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15 September 2015
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Cover Image
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The cover shows a section of a benign peripheral nerve sheath tumor (plexiform neurofibroma) from a patient with neurofibromatosis type 1 (NF1). Hematoxylin and eosin staining reveals the abundant collagen deposition in this tumor. For details, see the article by Hirbe and colleagues on page 4201 of this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1078-0432
EISSN 1557-3265
Highlights
20th Anniversary Commentary
CCR Translations
CCR Perspectives in Drug Approval
FDA Approval: Blinatumomab
Donna Przepiorka; Chia-Wen Ko; Albert Deisseroth; Carolyn L. Yancey; Reyes Candau-Chacon; Haw-Jyh Chiu; Brenda J. Gehrke; Candace Gomez-Broughton; Robert C. Kane; Susan Kirshner; Nitin Mehrotra; Tiffany K. Ricks; Deborah Schmiel; Pengfei Song; Ping Zhao; Qing Zhou; Ann T. Farrell; Richard Pazdur
Molecular Pathways
Cancer Therapy: Clinical
Effects of Adjuvant Sorafenib and Sunitinib on Cardiac Function in Renal Cell Carcinoma Patients without Overt Metastases: Results from ASSURE, ECOG 2805
Naomi B. Haas; Judith Manola; Bonnie Ky; Keith T. Flaherty; Robert G. Uzzo; Christopher J. Kane; Michael Jewett; Lori Wood; Christopher G. Wood; Michael B. Atkins; Janice J. Dutcher; George Wilding; Robert S. DiPaola
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
Christine E. Brown; Behnam Badie; Michael E. Barish; Lihong Weng; Julie R. Ostberg; Wen-Chung Chang; Araceli Naranjo; Renate Starr; Jamie Wagner; Christine Wright; Yubo Zhai; James R. Bading; Julie A. Ressler; Jana Portnow; Massimo D'Apuzzo; Stephen J. Forman; Michael C. Jensen
Personalized Medicine and Imaging
Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy
Hui-Ming Chen; Ge Ma; Neil Gildener-Leapman; Samuel Eisenstein; Brian A. Coakley; Junko Ozao; John Mandeli; Celia Divino; Myron Schwartz; Max Sung; Robert Ferris; Johnny Kao; Lu-Hai Wang; Ping-Ying Pan; Eric C. Ko; Shu-Hsia Chen
Cancer Therapy: Preclinical
Aurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma
Kelly M. Zullo; Yige Guo; Laurence Cooke; Xavier Jirau-Serrano; Michael Mangone; Luigi Scotto; Jennifer E. Amengual; Yinghui Mao; Renu Nandakumar; Serge Cremers; Jimmy Duong; Daruka Mahadevan; Owen A. O'Connor
Pan-HER, an Antibody Mixture Simultaneously Targeting EGFR, HER2, and HER3, Effectively Overcomes Tumor Heterogeneity and Plasticity
Helle J. Jacobsen; Thomas T. Poulsen; Anna Dahlman; Ida Kjær; Klaus Koefoed; Jette W. Sen; Dietmar Weilguny; Bolette Bjerregaard; Christina R. Andersen; Ivan D. Horak; Mikkel W. Pedersen; Michael Kragh; Johan Lantto
Maintenance Treatment with Cetuximab and BAY86-9766 Increases Antitumor Efficacy of Irinotecan plus Cetuximab in Human Colorectal Cancer Xenograft Models
Teresa Troiani; Stefania Napolitano; Giulia Martini; Erika Martinelli; Claudia Cardone; Nicola Normanno; Donata Vitagliano; Floriana Morgillo; Francesca Fenizia; Matilde Lambiase; Luigi Formisano; Roberto Bianco; Davide Ciardiello; Fortunato Ciardiello
Author Choice
Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions
Marc Damelin; Alexander Bankovich; Albert Park; Jorge Aguilar; Wade Anderson; Marianne Santaguida; Monette Aujay; Sarah Fong; Kiran Khandke; Virginia Pulito; Elana Ernstoff; Paul Escarpe; Jeffrey Bernstein; Marybeth Pysz; Wenyan Zhong; Erik Upeslacis; Judy Lucas; Justin Lucas; Timothy Nichols; Kathryn Loving; Orit Foord; Johannes Hampl; Robert Stull; Frank Barletta; Hadi Falahatpisheh; Puja Sapra; Hans-Peter Gerber; Scott J. Dylla
Biology of Human Tumors
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing
Marina Parry; Matthew J.J. Rose-Zerilli; Viktor Ljungström; Jane Gibson; Jun Wang; Renata Walewska; Helen Parker; Anton Parker; Zadie Davis; Anne Gardiner; Neil McIver-Brown; Christina Kalpadakis; Aliki Xochelli; Achilles Anagnostopoulos; Claudia Fazi; David Gonzalez de Castro; Claire Dearden; Guy Pratt; Richard Rosenquist; Margaret Ashton-Key; Francesco Forconi; Andrew Collins; Paolo Ghia; Estella Matutes; Gerassimos Pangalis; Kostas Stamatopoulos; David Oscier; Jonathan C. Strefford
Author Choice
Gene Expression Profiling of Desmoid Tumors by cDNA Microarrays and Correlation with Progression-Free Survival
Sébastien Salas; Celine Brulard; Philippe Terrier; Dominique Ranchere-Vince; Agnes Neuville; Louis Guillou; Marick Lae; Agnes Leroux; Olivier Verola; Kurtz Jean-Emmanuel; Sylvie Bonvalot; Jean-Yves Blay; Axel Le Cesne; Alain Aurias; Jean-Michel Coindre; Frederic Chibon
Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma
Angela C. Hirbe; Sonika Dahiya; Christopher A. Miller; Tiandao Li; Robert S. Fulton; Xiaochun Zhang; Sandra McDonald; Katherine DeSchryver; Eric J. Duncavage; Jessica Walrath; Karlyne M. Reilly; Haley J. Abel; Melike Pekmezci; Arie Perry; Timothy J. Ley; David H. Gutmann
Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer
Grant D. Stewart; Fiach C. O'Mahony; Alexander Laird; Lel Eory; Alexander L.R. Lubbock; Alan Mackay; Jyoti Nanda; Marie O'Donnell; Peter Mullen; S. Alan McNeill; Antony C.P. Riddick; Daniel Berney; Axel Bex; Michael Aitchison; Ian M. Overton; David J. Harrison; Thomas Powles
Intratumoral CD14+ Cells and Circulating CD14+HLA-DRlo/neg Monocytes Correlate with Decreased Survival in Patients with Clear Cell Renal Cell Carcinoma
Michael P. Gustafson; Yi Lin; Jonathan S. Bleeker; Deepti Warad; Matthew K. Tollefson; Paul L. Crispen; Peggy A. Bulur; Susan M. Harrington; Rebecca R. Laborde; Dennis A. Gastineau; Bradley C. Leibovich; John C. Cheville; Eugene D. Kwon; Allan B. Dietz
Serum miR-21, miR-29a, and miR-125b Are Promising Biomarkers for the Early Detection of Colorectal Neoplasia
Atsushi Yamada; Takahiro Horimatsu; Yoshinaga Okugawa; Naoshi Nishida; Hajime Honjo; Hiroshi Ida; Tadayuki Kou; Toshihiro Kusaka; Yu Sasaki; Makato Yagi; Takuma Higurashi; Norio Yukawa; Yusuke Amanuma; Osamu Kikuchi; Manabu Muto; Yoshiyuki Ueno; Atsushi Nakajima; Tsutomu Chiba; C. Richard Boland; Ajay Goel
Corrections
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