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Volume 3, Issue 3

1 March 1997

Front Matter
Table of Contents
Back Matter
Editorial Board

ISSN 1078-0432

EISSN 1557-3265

Issue Sections

Advances in Brief
Research Articles
Letter to the Editor

Advances in Brief

Effect of tumor necrosis factor alpha on vascular resistance, nitric oxide production, and glucose and oxygen consumption in perfused tissue-isolated human melanoma xenografts.

C A Kristensen; S Roberge; R K Jain

Research Articles

Pharmacokinetic features, immunogenicity, and toxicity of B43(anti-CD19)-pokeweed antiviral protein immunotoxin in cynomolgus monkeys.

F M Uckun; Y Yanishevski; N Tumer; B Waurzyniak; Y Messinger; L M Chelstrom; E A Lisowski; O Ek; T Zeren; H Wendorf; M C Langlie; J D Irvin; D E Myers; G B Fuller; W Evans; R Gunther

Characterization of vascular leak syndrome induced by the toxin component of Pseudomonas exotoxin-based immunotoxins and its potential inhibition with nonsteroidal anti-inflammatory drugs.

C B Siegall; D Liggitt; D Chace; B Mixan; J Sugai; T Davidson; M Steinitz

Induction of apoptosis in multidrug-resistant and radiation-resistant acute myeloid leukemia cells by a recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor.

J P Perentesis; K G Waddick; A E Bendel; Y Shao; B E Warman; M Chandan-Langlie; F M Uckun

Adenoviral vectors efficiently target cell lines derived from selected lymphocytic malignancies, including anaplastic large cell lymphoma and Hodgkin's disease.

T C Meeker; L T Lay; J M Wroblewski; F Turturro; Z Li; P Seth

Phase I study of the antineovascularization drug CM101.

R F DeVore; C G Hellerqvist; G B Wakefield; B D Wamil; G B Thurman; P A Minton; H W Sundell; H P Yan; C E Carter; Y F Wang; G E York; M H Zhang; D H Johnson

Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.

R Perez-Soler; D M Shin; Z H Siddik; W K Murphy; M Huber; S J Lee; A R Khokhar; W K Hong

A phase I trial of a new recombinant human beta-interferon (BG9015) for the treatment of patients with recurrent gliomas.

H A Fine; P Y Wen; M Robertson; A O'Neill; J Kowal; J S Loeffler; P M Black

A patient with adrenocortical carcinoma: characterization of its biological activity and drug resistance profile.

N Feller; K Hoekman; C M Kuiper; S C Linn; H M Verheul; B G Wolthers; C Popp-Snijders; H M Pinedo

Dihydropyrimidine dehydrogenase activity in hepatocellular carcinoma: implication in 5-fluorouracil-based chemotherapy.

W Jiang; Z Lu; Y He; R B Diasio

Phase I and pharmacological study of CI-980, a novel synthetic antimicrotubule agent.

E K Rowinsky; G S Long; D A Noe; L B Grochow; M K Bowling; S E Sartorius; R C Donehower

Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies.

M B Atkins; M J Robertson; M Gordon; M T Lotze; M DeCoste; J S DuBois; J Ritz; A B Sandler; H D Edington; P D Garzone; J W Mier; C M Canning; L Battiato; H Tahara; M L Sherman

Neurotoxicity of CI-980, a novel mitotic inhibitor.

C A Meyers; A P Kudelka; C A Conrad; C K Gelke; W Grove; R Pazdur

Efficacy of systemic administration of irinotecan against neuroblastoma xenografts.

J Thompson; W C Zamboni; P J Cheshire; L Lutz; X Luo; Y Li; J A Houghton; C F Stewart; P J Houghton

Presence of methylthioadenosine phosphorylase (MTAP) in hematopoietic stem/progenitor cells: its therapeutic implication for MTAP (-) malignancies.

J Yu; A Batova; L Shao; C J Carrera; A L Yu

8-Chloro-cyclic AMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer.

C Bianco; G Tortora; G Baldassarre; R Caputo; G Fontanini; S Chinè; A R Bianco; F Ciardiello

Paclitaxel cytotoxicity against human lung cancer cell lines increases with prolonged exposure durations.

M S Georgiadis; E K Russell; A F Gazdar; B E Johnson

Antiproliferative activity in vitro and in vivo of the spicamycin analogue KRN5500 with altered glycoprotein expression in vitro.

A M Burger; G Kaur; M Hollingshead; R T Fischer; K Nagashima; L Malspeis; K L Duncan; E A Sausville

Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA: relation to bcl-2 expression, hormone receptors, and lymph node metastases.

O S Frankfurt; J A Robb; E V Sugarbaker; L Villa

Prognostic significance of chromosome 17p deletions in childhood primitive neuroectodermal tumors (medulloblastomas) of the central nervous system.

J A Biegel; A J Janss; C Raffel; L Sutton; L B Rorke; J M Harper; P C Phillips

High frequency of K-ras codon 12 mutations in bronchoalveolar lavage fluid of patients at high risk for second primary lung cancer.

F M Scott; R Modali; T A Lehman; M Seddon; K Kelly; E C Dempsey; V Wilson; M S Tockman; J L Mulshine

Decreased antigen presentation by dendritic cells in patients with breast cancer.

D I Gabrilovich; J Corak; I F Ciernik; D Kavanaugh; D P Carbone

Letter to the Editor

Combining cyclosporin with chemotherapy controls intraocular retinoblastoma without requiring radiation.

M J Greenwald; L C Strauss

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