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Issues

Volume 3, Issue 12
1 December 1997
Issue Cover
All Issues
ISSN 1078-0432
EISSN 1557-3265

Advances in Brief

Platelet: transporter of vascular endothelial growth factor.
H M Verheul; K Hoekman; S Luykx-de Bakker; C A Eekman; C C Folman; H J Broxterman; H M Pinedo
View articletitled, Platelet: transporter of vascular endothelial growth factor.
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Priming for T-cell-mediated rejection of established tumors by cutaneous DNA immunization.
H M Ross; L W Weber; S Wang; G Piskun; R Dyall; P Song; Y Takechi; J Nikolić-Zugić; A N Houghton; J J Lewis
View articletitled, Priming for T-cell-mediated rejection of established tumors by cutaneous DNA immunization.
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Isolated limb perfusion in the sarcoma-bearing rat: a novel preclinical gene delivery system.
M Milas; B Feig; D Yu; N Oriuchi; D Cromeens; T Ge; F C Wong; E E Kim; R Pollock
View articletitled, Isolated limb perfusion in the sarcoma-bearing rat: a novel preclinical gene delivery system.
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The fas signaling pathway is functional in colon carcinoma cells and induces apoptosis.
J A Houghton; F G Harwood; A A Gibson; D M Tillman
View articletitled, The fas signaling pathway is functional in colon carcinoma cells and induces apoptosis.
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Research Articles

Expression of fas (CD95/APO-1) antigen induced by radiation therapy for diffuse B-cell lymphoma: immunohistochemical study.
Y Ogawa; A Nishioka; N Hamada; M Terashima; T Inomata; S Yoshida; H Seguchi; S Kishimoto
View articletitled, Expression of fas (CD95/APO-1) antigen induced by radiation therapy for diffuse B-cell lymphoma: immunohistochemical study.
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In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor.
J P Perentesis; R Gunther; B Waurzyniak; Y Yanishevski; D E Myers; O Ek; Y Messinger; Y Shao; L M Chelstrom; E Schneider; W E Evans; F M Uckun
View articletitled, In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor.
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Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus.
H Takeuchi; S Ozawa; N Ando; C H Shih; K Koyanagi; M Ueda; M Kitajima
View articletitled, Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus.
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Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression.
M S Tockman; J L Mulshine; S Piantadosi; Y S Erozan; P K Gupta; J C Ruckdeschel; P R Taylor; T Zhukov; W H Zhou; Y L Qiao; S X Yao
View articletitled, Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression.
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Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer.
I Osman; H Scher; Z F Zhang; T J Soos; R Hamza; S Eissa; H Khaled; A Koff; C Cordon-Cardo
View articletitled, Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer.
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Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomas.
F Ali-Osman; J M Brunner; T M Kutluk; K Hess
View articletitled, Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomas.
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Prognostic significance of urokinase-type plasminogen activator expression in squamous cell carcinomas of the esophagus.
M Torzewski; M Sarbia; P Verreet; P Dutkowski; H Heep; R Willers; H E Gabbert
View articletitled, Prognostic significance of urokinase-type plasminogen activator expression in squamous cell carcinomas of the esophagus.
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Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade.
Y Guo; G N Sklar; A Borkowski; N Kyprianou
View articletitled, Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade.
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Molecular inhibition of phospholipase cgamma signaling abrogates DU-145 prostate tumor cell invasion.
T Turner; M V Epps-Fung; J Kassis; A Wells
View articletitled, Molecular inhibition of phospholipase cgamma signaling abrogates DU-145 prostate tumor cell invasion.
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Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide.
K Xie; D Bielenberg; S Huang; L Xu; T Salas; S H Juang; Z Dong; I J Fidler
View articletitled, Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide.
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Loss of uteroglobin expression in prostate cancer: relationship to advancing grade.
A T Weeraratna; J A Cajigas; A Schwartz; E G Enquist; M J Manyak; S R Patierno
View articletitled, Loss of uteroglobin expression in prostate cancer: relationship to advancing grade.
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Immunohistochemical study of c-fos-positive lymphocytes infiltrated into human squamous cell carcinomas of the head and neck during radiation therapy and its clinical significance.
Y Ogawa; A Nishioka; N Hamada; M Terashima; T Inomata; S Yoshida; H Seguchi; S Kishimoto
View articletitled, Immunohistochemical study of c-fos-positive lymphocytes infiltrated into human squamous cell carcinomas of the head and neck during radiation therapy and its clinical significance.
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Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas.
K Takenaga; H Nakanishi; K Wada; M Suzuki; O Matsuzaki; A Matsuura; H Endo
View articletitled, Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas.
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Toward the validation of aneusomy detection by fluorescence in situ hybridization in bladder cancer: comparative analysis with cytology, cytogenetics, and clinical features predicts recurrence and defines clinical testing limitations.
F F Zhang; D A Arber; T G Wilson; M H Kawachi; M L Slovak
View articletitled, Toward the validation of aneusomy detection by fluorescence in situ hybridization in bladder cancer: comparative analysis with cytology, cytogenetics, and clinical features predicts recurrence and defines clinical testing limitations.
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Correlation between the expression of apoptosis-related bcl-2 and p53 oncoproteins and the carcinogenesis and progression of breast carcinomas.
G J Zhang; I Kimijima; R Abe; M Kanno; N Katagata; K Hara; T Watanabe; A Tsuchiya
View articletitled, Correlation between the expression of apoptosis-related bcl-2 and p53 oncoproteins and the carcinogenesis and progression of breast carcinomas.
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High-dose infusional doxorubicin and cyclophosphamide: a feasibility study of tandem high-dose chemotherapy cycles without stem cell support.
R J Morgan, Jr; J H Doroshow; K Venkataraman; K Chang; J Raschko; G Somlo; L Leong; M Tetef; S Shibata; V Hamasaki; K Margolin; S Forman; S Akman; P Coluzzi; C Ahn; L Weiss; U Gadgil; J Harrison
View articletitled, High-dose infusional doxorubicin and cyclophosphamide: a feasibility study of tandem high-dose chemotherapy cycles without stem cell support.
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Phase I trial of orally administered pentosan polysulfate in patients with advanced cancer.
J L Marshall; A Wellstein; J Rae; R J DeLap; K Phipps; J Hanfelt; M K Yunmbam; J X Sun; K L Duchin; M J Hawkins
View articletitled, Phase I trial of orally administered pentosan polysulfate in patients with advanced cancer.
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Effects of a beta-human chorionic gonadotropin subunit immunogen administered in aqueous solution with a novel nonionic block copolymer adjuvant in patients with advanced cancer.
P L Triozzi; V C Stevens; W Aldrich; J Powell; C W Todd; M J Newman
View articletitled, Effects of a beta-human chorionic gonadotropin subunit immunogen administered in aqueous solution with a novel nonionic block copolymer adjuvant in patients with advanced cancer.
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Phase I and pharmacological trial of fazarabine (Ara-AC) with granulocyte colony-stimulating factor.
R M Goldberg; J M Reid; M M Ames; J A Sloan; J Rubin; C Erlichman; M J Kuffel; T R Fitch
View articletitled, Phase I and pharmacological trial of fazarabine (Ara-AC) with granulocyte colony-stimulating factor.
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Phase II trial of alternating weekly chemohormonal therapy for patients with androgen-independent prostate cancer.
J A Ellerhorst; S M Tu; R J Amato; L Finn; R E Millikan; L C Pagliaro; A Jackson; C J Logothetis
View articletitled, Phase II trial of alternating weekly chemohormonal therapy for patients with androgen-independent prostate cancer.
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Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study.
M Beran; S Jeha; S O'Brien; E Estey; L Vitek; M G Zurlo; M B Rios; M Keating; H Kantarjian
View articletitled, Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study.
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Imaging of somatostatin receptors by indium-111-pentetreotide correlates with quantitative determination of somatostatin receptor type 2 gene expression in neuroblastoma tumors.
V Briganti; R Sestini; C Orlando; G Bernini; G La Cava; A Tamburini; C C Raggi; M Serio; M Maggi
View articletitled, Imaging of somatostatin receptors by indium-111-pentetreotide correlates with quantitative determination of somatostatin receptor type 2 gene expression in neuroblastoma tumors.
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Pharmacokinetics of 3-methyl-(triazen-1-yl)imidazole-4-carboximide following administration of temozolomide to patients with advanced cancer.
J M Reid; D C Stevens; J Rubin; M M Ames
View articletitled, Pharmacokinetics of 3-methyl-(triazen-1-yl)imidazole-4-carboximide following administration of temozolomide to patients with advanced cancer.
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Changes in messenger RNA expression of protein kinase A regulatory subunit ialpha in breast cancer patients treated with tamoxifen.
W R Miller; M J Hulme; J M Bartlett; J MacCallum; J M Dixon
View articletitled, Changes in messenger RNA expression of protein kinase A regulatory subunit ialpha in breast cancer patients treated with tamoxifen.
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Altered gene expression in drug-resistant human breast cancer cells.
K Wosikowski; D Schuurhuis; G J Kops; M Saceda; S E Bates
View articletitled, Altered gene expression in drug-resistant human breast cancer cells.
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Adenovirus-mediated delivery of p16 to p16-deficient human bladder cancer cells confers chemoresistance to cisplatin and paclitaxel.
J Grim; A D'Amico; S Frizelle; J Zhou; R A Kratzke; D T Curiel
View articletitled, Adenovirus-mediated delivery of p16 to p16-deficient human bladder cancer cells confers chemoresistance to cisplatin and paclitaxel.
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Induction of antitumor cytotoxic T lymphocytes from the peripheral blood mononuclear cells of cancer patients using HLA-A2-restricted MAGE-3 peptide in vitro.
T Fujie; F Tanaka; M Mori; K Takesako; K Sugimachi; T Akiyoshi
View articletitled, Induction of antitumor cytotoxic T lymphocytes from the peripheral blood mononuclear cells of cancer patients using HLA-A2-restricted MAGE-3 peptide in vitro.
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Docetaxel enhances tumor radioresponse in vivo.
K A Mason; N R Hunter; M Milas; J L Abbruzzese; L Milas
View articletitled, Docetaxel enhances tumor radioresponse in vivo.
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Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen.
K Y Tsang; M Zhu; C A Nieroda; P Correale; S Zaremba; J M Hamilton; D Cole; C Lam; J Schlom
View articletitled, Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen.
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Are angiogenic factors, cytokines, and soluble adhesion molecules prognostic factors in patients with renal cell carcinoma?
C Dosquet; M C Coudert; E Lepage; J Cabane; F Richard
View articletitled, Are angiogenic factors, cytokines, and soluble adhesion molecules prognostic factors in patients with renal cell carcinoma?
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O6-Methylguanine-DNA methyltransferase protein levels in pediatric brain tumors.
S Hongeng; T P Brent; R A Sanford; H Li; L E Kun; R L Heideman
View articletitled, O6-Methylguanine-DNA methyltransferase protein levels in pediatric brain tumors.
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Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
W D Foulkes; N Wong; J S Brunet; L R Bégin; J C Zhang; J J Martinez; F Rozen; P N Tonin; S A Narod; S E Karp; M N Pollak
View articletitled, Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer.
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Biological and clinical significance of concurrent p53 gene alterations, MDR1 gene expression, and S-phase fraction analyses in breast cancer patients treated with primary chemotherapy or radiotherapy.
S Chevillard; J Lebeau; P Pouillart; C de Toma; C Beldjord; B Asselain; J Klijanienko; A Fourquet; H Magdelénat; P Vielh
View articletitled, Biological and clinical significance of concurrent p53 gene alterations, MDR1 gene expression, and S-phase fraction analyses in breast cancer patients treated with primary chemotherapy or radiotherapy.
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Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
N Suehara; K Mizumoto; M Tanaka; H Niiyama; K Yokohata; Y Tominaga; H Shimura; T Muta; N Hamasaki
View articletitled, Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis.
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Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer.
A Giatromanolaki; M I Koukourakis; D Theodossiou; K Barbatis; K O'Byrne; A L Harris; K C Gatter
View articletitled, Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer.
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Establishment of two human prostate cancer cell lines derived from a single bone metastasis.
N M Navone; M Olive; M Ozen; R Davis; P Troncoso; S M Tu; D Johnston; A Pollack; S Pathak; A C von Eschenbach; C J Logothetis
View articletitled, Establishment of two human prostate cancer cell lines derived from a single bone metastasis.
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Immunoglobulins D and M multiple myeloma variants are heavily mutated.
N Juge-Morineau; C Heirman; M Bakkus; B Van Camp; R Malfait; J L Harousseau; K Thielemans; R Bataille
View articletitled, Immunoglobulins D and M multiple myeloma variants are heavily mutated.
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Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue.
I B Joseph; J B Nelson; S R Denmeade; J T Isaacs
View articletitled, Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue.
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Foundations of Clinical Cancer Research: Perspective for the 21st Century

Foundations of Clinical Cancer Research: Perspective for the 21st Century. Proceedings of a symposium honoring Dr. Emil J Freireich. Houston, Texas, March 14-15, 1997.
View articletitled, Foundations of Clinical Cancer Research: Perspective for the 21st Century. Proceedings of a symposium honoring Dr. Emil J Freireich. Houston, Texas, March 14-15, 1997.
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Foundations of clinical cancer research: perspective for the 21st century.
E M Hersh
View articletitled, Foundations of clinical cancer research: perspective for the 21st century.
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Confrontation, passion, and personalization. Emil J. Freireich.
E Frei, 3rd
View articletitled, Confrontation, passion, and personalization. Emil J. Freireich.
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The future of clinical cancer research in the next millennium.
E J Freireich
View articletitled, The future of clinical cancer research in the next millennium.
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The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor.
R Shimamura; G C Fraizer; J Trapman; Lau YfC; G F Saunders
View articletitled, The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor.
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Cytokine deregulation in hematological malignancies: clinical and biological implications.
R Kurzrock
View articletitled, Cytokine deregulation in hematological malignancies: clinical and biological implications.
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Clinical trials in cancer.
J F Holland
View articletitled, Clinical trials in cancer.
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The scientific basis of clinical trials: statistical aspects.
E A Gehan
View articletitled, The scientific basis of clinical trials: statistical aspects.
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Prognostic factors in clinical cancer trials.
E Estey
View articletitled, Prognostic factors in clinical cancer trials.
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Recreating an environment for clinical discovery.
J U Gutterman
View articletitled, Recreating an environment for clinical discovery.
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Leukemia: A model for drug development.
M J Keating
View articletitled, Leukemia: A model for drug development.
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Advances in therapy of multiple myeloma: lessons from acute leukemia.
B Barlogie
View articletitled, Advances in therapy of multiple myeloma: lessons from acute leukemia.
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Drug development in solid tumors: personal perspective of Dr. Emil J Freireich's contributions.
P P Carbone
View articletitled, Drug development in solid tumors: personal perspective of Dr. Emil J Freireich's contributions.
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Advances in the biological therapy and gene therapy of malignant disease.
E M Hersh; A T Stopeck
View articletitled, Advances in the biological therapy and gene therapy of malignant disease.
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Testicular cancer: an oncological success story.
E H Einhorn
View articletitled, Testicular cancer: an oncological success story.
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Multimodality therapy for locally advanced and limited stage IV breast cancer: the impact of effective non-cross-resistance late-consolidation chemotherapy.
G R Blumenschein; A DiStefano; J Caderao; B Fristenberg; J Adams; L H Schweichler; L Drinkard
View articletitled, Multimodality therapy for locally advanced and limited stage IV breast cancer: the impact of effective non-cross-resistance late-consolidation chemotherapy.
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Combined modality therapy of lung cancer.
R B Livingston
View articletitled, Combined modality therapy of lung cancer.
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Freireich's laws in the treatment of sarcomas.
R S Benjamin
View articletitled, Freireich's laws in the treatment of sarcomas.
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Can we cure indolent lymphomas?
F Cabanillas
View articletitled, Can we cure indolent lymphomas?
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The evolution of antibiotic therapy for neutropenic patients.
G P Bodey
View articletitled, The evolution of antibiotic therapy for neutropenic patients.
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Hematopoietic supportive care.
J Hester
View articletitled, Hematopoietic supportive care.
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High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
A R Zander; C Berger; N Kröger; M Stockshläder; W Krüger; M Horstmann; J Grimm; W Zeller; H Kabisch; R Erttmann; P Schönrock; R Kuse; D Braumann; H J Illiger; W Fiedler; M de Witt; K D Hossfeld; H J Weh
View articletitled, High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
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Toward a leukemia treatment strategy based on the probability of stem cell death: an essay in honor of Dr. Emil J Freireich.
E A McCulloch
View articletitled, Toward a leukemia treatment strategy based on the probability of stem cell death: an essay in honor of Dr. Emil J Freireich.
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Prospects for cytokine and chemokine biotherapy.
J J Oppenheim; W J Murphy; O Chertox; V Schirrmacher; J M Wang
View articletitled, Prospects for cytokine and chemokine biotherapy.
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Oncogenes and tumor suppressor genes: therapeutic implications.
S A Stass; J Mixson
View articletitled, Oncogenes and tumor suppressor genes: therapeutic implications.
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Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.
I B Weinstein; M Begemann; P Zhou; E K Han; A Sgambato; Y Doki; N Arber; M Ciaparrone; H Yamamoto
View articletitled, Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy.
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Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.
J Mendelsohn
View articletitled, Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.
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Summary of the first Emil J Freireich symposium.
R C Bast, Jr
View articletitled, Summary of the first Emil J Freireich symposium.
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Who took the clinical out of clinical research?--Mouse versus man: seventh David A Karnofsky Memorial Lecture--1976.
E J Freireich
View articletitled, Who took the clinical out of clinical research?--Mouse versus man: seventh David A Karnofsky Memorial Lecture--1976.
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Chronic myelogenous leukemia--progress at the M. D. Anderson Cancer Center over the past two decades and future directions: first Emil J Freireich Award Lecture.
H M Kantarjian; M Talpaz; S O'Brien; R Kurzrock; J Gutterman; M J Keating; K B McCredie; E J Freireich
View articletitled, Chronic myelogenous leukemia--progress at the M. D. Anderson Cancer Center over the past two decades and future directions: first Emil J Freireich Award Lecture.
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  • Online ISSN 1557-3265
  • Print ISSN 1078-0432

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