Skip Nav Destination
Issues
1 May 2015
-
Cover Image
Cover Image
![issue cover]()
The cover shows establishment of blood brain barrier (BBB) tight junctions. Immunofluorescence staining demonstrates ZO-1 expression within the top endothelial layer of an in vitro BBB. For details, see the article by Jilaveanu and colleagues on page 2138 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
20th Anniversary Commentary
CCR Translations
CCR New Strategies
Molecular Pathways
Reviews
Is This the Time to Introduce Minimal Residual Disease in Multiple Myeloma Clinical Practice?
Bruno Paiva; Noemi Puig; Ramón García-Sanz; Jesús F. San Miguel; on behalf of the Grupo Español de Mieloma (GEM)/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) cooperative study groups
Cancer Therapy: Clinical
Impact of Chronic Graft-versus-Host Disease on Late Relapse and Survival on 7,489 Patients after Myeloablative Allogeneic Hematopoietic Cell Transplantation for Leukemia
Michael Boyiadzis; Mukta Arora; John P. Klein; Anna Hassebroek; Michael Hemmer; Alvaro Urbano-Ispizua; Joseph H. Antin; Brian J. Bolwell; Jean-Yves Y. Cahn; Mitchell S. Cairo; Corey S. Cutler; Mary E. Flowers; Robert P. Gale; Roger Herzig; Luis M. Isola; David A. Jacobsohn; Madan H. Jagasia; Thomas R. Klumpp; Stephanie J. Lee; Effie W. Petersdorf; Stella Santarone; Stephen R. Spellman; Harry C. Schouten; Leo F. Verdonck; John R. Wingard; Daniel J. Weisdorf; Mary M. Horowitz; Steven Z. Pavletic
Personalized Medicine and Imaging
Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial
Lorraine A. Chantrill; Adnan M. Nagrial; Clare Watson; Amber L. Johns; Mona Martyn-Smith; Skye Simpson; Scott Mead; Marc D. Jones; Jaswinder S. Samra; Anthony J. Gill; Nicole Watson; Venessa T. Chin; Jeremy L. Humphris; Angela Chou; Belinda Brown; Adrienne Morey; Marina Pajic; Sean M. Grimmond; David K. Chang; David Thomas; Lucille Sebastian; Katrin Sjoquist; Sonia Yip; Nick Pavlakis; Ray Asghari; Sandra Harvey; Peter Grimison; John Simes; Andrew V. Biankin; on behalf of the Australian Pancreatic Cancer Genome Initiative (APGI) and the Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial Management Committee of the Australasian Gastrointestinal Trials Group (AGITG)
MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial
Michael Weller; Ghazaleh Tabatabai; Bärbel Kästner; Jörg Felsberg; Joachim P. Steinbach; Antje Wick; Oliver Schnell; Peter Hau; Ulrich Herrlinger; Michael C. Sabel; Hans-Georg Wirsching; Ralf Ketter; Oliver Bähr; Michael Platten; Jörg C. Tonn; Uwe Schlegel; Christine Marosi; Roland Goldbrunner; Roger Stupp; Krisztian Homicsko; Josef Pichler; Guido Nikkhah; Jürgen Meixensberger; Peter Vajkoczy; Spyros Kollias; Johannes Hüsing; Guido Reifenberger; Wolfgang Wick; for the DIRECTOR Study Group
Author Choice
PTEN Loss Is Associated with Worse Outcome in HER2-Amplified Breast Cancer Patients but Is Not Associated with Trastuzumab Resistance
Howard M. Stern; Humphrey Gardner; Tomasz Burzykowski; Wafaa Elatre; Carol O'Brien; Mark R. Lackner; Gary A. Pestano; Angela Santiago; Ivonne Villalobos; Wolfgang Eiermann; Tadeusz Pienkowski; Miguel Martin; Nicholas Robert; John Crown; Paolo Nuciforo; Valerie Bee; John Mackey; Dennis J. Slamon; Michael F. Press
Cancer Therapy: Preclinical
Author Choice
Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency
Wan-Ching Yen; Marcus M. Fischer; Fumiko Axelrod; Christopher Bond; Jennifer Cain; Belinda Cancilla; William R. Henner; Rene Meisner; Aaron Sato; Jalpa Shah; Tracy Tang; Breanna Wallace; Min Wang; Chun Zhang; Ann M. Kapoun; John Lewicki; Austin Gurney; Timothy Hoey
Preclinical Pharmacologic Evaluation of Pralatrexate and Romidepsin Confirms Potent Synergy of the Combination in a Murine Model of Human T-cell Lymphoma
Salvia Jain; Xavier Jirau-Serrano; Kelly M. Zullo; Luigi Scotto; Carmine F. Palermo; Stephen A. Sastra; Kenneth P. Olive; Serge Cremers; Tiffany Thomas; Ying Wei; Yuan Zhang; Govind Bhagat; Jennifer E. Amengual; Changchun Deng; Charles Karan; Ronald Realubit; Susan E. Bates; Owen A. O'Connor
Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors
Sutapa Sinha; Justin Boysen; Michael Nelson; Charla Secreto; Steven L. Warner; David J. Bearss; Connie Lesnick; Tait D. Shanafelt; Neil E. Kay; Asish K. Ghosh
Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer
Vianey Gonzalez-Villasana; Enrique Fuentes-Mattei; Cristina Ivan; Heather J. Dalton; Cristian Rodriguez-Aguayo; Ricardo J. Fernandez-de Thomas; Burcu Aslan; Paloma del C. Monroig; Guermarie Velazquez-Torres; Rebecca A. Previs; Sunila Pradeep; Nermin Kahraman; Huamin Wang; Pinar Kanlikilicer; Bulent Ozpolat; George Calin; Anil K. Sood; Gabriel Lopez-Berestein
Biology of Human Tumors
The Impact of Clone Size on the Prognostic Value of Chromosome Aberrations by Fluorescence In Situ Hybridization in Multiple Myeloma
Gang An; Zengjun Li; Yu-Tzu Tai; Chirag Acharya; Qian Li; Xiaoqi Qin; Shuhua Yi; Yan Xu; Xiaoyan Feng; Chengwen Li; Jiawei Zhao; Lihui Shi; Meirong Zang; Shuhui Deng; Weiwei Sui; Mu Hao; Dehui Zou; Yaozhong Zhao; Junyuan Qi; Tao Cheng; Kun Ru; Jianxiang Wang; Kenneth C Anderson; Lugui Qiu
Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer
Sabrina Arena; Beatriz Bellosillo; Giulia Siravegna; Alejandro Martínez; Israel Cañadas; Luca Lazzari; Noelia Ferruz; Mariangela Russo; Sandra Misale; Iria González; Mar Iglesias; Elena Gavilan; Giorgio Corti; Sebastijan Hobor; Giovanni Crisafulli; Marta Salido; Juan Sánchez; Alba Dalmases; Joaquim Bellmunt; Gianni De Fabritiis; Ana Rovira; Federica Di Nicolantonio; Joan Albanell; Alberto Bardelli; Clara Montagut
IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma
Craig C. Carson; Stergios J. Moschos; Sharon N. Edmiston; David B. Darr; Nana Nikolaishvili-Feinberg; Pamela A. Groben; Xin Zhou; Pei Fen Kuan; Shaily Pandey; Keefe T. Chan; Jamie L. Jordan; Honglin Hao; Jill S. Frank; Dennis A. Hopkinson; David C. Gibbs; Virginia D. Alldredge; Eloise Parrish; Sara C. Hanna; Paula Berkowitz; David S. Rubenstein; C. Ryan Miller; James E. Bear; David W. Ollila; Norman E. Sharpless; Kathleen Conway; Nancy E. Thomas
Identification of Biological Relevant Minor Histocompatibility Antigens within the B-lymphocyte–Derived HLA-Ligandome Using a Reverse Immunology Approach
Pleun Hombrink; Chopie Hassan; Michel G.D. Kester; Lorenz Jahn; Margot J. Pont; Arnoud H. de Ru; Cornelis A.M. van Bergen; Marieke Griffioen; J.H. Frederik Falkenburg; Peter A. van Veelen; Mirjam H.M. Heemskerk
Letters to the Editor
Retraction
Corrections
Advertisement
