Skip Nav Destination
Issues
15 June 2019
-
Cover Image
Cover Image
The cover shows a section of lung from a PDX model of adult T-cell leukemia/lymphoma. Hematoxylin and eosin (H&E) staining shows congested alveolar septa with frequent neutrophils but complete absence of neoplastic cells. For details, see the article by Chung and colleagues on page 3589 of this issue. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Review
Clinical Trials: Targeted Therapy
Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial
Jianming Xu; Jie Li; Chunmei Bai; Nong Xu; Zhiwei Zhou; Zhiping Li; Caicun Zhou; Ru Jia; Ming Lu; Yuejuan Cheng; Chenyu Mao; Wei Wang; Ke Cheng; Chunxia Su; Ye Hua; Chuan Qi; Jing Li; Wei Wang; Ke Li; Qiaoling Sun; Yongxin Ren; Weiguo Su
Clinical Trials: Immunotherapy
Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors
Tanios Bekaii-Saab; Robert Wesolowski; Daniel H. Ahn; Christina Wu; Amir Mortazavi; Maryam Lustberg; Bhuvaneswari Ramaswamy; Jeffrey Fowler; Lai Wei; Jay Overholser; Pravin T.P. Kaumaya
Author Choice
Phase 1 Open-Label, Multicenter Study of First-in-Class RORγ Agonist LYC-55716 (Cintirorgon): Safety, Tolerability, and Preliminary Evidence of Antitumor Activity
Devalingam Mahalingam; Judy S. Wang; Erika P. Hamilton; John Sarantopoulos; John Nemunaitis; Garry Weems; Laura Carter; Xiao Hu; Marshall Schreeder; H. Jeffrey Wilkins
Precision Medicine and Imaging
89Zr-labeled Bispecific T-cell Engager AMG 211 PET Shows AMG 211 Accumulation in CD3-rich Tissues and Clear, Heterogeneous Tumor Uptake
Kirsten L. Moek; Stijn J.H. Waaijer; Iris C. Kok; Frans V. Suurs; Adrienne H. Brouwers; C. Willemien Menke-van der Houven van Oordt; Thijs T. Wind; Jourik A. Gietema; Carolien P. Schröder; Shekar V.K. Mahesh; Annelies Jorritsma-Smit; Marjolijn N. Lub-de Hooge; Rudolf S.N. Fehrmann; Derk Jan A. de Groot; Elisabeth G.E. de Vries
Author Choice
Radiomics of Multiparametric MRI for Pretreatment Prediction of Pathologic Complete Response to Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study
Zhenyu Liu; Zhuolin Li; Jinrong Qu; Renzhi Zhang; Xuezhi Zhou; Longfei Li; Kai Sun; Zhenchao Tang; Hui Jiang; Hailiang Li; Qianqian Xiong; Yingying Ding; Xinming Zhao; Kun Wang; Zaiyi Liu; Jie Tian
Author Choice
Analysis of Mucosal Melanoma Whole-Genome Landscapes Reveals Clinically Relevant Genomic Aberrations
Rong Zhou; Chaoji Shi; Wenjie Tao; Jiang Li; Jing Wu; Yong Han; Guizhu Yang; Ziyue Gu; Shengming Xu; Yujue Wang; Lizhen Wang; Yanan Wang; Guoyu Zhou; Chenping Zhang; Zhiyuan Zhang; Shuyang Sun
Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III Trial
Françoise Rothé; Maria Joao Silva; David Venet; Christine Campbell; Ian Bradburry; Ghizlane Rouas; Evandro de Azambuja; Marion Maetens; Debora Fumagalli; Vanessa Rodrik-Outmezguine; Serena Di Cosimo; Daniela Rosa; Stephen Chia; Andrew Wardley; Takayuki Ueno; Wolfgang Janni; Jens Huober; Jose Baselga; Martine Piccart; Sherene Loi; Christos Sotiriou; Sarah-Jane Dawson; Michail Ignatiadis
Translational Cancer Mechanisms and Therapy
PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma
Elaine Y. Chung; Yun Mai; Urvi A. Shah; Yongqiang Wei; Elise Ishida; Keisuke Kataoka; Xiaoxin Ren; Kith Pradhan; Boris Bartholdy; Xiaolei Wei; Yiyu Zou; Jinghang Zhang; Seishi Ogawa; Ulrich Steidl; Xingxing Zang; Amit Verma; Murali Janakiram; B. Hilda Ye
Glioblastoma-Derived IL6 Induces Immunosuppressive Peripheral Myeloid Cell PD-L1 and Promotes Tumor Growth
Jonathan B. Lamano; Jason Balquidera Lamano; Yuping D. Li; Joseph D. DiDomenico; Winward Choy; Dorina Veliceasa; Daniel E. Oyon; Shayan Fakurnejad; Leonel Ampie; Kartik Kesavabhotla; Rajwant Kaur; Gurvinder Kaur; Dauren Biyashev; Dusten J. Unruh; Craig M. Horbinski; C. David James; Andrew T. Parsa; Orin Bloch
Author Choice
Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity
Xiaoqing Jia; Chunjie Li; Lihui Li; Xiaoli Liu; Lisha Zhou; Wenjuan Zhang; Shuaishuai Ni; Yun Lu; Li Chen; Lak Shin Jeong; Jinha Yu; Yingjian Zhang; Jianping Zhang; Simin He; Xin Hu; Hefen Sun; Keda Yu; Guangyu Liu; Hu Zhao; Yanmei Zhang; Lijun Jia; Zhi-Ming Shao
Author Choice
Long Noncoding RNA MPRL Promotes Mitochondrial Fission and Cisplatin Chemosensitivity via Disruption of Pre-miRNA Processing
Tian Tian; Xiaobin Lv; Guokai Pan; Yingjuan Lu; Weixiong Chen; Wang He; Xinyuan Lei; Hanqing Zhang; Mo Liu; Sheng Sun; Zhanpeng Ou; Xinyu Lin; Lei Cai; Lile He; Zhiming Tu; Xinhui Wang; Bakhos A. Tannous; Soldano Ferrone; Jinsong Li; Song Fan
Author Choice
Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Venkatrao Vantaku; Jianrong Dong; Chandrashekar R. Ambati; Dimuthu Perera; Sri Ramya Donepudi; Chandra Sekhar Amara; Vasanta Putluri; Shiva Shankar Ravi; Matthew J. Robertson; Danthasinghe Waduge Badrajee Piyarathna; Mariana Villanueva; Friedrich-Carl von Rundstedt; Balasubramanyam Karanam; Leomar Y. Ballester; Martha K. Terris; Roni J. Bollag; Seth P. Lerner; Andrea B. Apolo; Hugo Villanueva; MinJae Lee; Andrew G. Sikora; Yair Lotan; Arun Sreekumar; Cristian Coarfa; Nagireddy Putluri
Author Choice
A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer
Elin Sjöberg; Max Meyrath; Laura Milde; Mercedes Herrera; John Lövrot; Daniel Hägerstrand; Oliver Frings; Margarita Bartish; Charlotte Rolny; Erik Sonnhammer; Andy Chevigné; Martin Augsten; Arne Östman
SS18-SSX–Dependent YAP/TAZ Signaling in Synovial Sarcoma
Ilka Isfort; Magdalene Cyra; Sandra Elges; Sareetha Kailayangiri; Bianca Altvater; Claudia Rossig; Konrad Steinestel; Inga Grünewald; Sebastian Huss; Eva Eßeling; Jan-Henrik Mikesch; Susanne Hafner; Thomas Simmet; Agnieszka Wozniak; Patrick Schöffski; Olle Larsson; Eva Wardelmann; Marcel Trautmann; Wolfgang Hartmann
Author Choice
The Caspase-3/PKCδ/Akt/VEGF-A Signaling Pathway Mediates Tumor Repopulation during Radiotherapy
Jin Cheng; Sijia He; Min Wang; Ling Zhou; Zhengxiang Zhang; Xiao Feng; Yang Yu; Jingjing Ma; Chenyun Dai; Shengping Zhang; Lianhui Sun; Yanping Gong; Yiwei Wang; Minghui Zhao; Yuntao Luo; Xinjian Liu; Ling Tian; Chuanyuan Li; Qian Huang
Advertisement
Email alerts
NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck. None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.
RSS Feeds