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Volume 4, Issue 3

1 March 1998

Front Matter
Table of Contents
Back Matter
Editorial Board

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Review
Advances in Brief
Research Articles

Review

Update on endocrine therapy for breast cancer.

A U Buzdar; G Hortobagyi

Advances in Brief

Telomerase: a potential marker of bladder transitional cell carcinoma in bladder washes.

D H Lee; S C Yang; S J Hong; B H Chung; I Y Kim

Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer.

V A Papadimitrakopoulou; Y Oh; A El-Naggar; J Izzo; G Clayman; L Mao

Pharmacodynamics of topoisomerase I inhibition: Western blot determination of topoisomerase I and cleavable complex in patients with upper gastrointestinal malignancies treated with topotecan.

L Liebes; M Potmesil; T Kim; D Pease; M Buckley; D Fry; J Cho; H Adler; K Dar; A Zeleniuch-Jacquotte; H Hochster

Research Articles

The prognostic role of p53, metallothionein, P-glycoprotein, and MIB-1 in muscle-invasive urothelial transitional cell carcinoma.

L L Siu; D Banerjee; R J Khurana; X Pan; R Pflueger; I F Tannock; M J Moore

The overexpression of RHAMM, a hyaluronan-binding protein that regulates ras signaling, correlates with overexpression of mitogen-activated protein kinase and is a significant parameter in breast cancer progression.

C Wang; A D Thor; D H Moore, 2nd; Y Zhao; R Kerschmann; R Stern; P H Watson; E A Turley

Expression of Bcl-X(L), an antiapoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma.

M Torzewski; M Sarbia; H Heep; P Dutkowski; R Willers; H E Gabbert

Minimal recruitment and activation of dendritic cells within renal cell carcinoma.

A J Troy; K L Summers; P J Davidson; C H Atkinson; D N Hart

Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks.

S G Eckhardt; S D Baker; J R Eckardt; T G Burke; D L Warner; J G Kuhn; G Rodriguez; S Fields; A Thurman; L Smith; M L Rothenberg; L White; P Wissel; R Kunka; S DePee; D Littlefield; H A Burris; D D Von Hoff; E K Rowinsky

A phase I and pharmacokinetic study of LY231514, the multitargeted antifolate.

A C McDonald; P A Vasey; L Adams; J Walling; J R Woodworth; T Abrahams; S McCarthy; N P Bailey; N Siddiqui; M J Lind; A H Calvert; C J Twelves; J Cassidy; S B Kaye

Phase Ib trial of bryostatin 1 in patients with refractory malignancies.

S Grant; J Roberts; E Poplin; M B Tombes; B Kyle; D Welch; M Carr; H D Bear

Active immunotherapy with ultraviolet B-irradiated autologous whole melanoma cells plus DETOX in patients with metastatic melanoma.

O Eton; D D Kharkevitch; M A Gianan; M I Ross; K Itoh; M W Pride; C Donawho; A C Buzaid; P F Mansfield; J E Lee; S S Legha; C Plager; N E Papadopoulos; A Y Bedikian; R S Benjamin; C M Balch

Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors.

B A Conley; M J Egorin; N Tait; D M Rosen; E A Sausville; G Dover; R J Fram; D A Van Echo

Phase I/II trial of all-trans retinoic acid and tamoxifen in patients with advanced breast cancer.

G T Budd; P C Adamson; M Gupta; P Homayoun; S K Sandstrom; R F Murphy; D McLain; L Tuason; D Peereboom; R M Bukowski; R Ganapathi

Interferon-gamma and monoclonal antibody 131I-labeled CC49: outcomes in patients with androgen-independent prostate cancer.

S F Slovin; H I Scher; C R Divgi; V Reuter; G Sgouros; M Moore; K Weingard; R Pettengall; M Imbriaco; A El-Shirbiny; R Finn; J Bronstein; C Brett; D Milenic; A Dnistrian; L Shapiro; J Schlom; S M Larson

Pharmacokinetics of cladribine in plasma and its 5'-monophosphate and 5'-triphosphate in leukemic cells of patients with chronic lymphocytic leukemia.

F Albertioni; S Lindemalm; V Reichelova; B Pettersson; S Eriksson; G Juliusson; J Liliemark

Significance of circulating hepatocyte growth factor level as a prognostic indicator in primary breast cancer.

M Toi; T Taniguchi; T Ueno; M Asano; N Funata; K Sekiguchi; H Iwanari; T Tominaga

Epstein-Barr viral DNA in serum of patients with nasopharyngeal carcinoma.

A Mutirangura; W Pornthanakasem; A Theamboonlers; V Sriuranpong; P Lertsanguansinchi; S Yenrudi; N Voravud; P Supiyaphun; Y Poovorawan

Prognostic value of chorionic gonadotropin beta gene transcripts in human breast carcinoma.

I Bièche; V Lazar; C Noguès; T Poynard; Y Giovangrandi; D Bellet; R Lidereau; M Vidaud

Proliferative activity and micronucleus frequency after radiation of lung cancer cells as assessed by the cytokinesis-block method and their relationship to clinical outcome.

Y Shibamoto; O Ike; H Mizuno; T Fukuse; S Hitomi; M Takahashi

Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II.

A A Adjei; M Charron; E K Rowinsky; P A Svingen; J Miller; J M Reid; J Sebolt-Leopold; M M Ames; S H Kaufmann

Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine.

S M Melana; J F Holland; B G Pogo

Tamoxifen-resistant fibroblast growth factor-transfected MCF-7 cells are cross-resistant in vivo to the antiestrogen ICI 182,780 and two aromatase inhibitors.

S W McLeskey; L Zhang; D El-Ashry; B J Trock; C A Lopez; S Kharbanda; C A Tobias; L A Lorant; R S Hannum; R B Dickson; F G Kern

Efficient generation of autologous peripheral blood-derived cytotoxic T lymphocytes against poorly immunogenic human tumors using recombinant CD80-adenovirus together with interleukin 12 and interleukin 2.

S Mogi; T Ebata; Y Setoguchi; M Fujime; Y Heike; T Kohsaka; H Yagita; K Okumura; M Azuma

Bispecific antibodies increase T-cell stimulatory capacity in vitro of human autologous virus-modified tumor vaccine.

C Haas; G Strauss; G Moldenhauer; R M Iorio; V Schirrmacher

Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.

L Yang; R Hwang; Y Chiang; E M Gordon; W F Anderson; D Parekh

Studies of the efficacy and pharmacology of irinotecan against human colon tumor xenograft models.

W C Zamboni; C F Stewart; P J Cheshire; L B Richmond; S K Hanna; X Luo; C Poquette; J P McGovren; J A Houghton; P J Houghton

Synergistic effects of 8-chlorocyclic-AMP and retinoic acid on induction of apoptosis in Ewing's sarcoma CHP-100 cells.

R K Srivastava; A R Srivastava; Y S Cho-Chung

Combined antitumor effect of radiation and ibuprofen in human prostate carcinoma cells.

S T Palayoor; E A Bump; S K Calderwood; S Bartol; C N Coleman

Chemosensitization of glioblastoma cells to bis-dichloroethyl-nitrosourea with tyrphostin AG17.

B C Liang; E Ullyatt

Phenytoin alters the disposition of topotecan and N-desmethyl topotecan in a patient with medulloblastoma.

W C Zamboni; A J Gajjar; R L Heideman; J H Beijnen; H Rosing; P J Houghton; C F Stewart

Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas.

T Vogt; W Stolz; J Welsh; B Jung; R S Kerbel; H Kobayashi; M Landthaler; M McClelland

Lineage-negative human leukocyte antigen-DR+ cells with the phenotype of undifferentiated dendritic cells in patients with carcinoma of the abdomen and pelvis.

B Melichar; C Savary; A P Kudelka; C Verschraegen; J J Kavanagh; C L Edwards; C D Platsoucas; R S Freedman

Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas.

S I Wang; R Parsons; M Ittmann

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