Skip Nav Destination
Issues
1 October 2018
-
Cover Image
Cover Image
The cover shows a section of a murine squamous cell carcinoma (KLN205). Immunological staining highlights hypoxic regions (green), blood vessels (red) and doxorubicin drug penetration (blue). For details, see the article by Li and colleagues on page 4734 of this issue. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1078-0432
EISSN 1557-3265
Highlights
CCR Translations
Review
Clinical Trials: Targeted Therapy
Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma
Eudocia Q. Lee; Dan G. Duda; Alona Muzikansky; Elizabeth R. Gerstner; John G. Kuhn; David A. Reardon; Lakshmi Nayak; Andrew D. Norden; Lisa Doherty; Debra LaFrankie; Jennifer Stefanik; Trupti Vardam; Katrina H. Smith; Christine McCluskey; Sarah Gaffey; Tracy T. Batchelor; Rakesh K. Jain; Patrick Y. Wen
Author Choice
Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS-Mutated Hepatocellular Carcinoma
Ho Yeong Lim; Philippe Merle; Karl Heinz Weiss; Thomas Yau; Paul Ross; Vincenzo Mazzaferro; Jean-Frédéric Blanc; Yuk Ting Ma; Chia Jui Yen; Judit Kocsis; Su Pin Choo; Wattana Sukeepaisarnjaroen; René Gérolami; Jean-François Dufour; Edward J. Gane; Baek-Yeol Ryoo; Markus Peck-Radosavljevic; Thong Dao; Winnie Yeo; Wisut Lamlertthon; Satawat Thongsawat; Michael Teufel; Katrin Roth; Diego Reis; Barrett H. Childs; Heiko Krissel; Josep M. Llovet
Author Choice
Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival
Emmanuel S. Antonarakis; Eric J. Small; Daniel P. Petrylak; David I. Quinn; Adam S. Kibel; Nancy N. Chang; Erica Dearstyne; Matt Harmon; Dwayne Campogan; Heather Haynes; Tuyen Vu; Nadeem A. Sheikh; Charles G. Drake
Clinical Trials: Immunotherapy
Precision Medicine and Imaging
Author Choice
Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases
Pavitra Kannan; Warren W. Kretzschmar; Helen Winter; Daniel Warren; Russell Bates; Philip D. Allen; Nigar Syed; Benjamin Irving; Bartlomiej W. Papiez; Jakob Kaeppler; Bosjtan Markelc; Paul Kinchesh; Stuart Gilchrist; Sean Smart; Julia A. Schnabel; Tim Maughan; Adrian L. Harris; Ruth J. Muschel; Mike Partridge; Ricky A. Sharma; Veerle Kersemans
Comparison of Longitudinal CA125 Algorithms as a First-Line Screen for Ovarian Cancer in the General Population
Oleg Blyuss; Matthew Burnell; Andy Ryan; Aleksandra Gentry-Maharaj; Inés P. Mariño; Jatinderpal Kalsi; Ranjit Manchanda; John F. Timms; Mahesh Parmar; Steven J. Skates; Ian Jacobs; Alexey Zaikin; Usha Menon
Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance)
Megan Li; Flora Mulkey; Chen Jiang; Bert H. O’Neil; Bryan P. Schneider; Fei Shen; Paula N. Friedman; Yukihide Momozawa; Michiaki Kubo; Donna Niedzwiecki; Howard S. Hochster; Heinz-Josef Lenz; James N. Atkins; Hope S. Rugo; Susan Halabi; William Kevin Kelly; Howard L. McLeod; Federico Innocenti; Mark J. Ratain; Alan P. Venook; Kouros Owzar; Deanna L. Kroetz
Prognostic Value of Methylator Phenotype in Stage III Colon Cancer Treated with Oxaliplatin-based Adjuvant Chemotherapy
Claire Gallois; Julien Taieb; Delphine Le Corre; Karine Le Malicot; Josep Tabernero; Claire Mulot; Jean-François Seitz; Thomas Aparicio; Gunnar Folprecht; Côme Lepage; Enrico Mini; Jean-Luc Van Laethem; Jean-François Emile; Pierre Laurent-Puig; for the PETACC8 investigators
Author Choice
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
Peter Barry; Alexandra Vatsiou; Inmaculada Spiteri; Daniel Nichol; George D. Cresswell; Ahmet Acar; Nicholas Trahearn; Sarah Hrebien; Isaac Garcia-Murillas; Kate Chkhaidze; Luca Ermini; Ian Said Huntingford; Hannah Cottom; Lila Zabaglo; Konrad Koelble; Saira Khalique; Jennifer E. Rusby; Francesca Muscara; Mitch Dowsett; Carlo C. Maley; Rachael Natrajan; Yinyin Yuan; Gaia Schiavon; Nicholas Turner; Andrea Sottoriva
Translational Cancer Mechanisms and Therapy
Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma
Gao Zhang; Lawrence W. Wu; Ilgen Mender; Michal Barzily-Rokni; Marc R. Hammond; Omotayo Ope; Chaoran Cheng; Themistoklis Vasilopoulos; Sergio Randell; Norah Sadek; Aurelie Beroard; Min Xiao; Tian Tian; Jiufeng Tan; Umar Saeed; Eric Sugarman; Clemens Krepler; Patricia Brafford; Katrin Sproesser; Sengottuvelan Murugan; Rajasekharan Somasundaram; Bradley Garman; Bradley Wubbenhorst; Jonathan Woo; Xiangfan Yin; Qin Liu; Dennie T. Frederick; Benchun Miao; Wei Xu; Giorgos C. Karakousis; Xiaowei Xu; Lynn M. Schuchter; Tara C. Mitchell; Lawrence N. Kwong; Ravi K. Amaravadi; Yiling Lu; Genevieve M. Boland; Zhi Wei; Katherine Nathanson; Utz Herbig; Gordon B. Mills; Keith T. Flaherty; Meenhard Herlyn; Jerry W. Shay
CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies
Marina Bacac; Sara Colombetti; Sylvia Herter; Johannes Sam; Mario Perro; Stanford Chen; Roberta Bianchi; Marine Richard; Anne Schoenle; Valeria Nicolini; Sarah Diggelmann; Florian Limani; Ramona Schlenker; Tamara Hüsser; Wolfgang Richter; Katharine Bray-French; Heather Hinton; Anna Maria Giusti; Anne Freimoser-Grundschober; Laurent Lariviere; Christiane Neumann; Christian Klein; Pablo Umaña
Author Choice
Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression
Xiaoming Li; H. Michael Shepard; Jessica A. Cowell; Chunmei Zhao; Ryan J. Osgood; Sanna Rosengren; Barbara Blouw; Sheryl A. Garrovillo; Mark D. Pagel; Clifford J. Whatcott; Haiyong Han; Daniel D. Von Hoff; Darin M. Taverna; Michael J. LaBarre; Daniel C. Maneval; Curtis B. Thompson
Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment
Takuya Kato; Kazuhiro Noma; Toshiaki Ohara; Hajime Kashima; Yuki Katsura; Hiroaki Sato; Satoshi Komoto; Ryoichi Katsube; Takayuki Ninomiya; Hiroshi Tazawa; Yasuhiro Shirakawa; Toshiyoshi Fujiwara
Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer
Elena Bonazzoli; Federica Predolini; Emiliano Cocco; Stefania Bellone; Gary Altwerger; Gulden Menderes; Luca Zammataro; Anna Bianchi; Francesca Pettinella; Francesco Riccio; Chanhee Han; Ghanshyam Yadav; Salvatore Lopez; Aranzazu Manzano; Paola Manara; Natalia Buza; Pei Hui; Serena Wong; Babak Litkouhi; Elena Ratner; Dan-Arin Silasi; Gloria S. Huang; Masoud Azodi; Peter E. Schwartz; Joseph Schlessinger; Alessandro D. Santin
Author Choice
Assessing Therapeutic Efficacy of MEK Inhibition in a KRASG12C-Driven Mouse Model of Lung Cancer
Shuai Li; Shengwu Liu; Jiehui Deng; Esra A. Akbay; Josephine Hai; Chiara Ambrogio; Long Zhang; Fangyu Zhou; Russell W. Jenkins; Dennis O. Adeegbe; Peng Gao; Xiaoen Wang; Cloud P. Paweletz; Grit S. Herter-Sprie; Ting Chen; Laura Gutiérrez-Quiceno; Yanxi Zhang; Ashley A. Merlino; Max M. Quinn; Yu Zeng; Xiaoting Yu; Yuting Liu; Lichao Fan; Andrew J. Aguirre; David A. Barbie; Xianghua Yi; Kwok-Kin Wong
Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival
Vivek Subbiah; Salah-Eddine Lamhamedi-Cherradi; Branko Cuglievan; Brian A. Menegaz; Pamela Camacho; Winston Huh; Vandhana Ramamoorthy; Pete M. Anderson; Raphael E. Pollock; Dina C. Lev; Wei Qiao; Mary Frances McAleer; Robert S. Benjamin; Shreyaskumar Patel; Cynthia E. Herzog; Najat C. Daw; Barry W. Feig; Alexander J. Lazar; Andrea Hayes-Jordan; Joseph A. Ludwig
Author Choice
Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells
Fiona Simpkins; Kibeom Jang; Hyunho Yoon; Karina E. Hew; Minsoon Kim; Diana J. Azzam; Jun Sun; Dekuang Zhao; Tan A. Ince; Wenbin Liu; Wei Guo; Zhi Wei; Gao Zhang; Gordon B. Mills; Joyce M. Slingerland
Author Choice
Chemotherapy Sensitizes Therapy-Resistant Cells to Mild Hyperthermia by Suppressing Heat Shock Protein 27 Expression in Triple-Negative Breast Cancer
Chaofeng Mu; Xiaoyan Wu; Xinyu Zhou; Joy Wolfram; Jianliang Shen; Dechen Zhang; Junhua Mai; Xiaojun Xia; Ashley M. Holder; Mauro Ferrari; Xuewu Liu; Haifa Shen
Advertisement
Email alerts
NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck. None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.
RSS Feeds