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1 February 2018
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Cover Image
Cover Image
The cover shows a section of an intracranial tumor model biopsy from a mouse brain. Hematoxylin and eosin (H&E) staining of the brain tissue displayed that the glioblastoma in the control groups exhibited extensive branch-like growing patterns that spread into the surrounding tissue. For details, see the article by Chen and colleagues on page 684 of this issue. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Reviews
Perspectives
Cancer Therapy: Clinical
Influence of Enzalutamide on Cabazitaxel Pharmacokinetics: a Drug–Drug Interaction Study in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients
Bodine P.S. Belderbos; Sander Bins; Roelof W.F. van Leeuwen; Esther Oomen-de Hoop; Nelly van der Meer; Peter de Bruijn; Paul Hamberg; Esther N.M. Overkleeft; Wendy M. van der Deure; Martijn P. Lolkema; Ronald de Wit; Ron H.J. Mathijssen
Personalized Medicine and Imaging
Author Choice
Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma
Yun-Fan Sun; Wei Guo; Yang Xu; Yin-Hong Shi; Zi-Jun Gong; Yuan Ji; Min Du; Xin Zhang; Bo Hu; Ao Huang; George G. Chen; Paul B.S. Lai; Ya Cao; Shuang-Jian Qiu; Jian Zhou; Xin-Rong Yang; Jia Fan
Author Choice
Cell-Free DNA and Circulating Tumor Cells: Comprehensive Liquid Biopsy Analysis in Advanced Breast Cancer
Giovanna Rossi; Zhaomei Mu; Alfred W. Rademaker; Laura K. Austin; Kimberly S. Strickland; Ricardo Lima Barros Costa; Rebecca J. Nagy; Vittorina Zagonel; Timothy J. Taxter; Amir Behdad; Firas H. Wehbe; Leonidas C. Platanias; William J. Gradishar; Massimo Cristofanilli
Homologous Recombination DNA Repair Pathway Disruption and Retinoblastoma Protein Loss Are Associated with Exceptional Survival in High-Grade Serous Ovarian Cancer
Dale W. Garsed; Kathryn Alsop; Sian Fereday; Catherine Emmanuel; Catherine J. Kennedy; Dariush Etemadmoghadam; Bo Gao; Val Gebski; Valérie Garès; Elizabeth L. Christie; Maartje C.A. Wouters; Katy Milne; Joshy George; Ann-Marie Patch; Jason Li; Gisela Mir Arnau; Timothy Semple; Sreeja R. Gadipally; Yoke-Eng Chiew; Joy Hendley; Thomas Mikeska; Giada V. Zapparoli; Kaushalya Amarasinghe; Sean M. Grimmond; John V. Pearson; Nicola Waddell; Jillian Hung; Colin J.R. Stewart; Raghwa Sharma; Prue E. Allan; Peter F. Rambau; Orla McNally; Linda Mileshkin; Anne Hamilton; Sumitra Ananda; Marisa Grossi; Paul A. Cohen; Yee C. Leung; Robert M. Rome; Philip Beale; Penny Blomfield; Michael Friedlander; Alison Brand; Alexander Dobrovic; Martin Köbel; Paul Harnett; Brad H. Nelson; David D. L. Bowtell; Anna deFazio; Nadia Traficante, for the Australian Ovarian Cancer Study Group
Novel Predictors of Breast Cancer Survival Derived from miRNA Activity Analysis
Vasily N. Aushev; Eunjee Lee; Jun Zhu; Kalpana Gopalakrishnan; Qian Li; Susan L. Teitelbaum; James Wetmur; Davide Degli Esposti; Hector Hernandez-Vargas; Zdenko Herceg; Humberto Parada; Regina M. Santella; Marilie D. Gammon; Jia Chen
Cancer Therapy: Preclinical
Systemic Antitumor Immunity by PD-1/PD-L1 Inhibition Is Potentiated by Vascular-Targeted Photodynamic Therapy of Primary Tumors
Matthew J. O'Shaughnessy; Katie S. Murray; Stephen P. La Rosa; Sadna Budhu; Taha Merghoub; Alexander Somma; Sebastien Monette; Kwanghee Kim; Renato Beluco Corradi; Avigdor Scherz; Jonathan A. Coleman
Biology of Human Tumors
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia
Daniela Di Marcantonio; Esteban Martinez; Simone Sidoli; Jessica Vadaketh; Margaret Nieborowska-Skorska; Anushk Gupta; Jake M. Meadows; Francesca Ferraro; Elena Masselli; Grant A. Challen; Michael D. Milsom; Claudia Scholl; Stefan Fröhling; Siddharth Balachandran; Tomasz Skorski; Benjamin A. Garcia; Prisco Mirandola; Giuliana Gobbi; Ramiro Garzon; Marco Vitale; Stephen M. Sykes
Author Choice
Intratumoral HPV16-Specific T Cells Constitute a Type I–Oriented Tumor Microenvironment to Improve Survival in HPV16-Driven Oropharyngeal Cancer
Marij J.P. Welters; Wenbo Ma; Saskia J.A.M. Santegoets; Renske Goedemans; Ilina Ehsan; Ekaterina S. Jordanova; Vanessa J. van Ham; Vincent van Unen; Frits Koning; Sylvia I. van Egmond; Pornpimol Charoentong; Zlatko Trajanoski; Lilly-Ann van der Velden; Sjoerd H. van der Burg
Author Choice
A Prognostic Bio-Model Based on SQSTM1 and N-Stage Identifies Nasopharyngeal Carcinoma Patients at High Risk of Metastasis for Additional Induction Chemotherapy
Qi Yang; Meng-Xia Zhang; Xiong Zou; You-Ping Liu; Rui You; Tao Yu; Rou Jiang; Yi-Nuan Zhang; Jing-Yu Cao; Ming-Huang Hong; Qing Liu; Ling Guo; Tie-Bang Kang; Xiao-Feng Zhu; Ming-Yuan Chen
Author Choice
The RARS–MAD1L1 Fusion Gene Induces Cancer Stem Cell–like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma
Qian Zhong; Zhi-Hua Liu; Zhi-Rui Lin; Ze-Dong Hu; Li Yuan; Yan-min Liu; Ai-Jun Zhou; Li-Hua Xu; Li-Juan Hu; Zi-Feng Wang; Xin-Yuan Guan; Jia-Jie Hao; Vivian W.Y. Lui; Ling Guo; Hai-Qiang Mai; Ming-Yuan Chen; Fei Han; Yun-Fei Xia; Jennifer R. Grandis; Xing Zhang; Mu-Sheng Zeng
Author Choice
Targeting the MYCN–PARP–DNA Damage Response Pathway in Neuroendocrine Prostate Cancer
Wei Zhang; Bo Liu; Wenhui Wu; Likun Li; Bradley M. Broom; Spyridon P. Basourakos; Dimitrios Korentzelos; Yang Luan; Jianxiang Wang; Guang Yang; Sanghee Park; Abul Kalam Azad; Xuhong Cao; Jeri Kim; Paul G. Corn; Christopher J. Logothetis; Ana M. Aparicio; Arul M. Chinnaiyan; Nora Navone; Patricia Troncoso; Timothy C. Thompson
Blocking the Feedback Loop between Neuroendocrine Differentiation and Macrophages Improves the Therapeutic Effects of Enzalutamide (MDV3100) on Prostate Cancer
Chao Wang; Guang Peng; Hai Huang; Fei Liu; De-Pei Kong; Ke-Qin Dong; Li-He Dai; Zhe Zhou; Kai-Jian Wang; Jun Yang; Yan-Qiong Cheng; Xu Gao; Min Qu; Hong-Ru Wang; Feng Zhu; Qin-Qin Tian; Dan Liu; Li Cao; Xin-Gang Cui; Chuan-Liang Xu; Dan-Feng Xu; Ying-Hao Sun
Correction
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