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Volume 4, Issue 9

1 September 1998

Front Matter
Table of Contents
Back Matter
Editorial Board

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Hypothesis
Advances in Brief
Research Articles

Hypothesis

The relationship between high-dose treatment and combination chemotherapy: the concept of summation dose intensity.

E Frei, 3rd; A Elias; C Wheeler; P Richardson; W Hryniuk

Advances in Brief

Clinical impact of pharmacokinetically-guided dose adaptation of 5-fluorouracil: results from a multicentric randomized trial in patients with locally advanced head and neck carcinomas.

R Fety; F Rolland; M Barberi-Heyob; A Hardouin; L Campion; T Conroy; J L Merlin; A Rivière; G Perrocheau; M C Etienne; G Milano

Immunocytochemical detection of somatostatin receptors sst1, sst2A, sst2B, and sst3 in paraffin-embedded breast cancer tissue using subtype-specific antibodies.

S Schulz; J Schmitt; D Wiborny; H Schmidt; S Olbricht; W Weise; A Roessner; C Gramsch; V Höllt

Prevention of intestinal toxic effects and intensification of irinotecan's therapeutic efficacy against murine colon cancer liver metastases by oral administration of the lipopeptide JBT 3002.

H Shinohara; J J Killion; H Kuniyasu; R Kumar; I J Fidler

Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors.

D Siegel; W A Franklin; D Ross

The effects of local hyperthermia on the catabolism of a radioiodinated chimeric monoclonal antibody.

M L Hauck; M R Zalutsky

Research Articles

Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue.

P H Walz; P Björk; P O Gunnarsson; K Edman; B Hartley-Asp

Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N1-(2'-tetrahydrofuryl)-5-fluorouracil.

D H Ho; R Pazdur; W Covington; N Brown; Y Y Huo; Y Lassere; J Kuritani

In vivo inhibition of aromatization by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients.

J Geisler; N King; G Anker; G Ornati; E Di Salle; P E Lønning; M Dowsett

Phase I study of a five-day dose schedule of 4-Ipomeanol in patients with non-small cell lung cancer.

V K Kasturi; M P Dearing; S C Piscitelli; E K Russell; G G Sladek; K O'Neil; G A Turner; T L Morton; M C Christian; B E Johnson; M J Kelley

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7.

M A Steller; K J Gurski; M Murakami; R W Daniel; K V Shah; E Celis; A Sette; E L Trimble; R C Park; F M Marincola

Phase I study of the duocarmycin semisynthetic derivative KW-2189 given daily for five days every six weeks.

S R Alberts; C Erlichman; J M Reid; J A Sloan; M M Ames; R L Richardson; R M Goldberg

Effect of neoadjuvant androgen deprivation on circulating prostate cells in the bone marrow of men undergoing radical prostatectomy.

D P Wood, Jr; A Beaman; M Banerjee; I Powell; E Pontes; M L Cher

Changes in folate status as determined by reduction in total plasma homocysteine levels during leucovorin modulation of 5-fluorouracil therapy in cancer patients.

J Geisler; S B Geisler; P E Lønning; R Smaaland; K M Tveit; H Refsum; P M Ueland

Tumor angiogenesis and micrometastasis in bone marrow of patients with early gastric cancer.

Y Maehara; S Hasuda; T Abe; E Oki; Y Kakeji; S Ohno; K Sugimachi

Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma.

K Kramer; W L Gerald; B H Kushner; S M Larson; M Hameed; N K Cheung

Limitations of the reverse transcription-polymerase chain reaction method for the detection of carcinoembryonic antigen-positive tumor cells in peripheral blood.

Y Ko; M Klinz; G Totzke; I Gouni-Berthold; A Sachinidis; H Vetter

Circulating p53 antibodies as early markers of oral cancer: correlation with p53 alterations.

R Ralhan; N Nath; S Agarwal; M Mathur; B Wasylyk; N K Shukla

Specific transcription factors prognostic for prostate cancer progression.

K Aoyagi; I Shima; M Wang; Y Hu; F U Garcia; M E Stearns

Angiogenin expression and prognosis in primary breast carcinoma.

S Montero; C Guzmán; H Cortés-Funes; R Colomer

Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.

L Zhang; J W Taub; M Williamson; S C Wong; B Hukku; J Pullen; Y Ravindranath; L H Matherly

Augmented membrane type 1 matrix metalloproteinase (MT1-MMP):MMP-2 messenger RNA ratio in gastric carcinomas with poor prognosis.

C Caenazzo; M Onisto; L Sartor; R Scalerta; A Giraldo; D Nitti; S Garbisa

Expression profile of prostate-specific antigen messenger RNA assessed by in situ hybridization is a novel prognostic marker for patients with untreated prostate cancer.

T Tsurusaki; T Koji; H Sakai; H Kanetake; Y Saito

Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas.

Y Kitadai; K Haruma; T Tokutomi; S Tanaka; K Sumii; M Carvalho; M Kuwabara; K Yoshida; T Hirai; G Kajiyama; E Tahara

UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner.

C T Hsueh; D Kelsen; G K Schwartz

Photodynamic therapy of naturally occurring tumors in animals using a novel benzophenothiazine photosensitizer.

A E Frimberger; A S Moore; L Cincotta; S M Cotter; J W Foley

Interferon-alpha-induced activation of signal transducer and activator of transcription proteins in malignant melanoma.

W E Carson

Desensitization and sensitization of cells to fluoropyrimidines with different antisenses directed against thymidylate synthase messenger RNA.

J Ju; S E Kane; H J Lenz; K D Danenberg; E Chu; P V Danenberg

Characterization of a novel bispecific antibody that mediates Fcgamma receptor type I-dependent killing of tumor-associated glycoprotein-72-expressing tumor cells.

C Russoniello; C Somasundaram; J Schlom; Y M Deo; T Keler

Functionality of the progesterone receptor in ovarian cancer and its regulation by estrogen.

S P Langdon; H Gabra; J M Bartlett; G J Rabiaz; R A Hawkins; A L Tesdale; A A Ritchie; W R Miller; J F Smyth

Toxicity and dose-response studies of 1,25-(OH)2-16-ene-23-yne vitamin D3 in transgenic mice.

C L Wilkerson; S R Darjatmoko; M J Lindstrom; D M Albert

Antimestatic and antitumor activities of interleukin 10 in transfected human prostate PC-3 ML clones: Orthotopic growth in severe combined immunodeficient mice.

M E Stearns; M Wang

Combination E2F-1 and p53 gene transfer does not enhance growth inhibition in human squamous cell carcinoma of the head and neck.

D K Frank; T J Liu; M J Frederick; G L Clayman

Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human osteosarcoma.

Y Oda; A Sakamoto; N Shinohara; T Ohga; T Uchiumi; K Kohno; M Tsuneyoshi; M Kuwano; Y Iwamoto

Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung.

S R Wright; A H Boag; G Valdimarsson; D R Hipfner; B G Campling; S P Cole; R G Deeley

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