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Volume 4, Issue 4

1 April 1998

Front Matter
Table of Contents
Back Matter
Editorial Board

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Minireview
Advances in Brief
Research Articles

Minireview

Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications.

F Ciardiello; G Tortora

Advances in Brief

p53 and RB expression predict progression in T1 bladder cancer.

H B Grossman; M Liebert; M Antelo; C P Dinney; S X Hu; J L Palmer; W F Benedict

Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.

L L Nielsen; P Lipari; J Dell; M Gurnani; G Hajian

Research Articles

Cyclin D1 protein is overexpressed in hyperplasia and intraductal carcinoma of the breast.

K M Alle; S M Henshall; A S Field; R L Sutherland

Quantitative analysis of carcinoembryonic antigen messenger RNA in peripheral venous blood and portal blood of patients with pancreatic ductal adenocarcinoma.

N O Funaki; J Tanaka; R Hosotani; M Kogire; H Suwa; M Imamura

Philadelphia chromosome-positive myeloid cells in the peripheral blood of chronic myelogenous leukemia patients: comparison with the frequency detected in cycling cells of the bone marrow.

D Seong; P Thall; H M Kantarjian; M Talpaz; J Swantkowski; J Xu; Y Shen; A Glassman; L Ramagli; M J Siciliano

Expression of the plasminogen activation system in kidney cancer correlates with its aggressive phenotype.

R Swiercz; J D Wolfe; A Zaher; J Jankun

Analysis of colorectal cancer by comparative genomic hybridization: evidence for induction of the metastatic phenotype by loss of tumor suppressor genes.

A Paredes-Zaglul; J J Kang; Y P Essig; W Mao; R Irby; M Wloch; T J Yeatman

An orthotopic model of human pancreatic cancer in severe combined immunodeficient mice: potential application for preclinical studies.

R M Mohammad; A Al-Katib; G R Pettit; V K Vaitkevicius; U Joshi; V Adsay; A P Majumdar; F H Sarkar

Preclinical antitumor activity of an antibody against the leukocyte antigen CD48.

H Sun; B J Norris; K Atkinson; J C Biggs; G M Smith

Cytotoxic activity of epidermal growth factor-genistein against breast cancer cells.

F M Uckun; R K Narla; X Jun; T Zeren; T Venkatachalam; K G Waddick; A Rostostev; D E Myers

Intracellular coexpression of epidermal growth factor receptor, Her-2/neu, and p21ras in human breast cancers: evidence for the existence of distinctive patterns of genetic evolution that are common to tumors from different patients.

S E Shackney; A A Pollice; C A Smith; L E Janocko; L Sweeney; K A Brown; S G Singh; L Gu; R Yakulis; J F Lucke

Phase II and pharmacodynamic studies of pyrazine diazohydroxide (NSC 361456) in patients with advanced renal and colorectal cancer.

N J Vogelzang; S Mani; R L Schilsky; R H Ansari; D Taber; S N Rhinehart; J C Garcia; S C Meyer; R Mick; B E Brockstein; W M Stadler; M J Ratain; E E Vokes

Prospective randomized trial of 5-fluorouracil versus 5-fluorouracil plus levamisole in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial.

M T Bandealy; R Gonin; P J Loehrer; F Monaco; L H Einhorn

Effect of food on the pharmacokinetics of capecitabine and its metabolites following oral administration in cancer patients.

B Reigner; J Verweij; L Dirix; J Cassidy; C Twelves; D Allman; E Weidekamm; B Roos; L Banken; M Utoh; B Osterwalder

Dynamic T1-weighted magnetic resonance imaging and positron emission tomography in patients with lung cancer: correlating vascular physiology with glucose metabolism.

G J Hunter; L M Hamberg; N Choi; R K Jain; T McCloud; A J Fischman

Idiotypic protein-pulsed adherent peripheral blood mononuclear cell-derived dendritic cells prime immune system in multiple myeloma.

Y J Wen; M Ling; R Bailey-Wood; S H Lim

Elevated levels of versican but not decorin predict disease progression in early-stage prostate cancer.

C Ricciardelli; K Mayne; P J Sykes; W A Raymond; K McCaul; V R Marshall; D J Horsfall

Loss of heterozygosity on chromosome 18q in cohesive-type gastric cancer is associated with tumor progression and poor prognosis.

T Inoue; S Uchino; N Shiraishi; Y Adachi; S Kitano

Presence of human papilloma virus DNA in pelvic lymph nodes can predict unexpected recurrence of cervical cancer in patients with histologically negative lymph nodes.

Y Kobayashi; M Yoshinouchi; G Tianqi; K Nakamura; A Hongo; S Kamimura; Y Mizutani; J Kodama; Y Miyagi; T Kudo

Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts.

R Giavazzi; A Garofalo; C Ferri; V Lucchini; E A Bone; S Chiari; P D Brown; M I Nicoletti; G Taraboletti

Recombinant heregulin-Pseudomonas exotoxin fusion proteins: interactions with the heregulin receptors and antitumor activity in vivo.

D Yang; C T Kuan; J Payne; A Kihara; A Murray; L M Wang; M Alimandi; J H Pierce; I Pastan; M E Lippman

Induction of sensitivity to doxorubicin and etoposide by transfection of MCF-7 breast cancer cells with heregulin beta-2.

L N Harris; L Yang; C Tang; D Yang; R Lupu

Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts.

N Sawada; T Ishikawa; Y Fukase; M Nishida; T Yoshikubo; H Ishitsuka

Activity of oxaliplatin against human tumor colony-forming units.

E Raymond; R Lawrence; E Izbicka; S Faivre; D D Von Hoff

Impairment of the actin-myosin interaction in permeabilized cardiac trabeculae after chronic doxorubicin treatment.

A E Bottone; E E Voest; E L de Beer

Interleukin 6 differentially potentiates the antitumor effects of taxol and vinblastine in U266 human myeloma cells.

M Aoyama; D MacIsaac; R M Bukowski; M K Ganapathi

Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment.

S Fan; B Cherney; W Reinhold; K Rucker; P M O'Connor

Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins.

X Zi; D K Feyes; R Agarwal

Infrequent mutation of the p16/MTS1 gene and overexpression of cyclin-dependent kinase 4 in human primary soft-tissue sarcoma.

J Yao; R E Pollock; A Lang; M Tan; P W Pisters; D Goodrich; A El-Naggar; D Yu

The BAX gene, the promoter of apoptosis, is mutated in genetically unstable cancers of the colorectum, stomach, and endometrium.

H Ouyang; T Furukawa; T Abe; Y Kato; A Horii

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The oral PI3Kδ inhibitor linperlisib for the treatment of relapsed and/or refractory follicular lymphoma: A phase 2, single-arm, open-label clinical trial

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