Activation 1

Qiao Li; Senta A. Furman; Carol R. Bradford; Alfred E. Chang

Abstract

View articletitled, Expanded Tumor-reactive CD4+ T-Cell Responses to Human Cancers Induced by Secondary Anti-CD3/Anti-CD28 Activation<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Meeting Report

Gene Therapy and Translational Cancer Research 1

Chi V. Dang; Stanton L. Gerson; Marcia Litwak; Martin Padarathsingh

Extract

View articletitled, Gene Therapy and Translational Cancer Research<a href="javascript:;" reveal-id="FN1" data-open="FN1" class="link link-ref link-reveal xref-fn js-xref-fn split-view-modal">1</a>

Open the PDF for in another window

Letters to the Editor

Correspondence re: V. I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Cancer Res., 4: 45–52, 1998.: Fludarabine: Phosphate or No Phosphate, That Is the Confusion Letter

Andrew G. Bosanquet

Extract

View articletitled, Correspondence re: V. I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Cancer Res., 4: 45–52, 1998.: Fludarabine: Phosphate or No Phosphate, That Is the Confusion Letter

Open the PDF for in another window

Errata

B. Melichar et al. 4: 3069–3076, 1998

Extract

View articletitled, B. Melichar et al. 4: 3069–3076, 1998

Open the PDF for in another window

Email alerts

Online First Alert

eTOC Alert

Issues

Review

Advances in Brief

Clinical Trials

Molecular Oncology, Markers, Clinical Correlates

Experimental Therapeutics

In Vivo Localization of [111In]-DTPA-d-Phe1-Octreotide to Human Ovarian Tumor Xenografts Induced to Express the Somatostatin Receptor Subtype 2 Using an Adenoviral Vector1

Cancer Biology, Immunology, Cytokines

Meeting Report

Letters to the Editor

Errata

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only

In Vivo Localization of [¹¹¹In]-DTPA-d-Phe 1-Octreotide to Human Ovarian Tumor Xenografts Induced to Express the Somatostatin Receptor Subtype 2 Using an Adenoviral Vector¹