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1 March 2018
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Cover Image
Cover Image
The cover shows high-grade dysplasia lesions along the squamocolumnar junction (SCJ) or cardia in a mouse model of Barrett Esophagus and adenocarcinoma with immune and stromal cell infiltration. PET tracer ex vivo autoradiography showed that CXCR4 is a specific marker for such immune and epithelial cells that accumulate gradually while dysplasia progresses, which are mediators of disease progression and therefore emerge as a potential biomarker in humans. For details, see the article by Fang and colleagues on page 1048 of this issue. - PDF Icon PDF LinkTable of Contents
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ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Statistics in CCR
Review
Cancer Therapy: Clinical
Ipilimumab plus Lenalidomide after Allogeneic and Autologous Stem Cell Transplantation for Patients with Lymphoid Malignancies
Issa F. Khouri; Irina Fernandez Curbelo; Francesco Turturro; Elias J. Jabbour; Denái R. Milton; Roland L. Bassett, Jr; Luis M. Vence; James P. Allison; Alison M. Gulbis; Padmanee Sharma
NY-ESO-1 Vaccination in Combination with Decitabine Induces Antigen-Specific T-lymphocyte Responses in Patients with Myelodysplastic Syndrome
Elizabeth A. Griffiths; Pragya Srivastava; Junko Matsuzaki; Zachary Brumberger; Eunice S. Wang; Justin Kocent; Austin Miller; Gregory W. Roloff; Hong Yuen Wong; Benjamin E. Paluch; Linda G. Lutgen-Dunckley; Brandon L. Martens; Kunle Odunsi; Adam R. Karpf; Christopher S. Hourigan; Michael J. Nemeth
Efficacy, Safety, and Pharmacokinetics of Axitinib in Nasopharyngeal Carcinoma: A Preclinical and Phase II Correlative Study
Edwin P. Hui; Brigette B. Y. Ma; Herbert H. F. Loong; Frankie Mo; Leung Li; Ann D. King; Ki Wang; Anil T. Ahuja; Charles M. L. Chan; Connie W. C. Hui; Chi H. Wong; Anthony T. C. Chan
The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2)
Dara L. Aisner; Lynette M. Sholl; Lynne D. Berry; Michael R. Rossi; Heidi Chen; Junya Fujimoto; Andre L. Moreira; Suresh S. Ramalingam; Liza C. Villaruz; Gregory A. Otterson; Eric Haura; Katerina Politi; Bonnie Glisson; Jeremy Cetnar; Edward B. Garon; Joan Schiller; Saiama N. Waqar; Lecia V. Sequist; Julie Brahmer; Yu Shyr; Kelly Kugler; Ignacio I. Wistuba; Bruce E. Johnson; John D. Minna; Mark G. Kris; Paul A. Bunn; David J. Kwiatkowski; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators; for the LCMC2 investigators
Personalized Medicine and Imaging
CXCR4 Is a Potential Target for Diagnostic PET/CT Imaging in Barrett's Dysplasia and Esophageal Adenocarcinoma
Hsin-Yu Fang; Natasha Stephens Münch; Margret Schottelius; Jonas Ingermann; Haibo Liu; Michael Schauer; Stefan Stangl; Gabriele Multhoff; Katja Steiger; Carlos Gerngroß; Moritz Jesinghaus; Wilko Weichert; Anja A. Kühl; Antonia R. Sepulveda; Hans-Jürgen Wester; Timothy C. Wang; Michael Quante
Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular Subtypes
Jonathan M. Loree; Allan A.L. Pereira; Michael Lam; Alexandra N. Willauer; Kanwal Raghav; Arvind Dasari; Van. K Morris; Shailesh Advani; David G. Menter; Cathy Eng; Kenna Shaw; Russell Broaddus; Mark J. Routbort; Yusha Liu; Jeffrey S. Morris; Rajyalakshmi Luthra; Funda Meric-Bernstam; Michael J. Overman; Dipen Maru; Scott Kopetz
Residual Convolutional Neural Network for the Determination of IDH Status in Low- and High-Grade Gliomas from MR Imaging
Ken Chang; Harrison X. Bai; Hao Zhou; Chang Su; Wenya Linda Bi; Ena Agbodza; Vasileios K. Kavouridis; Joeky T. Senders; Alessandro Boaro; Andrew Beers; Biqi Zhang; Alexandra Capellini; Weihua Liao; Qin Shen; Xuejun Li; Bo Xiao; Jane Cryan; Shakti Ramkissoon; Lori Ramkissoon; Keith Ligon; Patrick Y. Wen; Ranjit S. Bindra; John Woo; Omar Arnaout; Elizabeth R. Gerstner; Paul J. Zhang; Bruce R. Rosen; Li Yang; Raymond Y. Huang; Jayashree Kalpathy-Cramer
Biomarkers of Primary Resistance to Trastuzumab in HER2-Positive Metastatic Gastric Cancer Patients: the AMNESIA Case-Control Study
Filippo Pietrantonio; Giovanni Fucà; Federica Morano; Annunziata Gloghini; Simona Corso; Giuseppe Aprile; Federica Perrone; Ferdinando De Vita; Elena Tamborini; Gianluca Tomasello; Ambra Vittoria Gualeni; Elena Ongaro; Adele Busico; Elisa Giommoni; Chiara Costanza Volpi; Maria Maddalena Laterza; Salvatore Corallo; Michele Prisciandaro; Maria Antista; Alessandro Pellegrinelli; Lorenzo Castagnoli; Serenella M. Pupa; Giancarlo Pruneri; Filippo de Braud; Silvia Giordano; Chiara Cremolini; Maria Di Bartolomeo
Cancer Therapy: Preclinical
Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS-Mutant Cancers
Heinz Hammerlindl; Dinoop Ravindran Menon; Sabrina Hammerlindl; Abdullah Al Emran; Joachim Torrano; Katrin Sproesser; Divya Thakkar; Min Xiao; Victoria G. Atkinson; Brian Gabrielli; Nikolas K. Haass; Meenhard Herlyn; Clemens Krepler; Helmut Schaider
Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo
Hong Qin; Guowei Wei; Ippei Sakamaki; Zhenyuan Dong; Wesley A. Cheng; D. Lynne Smith; Feng Wen; Han Sun; Kunhwa Kim; Soungchul Cha; Laura Bover; Sattva S. Neelapu; Larry W. Kwak
Author Choice
Novel Targeting of Transcription and Metabolism in Glioblastoma
Yu-Ting Su; Robert Chen; Herui Wang; Hua Song; Qi Zhang; Li-Yuan Chen; Hallie Lappin; Gabriel Vasconcelos; Adrian Lita; Dragan Maric; Aiguo Li; Orieta Celiku; Wei Zhang; Kristan Meetze; Thomas Estok; Mioara Larion; Mones Abu-Asab; Zhengping Zhuang; Chunzhang Yang; Mark R. Gilbert; Jing Wu
Author Choice
Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer
Daniel Dávila-González; Dong Soon Choi; Roberto R. Rosato; Sergio M. Granados-Principal; John G. Kuhn; Wen-Feng Li; Wei Qian; Wen Chen; Anthony J. Kozielski; Helen Wong; Bhuvanesh Dave; Jenny C. Chang
Author Choice
HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue
Guopei Zheng; Zhijie Zhang; Hao Liu; Yan Xiong; Liyun Luo; Xiaoting Jia; Cong Peng; Qiong Zhang; Nan Li; Yixue Gu; Minying Lu; Ying Song; Hao Pan; Jinbao Liu; Wanqing Liu; Zhimin He
Biology of Human Tumors
Author Choice
Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non–Small Cell Lung Cancer by Activating Src-mediated Bypass Signaling
Mingxiang Ye; Yong Zhang; Hongjun Gao; Yan Xu; Pengyu Jing; Jianxiong Wu; Xinxin Zhang; Jie Xiong; Chenfang Dong; Libo Yao; Jian Zhang; Jian Zhang
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