Skip Nav Destination
Issues
15 February 2018
-
Cover Image
Cover Image
The cover shows a branched blood vessel in a tissue section from a patient with glioblastoma. Immunohistochemical staining reveals accumulation of the matrix protein fibulin-3, forming long perivascular fibers. For details, see the article by Nandhu and colleagues on page 821 of this issue. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Statistics in CCR
Review
Author Choice
Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE
Brian M. Alexander; Sujuan Ba; Mitchel S. Berger; Donald A. Berry; Webster K. Cavenee; Susan M. Chang; Timothy F. Cloughesy; Tao Jiang; Mustafa Khasraw; Wenbin Li; Robert Mittman; George H. Poste; Patrick Y. Wen; W.K. Alfred Yung; Anna D. Barker; on behalf of the GBM AGILE Network
Cancer Therapy: Clinical
A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors
Andrea E. Wahner Hendrickson; Michael E. Menefee; Lynn C. Hartmann; Harry J. Long; Donald W. Northfelt; Joel M. Reid; Felix Boakye-Agyeman; Olumide Kayode; Karen S. Flatten; Maria I. Harrell; Elizabeth M. Swisher; Guy G. Poirier; Daniel Satele; Jake Allred; Janet L. Lensing; Alice Chen; Jiuping Ji; Yiping Zang; Charles Erlichman; Paul Haluska; Scott H. Kaufmann
Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib
Ira L. Kraft; Srivandana Akshintala; Yuelin Zhu; Haiyan Lei; Claudia Derse-Anthony; Eva Dombi; Seth M. Steinberg; Maya Lodish; Steven G. Waguespack; Oxana Kapustina; Elizabeth Fox; Frank M. Balis; Maria J. Merino; Paul S. Meltzer; John W. Glod; Jack F. Shern; Brigitte C. Widemann
Autologous Dendritic Cells Pulsed with Allogeneic Tumor Cell Lysate in Mesothelioma: From Mouse to Human
Joachim G.J.V. Aerts; Pauline L. de Goeje; Robin Cornelissen; Margaretha E.H. Kaijen-Lambers; Koen Bezemer; Cor H. van der Leest; Niken M. Mahaweni; André Kunert; Ferry A.L.M. Eskens; Cynthia Waasdorp; Eric Braakman; Bronno van der Holt; Arnold G. Vulto; Rudi W. Hendriks; Joost P.J.J. Hegmans; Henk C. Hoogsteden
Personalized Medicine and Imaging
Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study
Barbara M. Norquist; Mark F. Brady; Maria I. Harrell; Tom Walsh; Ming K. Lee; Suleyman Gulsuner; Sarah S. Bernards; Silvia Casadei; Robert A. Burger; Krishnansu S. Tewari; Floor Backes; Robert S. Mannel; Gretchen Glaser; Cheryl Bailey; Stephen Rubin; John Soper; Heather A. Lankes; Nilsa C. Ramirez; Mary Claire King; Michael J. Birrer; Elizabeth M. Swisher
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab
Martin D. Berger; Sebastian Stintzing; Volker Heinemann; Shu Cao; Dongyun Yang; Yu Sunakawa; Satoshi Matsusaka; Yan Ning; Satoshi Okazaki; Yuji Miyamoto; Mitsukuni Suenaga; Marta Schirripa; Diana L. Hanna; Shivani Soni; Alberto Puccini; Wu Zhang; Chiara Cremolini; Alfredo Falcone; Fotios Loupakis; Heinz-Josef Lenz
Author Choice
Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
Anita Sveen; Jarle Bruun; Peter W. Eide; Ina A. Eilertsen; Lorena Ramirez; Astrid Murumägi; Mariliina Arjama; Stine A. Danielsen; Kushtrim Kryeziu; Elena Elez; Josep Tabernero; Justin Guinney; Hector G. Palmer; Arild Nesbakken; Olli Kallioniemi; Rodrigo Dienstmann; Ragnhild A. Lothe
Cancer Therapy: Preclinical
A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem–Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy
Paolo Luraghi; Viola Bigatto; Elia Cipriano; Gigliola Reato; Francesca Orzan; Francesco Sassi; Francesca De Bacco; Claudio Isella; Sara E. Bellomo; Enzo Medico; Paolo M. Comoglio; Andrea Bertotti; Livio Trusolino; Carla Boccaccio
Author Choice
PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer
Yinhui Yang; Yang Bai; Yundong He; Yu Zhao; Jiaxiang Chen; Linlin Ma; Yunqian Pan; Michael Hinten; Jun Zhang; R. Jeffrey Karnes; Manish Kohli; Jennifer J. Westendorf; Benyi Li; Runzhi Zhu; Haojie Huang; Wanhai Xu
Author Choice
Olaratumab Exerts Antitumor Activity in Preclinical Models of Pediatric Bone and Soft Tissue Tumors through Inhibition of Platelet-Derived Growth Factor Receptor α
Caitlin D. Lowery; Wayne Blosser; Michele Dowless; Shelby Knoche; Jennifer Stephens; Huiling Li; David Surguladze; Nick Loizos; Debra Luffer-Atlas; Gerard J. Oakley, III; Qianxu Guo; Seema Iyer; Brian P. Rubin; Louis Stancato
Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin
Xu Wang; Jonathan J. Beitler; Wen Huang; Guo Chen; Guoqing Qian; Kelly Magliocca; Mihir R. Patel; Amy Y. Chen; Jun Zhang; Sreenivas Nannapaneni; Sungjin Kim; Zhengjia Chen; Xingming Deng; Nabil F. Saba; Zhuo Georgia Chen; Jack L. Arbiser; Dong M. Shin
Biology of Human Tumors
T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
Sarah E. Josefsson; Kanutte Huse; Arne Kolstad; Klaus Beiske; Daniela Pende; Chloé B. Steen; Else Marit Inderberg; Ole Christian Lingjærde; Bjørn Østenstad; Erlend B. Smeland; Ronald Levy; Jonathan M. Irish; June H. Myklebust
Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus–Related Hepatocellular Carcinoma
Yuanfeng Li; Yun Zhai; Qingfeng Song; Haitao Zhang; Pengbo Cao; Jie Ping; Xinyi Liu; Bingqian Guo; Guanjun Liu; Jin Song; Ying Zhang; Aiqing Yang; Hongbo Yan; Liang Yang; Ying Cui; Yilong Ma; Jinliang Xing; Xizhong Shen; Taotao Liu; Hongxin Zhang; Jiaze An; Jin-Xin Bei; Weihua Jia; Longli Kang; Lijun Liu; Dongya Yuan; Zhibin Hu; Hongbing Shen; Lei Lu; Xuan Wang; Hua Li; Fuchu He; Hongxing Zhang; Gangqiao Zhou
FAM198B Is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma via Blockage of ERK-Mediated MMP-1 Expression
Chia-Ying Hsu; Gee-Chen Chang; Yi-Ju Chen; Yi-Chiung Hsu; Yi-Jing Hsiao; Kang-Yi Su; Hsuan-Yu Chen; Chien-Yu Lin; Jin-Shing Chen; Yu-Ju Chen; Qi-Sheng Hong; Wen-Hui Ku; Chih-Ying Wu; Bing-Ching Ho; Ching-Cheng Chiang; Pan-Chyr Yang; Sung-Liang Yu
The Glucocorticoid Receptor Is a Key Player for Prostate Cancer Cell Survival and a Target for Improved Antiandrogen Therapy
Martin Puhr; Julia Hoefer; Andrea Eigentler; Christian Ploner; Florian Handle; Georg Schaefer; Jan Kroon; Angela Leo; Isabel Heidegger; Iris Eder; Zoran Culig; Gabri Van der Pluijm; Helmut Klocker
Author Choice
Whole-Exome Sequencing of Cell-Free DNA Reveals Temporo-spatial Heterogeneity and Identifies Treatment-Resistant Clones in Neuroblastoma
Mathieu Chicard; Leo Colmet-Daage; Nathalie Clement; Adrien Danzon; Mylène Bohec; Virginie Bernard; Sylvain Baulande; Angela Bellini; Paul Deveau; Gaëlle Pierron; Eve Lapouble; Isabelle Janoueix-Lerosey; Michel Peuchmaur; Nadège Corradini; Anne Sophie Defachelles; Dominique Valteau-Couanet; Jean Michon; Valérie Combaret; Olivier Delattre; Gudrun Schleiermacher
Merkel Cell Carcinoma Patients Presenting Without a Primary Lesion Have Elevated Markers of Immunity, Higher Tumor Mutation Burden, and Improved Survival
Natalie Vandeven; Christopher W. Lewis; Vladimir Makarov; Nadeem Riaz; Kelly G. Paulson; Daniel Hippe; Amy Bestick; Ryan Doumani; Tessa Marx; Seesha Takagishi; Timothy A. Chan; Jaehyuk Choi; Paul Nghiem
Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor
Gerardo A. Vitiello; Benjamin D. Medina; Shan Zeng; Timothy G. Bowler; Jennifer Q. Zhang; Jennifer K. Loo; Nesteene J. Param; Mengyuan Liu; Alec J. Moral; Julia N. Zhao; Ferdinand Rossi; Cristina R. Antonescu; Vinod P. Balachandran; Justin R. Cross; Ronald P. DeMatteo
Correction
Advertisement
Email alerts
NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck. None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.
RSS Feeds