Skip Nav Destination
Issues
1 August 2022
-
Cover Image
Cover Image
The cover shows a section of a lymph node biopsy from a patient with diffuse large B-cell lymphoma. Immunoflourescence staining using proximity ligation shows a complex formation between Aiolos and HDAC1 in CD20-positive DLBCL cells. For details, see the article by Hagner and colleagues on page 3367 of this issue. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Reviews
Research Briefs: Clinical Trial Brief Reports
Nivolumab Retreatment in Non–Small Cell Lung Cancer Patients Who Responded to Prior Immune Checkpoint Inhibitors and Had ICI-Free Intervals (WJOG9616L)
Hiroaki Akamatsu; Shunsuke Teraoka; Shinkichi Takamori; Satoru Miura; Hidetoshi Hayashi; Akito Hata; Yukihiro Toi; Yoshimasa Shiraishi; Nobuaki Mamesaya; Yuki Sato; Naoki Furuya; Jun Oyanagi; Yasuhiro Koh; Toshihiro Misumi; Nobuyuki Yamamoto; Kazuhiko Nakagawa
Clinical Trials: Targeted Therapy
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors
Pamela N. Munster; Andrew E. Greenstein; Gini F. Fleming; Erkut Borazanci; Manish R. Sharma; Joseph M. Custodio; Iulia Cristina Tudor; Hristina I. Pashova; Stacie Peacock Shepherd; Andreas Grauer; Jasgit C. Sachdev
Phase II Clinical Trial of Eribulin–Gemcitabine Combination Therapy in Previously Treated Patients With Advanced Liposarcoma or Leiomyosarcoma
Chang Gon Kim; Nam Suk Sim; Jeong Eun Kim; Kum-Hee Yun; Young Han Lee; Seung Hyun Kim; Wooyeol Baek; Yoon Dae Han; Sang Kyum Kim; Jee Hung Kim; Yoon Woo Koh; Inkyung Jung; Su-Jin Shin; Sun Young Rha; Jin-Hee Ahn; Hyo Song Kim
Initial Phase I Safety Study of Gedatolisib plus Cofetuzumab Pelidotin for Patients with Metastatic Triple-Negative Breast Cancer
Milan Radovich; Jeffrey P. Solzak; Chao J. Wang; Bradley A. Hancock; Sunil Badve; Sandra K. Althouse; Steven M. Bray; Anna Maria V. Storniolo; Tarah J. Ballinger; Bryan P. Schneider; Kathy D. Miller
Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study
Deborah M. Stephens; Ying Huang; Amy S. Ruppert; Janek S. Walker; Daniel Canfield; Casey B. Cempre; Qiang Fu; Sharyn Baker; Boyu Hu; Harsh Shah; Renee Vadeboncoeur; Kerry A. Rogers; Seema Bhat; Samantha M. Jaglowski; Hank Lockman; Rosa Lapalombella; John C. Byrd; Jennifer A. Woyach
Telaglenastat plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase II ENTRATA Trial
Chung-Han Lee; Robert Motzer; Hamid Emamekhoo; Marc Matrana; Ivor Percent; James J. Hsieh; Arif Hussain; Ulka Vaishampayan; Sandy Liu; Steven McCune; Vijay Patel; Montaser Shaheen; Johanna Bendell; Alice C. Fan; Benjamin A. Gartrell; Oscar B. Goodman, Jr; Petros G. Nikolinakos; Arash Rezazadeh Kalebasty; Yousef Zakharia; Zhentao Zhang; Hema Parmar; Lalith Akella; Keith Orford; Nizar M. Tannir
VERONICA: Randomized Phase II Study of Fulvestrant and Venetoclax in ER-Positive Metastatic Breast Cancer Post-CDK4/6 Inhibitors – Efficacy, Safety, and Biomarker Results
Geoffrey J. Lindeman; Tharu M. Fernando; Rebecca Bowen; Katarzyna J. Jerzak; Xinni Song; Thomas Decker; Frances Boyle; Steve McCune; Anne Armstrong; Catherine Shannon; Gianfilippo Bertelli; Ching-Wei Chang; Rupal Desai; Kushagra Gupta; Timothy R. Wilson; Aulde Flechais; Aditya Bardia
Clinical Trials: Immunotherapy
Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
Zhanjie Zhang; Bian Wu; Gang Peng; Guixiang Xiao; Jing Huang; Qian Ding; Chengzhang Yang; Xingao Xiong; Hui Ma; Liangliang Shi; Jinsong Yang; Xiaohua Hong; Jielin Wei; You Qin; Chao Wan; Yi Zhong; Yan Zhou; Xueyan Zhao; Yangming Leng; Tao Zhang; Gang Wu; Min Yao; Xiaomeng Zhang; Kunyu Yang
Three-Year Follow-Up and Response–Survival Relationship of Nivolumab in Previously Treated Patients with Advanced Esophageal Squamous Cell Carcinoma (ATTRACTION-3)
Morihito Okada; Ken Kato; Byoung Chul Cho; Masanobu Takahashi; Chen-Yuan Lin; Keisho Chin; Shigenori Kadowaki; Myung-Ju Ahn; Yasuo Hamamoto; Yuichiro Doki; Chueh-Chuan Yen; Yutaro Kubota; Sung-Bae Kim; Chih-Hung Hsu; Eva Holtved; Ioannis Xynos; Yasuhiro Matsumura; Akira Takazawa; Yuko Kitagawa
Precision Medicine and Imaging
Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)
Vera J. Suman; Lili Du; Tanya Hoskin; Meenakshi Anurag; Cynthia Ma; Isabelle Bedrosian; Kelly K. Hunt; Matthew J. Ellis; W. Fraser Symmans
Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response
Toni T. Seppälä; Jacquelyn W. Zimmerman; Reecha Suri; Haley Zlomke; Gabriel D. Ivey; Annamaria Szabolcs; Christopher R. Shubert; John L. Cameron; William R. Burns; Kelly J. Lafaro; Jin He; Christopher L. Wolfgang; Ying S. Zou; Lei Zheng; David A. Tuveson; James R. Eshlemann; David P. Ryan; Alec C. Kimmelman; Theodore S. Hong; David T. Ting; Elizabeth M. Jaffee; Richard A. Burkhart
Perioperative ctDNA-Based Molecular Residual Disease Detection for Non–Small Cell Lung Cancer: A Prospective Multicenter Cohort Study (LUNGCA-1)
Liang Xia; Jiandong Mei; Ran Kang; Senyi Deng; Yaohui Chen; Ying Yang; Gang Feng; Yulan Deng; Fanyi Gan; Yidan Lin; Qiang Pu; Lin Ma; Feng Lin; Yong Yuan; Yang Hu; Chenglin Guo; Hu Liao; Chengwu Liu; Yunke Zhu; Wenping Wang; Zheng Liu; Yuyang Xu; Kaidi Li; Chuan Li; Qingyun Li; Ji He; Weizhi Chen; Xiaolong Zhang; Yingli Kou; Yun Wang; Zhu Wu; Guowei Che; Longqi Chen; Lunxu Liu
Translational Cancer Mechanisms and Therapy
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer
Joshua K. Sabari; Vamsidhar Velcheti; Kazuhide Shimizu; Matthew R. Strickland; Rebecca S. Heist; Mohini Singh; Naema Nayyar; Anita Giobbie-Hurder; Subba R. Digumarthy; Justin F. Gainor; Anant P. Rajan; Edwin Nieblas-Bedolla; Aaron C. Burns; Jill Hallin; Peter Olson; James G. Christensen; Sylvia C. Kurz; Priscilla K. Brastianos; Hiroaki Wakimoto
Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer
Peter A. Fasching; Duan Liu; Steve Scully; James N. Ingle; Paulo C. Lyra, Jr.; Brigitte Rack; Alexander Hein; Arif B. Ekici; Andre Reis; Andreas Schneeweiss; Hans Tesch; Tanja N. Fehm; Georg Heinrich; Matthias W. Beckmann; Matthias Ruebner; Hanna Huebner; Diether Lambrechts; Ebony Madden; Jess Shen; Jane Romm; Kim Doheny; Gregory D. Jenkins; Erin E. Carlson; Liang Li; Brooke L. Fridley; Julie M. Cunningham; Wolfgang Janni; Alvaro N.A. Monteiro; Daniel J. Schaid; Lothar Häberle; Richard M. Weinshilboum; Liewei Wang
Improved T-cell Immunity Following Neoadjuvant Chemotherapy in Ovarian Cancer
Min Liu; Nabihah Tayob; Livius Penter; MacLean Sellars; Anna Tarren; Vipheaviny Chea; Isabel Carulli; Teddy Huang; Shuqiang Li; Su-Chun Cheng; Phuong Le; Laura Frackiewicz; Julia Fasse; Courtney Qi; Joyce F. Liu; Elizabeth H. Stover; Jennifer Curtis; Kenneth J. Livak; Donna Neuberg; Guanglan Zhang; Ursula A. Matulonis; Catherine J. Wu; Derin B. Keskin; Panagiotis A. Konstantinopoulos
Phenotypic Composition of Commercial Anti-CD19 CAR T Cells Affects In Vivo Expansion and Disease Response in Patients with Large B-cell Lymphoma
Chiara Monfrini; Federico Stella; Vanessa Aragona; Martina Magni; Silva Ljevar; Cristina Vella; Eugenio Fardella; Annalisa Chiappella; Francesca Nanetti; Martina Pennisi; Anna Dodero; Anna Guidetti; Paolo Corradini; Cristiana Carniti
The PD-L1/4-1BB Bispecific Antibody–Anticalin Fusion Protein PRS-344/S095012 Elicits Strong T-Cell Stimulation in a Tumor-Localized Manner
Janet K. Peper-Gabriel; Marina Pavlidou; Lucia Pattarini; Aizea Morales-Kastresana; Thomas J. Jaquin; Catherine Gallou; Eva-Maria Hansbauer; Marleen Richter; Helene Lelievre; Alix Scholer-Dahirel; Birgit Bossenmaier; Celine Sancerne; Matthieu Riviere; Maximilien Grandclaudon; Markus Zettl; Rachida S. Bel Aiba; Christine Rothe; Veronique Blanc; Shane A. Olwill
Letters to the Editor
Advertisement
Email alerts
NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale within the United States of Bavencio® (avelumab), a pharmaceutical owned by Merck. If any resulting funds are received, they would not be used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.
RSS Feeds